Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and khs101

thiazoles has been researched along with khs101 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Aimone, L; Chang, J; Charette, B; Cho, CY; Chopiuk, G; Cline, HT; Cravatt, BF; Demas, J; Halder, R; Lairson, LL; Min, KH; Peters, EC; Schultz, PG; Tuntland, T; Walker, JR; Watson, J; Weerapana, E; Wu, C; Wurdak, H; Zhang, J; Zhu, S1
Bruick, RK; Card, PB; Gardner, KH; Guo, Y; Key, J; Partch, CL; Pashkov, V; Patel, A; Wurdak, H1
Kibaly, C; Law, PY; Loh, HH; Xu, C; Zhang, Y1
Breuer, EK; Campo, L1
Abbosh, C; Allison, SJ; Ballereau, S; Beard, HA; Bon, RS; Chumas, P; Chuntharpursat-Bon, E; da Silva, B; Davies, AJ; Droop, A; Gestwicki, JE; Griffiths, HBS; Holding, AN; Kuchler, VB; Lorger, M; Markowetz, F; Mathew, RK; Patel, A; Polson, ES; Roberts, LD; Ross, EM; Shao, H; Short, SC; Williams, J; Wurdak, H; Zhu, S1
Cai, SZ; Ma, ZR; Shi, L; Sun, X; Zhao, W1

Other Studies

6 other study(ies) available for thiazoles and khs101

ArticleYear
A small molecule accelerates neuronal differentiation in the adult rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Sep-21, Volume: 107, Issue:38

    Topics: Adult Stem Cells; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Hippocampus; Male; Neurogenesis; Neurons; Phenotype; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; RNA, Messenger; Thiazoles

2010
Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.
    ACS chemical biology, 2013, Mar-15, Volume: 8, Issue:3

    Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Crystallography, X-Ray; HEK293 Cells; Humans; Microtubule-Associated Proteins; Models, Molecular; Protein Binding; Rats; Small Molecule Libraries; Structure-Activity Relationship; Thiazoles

2013
Temporal effect of manipulating NeuroD1 expression with the synthetic small molecule KHS101 on morphine contextual memory.
    Neuropharmacology, 2017, Volume: 126

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Conditioning, Classical; Extinction, Psychological; Hippocampus; Male; Memory; Mice, Inbred C57BL; Morphine; Narcotics; Neurogenesis; Thiazoles

2017
Inhibition of TACC3 by a small molecule inhibitor in breast cancer.
    Biochemical and biophysical research communications, 2018, 04-15, Volume: 498, Issue:4

    Topics: Apoptosis; Aurora Kinase A; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Microtubule-Associated Proteins; Neoplasm Proteins; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proteomics; Proto-Oncogene Proteins; Signal Transduction; Thiazoles

2018
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice.
    Science translational medicine, 2018, 08-15, Volume: 10, Issue:454

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chaperonin 60; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Glioblastoma; Glycolysis; Humans; Metabolic Networks and Pathways; Mitochondria; Mitochondrial Proteins; Neoplasm Invasiveness; Stress, Physiological; Survival Analysis; Thiazoles; Transcription, Genetic; Xenograft Model Antitumor Assays

2018
Discovery of novel analogs of KHS101 as transforming acidic coiled coil containing protein 3 (TACC3) inhibitors for the treatment of glioblastoma.
    European journal of medicinal chemistry, 2022, Dec-15, Volume: 244

    Topics: Cell Cycle Proteins; Glioblastoma; Humans; Microtubule-Associated Proteins; Thiazoles

2022