Page last updated: 2024-08-21

thiazoles and imidazole

thiazoles has been researched along with imidazole in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (10.34)	18.7374
1990's	1 (3.45)	18.2507
2000's	7 (24.14)	29.6817
2010's	15 (51.72)	24.3611
2020's	3 (10.34)	2.80

Authors

Authors	Studies
Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T	1
Fotsch, C; St Jean, DJ	1
Carbone, D; Cascioferro, S; Cirrincione, G; Diana, P; Giovannetti, E; Parrino, B; Schillaci, D	1
Golovinsky, EV; Jung, G; Stankova, IG; Videnov, GI	1
Johar, M; Lown, JW; Reddy, BS; Singhal, N; Sondhi, SM	1
BOREL, LJ; DUREL, P; ROIRON, V; SIBOULET, A	1
YURA, Y	1
Bu, XR; De Boni, L; Feng, K; Hsu, FL; Meador, M; Mendonca, CR; Misoguti, L	1
Li, DF; Li, HD; Xian, YF; Yu, BH	1
Baron, O; Ila, H; Knochel, P; Wagner, AJ	1
Böhlmann, W; Findeisen, M; Gelbrich, T; Hofmann, HJ; Schulze, B; Wolf, J	1
Boduszek, B; Kudelski, A; Olszewski, TK; Podstawka, E	1
Dorgan, KM; Mosley, SL; Sadler, JM; Seley-Radtke, KL; Zhou, ZS	1
Frimurer, TM; Grimstrup, M; Högberg, T; Mathiesen, JM; Nielsen, PA; Receveur, JM; Rist, Ø	1
Hong, Y; Rugang, Z; Xiaohe, Z; Xiuqing, S; Yu, Q	1
Barrish, JC; Burke, JR; Chen, L; Dodd, JH; Dyckman, AJ; Gill, P; Gillooly, KM; Guo, J; Kempson, J; Langevine, CM; Li, T; McIntyre, KW; McKinnon, M; Nirschl, DS; Pattoli, MA; Pitts, WJ; Quesnelle, C; Spergel, SH; Watterson, SH	1
Comba, P; Dovalil, N; Hanson, GR; Linti, G	1
Bernini, SK; Bolchi, C; Chiodini, G; Corsini, A; Ferri, N; Fumagalli, L; Pallavicini, M; Straniero, V; Valoti, E	1
Böhler, P; Hamacher, A; Kassack, MU; Kunz, PC; Ott, I; Rubbiani, R; Spingler, B; Watjen, W; Wetzel, C	1
Alsop, L; Bright, H; Dayal, S; Galan, S; Gardner, I; Middleton, DS; Murray, EJ; Parkinson, T; Platts, M; Pryde, DC; Stupple, P; Tran, TD; Watson, L; Webster, R	1
Bajpai, M; Banerjee, A; Gharat, LA; Gudi, GS; Gullapalli, S; Jadhav, S; Kadam, PA; Khairatkar-Joshi, N; Kumar, H; Merugu, RR; More, SV; Narayana, L; Pisal, DV; Raje, FA; Sangana, RR; Voleti, SR	1
Comba, P; Gahan, LR; Hanson, GR; Maeder, M; Westphal, M	1
Bharatam, PV; Bhatia, S	1
Balakrishna, M; Faazil, S; Kamal, A; Nayak, VL; Nimbarte, VD; Shaik, TB	1
Alapati, A; Bergmeier, SC; Burdick, MM; Carlson, GE; Deosarkar, SP; Goetz, DJ; Lanier, OL; McCall, KD; Qi, C; Schwartz, FL	1
Gong, H; Huang, K; Huang, L; Liu, J; Petersen, RB; Sun, Y; Yang, X; Zhang, X; Zheng, L	1
Aprile, S; Fallarini, S; Massarotti, A; Pirali, T; Serafini, M; Torre, E	1
Gonçalves, TP; Huang, KW; Jiang, Z; Li, Y; Qiao, B; Wang, G; Yin, Y; Zhan, Q; Zhao, X	1
Abdel-Maksoud, MS; Alach, NN; Anbar, HS; El-Gamal, MI; El-Gamal, R; Oh, CH; Sbenati, RM; Shehata, MK; Tarazi, H; Zaraei, SO	1

