thiazoles has been researched along with lurasidone hydrochloride in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (3.85) | 29.6817 |
| 2010's | 96 (92.31) | 24.3611 |
| 2020's | 4 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ishibashi, T; Ishiyama, T; Ito, A; Ohno, Y; Tokuda, K; Toma, S | 1 |
| Enomoto, T; Ishibashi, T; Ishiyama, T; Ito, A; Tokuda, K; Toma, S | 1 |
| Cucchiaro, J; Guarino, J; Loebel, A; Nakamura, M; Ogasa, M; Phillips, D; Severs, J | 1 |
| Loebel, AD; Meyer, JM; Schweizer, E | 1 |
| Horisawa, T; Ishibashi, T; Ishiyama, T; Ito, A; Matsumoto, K; Nakamura, M; Nishikawa, H; Ogasa, M; Ohno, Y; Oki, H; Saji, I; Tagashira, R; Tanno, N; Tokuda, K; Toma, S; Ueda, Y | 1 |
| Cucchiaro, J; Fox, KH; Harvey, PD; Keefe, RS; Loebel, A; Siu, C | 1 |
| Citrome, L | 6 |
| Cucchiaro, J; Harvey, PD; Keefe, RS; Loebel, A; Ogasa, M | 1 |
| Enomoto, T; Horisawa, T; Ishibashi, T; Ishiyama, T; Nishikawa, H; Taiji, M; Toma, S | 1 |
| Bolis, F; Calabrese, F; Fumagalli, F; Luoni, A; Racagni, G; Riva, MA | 1 |
| Baek, M; Ha, DJ; Kim, SJ; Koo, TS; Lee, J; Moon, H | 1 |
| Horiguchi, M; Huang, M; Meltzer, HY | 1 |
| Howland, RH | 1 |
| Caccia, S | 1 |
| Cucchiaro, J; Kalali, AH; Loebel, A; Meltzer, HY; Ogasa, M; Phillips, D; Pikalov, A; Schweizer, E; Silva, R; Xu, J | 1 |
| Chae, YJ; Koo, TS; Lee, KR | 1 |
| Guay, DR | 1 |
| Cucchiaro, J; Loebel, A; Ogasa, M; Potkin, SG | 1 |
| Grant, JS; Keltner, NL; Moore, RL | 1 |
| Horiguchi, M; Li, X; Meltzer, HY; Wei, J; Yan, Z; Yuen, EY | 1 |
| Owen, RT | 1 |
| Kane, JM | 1 |
| Horiguchi, M; Meltzer, HY | 1 |
| Hussar, DA | 1 |
| Citrome, L; Kantrowitz, JT | 1 |
| Citrome, L; Cucchiaro, J; Loebel, A; Phillips, D; Sarma, K; Silva, R; Tsuchiya, S | 1 |
| Felix, AR; Horiguchi, M; Huang, M; Meltzer, HY | 1 |
| Nolan, SF; Roman, MW | 1 |
| Alsuwaidan, M; Cha, DS; Jerrell, JM; McIntosh, D; McIntyre, RS; Powell, AM | 1 |
| Yasui-Furukori, N | 1 |
| Adelekun, AE; Hannaway, KE; Horiguchi, M; Jayathilake, K; Meltzer, HY | 1 |
| Hopkins, CR | 1 |
| Stahl, SM; Tarazi, FI | 1 |
| Doi, H; Horisawa, T; Kawasaki, A; Mizuma, H; Nakazawa, S; Nishimura, N; Onoe, H; Yokoyama, C | 1 |
| Correll, CU; De Hert, M; Detraux, J; Sweers, K; van Winkel, R; Yu, W | 1 |
| Guarino, J; Kimura, T; Nakamura, M; Ogasa, M | 1 |
| Horisawa, T; Ichikawa, O; Maruyama, M; Nagata, R; Nakahira, H; Okazaki, K; Tokuda, K; Yamazaki, K | 1 |
| Calabrese, F; Fumagalli, F; Guidotti, G; Luoni, A; Racagni, G; Riva, MA | 1 |
| Cazzaniga, G; Homberg, JR; Hulsken, S; Luoni, A; Racagni, G; Riva, MA | 1 |
| Sanford, M | 1 |
| Bobo, WV | 1 |
| Horisawa, T; Ishibashi, T; Ishiyama, T; Ono, M; Taiji, M | 1 |
| Horiguchi, M; Horisawa, T; Ikeda, A; Ishiyama, T; Nishikawa, H; Ono, M; Taiji, M; Toma, S | 1 |
| Cucchiaro, J; Hsu, C; Kalali, AH; Loebel, A; Pikalov, A; Potkin, SG; Sarma, K; Xu, L | 1 |
| Cates, LN; Hedlund, PB; Huitron-Resendiz, S; Roberts, AJ | 1 |
| Cucchiaro, J; Hsu, J; Loebel, A; Nasrallah, HA; Phillips, D; Silva, R; Xu, J | 1 |
| Ikeda, K; Ikejiri, M; Ishiyama, T; Murai, T; Nakako, T; Taiji, M | 2 |
| Citrome, L; Cucchiaro, J; Hernandez, D; Hsu, J; Loebel, A; McEvoy, JP; Pikalov, A | 1 |
| Cucchiaro, J; Hsu, J; Loebel, A; Pikalov, A; Simonelli, D; Stahl, SM | 1 |
| Amrutheshwar, R; Dkhar, SA; George, M; Kattimani, S; Rajkumar, RP | 1 |
| Cucchiaro, J; Kane, JM; Loebel, A; Pikalov, A; Sarma, K; Xu, J | 1 |
| Brašić, JR; Gean, EG; Kuwabara, H; Loebel, A; Maini, A; Stock, T; Wong, DF | 1 |
