thiazoles has been researched along with levodopa in 99 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 19 (19.19) | 18.2507 |
2000's | 67 (67.68) | 29.6817 |
2010's | 13 (13.13) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fernandes, MH; Pestana, M; Soares-da-Silva, P | 1 |
Fernandes, MH; Soares-da-Silva, P | 1 |
Pestana, M; Soares-da-Silva, P | 1 |
Brannan, T; Prikhojan, A; Yahr, MD | 1 |
Fernandes, MH; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
Kołodziejczyk, K; Maj, J; Rogóz, Z; Skuza, G | 1 |
Carvey, PM; Ling, ZD; Pieri, S | 1 |
d'Agostini, F; Damsma, G; DaPrada, M; DeBoer, P; Heeringa, MJ | 1 |
Fernandez, HH; Friedman, JH | 1 |
Althaus, JS; Fici, GJ; VonVoigtlander, PF | 1 |
Carvey, PM; Ling, ZD; Robie, HC; Tong, CW | 1 |
Oertel, WH; Pinter, MM; Pogarell, O | 1 |
Bennett, JP; Piercey, MF | 1 |
Appel, SH; Jankovic, J; Le, W; Rowe, DB; Xie, W; Zou, L | 1 |
Galiano, ML; Grandas, F | 1 |
Arnold, G; Kupsch, A | 1 |
Phillips, P | 1 |
Weiner, WJ | 1 |
Montastruc, JL; Rascol, O; Senard, JM | 1 |
LeWitt, PA | 1 |
Clarke C, E; Clarke J, A; Speller J, M | 2 |
Anderson, WM; Gauger, L; Hauser, RA; Zesiewicz, TA | 1 |
Cassel, W; Krüger, HP; Möller, JC; Oertel, WH; Peter, JH; Stiasny, K | 1 |
Tanner, CM | 1 |
Hebenstreit, E; Pinter, MM; Rutgers, AW | 1 |
Sternon, J; Supiot, F; Zegers de Beyl, D | 1 |
Archer, T; Fredriksson, A; Palomo, T | 1 |
Agapito, C; Bhattacharya, KF; Chaudhuri, KR; Pal, S | 1 |
Guttman, M; Houle, S; Hussey, D; Kish, S; Stewart, D; Wilson, A | 1 |
Ball, J | 1 |
Diroma, C; Fraddosio, A; Iliceto, G; Lamberti, S; Moramarco, A; Palagano, G; Zenzola, A | 1 |
Etminan, M; Rochon, PA; Samii, A; Takkouche, B | 1 |
Adler, CH; Blasucci, L; Carvey, P; Caviness, JN; Chase, WM; Ferry, JJ; Goetz, CG; Kompoliti, K; Leibowitz, MT; Leurgans, S; Pincus, JH; Raman, R; Tan, E; Yones, LC | 1 |
Azizi, E; Ostad, SN; Partovi, M; Sadeghein, A | 1 |
Montgomery, EB | 2 |
Jennings, D; Marek, K; Seibyl, J | 1 |
Clarke, CE; Guttman, M | 1 |
Quattrone, A; Zappia, M | 1 |
Reichmann, H | 1 |
Berardelli, A; De Pandis, MF; Modugno, N; Ruggieri, S; Stocchi, F; Thomas, A; Vacca, L; Valente, M | 1 |
Bassi, A; Boffa, L; Brusa, L; Caramia, MD; Peppe, A; Pierantozzi, M; Ruggieri, S; Stanzione, P; Stefani, A | 1 |
MacMahon, DG | 1 |
Blackman, JA; Buck, ML; Conaway, MR; Patrick, PD | 1 |
Morrish, PK | 1 |
Bares, M; Dostál, V; Ehler, E; Fanfrdlová, Z; Fiedler, J; Klajblová, H; Kulist'ák, P; Rektor, I; Rektorová, I; Ressner, P; Svátová, J; Urbánek, K; Velísková, J | 1 |
Albin, RL; Desmond, TJ; Frey, KA; Kemmerer, ES; Kilbourn, MR | 1 |
Inzelberg, R; Nisipeanu, P; Schechtman, E | 1 |
Barone, P | 1 |
Lu, CS; Mok, V; Shan, DE; Tsoi, TH; Wong, KS; Yang, CC | 1 |
Krahn, M; Lang, A; Marras, C; Naglie, G; Tomlinson, G | 1 |
Jankovic, J; Le, W; Pan, T | 1 |
Connemann, BJ; Schönfeldt-Lecuona, C | 1 |
Kohno, Y; Takeuchi, S | 1 |
Oertel, WH; Stiasny-Kolster, K | 1 |
Alexander-Brown, B; Atassi, F; Barclay, L; Bennett, S; Berry, D; Biglan, K; Borchert, L; Brocht, A; Brown, D; Daigneault, S; DeAngelis, M; Dillon, S; Dobson, J; Evans, S; Factor, S; Fahn, S; Fontaine, D; Ford, B; Fussell, B; Hall, J; Hammerstad, J; Harrigan, M; Hodgeman, K; Holloway, RG; Hubble, J; Jankovic, J; Kamp, C; Kieburtz, K; Kurlan, R; Lang, A; LeWitt, P; Marek, K; McDermott, M; Miyasaki, J; Montgomery, A; Musch, B; O'Connell, C; Pahwa, R; Panisset, M; Pantella, C; Petsinger, G; Pfeiffer, B; Pfeiffer, R; Rainey, P; Rajput, A; Richard, K; Riley, D; Rodnitzky, R; Ross, T; Rost-Ruffner, E; Russell, DS; Seibyl, J; Shinaman, A; Shirley, T; Shoulson, I; Shults, C; Sime, E; Stacy, M; Standaert, D; Suchowersky, O; Sutherland, L; Tennis, M; Waters, C; Watts, A; Weeks, C; Weiner, W; Welsh, M; Wood, S; Wooten, F | 1 |
