thiazoles has been researched along with lumacaftor in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Becq, F; Boinot, C; Ferru-Clément, R; Jollivet Souchet, M | 1 |
| Beekman, JM; de Winter-de Groot, KM; Dekkers, JF; Gogorza Gondra, RA; Janssens, HM; Kruisselbrink, E; van der Ent, CK; Vonk, AM | 1 |
| Bali, V; Bebok, Z; Guroji, P; Lazrak, A; Matalon, S | 1 |
| Arkel, M; Cichero, E; Damonte, G; Fossa, P; Galietta, LJV; Liessi, N; Millo, E; Paccagnella, M; Pedemonte, N; Pesce, E; Salis, A; Tasso, B; Tomati, V | 1 |
| Bear, CE; Casavola, V; Laselva, O; Molinski, S | 1 |
| Amico, G; Baroni, D; Brandas, C; Moran, O | 1 |
| Baroni, D; Brandas, C; Cichero, E; Ludovico, A; Millo, E; Moran, O; Parodi, A | 1 |
7 other study(ies) available for thiazoles and lumacaftor
| Article | Year |
|---|---|
Searching for combinations of small-molecule correctors to restore f508del-cystic fibrosis transmembrane conductance regulator function and processing.
Topics: 1-Deoxynojirimycin; Aminopyridines; Benzamides; Benzodioxoles; Cell Survival; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; HeLa Cells; Humans; Thiazoles | 2014 |
Optimal correction of distinct CFTR folding mutants in rectal cystic fibrosis organoids.
Topics: Aminopyridines; Benzodioxoles; Biopsy; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Homozygote; Humans; Mutation; Organoids; Protein Folding; Protein Transport; Rectum; Thiazoles; Treatment Outcome | 2016 |
Mechanistic Approaches to Improve Correction of the Most Common Disease-Causing Mutation in Cystic Fibrosis.
Topics: Aminophenols; Aminopyridines; Benzamides; Benzodioxoles; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Gene Expression Regulation; Half-Life; HEK293 Cells; Humans; Mutation; Quinolones; Thiazoles | 2016 |
Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.
Topics: Aminopyridines; Benzodioxoles; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Mutation; Quantitative Structure-Activity Relationship; Thiazoles | 2018 |
Correctors of the Major Cystic Fibrosis Mutant Interact through Membrane-Spanning Domains.
Topics: Aminopyridines; Benzamides; Benzodioxoles; Cell Line; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; HEK293 Cells; Humans; Mutation; Phenylalanine; Protein Structure, Tertiary; Thiazoles | 2018 |
Unravelling the Regions of Mutant F508del-CFTR More Susceptible to the Action of Four Cystic Fibrosis Correctors.
Topics: Aminopyridines; Benzamides; Benzodioxoles; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression Regulation; HEK293 Cells; Humans; Indoles; Mutant Proteins; Mutation; Quinazolines; Thiazoles | 2019 |
NBD2 Is Required for the Rescue of Mutant F508del CFTR by a Thiazole-Based Molecule: A Class II Corrector for the Multi-Drug Therapy of Cystic Fibrosis.
Topics: Aminopyridines; Benzodioxoles; Cell Membrane; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Gene Expression Regulation; HEK293 Cells; Humans; Mutant Proteins; Phenylalanine; Thiazoles | 2021 |