Page last updated: 2024-08-21

thiazoles and isomethyleugenol

thiazoles has been researched along with isomethyleugenol in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19907 (11.29)18.7374
1990's8 (12.90)18.2507
2000's19 (30.65)29.6817
2010's26 (41.94)24.3611
2020's2 (3.23)2.80

Authors

AuthorsStudies
Ankenbauer, RG; Cox, CD; Rinehart, KL; Staley, AL1
Fujiwara, M; Kobayashi, T; Shibata, K; Takayanagi, N; Yamamoto, I1
Bakke, JE; Feil, VJ; Huwe, JK; Larsen, GL1
Davis, WM; Khalsa, JH1
Jackson, JR; Stoodley, RJ1
Fennessy, MR; Gaff, GA; Heimans, RL1
Nohta, H; Noma, S; Ohkura, Y; Yoo, BT1
Cundliffe, E; Thompson, J1
Bortolan-Gianese, P; Dubini, F; Falchi, M; Ferrario, F; Marcucci, A1
Belajová, E; Bujdáková, H; Farkas, P; Kuchta, T; Léka, C; Russell, NJ1
Andreani, A; Benelli, B; Degli Esposti, M; Ghelli, A; Leoni, A; Locatelli, A; Rambaldi, M; Ratta, M1
Iinuma, H; Naganawa, H; Shimanaka, K; Takahashi, Y; Takeuchi, T1
D'Souza, T; Dryer, SE; Nowak, JZ; Sek, B1
Horie, T; Kakiki, M; Kozaki, T; Mishima, M; Naitoh, T; Yuzuriha, T1
Agúndez, JA; Albet, C; Benítez, J; Carrillo, JA; Herrero, E; Márquez, M; Martínez, C; Ortiz, JA1
Kongkittingam, C; Vedejs, E1
Burke, RM; Doig, AJ; Hughes, E1
Blanchard, SG; Gribble, GW; Honda, T; Leesnitzer, LM; Mangelsdorf, DJ; Plunket, KD; Porter, WW; Sporn, MB; Suh, N; Wang, Y; Willson, TM1
Gordon, DJ; Meredith, SC; Sciarretta, KL1
Häring, HU; Kausch, C; Machicao, F; Rett, K; Stumvoll, M; Wahl, HG1
Gastaldo, L; Marinelli, F1
Tang, W; Yao, Y1
Aboul-ela, F; Klinck, R; Lentzen, G; Matassova, N; Murchie, AI1
Abdel Aleem, AH; Abdel-Aal, MT; El Ashry, ES; El-Sayed, WA1
Colwell, LF; Gonzalez, EJ; Habulihaz, B; He, H; Leiting, B; Lyons, KA; Marsilio, F; Ok, HO; Parmee, ER; Patel, RA; Thornberry, NA; Weber, AE; Wu, JK; Xu, J1
Gnirss, R; Jekel, M; Kloepfer, A; Reemtsma, T1
Boltze, C; Diab-Assef, M; Foltzer-Jourdainne, C; Gali-Muhtasib, H; Hartig, R; Roessner, A; Rohrbeck, A; Schneider-Stock, R; Schönfeld, P1
Badis, M; Gauthier-Manuel, B; Heck, R; Marsura, A; Rogalska, E; Van der Heyden, A; Zywocinski, A1
Berliner, MA; Clark, MP; Nag, PP; Stroup, BW; Williams, DR1
Berg, M; de la Nava, EM; Dodge, JA; Evers, B; Hankotius, D; Hary, U; Jungheim, LN; Mest, HJ; Mohr, M; Muehl, BS; Petersen, S; Riedel-Herold, G; Ruehter, G; Sommer, B; Tebbe, MJ; Thrasher, KJ; Voelkers, S1