Grosset, D; Grosset, K; Macphee, G; Needleman, F | 1 |
Cassel, W; Haja, D; Körner, Y; Krüger, HP; Meindorfner, C; Möller, JC; Oertel, WH; Stiasny-Kolster, K | 1 |
Bara-Jimenez, W; Chase, TN; Dimitrova, T; Favit, A; Mouradian, MM; Sherzai, A | 1 |
Chen, SD; Chen, Y; Li, B; Liu, WG; Lu, GQ | 1 |
Kurlan, R | 1 |
Althoff, R; Jacobson, J; Martineau, RJ; Singh, A | 1 |
Goetz, CG; Poewe, W; Rascol, O; Sampaio, C | 1 |
Bernauer, E; Finsterer, J | 1 |
Bédard, PJ; Grégoire, L; Guidetti, P; Izzo, E; Rassoulpour, A; Samadi, P; Schwarcz, R | 1 |
Asanuma, M; Diaz-Corrales, FJ; Miyazaki, I; Ogawa, N; Shimizu, M; Tanaka, K | 1 |
Ahlskog, JE; Bower, JH; Josephs, KA; Klos, KJ; Matsumoto, JY | 1 |
Schapira, AH | 1 |
Dick, AW; Holloway, RG; Noyes, K | 1 |
Brown, LA; Doan, J; Pellis, SM; Suchowersky, O; Whishaw, IQ | 1 |
Bharmal, A; Lu, C; Suchowersky, O | 1 |
Cenci, MA; Danysz, W; Dekundy, A; Pietraszek, M; Schaefer, D | 1 |
Molnar, MZ; Mucsi, I; Novak, M | 1 |
Chigir', IP; Fedorova, NV | 1 |
Schindehütte, J; Trenkwalder, C | 1 |
Kanzato, N; Murao, H; Nishihira, T; Takara, H | 1 |
Baltazar, G; Duarte, EP; Saavedra, A | 1 |
Bédard, PJ; Di Paolo, T; Grégoire, L; Guidetti, P; Izzo, E; Rassoulpour, A; Samadi, P; Schwarcz, R | 1 |
Duggal, HS; Singh, I | 1 |
Jin, CM; Lee, JJ; Lee, MK; Lim, SC; Yang, YJ | 1 |
Danysz, W; Dekundy, A; Gravius, A; Morè, L; Nagel, J; Pietraszek, M | 1 |
Almeida-Paes, R; Fialho Monteiro, PC; Frases, S; Gutierrez-Galhardo, MC; Nosanchuk, JD; Zancopé-Oliveira, RM | 1 |
Di Paolo, T; Grégoire, L; Lévesque, D; Morissette, M; Ouattara, B; Rouillard, C; Samadi, P; Tamim, MK | 1 |
Di Paolo, T; Gasparini, F; Gomez-Mancilla, B; Grégoire, L; Morin, N | 1 |
Brotchie, JM; Fox, SH; Johnston, TH; McIldowie, MJ; Piggott, MJ | 1 |
Auguet, M; Chabrier, PE; Ferrandis, E; Grandoulier, AS; Marin, JG; Mautino, G; Rocher, MN; Spinnewyn, B | 1 |
Feng, LR; Maguire-Zeiss, KA | 1 |
Konitsiotis, S; Maranis, S; Stamatis, D; Tsironis, C | 1 |
Asanuma, M; Kikkawa, Y; Kimoto, N; Miyazaki, I; Miyoshi, K; Murakami, S; Takeshima, M | 1 |
Gomperts, SN; Growdon, JH; Johnson, KA; Locascio, JJ; Marquie, M; Maye, J; Rentz, DM; Santarlasci, AL | 1 |
Aron Badin, R; Auguet, M; Bertrand, A; Boulet, S; Brouillet, E; Chabrier, PE; Dollé, F; Gaillard, MC; Guillermier, M; Hantraye, P; Jan, C; Malgorn, C; Savasta, M; Spinnewyn, B; Van Camp, N | 1 |
Di Paolo, T; Morissette, M; Parent, M; Riahi, G; Samadi, P | 1 |
Bimpisidis, Z; Cenci, MA; Iderberg, H; Rylander, D | 1 |
Fujita, M; Hagino, Y; Hashimoto, M; Ikeda, K; Kasai, S; Kobayashi, K; Meltzer, HY; Setogawa, S; Yamaura, H; Yanagihara, D | 1 |
Ali, F; Josephs, KA | 1 |
20 review(s) available for thiazoles and levodopa
Article | Year |
---|---|
Pramipexole--a new dopamine agonist for the treatment of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Benzothiazoles; Dopamine Agonists; Humans; Levodopa; Motor Activity; Parkinson Disease; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Thiazoles | 1999 |
[Pramipexol: a new dopaminergic agonist for the treatment of Parkinson disease].