| Grossman, F; Hassan, M; Meyer, K; O'Day, K; Rajagopalan, K | 1 |
| Loebel, A; Meyer, K; O'Day, K; Pikalov, A; Rajagopalan, K | 1 |
| Riva, MA; Tarazi, FI | 1 |
| Mehta, MU; Rogers, H; Uppoor, RS; Younis, IR; Zhang, H; Zhu, H | 1 |
| Chiu, YY; Ereshefsky, L; Loebel, A; Poola, N; Preskorn, S | 1 |
| Cucchiaro, J; Harvey, PD; Hsu, J; Loebel, A; Maruff, P; Siu, CO | 1 |
| Keator, DB; Kesler-West, ML; Mukherjee, J; Nguyen, DD; Potkin, SG; Preda, A; Shah, N; van Erp, TG | 1 |
| Huang, M; Kwon, S; Meltzer, HY; Oyamada, Y; Panos, JJ; Rajagopal, L | 1 |
| Cucchiaro, J; Hsu, J; Kroger, H; Loebel, A; Sachs, G; Sarma, K; Silva, R | 1 |
| Calabrese, JR; Cucchiaro, J; Kroger, H; Loebel, A; Sarma, K; Silva, R; Xu, J | 1 |
| Belmaker, RH | 1 |
| Cha, DS; Kim, RD; Mansur, RB; McIntyre, RS | 1 |
| Citrome, L; Cucchiaro, J; Ketter, TA; Loebel, A | 1 |
| Diefenderfer, LA; Iuppa, CA | 1 |
| Cucchiaro, JB; Harvey, PD; Loebel, AD; Pikalov, AA; Siu, CO | 1 |
| Luoni, A; Riva, MA; Rocha, FF | 1 |
| Bellisario, V; Berry, A; Calabrese, F; Capoccia, S; Cirulli, F; Gass, P; Luoni, A; Riva, MA | 1 |
| Awad, G; Hassan, M; Hsu, J; Loebel, A; Pikalov, A; Rajagopalan, K | 1 |
| Alamo, C; García-García, P; López-Muñoz, F | 1 |
| Ketter, TA | 1 |
| Chiu, YY; Ereshefsky, L; Loebel, A; Poola, N; Preskorn, SH | 1 |
| Cucchiaro, JB; Loebel, AD; Mao, Y; Nasrallah, HA; Pikalov, AA | 1 |
| Morrissette, DA; Stahl, SM | 1 |
| Coffey, DB; McLaren, JL; Millard, PH | 1 |
| Hashimoto, T; Ikeda, K; Ikejiri, M; Konoike, N; Kotani, M; Manabe, S; Matsumoto, K; Murai, T; Nakako, T; Nakamura, K; Ogi, Y | 1 |
| Ikeda, K; Murai, T; Nakamichi, K; Shimizu, I | 1 |
| Asiri, YI; Barr, AM; Boyda, HN; Honer, WG; Pang, CC; Procyshyn, RM; Wang, CK; Wu, C; Yuen, J | 1 |
| Cornelius, V; Smith, L; Taylor, DM; Young, AH | 1 |
| Catalano, G; Catalano, MC; Grimsich, LC; Molnar, GP | 1 |
| McElroy, SL | 1 |
| Ben Gharbia, M; Garnier, M; Llorca, PM; Samalin, L | 1 |
| Dharavath, S; Kalariya, PD; Kumar Talluri, MVN; Prasanth, B; Srinivas, R | 1 |
| Alarcon, RD; Biernacka, JM; Bobo, WV; Choi, DS; Frye, MA; Kung, S; Moore, KM; Prieto, ML; Tye, SJ; Veldic, M | 1 |
| Calabrese, JR; Citrome, L; Dell'Osso, B; Frye, MA; Ketter, TA; Miller, S | 1 |
| Calabrese, JR; Carta, MG; Moro, MF; Nardi, AE | 1 |
| Ketter, TA; Miller, S; Wang, PW | 1 |
| Cucchiaro, J; Kroger, H; Loebel, A; McIntyre, RS; Pikalov, A | 1 |
| Loebel, A; Meyer, N; Rajagopalan, K; Wade, S | 1 |
| Kou, C; Liu, X; Liu, Y; Ma, Y; Song, Y; Su, Y; Wang, M; Yang, G; You, Y; Zhang, L; Zhang, Y | 1 |
| Carvalho, AF; Hidalgo-Mazzei, D; Murru, A; Pacchiarotti, I; Samalin, L; Verdolini, N; Vieta, E; Young, AH | 1 |
| Patel, MH; Sawant, KK | 1 |
| Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S | 1 |
| Broder, MS; Chang, E; Greene, M; Houle, CR; Tarbox, MH; Waters, HC; Yan, T | 1 |
| Harvey, PD; Loebel, A; Miller, BJ; Newcomer, JW; Pikalov, A; Siu, CO; Tocco, M; Tsai, J | 1 |
| Horikoshi, S; Ichinose, M; Miura, I; Suzuki, Y; Watanabe, K | 1 |
37 review(s) available for thiazoles and lurasidone hydrochloride
| Article | Year |
|---|---|
Lurasidone: a new drug in development for schizophrenia.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Clinical Trials, Phase II as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2009 |
Lurasidone for schizophrenia: a review of the efficacy and safety profile for this newly approved second-generation antipsychotic.