Berscheit, HL; Huang, AJ; Yuan, C1
Bacskay, I; Feher, P; Fenyvesi, E; Fenyvesi, F; Kiss, T; Kocsan, R; Pasztor, N; Szabo, G; Szente, L; Varadi, J; Vecsernyes, M1
Charro, N; Florencio, MH; Justino, GC; Mira, L; Rodríguez-Gómez, MJ; Santos, MR1
Apirakaramwong, A; Kowapradit, J; Ngawhiranpat, T; Opanasopit, P; Rojanarata, T; Ruktanonchai, U; Sajomsang, W1
Chen, D; Gong, R; Jia, X; Li, Z; Murchie, AI; Shen, Y; Wang, P; Wang, Z; Xu, Y; Yang, H; Yang, Y; Zhao, L; Zhou, P1
Alioua, A; Berr, A; Heintz, D; Heitz, T; McCallum, EJ; Shen, WH1
Almy, J; de Revel, G; Marchand, S1
Gómez-Vallejo, V; Llop, J1
Barré, P; Eliezer, D; Huster, D; Künze, G; Scheidt, HA; Thomas, L1
Kamel, AM; Obach, RS; Prakash, C1
Boateng, AA; Nsimba, RY; West, N1
Gong, T; Jia, SJ; Lai, YQ; Zhang, BK; Zhao, M1
Lawrence, HR; Lawrence, NJ; Mahajan, K; Mahajan, NP1
Deng, K; Katz, L; Keasling, JD; Petzold, CJ; Phelan, RM; Poust, S1
Bagdi, AK; Ghosh, M; Hajra, A; Monir, K1
Attanzio, A; Barraja, P; Carbone, A; Ciancimino, C; Cirrincione, G; Di Vita, G; Diana, P; Livrea, MA; Montalbano, A; Parrino, B; Spanò, V; Tesoriere, L1
Chen, D; Jiang, H; Murchie, AI; Yin, S1
Bednarek, MA; Bockus, AT; Lokey, RS; Pye, CR; Schwochert, JA; Sok, V; Townsend, CE1
Chen, F; Gao, AH; Gong, CJ; Li, J; Li, JY; Nan, FJ; Sheng, L; Su, MB; Zhang, YM; Zhou, YB1
Beijnen, JH; Fox, JA; Jamieson, G; Lucas, L; Nijenhuis, CM; Rosing, H; Schellens, JH1
Cao, LL; Ji, J; Sun, XL; Yang, DD; Zeng, XN; Zhang, L; Zhao, Z1
Chen, F; Deng, Z; Ding, W; Ji, X; Li, Y; Mo, T; Qianzhu, H; Tu, T; Yu, Y; Zhang, Q; Zhao, J1
Harada, A; Komatsu, T; Kudou, K; Maehara, K; Maehara, Y; Nogami, J; Ohkawa, Y; Oki, E; Saeki, H1
Badding, ED; Booker, SJ; Gadsby, LK; Grove, TL; LaMattina, JW; Wang, B2
Brigaud, T; Chaume, G; Lensen, N; Miclet, E; Pytkowicz, J; Simon, J1
Hudson, GA; Mahanta, N; Mitchell, DA; van der Donk, WA; Zhang, Z1
Cantu, EJ; Forester, SC; Grimes, KL; Kaur, B; McCarthy, JJ; Stuart, CM1
Booker, SJ; Lamb, AL; McFarlane, JS; Prisinzano, TE; Ronnebaum, TA1
Jin, WB; Tang, GL; Wu, S; Xu, YF; Yuan, H1
Brigaud, T; Chaume, G; Lensen, N; Malquin, N; Miclet, E; Rahgoshay, K1
Cowling, VH; Fordyce, EAF; Gray, DW; Green, CJ; Pearson, LA; Petit, AP1