Topics: Benzothiazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Levodopa; Parkinson Disease; Pramipexole; Prospective Studies; Thiazoles; Treatment Outcome | 1999 |
The initial treatment of Parkinson's disease should begin with levodopa.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Bromocriptine; Drug Therapy, Combination; Essential Tremor; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Receptors, Dopamine; Thiazoles; Time Factors | 1999 |
Treatment of Parkinson's disease should begin with a dopamine agonist.
Topics: Benzothiazoles; Bromocriptine; Cabergoline; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ergolines; Humans; Indoles; Levodopa; Lisuride; Parkinson Disease; Pergolide; Pramipexole; Receptors, Dopamine D2; Thiazoles | 1999 |
New drugs for the treatment of Parkinson's disease.
Topics: Antiparkinson Agents; Benzophenones; Benzothiazoles; Cabergoline; Catechol O-Methyltransferase Inhibitors; Dopamine Agonists; Drug Synergism; Enzyme Inhibitors; Ergolines; Humans; Indoles; Levodopa; Nitrophenols; Parkinson Disease; Pramipexole; Thiazoles; Tolcapone | 2000 |
Pramipexole versus bromocriptine for levodopa-induced complications in Parkinson's disease.
Topics: Antiparkinson Agents; Benzothiazoles; Bromocriptine; Dopamine Agonists; Drug Tolerance; Humans; Levodopa; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Thiazoles | 2000 |
Pramipexole for levodopa-induced complications in Parkinson's disease.
Topics: Antiparkinson Agents; Benzothiazoles; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Dopamine Agonists; Humans; Levodopa; Pramipexole; Randomized Controlled Trials as Topic; Thiazoles | 2000 |
["Sleep attacks" in Parkinson patients. A side effect of nonergoline dopamine agonists or a class effect of dopamine agonists?].
Topics: Accidents, Traffic; Automobile Driving; Benzothiazoles; Contraindications; Dopamine Agents; Dopamine Agonists; Germany; Humans; Indoles; Legislation, Drug; Levodopa; Narcolepsy; Parkinson Disease; Pramipexole; Thiazoles | 2000 |
Increased risk of somnolence with the new dopamine agonists in patients with Parkinson's disease: a meta-analysis of randomised controlled trials.
Topics: Antiparkinson Agents; Benzothiazoles; Disorders of Excessive Somnolence; Dopamine Agonists; Drug Therapy, Combination; Humans; Indoles; Levodopa; MEDLINE; Parkinson Disease; Pramipexole; Randomized Controlled Trials as Topic; Risk Factors; Thiazoles | 2001 |
Two advances in the management of Parkinson disease.
Topics: Age Factors; Antiparkinson Agents; Benzothiazoles; Carbidopa; Dyskinesias; Electric Stimulation Therapy; Forecasting; Humans; Indoles; Levodopa; Parkinson Disease; Pramipexole; Risk Factors; Stereotaxic Techniques; Thiazoles | 2002 |
DA agonists -- non-ergot derivatives: pramipexole: management of Parkinson's disease.
Topics: Benzothiazoles; Dopamine Agonists; Humans; Levodopa; Parkinson Disease; Pramipexole; Psychomotor Disorders; Randomized Controlled Trials as Topic; Thiazoles | 2002 |
Do dopamine agonists or levodopa modify Parkinson's disease progression?
Topics: Animals; Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Dihydroxyphenylalanine; Disease Progression; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; Indoles; Iodine Radioisotopes; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Tropanes | 2002 |
Dopamine agonist monotherapy in Parkinson's disease.
Topics: Benzothiazoles; Cabergoline; Dopamine Agonists; Ergolines; Humans; Indoles; Levodopa; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Randomized Controlled Trials as Topic; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2002 |
Neuroprotection in idiopathic Parkinson's disease.
Topics: Antiparkinson Agents; Benzothiazoles; Cell Death; Dopamine Agonists; Humans; Indoles; Levodopa; Neuroprotective Agents; Parkinson Disease; Pramipexole; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2002 |
Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: an evidence-based comparison.
Topics: Age of Onset; Benzothiazoles; Cabergoline; Dopamine Agonists; Double-Blind Method; Ergolines; Evidence-Based Medicine; Humans; Indoles; Levodopa; Parkinson Disease; Pramipexole; Thiazoles | 2003 |
Clinical strategies to prevent and delay motor complications.
Topics: Antiparkinson Agents; Benzothiazoles; Dopamine Agonists; Dyskinesia, Drug-Induced; Humans; Levodopa; Parkinson Disease; Pramipexole; Thiazoles | 2003 |
[Pharmacological profiles and clinical effects of antiparkinsonian agent, pramipexole].
Topics: Animals; Antiparkinson Agents; Benzothiazoles; Dopamine Agonists; Drug Therapy, Combination; Humans; Levodopa; Neuroprotective Agents; Parkinson Disease; Pramipexole; Thiazoles | 2004 |
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.
Topics: Amantadine; Antiparkinson Agents; Apomorphine; Benzophenones; Benzothiazoles; Bromocriptine; Cabergoline; Catechol O-Methyltransferase Inhibitors; Deep Brain Stimulation; Dihydroergocryptine; Ergolines; Fetal Tissue Transplantation; Globus Pallidus; Humans; Indans; Indoles; Levodopa; Lisuride; Mesencephalon; Monoamine Oxidase Inhibitors; Neurosurgical Procedures; Nitrophenols; Parkinson Disease; Pergolide; Piribedil; Pramipexole; Selegiline; Thiazoles; Tolcapone | 2005 |
Present and future drug treatment for Parkinson's disease.
