Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and jk184

thiazoles has been researched along with jk184 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, CY; Ding, S; Hebrok, M; Hong, J; Lee, J; Pasca di Magliano, M; Peters, EC; Schultz, PG; Wang, Y; Wu, X1
Chen, JK; Cupido, T; Firestone, AJ; Han, K; Hyman, JM; Ocasio, CA; Rack, PG; Sinha, S1
Colavito, SA; Nguyen, DX; Stern, DF; Yan, Q; Zou, MR1
Deng, S; Gong, C; Liu, L; Liu, S; Song, L; Su, W; Wang, N; Wei, Y; Wu, Q; Xie, Y; Zhang, N1
Addo, KA; Chdid, L; Darr, DB; Devi, GR; Ehe, BK; Fleming, JM; Ingram, SM; Oladapo, HO; Roques, JR; Sauer, SJ; Strepay, D; Tarpley, M; Trinkler, M; Williams, KP1

Other Studies

5 other study(ies) available for thiazoles and jk184

ArticleYear
A small-molecule antagonist of the hedgehog signaling pathway.
    Chembiochem : a European journal of chemical biology, 2007, Nov-05, Volume: 8, Issue:16

    Topics: Alcohol Dehydrogenase; Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gene Expression Regulation; Hedgehog Proteins; Heterocyclic Compounds, 2-Ring; Humans; Kruppel-Like Transcription Factors; Luciferases; Mesenchymal Stem Cells; Mice; Mice, Nude; Molecular Structure; Molecular Weight; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Thiazoles; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1

2007
The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:13

    Topics: Animals; Cell Line; Gene Expression Regulation, Developmental; Hedgehog Proteins; Heterocyclic Compounds, 2-Ring; Mice; Microtubules; NIH 3T3 Cells; Pyridines; Signal Transduction; Thiazoles

2009
Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.
    Breast cancer research : BCR, 2014, Sep-25, Volume: 16, Issue:5

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Claudins; Epithelial-Mesenchymal Transition; Female; Gene Expression; Heterocyclic Compounds, 2-Ring; Humans; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Receptor Cross-Talk; RNA, Messenger; Signal Transduction; Thiazoles; Transcription Factors; Zinc Finger Protein GLI1

2014
Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway.
    Nanoscale, 2015, Feb-14, Volume: 7, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biocompatible Materials; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatography, High Pressure Liquid; Drug Delivery Systems; Female; Hedgehog Proteins; Heterocyclic Compounds, 2-Ring; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Micelles; Nanomedicine; Neoplasm Transplantation; Neoplasms; Polymers; Signal Transduction; Thiazoles; Transgenes; Zebrafish

2015
Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.
    Cancer letters, 2017, 12-28, Volume: 411

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Heterocyclic Compounds, 2-Ring; Humans; Inflammatory Breast Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Pyridines; Pyrimidines; Signal Transduction; Thiazoles; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1

2017