Reviews

1 review(s) available for thiazoles and isomethyleugenol

ArticleYear
Recent advances in HemN-like radical S-adenosyl-l-methionine enzyme-catalyzed reactions.
    Natural product reports, 2020, 01-01, Volume: 37, Issue:1

    Topics: Bacterial Proteins; Coproporphyrinogen Oxidase; Duocarmycins; Enzymes; Escherichia coli Proteins; Heme; Hydrogen; Methylation; Peptides, Cyclic; Polyketides; Protein Methyltransferases; S-Adenosylmethionine; Thiazoles

2020

Trials

1 trial(s) available for thiazoles and isomethyleugenol

ArticleYear
Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:4

    Topics: Adult; Anti-Anxiety Agents; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Benzenesulfonates; Caffeine; Central Nervous System Stimulants; Cimetidine; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dextromethorphan; Double-Blind Method; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Midazolam; Oxidoreductases, N-Demethylating; Psychomotor Performance; Ranitidine; Thiazoles

1999

Other Studies

60 other study(ies) available for thiazoles and isomethyleugenol

ArticleYear
Mutasynthesis of siderophore analogues by Pseudomonas aeruginosa.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-01, Volume: 88, Issue:5

    Topics: Indicators and Reagents; Iron; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Phenols; Pseudomonas aeruginosa; Spectrophotometry, Infrared; Structure-Activity Relationship; Thiazoles

1991
Immunomodulatory effect of a newly synthesized compound, TOK-8801 (N-(2-phenylethyl)-3,6,6-trimethyl-5,6-dihydroimidazo [2,1-b]thiazole-2-carboxamide) on antibody production in vivo and delayed-type hypersensitivity in mice.
    International journal of immunopharmacology, 1990, Volume: 12, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Antigens; Erythrocytes; Female; Humans; Hypersensitivity, Delayed; Imidazoles; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Serum Albumin; Sheep; Thiazoles

1990
In vitro metabolism of the methylthio group of 2-methylthiobenzothiazole by rat liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:3

    Topics: Animals; Benzothiazoles; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Gas Chromatography-Mass Spectrometry; Glutathione; Glutathione Transferase; In Vitro Techniques; Liver; Methylation; Oxidation-Reduction; Rats; Sulfhydryl Compounds; Thiazoles

1988
Morphine lethality in rats: effects of inhibitors of brain catecholamine synthesis and methylation.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:3

    Topics: Alcohols; Animals; Brain; Catechol O-Methyltransferase Inhibitors; Catecholamines; Cycloheptanes; Dopamine beta-Hydroxylase; Drug Synergism; Lethal Dose 50; Male; Methylation; Methyltyrosines; Morphine; Rats; Thiazoles; Thiourea; Time Factors; Tyrosine 3-Monooxygenase

1973
Studies related to penicillins. VII. The structure of the epimers derived from 6 -substituted penicillanic acids.
    Journal of the Chemical Society. Perkin transactions 1, 1972, Volume: 6

    Topics: Chemical Phenomena; Chemistry; Methylation; Nitriles; Penicillanic Acid; Penicillins; Stereoisomerism; Thiazoles

1972
Some aspects of the metabolism of morphine-N-oxide.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:11

    Topics: Acridines; Analgesics; Animals; Codeine; Cyclic N-Oxides; In Vitro Techniques; Injections, Intraperitoneal; Liver; Male; Methylation; Morphinans; Morphine; Rats; Thiazoles

1971
Assay for catechol-O-methyltransferase in erythrocytes using a new fluorogenic substrate, 2-(3,4-dihydroxyphenyl)naphtho[1,2-d]thiazole.
    Journal of chromatography, 1984, Jun-08, Volume: 308

    Topics: Benzothiazoles; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Erythrocytes; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Methylation; Pyrogallol; Spectrometry, Fluorescence; Thiazoles

1984
The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism.
    Journal of general microbiology, 1981, Volume: 126, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Microbial; Escherichia coli; Methylation; Pentoses; Peptide Elongation Factors; Ribosomes; Streptomyces; Thiazoles; Thiostrepton

1981
[Transmethylating activity of arginine thiazolidinecarboxylate (ATCA) in acute CCL4 poisoning and diet-induced steatosis in the rat].
    Il Farmaco; edizione pratica, 1980, Volume: 35, Issue:6

    Topics: Animals; Arginine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diet; Fatty Liver; Male; Methylation; Rats; Thiazoles; Thiazolidines

1980
Inhibition of sterol 4-demethylation in Candida albicans by 6-amino-2-n-pentylthiobenzothiazole, a novel mechanism of action for an antifungal agent.
    Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:7