Topics: Benzothiazoles; Corpus Striatum; Disease Progression; Dopamine Agonists; Drug Therapy, Combination; Humans; Indans; Indoles; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Pramipexole; Psychomotor Performance; Sexual Dysfunction, Physiological; Sleep Wake Disorders; Substantia Nigra; Thiazoles; Urinary Incontinence | 2005 |
Management of restless legs syndrome in patients on dialysis.
Topics: Amines; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Narcotics; Pramipexole; Renal Dialysis; Restless Legs Syndrome; Thiazoles; Uremia | 2006 |
19 trial(s) available for thiazoles and levodopa
Article | Year |
---|---|
Efficacy, safety, and tolerance of the non-ergoline dopamine agonist pramipexole in the treatment of advanced Parkinson's disease: a double blind, placebo controlled, randomised, multicentre study.
Topics: Adult; Aged; Antiparkinson Agents; Benzothiazoles; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Pramipexole; Prospective Studies; Thiazoles | 1999 |
[Pramipexol: a new dopaminergic agonist for the treatment of Parkinson disease].
Topics: Benzothiazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Levodopa; Parkinson Disease; Pramipexole; Prospective Studies; Thiazoles; Treatment Outcome | 1999 |
Pramipexole-induced somnolence and episodes of daytime sleep.
Topics: Aged; Antiparkinson Agents; Automobile Driving; Benzothiazoles; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Middle Aged; Narcolepsy; Parkinson Disease; Polysomnography; Pramipexole; Retrospective Studies; Thiazoles | 2000 |
Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.
Topics: Antiparkinson Agents; Benzothiazoles; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Double-Blind Method; Dyskinesias; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Proportional Hazards Models; Quality of Life; Radiopharmaceuticals; Thiazoles; Tomography, Emission-Computed, Single-Photon | 2000 |
An open-label, multicentre clinical trial to determine the levodopa dose-sparing capacity of pramipexole in patients with idiopathic Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Prospective Studies; Thiazoles; Treatment Outcome | 2000 |
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain Chemistry; Carbon Radioisotopes; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Receptors, Dopamine; Thiazoles; Tomography, Emission-Computed | 2001 |
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Brain; Cocaine; Disease Progression; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Parkinson Disease; Pramipexole; Radiopharmaceuticals; Randomized Controlled Trials as Topic; Regression Analysis; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2002 |
Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics.
Topics: Aged; Antiparkinson Agents; Area Under Curve; Benzothiazoles; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Humans; Levodopa; Male; Parkinson Disease; Postmenopause; Pramipexole; Sex Factors; Thiazoles | 2002 |
Combination of two different dopamine agonists in the management of Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Cabergoline; Dopamine Agonists; Drug Therapy, Combination; Ergolines; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Prospective Studies; Thiazoles; Treatment Outcome | 2002 |
Pramipexole in comparison to l-dopa: a neuropsychological study.
Topics: Aged; Analysis of Variance; Benzothiazoles; Cognition Disorders; Female; Humans; Levodopa; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Pramipexole; Thiazoles | 2003 |
Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study.
Topics: Activities of Daily Living; Aged; Analysis of Variance; Antiparkinson Agents; Benzothiazoles; Cross-Over Studies; Depression; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Motor Activity; Parkinson Disease; Pergolide; Placebos; Pramipexole; Prospective Studies; Psychiatric Status Rating Scales; Severity of Illness Index; Single-Blind Method; Thiazoles; Treatment Outcome | 2003 |
Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: an evidence-based comparison.
Topics: Age of Onset; Benzothiazoles; Cabergoline; Dopamine Agonists; Double-Blind Method; Ergolines; Evidence-Based Medicine; Humans; Indoles; Levodopa; Parkinson Disease; Pramipexole; Thiazoles | 2003 |
Efficacy, safety, and tolerability of pramipexole in untreated and levodopa-treated patients with Parkinson's disease.
Topics: Adult; Benzothiazoles; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Female; Hong Kong; Humans; Levodopa; Male; Parkinson Disease; Pramipexole; Software Design; Taiwan; Thiazoles; Treatment Outcome | 2003 |
Quality of life in early Parkinson's disease: impact of dyskinesias and motor fluctuations.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Carbidopa; Double-Blind Method; Drug Combinations; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Pain Measurement; Parkinson Disease; Pramipexole; Quality of Life; Thiazoles | 2004 |
Low-dose pramipexole in the management of restless legs syndrome. An open label trial.
Topics: Administration, Oral; Aged; Antiparkinson Agents; Benzothiazoles; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Levodopa; Male; Middle Aged; Polysomnography; Pramipexole; Restless Legs Syndrome; Severity of Illness Index; Sleep Wake Disorders; Thiazoles; Treatment Outcome | 2004 |
Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.
Topics: Aged; Benzothiazoles; Double-Blind Method; Female; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Proportional Hazards Models; Quality of Life; Severity of Illness Index; Thiazoles | 2004 |
Effect of monoamine reuptake inhibitor NS 2330 in advanced Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Carbidopa; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Indoles; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Pilot Projects; Pramipexole; Thiazoles | 2004 |
Pramipexole and levodopa in early Parkinson's disease: dynamic changes in cost effectiveness.