Topics: Administration, Oral; Antipsychotic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Drug Interactions; Drug Labeling; Humans; Isoindoles; Lurasidone Hydrochloride; Numbers Needed To Treat; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Treatment Outcome | 2011 |
Lurasidone for schizophrenia: a brief review of a new second-generation antipsychotic.
Topics: Akathisia, Drug-Induced; Animals; Antipsychotic Agents; Disorders of Excessive Somnolence; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Humans; Isoindoles; Lurasidone Hydrochloride; Randomized Controlled Trials as Topic; Schizophrenia; Serotonin 5-HT2 Receptor Antagonists; Thiazoles; Treatment Outcome; United States; United States Food and Drug Administration; Weight Gain | 2011 |
Iloperidone, asenapine, and lurasidone: a brief overview of 3 new second-generation antipsychotics.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles | 2011 |
Pharmacokinetics and metabolism update for some recent antipsychotics.
Topics: Animals; Antipsychotic Agents; Aripiprazole; Drug Interactions; Humans; Inactivation, Metabolic; Isoindoles; Lurasidone Hydrochloride; Piperazines; Quinolones; Thiazoles | 2011 |
Lurasidone: a new treatment option for schizophrenia.
Topics: Antipsychotic Agents; Clinical Trials as Topic; Drug Interactions; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2011 |
Lurasidone: a clinical overview.
Topics: Antipsychotic Agents; Blood Glucose; Body Weight; Humans; Hypotension, Orthostatic; Isoindoles; Long QT Syndrome; Lurasidone Hydrochloride; Schizophrenia; Thiazoles; Treatment Outcome | 2011 |
Lurasidone for schizophrenia: what's different?
Topics: Antipsychotic Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2012 |
Lurasidone (latuda®): an atypical antipsychotic.
Topics: Antipsychotic Agents; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2012 |
A review of published evidence reporting on the efficacy and pharmacology of lurasidone.
Topics: Bipolar Disorder; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cognition Disorders; Double-Blind Method; Humans; Isoindoles; Lurasidone Hydrochloride; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles | 2012 |
Update on the development of lurasidone as a treatment for patients with acute schizophrenia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Clinical Trials as Topic; Cognition; Humans; Isoindoles; Lurasidone Hydrochloride; Metabolomics; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Schizophrenia; Thiazoles | 2012 |
ACS chemical neuroscience molecule spotlight on latuda (lurasidone; SM-13,496).
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Dopamine Antagonists; Humans; Isoindoles; Lurasidone Hydrochloride; Neurosciences; Schizophrenia; Serotonin Antagonists; Serotonin Receptor Agonists; Societies, Scientific; Thiazoles | 2011 |
Iloperidone, asenapine and lurasidone: a primer on their current status.
Topics: Adult; Animals; Antipsychotic Agents; Bipolar Disorder; Dibenzocycloheptenes; Drug Approval; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles; United States; United States Food and Drug Administration | 2012 |
Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.
Topics: Antipsychotic Agents; Bipolar Disorder; Blood Glucose; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lipid Metabolism; Lurasidone Hydrochloride; Paliperidone Palmitate; Piperidines; Pyrimidines; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Weight Gain | 2012 |
Lurasidone in schizophrenia: new information about dosage and place in therapy.
Topics: Antipsychotic Agents; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles; Treatment Outcome | 2012 |
Lurasidone : in the treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles; Time Factors | 2013 |
Asenapine, iloperidone and lurasidone: critical appraisal of the most recently approved pharmacotherapies for schizophrenia in adults.
Topics: Antipsychotic Agents; Dibenzocycloheptenes; Drug Approval; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperidines; Schizophrenia; Thiazoles | 2013 |
Newer antipsychotics and upcoming molecules for schizophrenia.
Topics: Antipsychotic Agents; Dibenzocycloheptenes; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Piperazines; Piperidines; Schizophrenia; Thiazoles | 2013 |
The preclinical profile of lurasidone: clinical relevance for the treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2013 |
An integrated clinical pharmacology approach for deriving dosing recommendations in a regulatory setting: review of recent cases in psychiatry drugs.
Topics: Antipsychotic Agents; Central Nervous System Stimulants; Drug Approval; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Methylphenidate; Paliperidone Palmitate; Pharmacology, Clinical; Pimozide; Pyrimidines; Thiazoles | 2013 |
A review of FDA-approved treatment options in bipolar depression.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzhydryl Compounds; Benzodiazepines; Bipolar Disorder; Central Nervous System Stimulants; Depressive Disorder; Dibenzothiazepines; Drug Approval; Drug Combinations; Excitatory Amino Acid Antagonists; Fluoxetine; Humans; Isoindoles; Ketamine; Lamotrigine; Lurasidone Hydrochloride; Modafinil; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Thiazoles; Triazines; United States; United States Food and Drug Administration | 2013 |
Clinical assessment of lurasidone benefit and risk in the treatment of bipolar I depression using number needed to treat, number needed to harm, and likelihood to be helped or harmed.