    Topics: Antifungal Agents; Candida albicans; Ergosterol; Methylation; Saccharomyces cerevisiae; Thiazoles

1995
Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Animals; Ascaridoidea; Cattle; Magnetic Resonance Spectroscopy; Methylation; Mitochondria; NADH Dehydrogenase; Structure-Activity Relationship; Thiazoles

1995
Novel antibiotics, amythiamicins. II. Structure elucidation of amythiamicin D.
    The Journal of antibiotics, 1994, Volume: 47, Issue:10

    Topics: Acetylation; Anti-Bacterial Agents; Chemical Phenomena; Chemistry, Physical; Hydrochloric Acid; Hydrolysis; Macrocyclic Compounds; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment; Thiazoles

1994
Does histamine stimulate cyclic AMP formation in the avian pineal gland via a novel (non-H1, non-H2, non-H3) histamine receptor subtype.
    Neurochemistry international, 1995, Volume: 27, Issue:6

    Topics: Animals; Benzothiazoles; Chickens; Cyclic AMP; Ducks; Histamine; Histamine Agonists; Histamine H2 Antagonists; Ion Channels; Male; Methylation; Phenoxypropanolamines; Pineal Gland; Piperidines; Receptors, Histamine; Stimulation, Chemical; Thiazoles

1995
Identification of the metabolites of a new oxazolidinone MAO-A inhibitor in rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:10

    Topics: Animals; Benzothiazoles; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Methylation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Thiazoles

1997
Solution-phase synthesis of a hindered N-methylated tetrapeptide using Bts-protected amino acid chlorides: efficient coupling and methylation steps allow purification by extraction.
    The Journal of organic chemistry, 2000, Apr-21, Volume: 65, Issue:8

    Topics: Acylation; Amino Acids; Benzothiazoles; Chlorides; Cyclosporine; Methylation; Oligopeptides; Sulfones; Thiazoles

2000
Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation.
    The Journal of biological chemistry, 2000, Aug-18, Volume: 275, Issue:33

    Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Cell Death; Coloring Agents; Congo Red; Dose-Response Relationship, Drug; Fluorescent Dyes; Methylation; Microscopy, Electron; PC12 Cells; Peptide Biosynthesis; Peptide Fragments; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Rats; Spectrophotometry; Tetrazolium Salts; Thiazoles

2000
A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma.
    Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:10

    Topics: 3T3 Cells; Adipocytes; Animals; Cell Differentiation; CREB-Binding Protein; Drug Synergism; Ligands; Methylation; Mice; Nicotinic Acids; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Oleanolic Acid; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Repressor Proteins; Retinoid X Receptors; Rosiglitazone; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcriptional Activation

2000
Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues.
    Biochemistry, 2001, Jul-27, Volume: 40, Issue:28

    Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Benzothiazoles; Chymotrypsin; Drug Resistance; Humans; Methylation; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Thiazoles; Ultracentrifugation

2001
Troglitazone downregulates delta-6 desaturase gene expression in human skeletal muscle cell cultures.
    Diabetes, 2002, Volume: 51, Issue:4

    Topics: Adult; Cells, Cultured; Cholesterol Esters; Chromans; Dose-Response Relationship, Drug; Fatty Acid Desaturases; Female; Gene Amplification; Gene Expression Regulation, Enzymologic; Humans; Hypoglycemic Agents; Kinetics; Linoleoyl-CoA Desaturase; Male; Methylation; Muscle, Skeletal; Receptors, Cytoplasmic and Nuclear; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone

2002
Changes in GE2270 antibiotic production in Planobispora rosea through modulation of methylation metabolism.
    Microbiology (Reading, England), 2003, Volume: 149, Issue:Pt 6

    Topics: Actinomycetales; Adenosine; Anti-Bacterial Agents; Culture Media; Drug Interactions; Fermentation; Methionine; Methylation; Molecular Structure; Peptides; Peptides, Cyclic; Thiazoles; Vitamin B 12

2003
NMR investigation of the alkaline-like conformational transition of horse heart cytochrome c in the presence of exogenous thiazole.
    Biophysical chemistry, 2003, Jun-01, Volume: 104, Issue:2