Topics: Administration, Oral; Adult; Antiparkinson Agents; Benzothiazoles; Cost-Benefit Analysis; Double-Blind Method; Female; Health Expenditures; Humans; Levodopa; Male; Parkinson Disease; Pramipexole; Prospective Studies; Reproducibility of Results; Sex Factors; Thiazoles; Time Factors; Treatment Outcome | 2005 |
Motor deficits in Parkinsonian reaching: dopa-sensitivity influenced by real-world task constraint.
Topics: Activities of Daily Living; Aged; Amantadine; Antiparkinson Agents; Arm; Benzothiazoles; Biomechanical Phenomena; Carbidopa; Catechols; Dopamine Agents; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Motor Skills; Movement; Nitriles; Parkinson Disease; Pramipexole; Thiazoles | 2006 |
62 other study(ies) available for thiazoles and levodopa
Article | Year |
---|---|
Deamination of newly-formed dopamine in rat renal tissues.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Deamination; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Pargyline; Picolinic Acids; Rats; Rats, Wistar; Thiazoles | 1991 |
Role of monoamine oxidase A and B in the deamination of newly-formed dopamine in the rat kidney.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Deamination; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Picolinic Acids; Rats; Rats, Inbred Strains; Thiazoles | 1990 |
Effect of type A and B monoamine oxidase selective inhibition by Ro 41-1049 and Ro 19-6327 on dopamine outflow in rat kidney slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Dopamine; In Vitro Techniques; Isoenzymes; Kidney Cortex; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Picolinic Acids; Rats; Rats, Wistar; Thiazoles | 1994 |
Effect of a selective MAO-A inhibitor (Ro 41-1049) on striatal L-dopa and dopamine metabolism: an in vivo study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catechols; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Levodopa; Male; Monoamine Oxidase Inhibitors; Rats; Rats, Sprague-Dawley; Thiazoles | 1994 |
In vivo effects of the monoamine oxidase inhibitors Ro 41-1049 and Ro 19-6327 on the production and fate of renal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Kidney; Levodopa; Male; Monoamine Oxidase Inhibitors; Picolinic Acids; Rats; Rats, Wistar; Thiazoles; Tissue Distribution | 1994 |
The behavioural effects of pramipexole, a novel dopamine receptor agonist.
Topics: Animals; Antiparkinson Agents; Benzazepines; Benzothiazoles; Body Temperature; Catalepsy; Clozapine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Haloperidol; Injections, Subcutaneous; Levodopa; Male; Mice; Motor Activity; Pramipexole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Stereotyped Behavior; Sulpiride; Thiazoles | 1997 |
Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole.
Topics: Animals; Antiparkinson Agents; Benzothiazoles; Cell Count; Cell Survival; Culture Media, Conditioned; Dopamine Agonists; Female; Immunohistochemistry; Levodopa; Mesencephalon; Neurons; Pramipexole; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thiazoles; Tyrosine 3-Monooxygenase | 1997 |
Effect of monoamine oxidase A and B and of catechol-O-methyltransferase inhibition on L-DOPA-induced circling behavior.
Topics: Animals; Antiparkinson Agents; Benzophenones; Catechol O-Methyltransferase Inhibitors; Enzyme Inhibitors; Levodopa; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nitrophenols; Oxidopamine; Picolinic Acids; Rats; Rotation; Thiazoles; Tolcapone | 1997 |
New anti-parkinsonian drugs.
Topics: Antiparkinson Agents; Benzophenones; Benzothiazoles; Humans; Indoles; Levodopa; Nitrophenols; Parkinson Disease; Pramipexole; Thiazoles; Tolcapone | 1998 |
Pharmacological approaches to counter the toxicity of Dopa.
Topics: Animals; Benzothiazoles; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Glutathione; Levodopa; Neuroprotective Agents; Pramipexole; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Selegiline; Thiazoles; Vitamin E | 1998 |
Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures.
Topics: Animals; Antioxidants; Benzothiazoles; Cell Count; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Dopamine Agents; Dopamine Agonists; Levodopa; Mesencephalon; Neuroprotective Agents; Pramipexole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Thiazoles; Tyrosine 3-Monooxygenase; Vitamin E | 1999 |
Neuroprotection by pramipexole against dopamine- and levodopa-induced cytotoxicity.
Topics: Animals; Benzothiazoles; Cell Line; Cell Survival; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Kinetics; Levodopa; Neuroblastoma; Neuroprotective Agents; Pramipexole; Thiazoles | 1999 |
[High dosage therapy of Parkinson disease. New dopamine agonist pramipexol allows reduction of L-dopa dose down to zero].
Topics: Antiparkinson Agents; Benzothiazoles; Carbidopa; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Pramipexole; Thiazoles | 1999 |
Several classes of new drugs emerging for Parkinson disease.
Topics: Antiparkinson Agents; Benzothiazoles; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine Agonists; Enzyme Inhibitors; Humans; Indoles; Levodopa; Nitriles; Parkinson Disease; Pramipexole; Thiazoles | 1999 |
Dopamine agonists in early therapy for Parkinson disease: promise and problems.
Topics: Antiparkinson Agents; Benzothiazoles; Dopamine Agonists; Humans; Levodopa; Parkinson Disease; Pramipexole; Thiazoles | 2000 |
[Dopaminergic agonists in the treatment of Parkinson's disease].