Topics: Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Isoindoles; Lurasidone Hydrochloride; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Assessment; Thiazoles; Treatment Outcome | 2014 |
The effectiveness of lurasidone as an adjunct to lithium or divalproex in the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Isoindoles; Lithium; Lurasidone Hydrochloride; Thiazoles; Treatment Outcome; Valproic Acid | 2014 |
Acute and maintenance treatments for bipolar depression.
Topics: Acute Disease; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depression; Dibenzothiazepines; Drug Therapy, Combination; Fluoxetine; Humans; Isoindoles; Lurasidone Hydrochloride; Olanzapine; Quetiapine Fumarate; Selective Serotonin Reuptake Inhibitors; Thiazoles | 2014 |
Lurasidone drug-drug interaction studies: a comprehensive review.
Topics: Antipsychotic Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Drug Therapy, Combination; Humans; Isoindoles; Ketoconazole; Lithium Compounds; Lurasidone Hydrochloride; Rifampin; Thiazoles | 2014 |
Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy.
Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Clozapine; Dibenzocycloheptenes; Drug Therapy, Combination; Heterocyclic Compounds, 4 or More Rings; Humans; Impulsive Behavior; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Thiazoles; Violence | 2014 |
Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Depression; Dibenzothiazepines; Drug Therapy, Combination; Fluoxetine; Humans; Isoindoles; Lamotrigine; Lithium Compounds; Lurasidone Hydrochloride; Monoamine Oxidase Inhibitors; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles; Treatment Outcome; Triazines; Valproic Acid | 2014 |
Treatment of bipolar depression: making sensible decisions.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorder, Major; Dibenzothiazepines; Drug Combinations; Drug Therapy, Combination; Fluoxetine; Humans; Isoindoles; Lithium Compounds; Lurasidone Hydrochloride; Quetiapine Fumarate; Thiazoles; Valproic Acid | 2014 |
[Short-term efficacy and safety of lurasidone in the treatment of schizophrenia].
Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Isoindoles; Lurasidone Hydrochloride; No-Observed-Adverse-Effect Level; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome | 2014 |
Current landscape, unmet needs, and future directions for treatment of bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Benzodiazepines; Bipolar Disorder; Dibenzothiazepines; Drug Combinations; Fluoxetine; Forecasting; Health Services Needs and Demand; Humans; Isoindoles; Lamotrigine; Lurasidone Hydrochloride; Psychotherapy; Quetiapine Fumarate; Thiazoles; Triazines | 2014 |
Balancing benefits and harms of treatments for acute bipolar depression.
Topics: Acute Disease; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dibenzothiazepines; Drug Combinations; Fluoxetine; Humans; Isoindoles; Lamotrigine; Lurasidone Hydrochloride; Multicenter Studies as Topic; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Thiazoles; Triazines; Weight Gain | 2014 |
Potential use of lurasidone for the treatment of bipolar psychosis.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Humans; Isoindoles; Lurasidone Hydrochloride; Psychotic Disorders; Schizophrenia; Thiazoles | 2015 |
Bipolar therapeutics update 2014: A tale of 3 treatments.
Topics: Antipsychotic Agents; Benzhydryl Compounds; Bipolar Disorder; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Drug Discovery; Humans; Isoindoles; Lurasidone Hydrochloride; Modafinil; Piperazines; Thiazoles | 2015 |
The metabolic side effects of 12 antipsychotic drugs used for the treatment of schizophrenia on glucose: a network meta-analysis.
Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Humans; Insulin; Lurasidone Hydrochloride; Network Meta-Analysis; Olanzapine; Piperazines; Risperidone; Schizophrenia; Thiazoles | 2017 |
Mixed states in bipolar and major depressive disorders: systematic review and quality appraisal of guidelines.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Practice Guidelines as Topic; Quetiapine Fumarate; Thiazoles; Valproic Acid | 2018 |
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes | 2020 |
Lurasidone for the Treatment of Schizophrenia: Design, Development, and Place in Therapy.
Topics: Antipsychotic Agents; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Serotonin; Thiazoles; Weight Gain | 2023 |
23 trial(s) available for thiazoles and lurasidone hydrochloride
| Article | Year |
|---|---|
Lurasidone in the treatment of acute schizophrenia: a double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Psychometrics; Schizophrenia; Schizophrenic Psychology; Thiazoles; Treatment Outcome; Young Adult | 2009 |
Characteristics of the MATRICS Consensus Cognitive Battery in a 29-site antipsychotic schizophrenia clinical trial.
Topics: Adult; Antipsychotic Agents; Cognition Disorders; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles | 2011 |
Performance and interview-based assessments of cognitive change in a randomized, double-blind comparison of lurasidone vs. ziprasidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cognition Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Interview, Psychological; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thiazoles; Young Adult | 2011 |
Lurasidone in the treatment of schizophrenia: a randomized, double-blind, placebo- and olanzapine-controlled study.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Olanzapine; Patient Admission; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Treatment Outcome | 2011 |
Double-blind comparison of the safety and efficacy of lurasidone and ziprasidone in clinically stable outpatients with schizophrenia or schizoaffective disorder.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Body Weight; Cholesterol; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Outpatients; Piperazines; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome; Triglycerides; Young Adult | 2011 |
Long-term safety and tolerability of lurasidone in schizophrenia: a 12-month, double-blind, active-controlled study.