    Topics: Alkalies; Animals; Cytochromes c; Heart; Heme; Horses; Hydrogen-Ion Concentration; Isomerism; Ligands; Magnetic Resonance Spectroscopy; Methylation; Molecular Structure; Protein Conformation; Protons; Thiazoles; Titrimetry

2003
Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
    Chemistry & biology, 2003, Volume: 10, Issue:8

    Topics: Anti-Bacterial Agents; Bacteriocins; Base Sequence; Binding Sites; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Thiazoles; Thiostrepton

2003
Synthesis of some functionalized arylaminomethyl-1 ,2,4-triazoles, 1,3,4-oxa- and thiadiazoles.
    Die Pharmazie, 2003, Volume: 58, Issue:11

    Topics: Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Enzyme-Linked Immunosorbent Assay; Hepatitis B virus; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methylation; Oxazoles; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Triazoles

2003
Discovery of potent and selective beta-homophenylalanine based dipeptidyl peptidase IV inhibitors.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Aminobutyrates; Animals; Biological Availability; Dipeptidyl Peptidase 4; Half-Life; Methylation; Protease Inhibitors; Rats; Structure-Activity Relationship; Thiazoles

2004
Occurrence of benzothiazoles in municipal wastewater and their fate in biological treatment.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Benzothiazoles; Bioreactors; Cities; Mass Spectrometry; Membranes, Artificial; Methylation; Sewage; Thiazoles; Time Factors; Waste Disposal, Fluid; Water Purification

2004
5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Annexin A5; Apoptosis; Azacitidine; Benzothiazoles; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA, Complementary; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; G2 Phase; GADD45 Proteins; Humans; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Methylation; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Toluene; Tumor Suppressor Protein p53

2005
Formation of Langmuir layers and surface modification using new upper-rim fully tethered bipyridinyl or bithiazolyl cyclodextrins and their fluorescent metal complexes.
    Langmuir : the ACS journal of surfaces and colloids, 2004, Jun-22, Volume: 20, Issue:13

    Topics: Cyclodextrins; Fluorescence; Isomerism; Ligands; Metals; Methylation; Microscopy; Molecular Structure; Optical Devices; Pyridines; Thiazoles

2004
Samarium Barbier reactions of alpha-iodomethyloxazoles and thiazoles with aliphatic aldehydes.
    Organic letters, 2005, Sep-15, Volume: 7, Issue:19

    Topics: Aldehydes; Heterocyclic Compounds, 4 or More Rings; Iodine; Methylation; Molecular Structure; Oxazoles; Samarium; Thiazoles

2005
Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues.
    Bioorganic & medicinal chemistry, 2005, Dec-15, Volume: 13, Issue:24

    Topics: Aminobutyrates; Animals; Carboxylic Acids; Cells, Cultured; Cross-Linking Reagents; Dipeptides; Growth Hormone; Male; Methylation; Molecular Structure; Phenanthrenes; Pituitary Gland; Rats; Rats, Sprague-Dawley; Serine; Structure-Activity Relationship; Thiazoles

2005
Identification of an amyloidogenic region on keratoepithelin via synthetic peptides.
    FEBS letters, 2007, Jan-23, Volume: 581, Issue:2

    Topics: Amino Acid Sequence; Amyloid; Benzothiazoles; Circular Dichroism; Congo Red; Extracellular Matrix Proteins; Fluorescence; Humans; Methylation; Molecular Sequence Data; Mutation; Peptides; Protein Structure, Secondary; Thiazoles; Transforming Growth Factor beta

2007
Cytotoxicity of different types of methylated beta-cyclodextrins and ionic derivatives.
    Die Pharmazie, 2007, Volume: 62, Issue:7

    Topics: Antineoplastic Agents; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; HeLa Cells; Humans; Indicators and Reagents; Methylation; Tetrazolium Salts; Thiazoles

2007
Influence of the metabolic profile on the in vivo antioxidant activity of quercetin under a low dosage oral regimen in rats.
    British journal of pharmacology, 2008, Volume: 153, Issue:8