Topics: Aged; Antiparkinson Agents; Apomorphine; Benzothiazoles; Biological Availability; Bromocriptine; Catechols; Dopamine Agonists; Drug Combinations; Drug Hypersensitivity; Humans; Hypotension, Orthostatic; Indoles; Levodopa; Metabolic Clearance Rate; Nitriles; Parkinson Disease; Pergolide; Pramipexole; Selegiline; Thiazoles | 2000 |
Effects of MAO inhibitors upon MPTP mice chronically treated with suprathreshold doses of L-dopa.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Clorgyline; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Levodopa; Locomotion; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Phenelzine; Phenethylamines; Selegiline; Thiazoles; Tryptamines | 2000 |
A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Benzothiazoles; Cabergoline; Disorders of Excessive Somnolence; Drug Therapy, Combination; Ergolines; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Retrospective Studies; Thiazoles | 2001 |
Current advances in Parkinson's disease.
Topics: Antidepressive Agents; Antiparkinson Agents; Benzothiazoles; Brain Stem; Catechols; Depression; Dopamine Agonists; Humans; Levodopa; Nitriles; Parkinson Disease; Pramipexole; Selegiline; Thiazoles | 2001 |
Efficacy and tolerability of dopamine agonists in a parkinsonian population.
Topics: Age of Onset; Aged; Aging; Benzothiazoles; Bromocriptine; Dopamine Agonists; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Ergolines; Female; Follow-Up Studies; Humans; Indoles; Levodopa; Lisuride; Male; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Retrospective Studies; Thiazoles; Treatment Outcome | 2001 |
Mitogenic effect of L-dopa on human periodontal ligament fibroblast cells.
Topics: Cells, Cultured; Coloring Agents; Dopamine Agents; Fibroblasts; Humans; Levodopa; Mitosis; Periodontal Ligament; Tetrazolium Salts; Thiazoles; Tissue Preservation | 2002 |
Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics.
Topics: Antiparkinson Agents; Area Under Curve; Benzothiazoles; Biological Availability; Body Weight; Drug Interactions; Female; Humans; Levodopa; Male; Pramipexole; Sex Characteristics; Thiazoles | 2002 |
The initial drug treatment of older patients with Parkinson's disease - consider an agonist, but don't demonise dopa.
Topics: Antiparkinson Agents; Benzothiazoles; Catechol O-Methyltransferase; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Indoles; Levodopa; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Thiazoles | 2003 |
The use of dopamine enhancing medications with children in low response states following brain injury.
Topics: Adolescent; Adult; Amantadine; Arousal; Awareness; Benzothiazoles; Brain Injuries; Bromocriptine; Child; Dopamine Agents; Dopamine Agonists; Female; Humans; Levodopa; Male; Methylphenidate; Neuropsychological Tests; Pramipexole; Retrospective Studies; Thiazoles; Treatment Outcome; Unconsciousness | 2003 |
REAL and CALM: what have we learned?
Topics: Antiparkinson Agents; Benzothiazoles; Clinical Trials as Topic; Corpus Striatum; Disease Progression; Dopamine; Feasibility Studies; Humans; Indoles; Levodopa; Neurons; Neuroprotective Agents; Parkinson Disease; Pramipexole; Putamen; Reference Values; Sensitivity and Specificity; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon | 2003 |
Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole.
Topics: Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Autoradiography; Behavior, Animal; Benzothiazoles; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Neuropeptides; Oxidopamine; Parkinsonian Disorders; Pramipexole; Rats; Rats, Sprague-Dawley; Substantia Nigra; Thiazoles; Treatment Outcome; Tritium; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2003 |
Slowing Parkinson's disease progression: recent dopamine agonist trials.
Topics: Antiparkinson Agents; Artifacts; Benzothiazoles; Clinical Trials as Topic; Disease Progression; Dopamine Agonists; Humans; Levodopa; Parkinson Disease; Pramipexole; Severity of Illness Index; Single-Blind Method; Thiazoles | 2004 |
Slowing Parkinson's disease progression: recent dopamine agonist trials.
Topics: Antiparkinson Agents; Benzothiazoles; Biological Transport; Cell Line, Tumor; Clinical Trials as Topic; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Humans; In Vitro Techniques; Indoles; Levodopa; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroblastoma; Parkinson Disease; Pramipexole; Thiazoles | 2004 |
Ziprasidone in Parkinson's disease psychosis.
Topics: Aged; Antipsychotic Agents; Dopamine Agonists; Humans; Levodopa; Male; Parkinson Disease; Piperazines; Psychoses, Substance-Induced; Thiazoles | 2004 |
Switching from ergot to nonergot dopamine agonists in Parkinson's disease: a clinical series and five-drug dose conversion table.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Antiparkinson Agents; Benzothiazoles; Bromocriptine; Cabergoline; Domperidone; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ergolines; Ergot Alkaloids; Feasibility Studies; Female; Follow-Up Studies; Humans; Indoles; Levodopa; Male; Middle Aged; Parkinson Disease; Pergolide; Pramipexole; Therapeutic Equivalency; Thiazoles | 2004 |
Predictors of sudden onset of sleep in Parkinson's disease.