Topics: Adult; Ambulatory Care; Analysis of Variance; Antipsychotic Agents; Croatia; Double-Blind Method; Female; Humans; Isoindoles; Israel; Kaplan-Meier Estimate; Lurasidone Hydrochloride; Male; Middle Aged; Proportional Hazards Models; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; South Africa; South America; Thailand; Thiazoles; Time Factors; Treatment Outcome; United States | 2012 |
Lurasidone for the acute treatment of adults with schizophrenia: what is the number needed to treat, number needed to harm, and likelihood to be helped or harmed?
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Blood Glucose; Cholesterol; Dibenzothiazepines; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Isoindoles; Likelihood Functions; Lurasidone Hydrochloride; Male; Medication Adherence; Nausea; Numbers Needed To Treat; Olanzapine; Psychiatric Status Rating Scales; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Research Design; Schizophrenia; Thiazoles; Treatment Outcome; Triglycerides; Weight Gain | 2012 |
Lurasidone in the treatment of schizophrenia: a 6-week, placebo-controlled study.
Topics: Adolescent; Adult; Analysis of Variance; Antipsychotic Agents; Brief Psychiatric Rating Scale; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Single-Blind Method; Thiazoles; Young Adult | 2013 |
Efficacy and safety of lurasidone 80 mg/day and 160 mg/day in the treatment of schizophrenia: a randomized, double-blind, placebo- and active-controlled trial.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Body Mass Index; Body Weight; Dibenzothiazepines; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Models, Statistical; Prospective Studies; Psychiatric Status Rating Scales; Quetiapine Fumarate; Schizophrenia; Severity of Illness Index; Thiazoles; Time Factors; Waist Circumference; Young Adult | 2013 |
Lurasidone for the treatment of acutely psychotic patients with schizophrenia: a 6-week, randomized, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; International Cooperation; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Thiazoles; Treatment Outcome; Young Adult | 2013 |
Effectiveness of lurasidone in patients with schizophrenia or schizoaffective disorder switched from other antipsychotics: a randomized, 6-week, open-label study.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Dibenzothiazepines; Drug Administration Schedule; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Olanzapine; Psychotic Disorders; Quetiapine Fumarate; Schizophrenia; Thiazoles; Time Factors; Treatment Failure; Treatment Outcome | 2013 |
Effectiveness of lurasidone for patients with schizophrenia following 6 weeks of acute treatment with lurasidone, olanzapine, or placebo: a 6-month, open-label, extension study.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Administration Schedule; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Olanzapine; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome | 2013 |
Effectiveness of lurasidone vs. quetiapine XR for relapse prevention in schizophrenia: a 12-month, double-blind, noninferiority study.
Topics: Adult; Antipsychotic Agents; Dibenzothiazepines; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Isoindoles; Kaplan-Meier Estimate; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Schizophrenia; Secondary Prevention; Thiazoles; Treatment Outcome | 2013 |
Annual cost of relapses and relapse-related hospitalizations in adults with schizophrenia: results from a 12-month, double-blind, comparative study of lurasidone vs quetiapine extended-release.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cost-Benefit Analysis; Delayed-Action Preparations; Dibenzothiazepines; Double-Blind Method; Female; Health Services; Hospitalization; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Mental Health Services; Middle Aged; Models, Economic; Quetiapine Fumarate; Schizophrenia; Thiazoles; Young Adult | 2013 |
Effect of food on the pharmacokinetics of lurasidone: results of two randomized, open-label, crossover studies.
Topics: Adult; Cross-Over Studies; Female; Food-Drug Interactions; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Schizophrenia; Thiazoles | 2013 |
Effect of lurasidone on neurocognitive performance in patients with schizophrenia: a short-term placebo- and active-controlled study followed by a 6-month double-blind extension.
Topics: Adult; Antipsychotic Agents; Cognition; Delayed-Action Preparations; Dibenzothiazepines; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Psychiatric Status Rating Scales; Quetiapine Fumarate; Schizophrenia; Schizophrenic Psychology; Thiazoles; Time Factors | 2013 |
D2 receptor occupancy following lurasidone treatment in patients with schizophrenia or schizoaffective disorder.
Topics: Adult; Algorithms; Antipsychotic Agents; Benzamides; Brain; Dose-Response Relationship, Drug; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Positron-Emission Tomography; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Statistics as Topic; Thiazoles; Young Adult | 2014 |
Lurasidone monotherapy in the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Thiazoles; Treatment Outcome | 2014 |
Lurasidone as adjunctive therapy with lithium or valproate for the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoindoles; Lithium Compounds; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Thiazoles; Valproic Acid | 2014 |
Daytime sleepiness associated with lurasidone and quetiapine XR: results from a randomized double-blind, placebo-controlled trial in patients with schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cognition Disorders; Dibenzothiazepines; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Quetiapine Fumarate; Schizophrenia; Thiazoles; Treatment Outcome; Young Adult | 2014 |
Health-related quality of life among patients treated with lurasidone: results from a switch trial in patients with schizophrenia.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Dibenzothiazepines; Drug Substitution; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Olanzapine; Outpatients; Piperazines; Quality of Life; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome | 2014 |
Lurasidone for the treatment of depressive symptoms in schizophrenia: analysis of 4 pooled, 6-week, placebo-controlled studies.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Depressive Disorder; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Young Adult | 2015 |
Lurasidone in the treatment of bipolar depression with mixed (subsyndromal hypomanic) features: post hoc analysis of a randomized placebo-controlled trial.
Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Middle Aged; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Thiazoles | 2015 |
44 other study(ies) available for thiazoles and lurasidone hydrochloride
| Article | Year |
|---|---|
Lurasidone (SM-13496), a novel atypical antipsychotic drug, reverses MK-801-induced impairment of learning and memory in the rat passive-avoidance test.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Isoindoles; Lurasidone Hydrochloride; Male; Memory; Rats; Rats, Wistar; Reaction Time; Serotonin 5-HT2 Receptor Antagonists; Thiazoles | 2007 |
Lurasidone reverses MK-801-induced impairment of learning and memory in the Morris water maze and radial-arm maze tests in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Isoindoles; Learning Disabilities; Lurasidone Hydrochloride; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Swimming; Thiazoles | 2008 |
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity.
Topics: Animals; Antipsychotic Agents; Anxiety; Behavior, Animal; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dopamine; Guinea Pigs; Humans; Hyperkinesis; Isoindoles; Ligands; Lurasidone Hydrochloride; Male; Mice; Mice, Inbred Strains; Molecular Structure; Protein Binding; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Thiazoles; Transfection; Tremor | 2010 |
The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: mechanistic implications for the beneficial effects of the novel
Topics: Animals; Avoidance Learning; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Isoindoles; Learning Disabilities; Lurasidone Hydrochloride; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Agents; Thiazoles; Time Factors | 2011 |
Modulation of BDNF expression by repeated treatment with the novel antipsychotic lurasidone under basal condition and in response to acute stress.
Topics: Acute Disease; Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Gene Expression Regulation; Isoindoles; Lurasidone Hydrochloride; Male; Rats; Rats, Sprague-Dawley; Stress, Psychological; Thiazoles | 2012 |
Lurasidone (Latuda) for schizophrenia.
Topics: Antipsychotic Agents; Contraindications; Controlled Clinical Trials as Topic; Drug Interactions; Humans; Isoindoles; Lurasidone Hydrochloride; Schizophrenia; Thiazoles | 2011 |
Quantification of lurasidone, an atypical antipsychotic drug, in rat plasma with high-performance liquid chromatography with tandem mass spectrometry.
Topics: Acetonitriles; Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Isoindoles; Linear Models; Lurasidone Hydrochloride; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Thiazoles | 2011 |
Interaction of mGlu2/3 agonism with clozapine and lurasidone to restore novel object recognition in subchronic phencyclidine-treated rats.
Topics: Amino Acids; Animals; Antipsychotic Agents; Bridged Bicyclo Compounds, Heterocyclic; Clozapine; Cognition; Drug Agonism; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Isoindoles; Lurasidone Hydrochloride; Phencyclidine; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Metabotropic Glutamate; Recognition, Psychology; Thiazoles | 2011 |
Update on newer antipsychotic drugs.
Topics: Adult; Aged; Antipsychotic Agents; Bipolar Disorder; Child; Clinical Trials as Topic; Dibenzocycloheptenes; Female; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lurasidone Hydrochloride; Male; Piperidines; Pregnancy; Schizophrenia; Thiazoles; Treatment Outcome | 2011 |
Pharmacokinetics of lurasidone, a novel atypical anti-psychotic drug, in rats.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Injections, Intravenous; Isoindoles; Lurasidone Hydrochloride; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reference Standards; Thiazoles | 2011 |
Comment on the potential utility of the new atypical antipsychotic lurasidone in the geriatric population.
Topics: Age Factors; Aged; Antipsychotic Agents; Geriatrics; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Thiazoles | 2011 |
Biological perspectives: update on newer antipsychotic drugs: are they evidence based?
Topics: Antipsychotic Agents; Cyclooxygenase 2 Inhibitors; Dibenzocycloheptenes; Evidence-Based Medicine; Heterocyclic Compounds, 4 or More Rings; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Isoindoles; Isoxazoles; Lactones; Lurasidone Hydrochloride; Piperidines; Psychotic Disorders; Pyridines; Serotonin Receptor Agonists; Sulfones; Thiazoles | 2011 |
The novel antipsychotic drug lurasidone enhances N-methyl-D-aspartate receptor-mediated synaptic responses.
Topics: Animals; Antipsychotic Agents; Clozapine; Cognition Disorders; Disease Models, Animal; Isoindoles; Lurasidone Hydrochloride; Rats; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission; Thiazoles | 2012 |
The role of 5-HT1A receptors in phencyclidine (PCP)-induced novel object recognition (NOR) deficit in rats.
Topics: Animals; Antipsychotic Agents; Drug Therapy, Combination; Female; Hallucinogens; Isoindoles; Lurasidone Hydrochloride; Phencyclidine; Piperazines; Pyrimidines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Recognition, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Thiazoles | 2012 |
New drugs 2012 part I.
Topics: Aminopyridines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzamides; Benzazepines; Benzimidazoles; Benzofurans; Ceftaroline; Cephalosporins; Cyclopropanes; Drug Approval; Drug Combinations; Humans; Imidazoles; Indoles; Isoindoles; Linagliptin; Lurasidone Hydrochloride; Macrolides; Oxadiazoles; Piperazines; Proline; Purines; Quinazolines; Thiazoles; United States; Vilazodone Hydrochloride | 2012 |
5-HT1A and 5-HT7 receptors contribute to lurasidone-induced dopamine efflux.