    Topics: Animals; Antioxidants; Benzothiazoles; Chromatography, High Pressure Liquid; Glucuronides; Male; Methylation; Quercetin; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Sulfates; Sulfonic Acids; Thiazoles

2008
Methylated N-(4-N,N-dimethylaminobenzyl) chitosan, a novel chitosan derivative, enhances paracellular permeability across intestinal epithelial cells (Caco-2).
    AAPS PharmSciTech, 2008, Volume: 9, Issue:4

    Topics: Caco-2 Cells; Chitosan; Dextrans; Fluorescein-5-isothiocyanate; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Magnetic Resonance Spectroscopy; Methylation; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Tight Junctions

2008
Crystal structure of the nosiheptide-resistance methyltransferase of Streptomyces actuosus.
    Biochemistry, 2010, Aug-03, Volume: 49, Issue:30

    Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Drug Resistance, Bacterial; Methylation; Methyltransferases; Protein Multimerization; RNA; Streptomyces; Substrate Specificity; Thiazoles

2010
Arabidopsis histone methyltransferase SET DOMAIN GROUP8 mediates induction of the jasmonate/ethylene pathway genes in plant defense response to necrotrophic fungi.
    Plant physiology, 2010, Volume: 154, Issue:3

    Topics: Alternaria; Arabidopsis; Arabidopsis Proteins; Botrytis; Cyclopentanes; Ethylenes; Gene Expression Regulation, Plant; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Indoles; Methylation; Oxylipins; Plant Diseases; Plant Growth Regulators; Plant Immunity; Promoter Regions, Genetic; RNA, Plant; Thiazoles

2010
The cysteine reaction with diacetyl under wine-like conditions: proposed mechanisms for mixed origins of 2-methylthiazole, 2-methyl-3-thiazoline, 2-methylthiazolidine, and 2,4,5-trimethyloxazole.
    Journal of food science, 2011, Volume: 76, Issue:6

    Topics: Acetaldehyde; Cysteine; Databases, Factual; Diacetyl; Gas Chromatography-Mass Spectrometry; Hexanones; Methylation; Models, Chemical; Oxazoles; Thiazoles; Volatile Organic Compounds; Wine

2011
Fully automated and reproducible radiosynthesis of high specific activity [¹¹C]raclopride and [¹¹C]Pittsburgh compound-B using the combination of two commercial synthesizers.
    Nuclear medicine communications, 2011, Volume: 32, Issue:11

    Topics: Aniline Compounds; Carbon Radioisotopes; Hydrocarbons, Iodinated; Isotope Labeling; Mesylates; Methylation; Raclopride; Radiochemistry; Radiopharmaceuticals; Reproducibility of Results; Thiazoles

2011
Binding of the three-repeat domain of tau to phospholipid membranes induces an aggregated-like state of the protein.
    Biochimica et biophysica acta, 2012, Volume: 1818, Issue:9

    Topics: Alzheimer Disease; Amino Acid Sequence; Benzothiazoles; Biophysics; Circular Dichroism; Humans; Lipid Bilayers; Lipids; Liposomes; Lysine; Magnetic Resonance Spectroscopy; Methylation; Molecular Sequence Data; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity; tau Proteins; Thiazoles; Unilamellar Liposomes

2012
Reduction and methylation of ziprasidone by glutathione, aldehyde oxidase, and thiol S-methyltransferase in humans: an in vitro study.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:11

    Topics: Aldehyde Oxidase; Antipsychotic Agents; Cytosol; Glutathione; Humans; Liver; Methylation; Methyltransferases; Microsomes, Liver; Oxidation-Reduction; Piperazines; Thiazoles

2012
Structure and radical scavenging activity relationships of pyrolytic lignins.
    Journal of agricultural and food chemistry, 2012, Dec-26, Volume: 60, Issue:51

    Topics: Acetylation; Antioxidants; Benzothiazoles; Biphenyl Compounds; Free Radical Scavengers; Hot Temperature; Lignans; Magnetic Resonance Spectroscopy; Methylation; Picrates; Structure-Activity Relationship; Sulfonic Acids; Thiazoles