Topics: Aged; Antiparkinson Agents; Benzothiazoles; Comorbidity; Cross-Sectional Studies; Dopamine Agonists; Drug Therapy, Combination; Ergolines; Female; Humans; Indoles; Levodopa; Male; Middle Aged; Narcolepsy; Parkinson Disease; Pramipexole; Risk Factors; Surveys and Questionnaires; Thiazoles | 2004 |
Neuroprotection by pergolide against levodopa-induced cytotoxicity of neural stem cells.
Topics: Animals; Annexin A5; Antimetabolites; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cells, Cultured; Dopamine Agents; Flow Cytometry; Fluorescein-5-isothiocyanate; Levodopa; Mice; Neurons; Neuroprotective Agents; Pergolide; Stem Cells; Tetrazolium Salts; Thiazoles | 2004 |
"Levodopa phobia": a new iatrogenic cause of disability in Parkinson disease.
Topics: Aged; Amantadine; Benzothiazoles; Catechols; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Humans; Iatrogenic Disease; Indoles; Levodopa; Male; Middle Aged; Neurology; Neuropharmacology; Neurotoxicity Syndromes; Nitriles; Parkinson Disease; Pramipexole; Selegiline; Thiazoles; Treatment Outcome | 2005 |
Pramipexole, ropinirole, and mania in Parkinson's disease.
Topics: Adult; Antiparkinson Agents; Benzothiazoles; Bipolar Disorder; Dopamine Agonists; Drug Therapy, Combination; Female; Humans; Indoles; Levodopa; Parkinson Disease; Pramipexole; Thiazoles | 2005 |
Recovery from parkinson syndrome and prolonged visually evoked potentials in hepatic encephalopathy.
Topics: Anti-Bacterial Agents; Antiparkinson Agents; Benzothiazoles; Brain; Chronic Disease; Dipeptides; Evoked Potentials, Visual; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Levodopa; Male; Middle Aged; Parkinsonian Disorders; Paromomycin; Pramipexole; Recovery of Function; Thiazoles; Treatment Outcome; Vision Disorders | 2005 |
Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Female; Kynurenic Acid; Kynurenine 3-Monooxygenase; Levodopa; Macaca fascicularis; Mixed Function Oxygenases; Motor Activity; Parkinsonian Disorders; Quinolinic Acid; Sulfonamides; Thiazoles; Time Factors | 2005 |
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antiparkinson Agents; Benzoquinones; Benzothiazoles; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Electron Spin Resonance Spectroscopy; Functional Laterality; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred ICR; Oxidopamine; Parkinson Disease; Pramipexole; Thiazoles; Time Factors | 2005 |
Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy.
Topics: Adult; Aged; Antiparkinson Agents; Benzothiazoles; Catechols; Databases, Factual; Dopamine Agonists; Humans; Indoles; Levodopa; Male; Mental Disorders; Middle Aged; Multiple System Atrophy; Nitriles; Parkinson Disease; Pramipexole; Sexual Dysfunctions, Psychological; Thiazoles | 2005 |
Gambling and Parkinson disease.
Topics: Antiparkinson Agents; Benzothiazoles; Gambling; Humans; Levodopa; Parkinson Disease; Pramipexole; Risk Factors; Thiazoles | 2006 |
Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Behavior, Animal; Catalepsy; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesias; Functional Laterality; Haloperidol; Levodopa; Male; Motor Activity; Oxidopamine; Parkinson Disease; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Rotarod Performance Test; Thiazoles; Time Factors | 2006 |
[Dopamine receptors agonists (mirapex) in the treatment of Parkinson's disease].
Topics: Anxiety; Benzothiazoles; Carbidopa; Delayed-Action Preparations; Depression; Dopamine Agonists; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Pramipexole; Receptors, Dopamine D1; Thiazoles; Treatment Outcome | 2006 |
Treatment of drug-induced psychosis in Parkinson's disease with ziprasidone can induce severe dose-dependent off-periods and pathological laughing.
Topics: Aged; Antiparkinson Agents; Antipsychotic Agents; Clozapine; Dibenzothiazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Laughter; Levodopa; Male; Middle Aged; Neurologic Examination; Parkinson Disease; Parkinson Disease, Secondary; Piperazines; Psychoses, Substance-Induced; Quetiapine Fumarate; Thiazoles | 2007 |
[Case of juvenile parkinsonism in pregnancy].
Topics: Adult; Antiparkinson Agents; Benzothiazoles; Cabergoline; Carbidopa; Contraindications; Dopamine Agents; Dopamine Agonists; Ergolines; Family Planning Services; Female; Humans; Infant, Newborn; Levodopa; Parkinsonian Disorders; Pramipexole; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Thiazoles | 2006 |
Interleukin-1beta mediates GDNF up-regulation upon dopaminergic injury in ventral midbrain cell cultures.
Topics: Animals; Astrocytes; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Dopamine; Dopamine Agents; Enzyme-Linked Immunosorbent Assay; Glial Cell Line-Derived Neurotrophic Factor; Glial Fibrillary Acidic Protein; Hydrogen Peroxide; Immunohistochemistry; Interleukin-1beta; Levodopa; Mesencephalon; Neuroglia; Oxidants; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Up-Regulation; Ventral Tegmental Area | 2007 |
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Disease Models, Animal; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Female; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Levodopa; Macaca fascicularis; Motor Activity; Parkinsonian Disorders; Quinolinic Acid; Sulfonamides; Thiazoles; Time Factors | 2008 |
Ziprasidone for drug-induced psychotic symptoms in Parkinson's Disease.