Topics: Animals; Disease Models, Animal; Dopamine; Hippocampus; Isoindoles; Lurasidone Hydrochloride; Male; Nucleus Accumbens; Phenols; Piperazines; Prefrontal Cortex; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Sulfonamides; Thiazoles | 2012 |
Prevention of the phencyclidine-induced impairment in novel object recognition in female rats by co-administration of lurasidone or tandospirone, a 5-HT(1A) partial agonist.
Topics: Animals; Cognition Disorders; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Isoindoles; Lurasidone Hydrochloride; Phencyclidine; Piperazines; Piperidines; Pyridines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Thiazoles; Urea | 2012 |
Evaluation of dopamine D₂/D₃ and serotonin 5-HT₂A receptor occupancy for a novel antipsychotic, lurasidone, in conscious common marmosets using small-animal positron emission tomography.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Callithrix; Corpus Striatum; Isoindoles; Lurasidone Hydrochloride; Male; Olanzapine; Positron-Emission Tomography; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Thiazoles | 2013 |
Structural insight into receptor-selectivity for lurasidone.
Topics: Amino Acid Sequence; Humans; Isoindoles; Lurasidone Hydrochloride; Molecular Sequence Data; Receptors, Neurotransmitter; Sequence Homology, Amino Acid; Thiazoles | 2012 |
Modulation of neuronal plasticity following chronic concomitant administration of the novel antipsychotic lurasidone with the mood stabilizer valproic acid.
Topics: Affect; Animals; Antipsychotic Agents; Brain-Derived Neurotrophic Factor; Drug Therapy, Combination; Gene Expression; Hippocampus; Isoindoles; Lurasidone Hydrochloride; Male; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Thiazoles; Valproic Acid | 2013 |
Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Antigens, Differentiation; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Disease Models, Animal; Extinction, Psychological; Fear; Gene Expression Regulation; Isoindoles; Lurasidone Hydrochloride; Mood Disorders; Neuronal Plasticity; Prefrontal Cortex; Protein Transport; Rats; Rats, Transgenic; Rats, Wistar; Receptors, GABA; Receptors, Glucocorticoid; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Thiazoles; Vesicular Inhibitory Amino Acid Transport Proteins | 2013 |
Binding of lurasidone, a novel antipsychotic, to rat 5-HT7 receptor: analysis by [3H]SB-269970 autoradiography.
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; CHO Cells; Cricetinae; Isoindoles; Lurasidone Hydrochloride; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Thiazoles | 2013 |
The role of 5-HT7 receptor antagonism in the amelioration of MK-801-induced learning and memory deficits by the novel atypical antipsychotic drug lurasidone.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dizocilpine Maleate; Dopamine Antagonists; Isoindoles; Ketanserin; Lurasidone Hydrochloride; Male; Memory; Phenols; Pyrazoles; Pyrrolidines; Raclopride; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrahydronaphthalenes; Thiazoles | 2013 |
Effects of lurasidone in behavioral models of depression. Role of the 5-HT₇ receptor subtype.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Isoindoles; Lurasidone Hydrochloride; Male; Mice; Mice, Knockout; Receptors, Serotonin; Serotonin Antagonists; Thiazoles | 2013 |
Effects of lurasidone on executive function in common marmosets.
Topics: Animals; Antipsychotic Agents; Callithrix; Dose-Response Relationship, Drug; Executive Function; Exploratory Behavior; Female; Isoindoles; Lurasidone Hydrochloride; Male; Spatial Behavior; Thiazoles; Time Factors | 2013 |
Determination of dopamine D₂ receptor occupancy by lurasidone using positron emission tomography in healthy male subjects.
Topics: Adolescent; Adult; Antipsychotic Agents; Area Under Curve; Brain; Brain Mapping; Cohort Studies; Dose-Response Relationship, Drug; Fasting; Healthy Volunteers; Humans; Isoindoles; Lurasidone Hydrochloride; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Protein Binding; Receptors, Dopamine D2; Thiazoles; Young Adult | 2013 |
Cost-effectiveness of lurasidone vs aripiprazole among patients with schizophrenia who have previously failed on an atypical antipsychotic: an indirect comparison of outcomes from clinical trial data.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Cardiovascular Diseases; Clinical Trials as Topic; Clozapine; Comorbidity; Cost-Benefit Analysis; Diabetes Mellitus; Hospitalization; Humans; Isoindoles; Lurasidone Hydrochloride; Markov Chains; Models, Economic; Outcome Assessment, Health Care; Piperazines; Quinolones; Recurrence; Schizophrenia; Thiazoles; United States | 2013 |
Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5-HT)2A and DA D2 antagonism and 5-HT1A partial agonism.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Brain; Cerebral Cortex; Dopamine; Glutamic Acid; Hippocampus; Isoindoles; Lurasidone Hydrochloride; Male; Microdialysis; Neurotransmitter Agents; Nucleus Accumbens; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Synaptic Transmission; Thiazoles | 2014 |
Lurasidone and bipolar disorder.
Topics: Bipolar Disorder; Female; Humans; Isoindoles; Lithium Compounds; Lurasidone Hydrochloride; Male; Thiazoles; Valproic Acid | 2014 |
Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine.