2012
Homocysteine-induced hypermethylation of DDAH2 promoter contributes to apoptosis of endothelial cells.
    Die Pharmazie, 2013, Volume: 68, Issue:4

    Topics: Amidohydrolases; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Survival; Coloring Agents; Endothelial Cells; Homocysteine; Methylation; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Repressor Proteins; Tetrazolium Salts; Thiazoles

2013
ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1.
    The Journal of biological chemistry, 2014, Oct-10, Volume: 289, Issue:41

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Jumonji Domain-Containing Histone Demethylases; Luciferases; Mammary Glands, Human; Methylation; Models, Molecular; Molecular Sequence Data; Neuregulin-1; Protein Binding; Protein-Tyrosine Kinases; Pyrimidines; Receptor, ErbB-2; Signal Transduction; Tamoxifen; Thiazoles; Transcription, Genetic

2014
Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides.
    Angewandte Chemie (International ed. in English), 2015, Feb-16, Volume: 54, Issue:8

    Topics: Acyl Carrier Protein; Epothilones; Mass Spectrometry; Methylation; Phenols; Polyketide Synthases; Polyketides; Thiazoles

2015
Regioselective oxidative trifluoromethylation of imidazoheterocycles via C(sp2)-H bond functionalization.
    The Journal of organic chemistry, 2015, Feb-06, Volume: 80, Issue:3

    Topics: Catalysis; Hydrogen Bonding; Imidazoles; Methylation; Molecular Structure; Oxidation-Reduction; Pyridines; Stereoisomerism; Thiazoles

2015
3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin analogues with antiproliferative activity.
    Marine drugs, 2015, Apr-03, Volume: 13, Issue:4

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Design; G2 Phase; Halogenation; Humans; Imidazoles; Indoles; Membrane Potential, Mitochondrial; Methylation; Mitochondria; Molecular Structure; Neoplasms; Pyridines; Pyrroles; Resting Phase, Cell Cycle; Thiazoles

2015
Substrate recognition and modification by the nosiheptide resistance methyltransferase.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Anti-Bacterial Agents; Binding Sites; Drug Resistance, Bacterial; Enzyme Activation; Methylation; Methyltransferases; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Multimerization; RNA; Substrate Specificity; Thiazoles

2015
Going Out on a Limb: Delineating The Effects of β-Branching, N-Methylation, and Side Chain Size on the Passive Permeability, Solubility, and Flexibility of Sanguinamide A Analogues.
    Journal of medicinal chemistry, 2015, Sep-24, Volume: 58, Issue:18

    Topics: Caco-2 Cells; Humans; Membranes, Artificial; Methylation; Molecular Dynamics Simulation; Peptides, Cyclic; Permeability; Solubility; Structure-Activity Relationship; Thiazoles; Water

2015
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Halogenation; Histone Deacetylase Inhibitors; Humans; Ketones; Methylation; Neoplasms; Structure-Activity Relationship; Thiazoles; Zinc

2016
Quantification of vosaroxin and its metabolites N-desmethylvosaroxin and O-desmethylvosaroxin in human plasma and urine using high-performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Aug-01, Volume: 1027

    Topics: Antineoplastic Agents; Body Fluids; Chemical Precipitation; Chromatography, High Pressure Liquid; Humans; Limit of Detection; Methylation; Naphthyridines; Reproducibility of Results; Tandem Mass Spectrometry; Thiazoles

2016
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
    Neuropharmacology, 2017, Volume: 113, Issue:Pt A

    Topics: Animals; Astrocytes; Cell Survival; Cells, Cultured; Corticosterone; CpG Islands; Endoplasmic Reticulum Stress; Methylation; MicroRNAs; PPAR delta; PPAR-beta; Rats; Rats, Sprague-Dawley; Thiazoles

2017
The Catalytic Mechanism of the Class C Radical S-Adenosylmethionine Methyltransferase NosN.
    Angewandte Chemie (International ed. in English), 2017, 03-27, Volume: 56, Issue:14