Topics: Acute Disease; Antipsychotic Agents; Brief Psychiatric Rating Scale; Carbidopa; Drug Combinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Piperazines; Psychoses, Substance-Induced; Thiazoles | 2008 |
Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells.
Topics: Animals; Antiparkinson Agents; Apoptosis; Aromatic-L-Amino-Acid Decarboxylases; Blotting, Northern; Calcium; Carbolines; Cell Survival; Cyclic AMP; Dopamine; Flow Cytometry; Harmine; In Situ Nick-End Labeling; Levodopa; Membrane Potentials; Mitochondrial Membranes; PC12 Cells; Rats; RNA; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2008 |
Investigation on tolerance development to subchronic blockade of mGluR5 in models of learning, anxiety, and levodopa-induced dyskinesia in rats.
Topics: Animals; Antiparkinson Agents; Anxiety Disorders; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Glutamic Acid; Learning Disabilities; Levodopa; Male; Maze Learning; Memory Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thiazoles | 2008 |
Growth conditions influence melanization of Brazilian clinical Sporothrix schenckii isolates.
Topics: Brazil; Culture Media; Hydrogen-Ion Concentration; Hyphae; Levodopa; Melanins; Naphthols; Pigments, Biological; Sporothrix; Temperature; Thiazoles; Time Factors | 2009 |
Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: common implication of striatal neuropeptides.
Topics: Animals; Antiparkinson Agents; Benzoxazoles; Cocaine; Corpus Striatum; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Dopamine Uptake Inhibitors; Dynorphins; Dyskinesia, Drug-Induced; Enkephalins; Female; Iodine Isotopes; Levodopa; Macaca fascicularis; Naltrexone; Neuropeptides; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Precursors; RNA, Messenger; Sulfonamides; Tachykinins; Thiazoles; Time Factors | 2010 |
Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys.
Topics: Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Levodopa; Locomotion; Macaca fascicularis; Parkinsonian Disorders; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Severity of Illness Index; Thiazoles; Time Factors; Treatment Outcome | 2010 |
Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Male; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Piperidines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2010 |
BN82451 attenuates L-dopa-induced dyskinesia in 6-OHDA-lesioned rat model of Parkinson's disease.
Topics: Animals; Area Under Curve; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Gene Expression; Levodopa; Male; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles | 2011 |
Dopamine and paraquat enhance α-synuclein-induced alterations in membrane conductance.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Cell Line, Tumor; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Doxycycline; Drug Interactions; Gene Expression Regulation; Green Fluorescent Proteins; Heme Oxygenase-1; Herbicides; Humans; Levodopa; Membrane Potentials; Mice; Nerve Tissue Proteins; Neuroblastoma; Paraquat; Patch-Clamp Techniques; Permeability; Tetrazolium Salts; Thiazoles; Transfection; Tubulin; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2011 |
Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Infusions, Intraventricular; Levodopa; Male; Oxidopamine; Phenols; Piperidines; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus; Thiazoles | 2012 |
Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dopamine Agents; Dopaminergic Neurons; Glutathione; Indomethacin; Levodopa; Meloxicam; Methyldopa; Mice; Neurons; Neuroprotective Agents; Quinones; Sympatholytics; Thiazines; Thiazoles | 2012 |
Brain amyloid and cognition in Lewy body diseases.
Topics: Aged; Amyloid beta-Peptides; Aniline Compounds; Antiparkinson Agents; Apolipoprotein E3; Cognition; Cognitive Dysfunction; Female; Genotype; Humans; Levodopa; Lewy Body Disease; Male; Neurologic Examination; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Thiazoles | 2012 |
IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Antioxidants; Antiparkinson Agents; Behavior, Animal; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Disease Models, Animal; Dopamine Agents; Dyskinesias; Immunohistochemistry; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Neurons; Oxidative Stress; Parkinson Disease; Positron-Emission Tomography; Thiazoles | 2013 |
Basal ganglia serotonin 1B receptors in parkinsonian monkeys with L-DOPA-induced dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Benzamides; Brain; Case-Control Studies; Dyskinesia, Drug-Induced; Levodopa; Macaca fascicularis; Parkinson Disease; Pyridines; Receptor, Serotonin, 5-HT1B; Serotonin; Sulfonamides; Thiazoles | 2013 |
Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: effects of combined treatment and possible mechanisms of action.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiparkinson Agents; Dopamine Agonists; Drug Synergism; Dyskinesia, Drug-Induced; Levodopa; Parkinsonian Disorders; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptors, Dopamine D1; Serotonin Receptor Agonists; Thiazoles | 2013 |
Involvement of cholinergic system in hyperactivity in dopamine-deficient mice.
Topics: Acetylcholine; Akathisia, Drug-Induced; Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Central Nervous System Stimulants; Choline O-Acetyltransferase; Clozapine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Extracellular Space; Haloperidol; Levodopa; Locomotion; Mice, Inbred C57BL; Piperazines; Psychomotor Agitation; Thiazoles | 2015 |
Corticobasal degeneration: key emerging issues.
Topics: Aniline Compounds; Basal Ganglia; Carbolines; Cerebral Cortex; Dopamine Agents; History, 20th Century; Humans; Levodopa; Neurodegenerative Diseases; Positron-Emission Tomography; Supranuclear Palsy, Progressive; Thiazoles | 2018 |