thiazoles has been researched along with kn 62 in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baraldi, PG; Bianchini, E; Gambari, R; Lambertini, E; Penolazzi, L; Piva, R; Romagnoli, R | 1 |
| Bradley, HJ; Browne, LE; Jiang, LH; Yang, W | 1 |
| Kanjanamekanant, K; Luckprom, P; Pavasant, P | 1 |
| Talbot, P; Weng, NJ | 1 |
| Bin Dayel, A; Evans, RJ; Schmid, R | 1 |
5 other study(ies) available for thiazoles and kn 62
| Article | Year |
|---|---|
N-Arylpiperazine modified analogues of the P2X7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acid Phosphatase; Apoptosis; Bone and Bones; Bone Diseases, Metabolic; Caspase 3; Caspases; Cell Nucleus; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-6; Isoenzymes; Models, Chemical; NF-kappa B; Osteoblasts; Osteoclasts; Piperazines; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2X7; Tartrate-Resistant Acid Phosphatase; Tetrazolium Salts; Thiazoles; Time Factors | 2005 |
Pharmacological properties of the rhesus macaque monkey P2X7 receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Amino Acid Sequence; Animals; Benzoxazoles; HEK293 Cells; Humans; Macaca mulatta; Membrane Potentials; Molecular Sequence Data; Patch-Clamp Techniques; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridines; Quinolinium Compounds; Receptors, Purinergic P2X7; Single-Cell Analysis; Tetrazoles; Thiazoles | 2011 |
Mechanical stress-induced interleukin-1beta expression through adenosine triphosphate/P2X7 receptor activation in human periodontal ligament cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Adenosine Triphosphate; Apyrase; Benzenesulfonates; Calcium Channel Blockers; Calcium Signaling; Cell Culture Techniques; Cell Survival; Cells, Cultured; Coloring Agents; Dactinomycin; Homeostasis; Humans; Interleukin-1beta; Luminescent Measurements; Periodontal Ligament; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; RNA, Small Interfering; Signal Transduction; Stress, Mechanical; Suramin; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2013 |
The P2X7 receptor is an upstream regulator of dynamic blebbing and a pluripotency marker in human embryonic stem cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Biomarkers; Calcium; Cell Adhesion; Cell Differentiation; Cell Surface Extensions; Extracellular Space; Gene Knockdown Techniques; Human Embryonic Stem Cells; Humans; Ion Channel Gating; Models, Biological; Purinergic P2X Receptor Antagonists; rac GTP-Binding Proteins; Receptors, Purinergic P2X7; rho GTP-Binding Proteins; Thiazoles; Time-Lapse Imaging | 2017 |
Mapping the Site of Action of Human P2X7 Receptor Antagonists AZ11645373, Brilliant Blue G, KN-62, Calmidazolium, and ZINC58368839 to the Intersubunit Allosteric Pocket.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Site; Amides; Binding Sites; Humans; Imidazoles; Indoles; Models, Molecular; Molecular Docking Simulation; Point Mutation; Purinergic P2X Receptor Antagonists; Receptors, Purinergic P2X7; Rosaniline Dyes; Thiazoles | 2019 |