    Topics: Anti-Bacterial Agents; Catalysis; Free Radicals; Methylation; Methyltransferases; Molecular Structure; S-Adenosylmethionine; Thiazoles

2017
The requirement of Mettl3-promoted
    Open biology, 2017, Volume: 7, Issue:9

    Topics: 5' Untranslated Regions; Adenosine; Animals; Cell Differentiation; Cell Line; Cell Proliferation; ELAV-Like Protein 1; G2 Phase; Gene Expression Regulation; Methylation; Methyltransferases; Mice; Muscle Development; Muscle, Skeletal; Myoblasts; MyoD Protein; Quinolines; RNA, Small Interfering; S Phase; Signal Transduction; Thiazoles; Thymidine

2017
NosN, a Radical S-Adenosylmethionine Methylase, Catalyzes Both C1 Transfer and Formation of the Ester Linkage of the Side-Ring System during the Biosynthesis of Nosiheptide.
    Journal of the American Chemical Society, 2017, 12-06, Volume: 139, Issue:48

    Topics: Methylation; Methyltransferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thiazoles

2017
Homochiral versus Heterochiral Trifluoromethylated Pseudoproline Containing Dipeptides: A Powerful Tool to Switch the Prolyl-Amide Bond Conformation.
    The Journal of organic chemistry, 2017, 12-15, Volume: 82, Issue:24

    Topics: Amides; Dipeptides; Fluorine; Methylation; Molecular Structure; Proline; Stereoisomerism; Thiazoles

2017
Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase.
    Journal of the American Chemical Society, 2017, 12-27, Volume: 139, Issue:51

    Topics: Anti-Bacterial Agents; Deoxyadenosines; Hydrogen; Methylation; Methyltransferases; Peptides, Cyclic; Protons; S-Adenosylhomocysteine; S-Adenosylmethionine; Solvents; Thiazoles

2017
Enhancing the Cancer Cell Growth Inhibitory Effects of Table Grape Anthocyanins.
    Journal of food science, 2018, Volume: 83, Issue:9

    Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Caco-2 Cells; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Female; Fruit; Glucosides; HT29 Cells; Humans; Methylation; Nitriles; Oxidative Stress; Phytotherapy; Plant Extracts; Tetrazolium Salts; Thiazoles; Vitis

2018
Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide.
    Methods in enzymology, 2018, Volume: 606

    Topics: Bacterial Proteins; Biosynthetic Pathways; Enzyme Assays; Methylation; Methyltransferases; Peptides; Recombinant Proteins; S-Adenosylmethionine; Streptomyces; Thiazoles

2018
Stuffed Methyltransferase Catalyzes the Penultimate Step of Pyochelin Biosynthesis.
    Biochemistry, 2019, 02-12, Volume: 58, Issue:6

    Topics: Bacterial Proteins; Catalysis; Catechol O-Methyltransferase; Escherichia coli; Kinetics; Methanocaldococcus; Methionine Adenosyltransferase; Methylation; Methyltransferases; Peptide Synthases; Phenols; Protein Domains; Pseudomonas aeruginosa; S-Adenosylmethionine; Thiazoles

2019
CF
    Chemical communications (Cambridge, England), 2019, Oct-25, Volume: 55, Issue:83

    Topics: Hydrogen Bonding; Methylation; Molecular Conformation; Peptides; Proline; Stereoisomerism; Thiazoles; Toluene

2019
Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry.
    SLAS discovery : advancing life sciences R & D, 2021, Volume: 26, Issue:6

    Topics: Antiparasitic Agents; Antiviral Agents; Cloning, Molecular; COVID-19; Drug Repositioning; Enzyme Assays; Enzyme Inhibitors; Escherichia coli; Exoribonucleases; Gene Expression; Genetic Vectors; High-Throughput Screening Assays; Humans; Kinetics; Mass Spectrometry; Methylation; Nitro Compounds; Prescription Drugs; Recombinant Fusion Proteins; RNA Caps; RNA, Viral; SARS-CoV-2; Small Molecule Libraries; Thiazoles; Viral Nonstructural Proteins; Virus Replication

2021