Topics: Adult; Antipsychotic Agents; Child Development Disorders, Pervasive; Chlorpromazine; Gait Ataxia; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Multiple Sclerosis; Recurrence; Risperidone; Syndrome; Thiazoles | 2013 |
Lack of dopamine D4 receptor affinity contributes to the procognitive effect of lurasidone.
Topics: Animals; Antipsychotic Agents; Callithrix; Cognition; Conditioning, Operant; Dopamine Agents; Dose-Response Relationship, Drug; Female; Isoindoles; Lurasidone Hydrochloride; Male; Mental Recall; Protein Binding; Pyridines; Pyrimidines; Pyrroles; Receptors, Dopamine D4; Thiazoles | 2014 |
Anatomical specificity in the modulation of activity-regulated genes after acute or chronic lurasidone treatment.
Topics: Animals; Antipsychotic Agents; Basic Helix-Loop-Helix Transcription Factors; Brain-Derived Neurotrophic Factor; Corpus Striatum; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Growth Response Protein 1; Hippocampus; Isoindoles; Lurasidone Hydrochloride; Male; Nerve Tissue Proteins; Neuronal Plasticity; Prefrontal Cortex; Rats; Thiazoles | 2014 |
Delayed BDNF alterations in the prefrontal cortex of rats exposed to prenatal stress: preventive effect of lurasidone treatment during adolescence.
Topics: Animals; Antipsychotic Agents; Blotting, Western; Brain-Derived Neurotrophic Factor; Female; Isoindoles; Lurasidone Hydrochloride; Male; Neuroprotective Agents; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; Stress, Psychological; Thiazoles | 2014 |
Lurasidone treatment in a child with autism spectrum disorder with irritability and aggression.
Topics: Adolescent; Aggression; Antipsychotic Agents; Child Development Disorders, Pervasive; Humans; Irritable Mood; Isoindoles; Lurasidone Hydrochloride; Male; Thiazoles | 2014 |
Effects of lurasidone on ketamine-induced joint visual attention dysfunction as a possible disease model of autism spectrum disorders in common marmosets.
Topics: Animals; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Callithrix; Child Development Disorders, Pervasive; Cues; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Isoindoles; Ketamine; Lurasidone Hydrochloride; Male; Severity of Illness Index; Thiazoles | 2014 |
Lurasidone suppresses rapid eye movement sleep and improves sleep quality in rats.
Topics: Animals; Antipsychotic Agents; Electroencephalography; Isoindoles; Lurasidone Hydrochloride; Male; Rats, Wistar; Schizophrenia; Sleep Wake Disorders; Sleep, REM; Thiazoles; Wakefulness | 2014 |
An evaluation of the effects of the novel antipsychotic drug lurasidone on glucose tolerance and insulin resistance: a comparison with olanzapine.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Insulin Resistance; Isoindoles; Lurasidone Hydrochloride; Olanzapine; Rats; Rats, Sprague-Dawley; Thiazoles | 2014 |
Acute lurasidone overdose.
Topics: Adult; Antipsychotic Agents; Drug Overdose; Humans; Isoindoles; Lurasidone Hydrochloride; Male; Thiazoles | 2014 |
Pros and cons of approved therapies for bipolar depression and ongoing unmet needs.
Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dibenzothiazepines; Drug Combinations; Fluoxetine; Humans; Isoindoles; Lurasidone Hydrochloride; Quetiapine Fumarate; Thiazoles | 2014 |
Structural characterization of alkaline and oxidative stressed degradation products of lurasidone using LC/ESI/QTOF/MS/MS.
Topics: Alkalies; Chromatography, High Pressure Liquid; Drug Stability; Hot Temperature; Hydrolysis; Isoindoles; Lurasidone Hydrochloride; Oxidation-Reduction; Photolysis; Psychotropic Drugs; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Thiazoles; Ultraviolet Rays | 2015 |
Real-world adherence assessment of lurasidone and other oral atypical antipsychotics among patients with schizophrenia: an administrative claims analysis.
Topics: Adult; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Female; Humans; Insurance Claim Review; Lurasidone Hydrochloride; Male; Medicaid; Medication Adherence; Middle Aged; Olanzapine; Piperazines; Quetiapine Fumarate; Risperidone; Schizophrenia; Thiazoles; United States | 2017 |
Self microemulsifying drug delivery system of lurasidone hydrochloride for enhanced oral bioavailability by lymphatic targeting: In vitro, Caco-2 cell line and in vivo evaluation.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Coumarins; Drug Delivery Systems; Emulsions; Female; Humans; Lipids; Lurasidone Hydrochloride; Permeability; Rats; Rats, Sprague-Dawley; Solubility; Surface-Active Agents; Suspensions; Thiazoles | 2019 |
Health Care Cost in Patients With Schizophrenia Treated With Brexpiprazole Versus Other Oral Atypical Antipsychotic Therapy.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Aripiprazole; Female; Health Care Costs; Hospitalization; Humans; Lurasidone Hydrochloride; Male; Medicaid; Medicare; Middle Aged; Olanzapine; Paliperidone Palmitate; Piperazines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Thiazoles; Thiophenes; United States | 2020 |
Association of C-reactive protein and metabolic risk with cognitive effects of lurasidone in patients with schizophrenia.
Topics: Antipsychotic Agents; C-Reactive Protein; Cognition; Double-Blind Method; Humans; Isoindoles; Lurasidone Hydrochloride; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Treatment Outcome | 2020 |