Reviews

3 review(s) available for thiazoles and imidazole

Article	Year
Mitigating heterocycle metabolism in drug discovery. Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13 Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats	2012
Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance. Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15 Topics: Animals; Anti-Bacterial Agents; Benzene; Biofilms; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Thiazolidines	2020
Heterocyclic compounds as inflammation inhibitors. Current medicinal chemistry, 2002, Volume: 9, Issue:10 Topics: Acridines; Alkanes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Carboxylic Acids; Gastrointestinal Diseases; Heterocyclic Compounds; Humans; Imidazoles; Pyrimidines; Thiazoles; Thiourea	2002

Other Studies

26 other study(ies) available for thiazoles and imidazole

Article	Year
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives. Journal of medicinal chemistry, 1981, Volume: 24, Issue:10 Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase	1981
Synthesis of thiazole, imidazole and oxazole containing amino acids for peptide backbone modification. Journal of peptide science : an official publication of the European Peptide Society, 1999, Volume: 5, Issue:9 Topics: Amino Acids; Anti-Bacterial Agents; Bacteriocins; Imidazoles; Molecular Mimicry; Oxazoles; Peptides; Thiazoles	1999
Systemic treatment of human trichomoniasis with a derivative of nitro-imidazole, 8823 RP. The British journal of venereal diseases, 1960, Volume: 36 Topics: Female; Humans; Imidazoles; Thiazoles; Trichomonas Infections; Vaginitis	1960
Studies on acetylenic compounds. XXII. Ring closure. (4). New synthesis of thiazoles and imidazole. Chemical & pharmaceutical bulletin, 1962, Volume: 10 Topics: Acetylene; Alkynes; Imidazoles; Thiazoles	1962
Y-shaped two-photon absorbing molecules with an imidazole-thiazole core. Chemical communications (Cambridge, England), 2004, May-21, Issue:10 Topics: Absorptiometry, Photon; Imidazoles; Thiazoles	2004
[Synthesis of byrazoline fluorescent compounds and studies by infrared spectroscopy]. Guang pu xue yu guang pu fen xi = Guang pu, 2005, Volume: 25, Issue:3 Topics: Azoles; Fluorescence; Fluorescent Dyes; Imidazoles; Molecular Structure; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Thiazoles	2005
Functionalized magnesium organometallics as versatile intermediates for the synthesis of polyfunctional heterocycles. Chemical communications (Cambridge, England), 2006, Feb-14, Issue:6 Topics: Antipyrine; Combinatorial Chemistry Techniques; Esters; Furans; Heterocyclic Compounds; Imidazoles; Imines; Iodides; Magnesium; Models, Chemical; Nitriles; Organometallic Compounds; Pyridines; Pyrroles; Quinolines; Thiazoles; Thiophenes; Uracil	2006
Synthesis of stable isothiazole carbenes. Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:17 Topics: Crystallography, X-Ray; Dimerization; Hydrocarbons; Imidazoles; Methane; Models, Molecular; Molecular Structure; Protons; Thermodynamics; Thiazoles	2007
Surface-enhanced Raman scattering studies on the interaction of phosphonate derivatives of imidazole, thiazole, and pyridine with a silver electrode in aqueous solution. The journal of physical chemistry. B, 2009, Jul-23, Volume: 113, Issue:29 Topics: Electrochemistry; Electrodes; Imidazoles; Molecular Structure; Organophosphonates; Pyridines; Silver; Solutions; Spectrum Analysis, Raman; Surface Properties; Thiazoles; Water	2009
Synthetic strategies toward carbocyclic purine-pyrimidine hybrid nucleosides. Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15 Topics: Adenosylhomocysteinase; Enzyme Inhibitors; Imidazoles; Molecular Structure; Purine Nucleosides; Pyrimidine Nucleosides; Thiazoles; Uracil	2009
Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists. Bioorganic & medicinal chemistry letters, 2010, Mar-01, Volume: 20, Issue:5 Topics: Animals; Benzhydryl Compounds; Binding Sites; Cell Line; Computer Simulation; Humans; Hydrogen Bonding; Imidazoles; Mice; Models, Molecular; Nitrogen; Pyrimidines; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship; Thiazoles	2010
Synthesis, biological evaluation and molecular modeling studies of N-aryl-2-arylthioacetamides as non-nucleoside HIV-1 reverse transcriptase inhibitors. Chemical biology & drug design, 2010, Volume: 76, Issue:4 Topics: Binding Sites; Cell Line; Computer Simulation; HIV Reverse Transcriptase; HIV-1; Humans; Imidazoles; Models, Molecular; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Thiazoles; Thioacetamide; Triazoles	2010
Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis. Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1 Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; I-kappa B Kinase; Imidazoles; Mice; Mice, Inbred BALB C; Protein Kinase Inhibitors; Pyridines; Rats; Structure-Activity Relationship; Thiazoles	2011
Synthesis and Cu(II) coordination chemistry of a patellamide derivative: consequences of the change from the natural thiazole/oxazoline to the artificial imidazole heterocycles. Inorganic chemistry, 2011, Jun-06, Volume: 50, Issue:11 Topics: Amides; Copper; Crystallography, X-Ray; Heterocyclic Compounds; Imidazoles; Models, Molecular; Molecular Conformation; Organometallic Compounds; Oxazoles; Peptides, Cyclic; Quantum Theory; Stereoisomerism; Thiazoles	2011
Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase. Bioorganic & medicinal chemistry letters, 2011, Sep-15, Volume: 21, Issue:18 Topics: Animals; Aorta; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Farnesyltranstransferase; Imidazoles; Molecular Structure; Myocytes, Smooth Muscle; Peptidomimetics; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles	2011
Gold(I) complexes of water-soluble diphos-type ligands: synthesis, anticancer activity, apoptosis and thioredoxin reductase inhibition. Dalton transactions (Cambridge, England : 2003), 2011, Sep-28, Volume: 40, Issue:36 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Humans; Imidazoles; Models, Molecular; Organogold Compounds; Rats; Thiazoles; Thioredoxin-Disulfide Reductase	2011
Non-benzimidazole containing inhibitors of respiratory syncytial virus. Bioorganic & medicinal chemistry letters, 2013, Feb-01, Volume: 23, Issue:3 Topics: Animals; Antiviral Agents; Benzimidazoles; Imidazoles; Inhibitory Concentration 50; Rats; Respiratory Syncytial Viruses; Structure-Activity Relationship; Thiazoles	2013
Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors. Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24 Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Evaluation, Preclinical; Enzyme Activation; Female; Half-Life; Imidazoles; Molecular Docking Simulation; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles	2013
Carbonic anhydrase activity of dinuclear Cu(II) complexes with patellamide model ligands. Dalton transactions (Cambridge, England : 2003), 2014, Feb-28, Volume: 43, Issue:8 Topics: Carbonic Anhydrases; Catalysis; Coordination Complexes; Copper; Imidazoles; Kinetics; Ligands; Models, Molecular; Peptides, Cyclic; Stereoisomerism; Thiazoles	2014
Possibility of the existence of donor-acceptor interactions in bis(azole)amines: an electronic structure analysis. The Journal of organic chemistry, 2014, Jun-06, Volume: 79, Issue:11 Topics: Amines; Azoles; Computer Simulation; Electrons; Imidazoles; Ligands; Models, Molecular; Molecular Structure; Nitrogen; Thiazoles	2014
Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents. ChemMedChem, 2014, Volume: 9, Issue:12 Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chalcone; DNA Fragmentation; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; HeLa Cells; HT29 Cells; Humans; Imidazoles; Immunohistochemistry; M Phase Cell Cycle Checkpoints; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Thiazoles; Tubulin; Tubulin Modulators	2014
Simple modifications to methimazole that enhance its inhibitory effect on tumor necrosis factor-α-induced vascular cell adhesion molecule-1 expression by human endothelial cells. European journal of pharmacology, 2015, Mar-15, Volume: 751 Topics: Biomechanical Phenomena; Cell Adhesion; Cell Line; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Methimazole; Monocytes; RNA, Messenger; Structure-Activity Relationship; Thiazoles; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2015
How the imidazole ring modulates amyloid formation of islet amyloid polypeptide: A chemical modification study. Biochimica et biophysica acta, 2016, Volume: 1860, Issue:4 Topics: Benzothiazoles; Diethyl Pyrocarbonate; Humans; Imidazoles; Islet Amyloid Polypeptide; Molecular Dynamics Simulation; Multiprotein Complexes; Protein Structure, Secondary; Thiazoles	2016
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors. Molecules (Basel, Switzerland), 2019, May-15, Volume: 24, Issue:10 Topics: Binding Sites; Catalytic Domain; Click Chemistry; Enzyme Inhibitors; Humans; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Thiazoles	2019
All-Carbon Quaternary Stereocenters α to Azaarenes via Radical-Based Asymmetric Olefin Difunctionalization. Journal of the American Chemical Society, 2020, 11-18, Volume: 142, Issue:46 Topics: Alkenes; Aza Compounds; Benzimidazoles; Carbon; Catalysis; Cyclization; Cyclopentanes; Diphosphonates; Free Radicals; Imidazoles; Models, Molecular; Oxidation-Reduction; Photochemical Processes; Quinolines; Stereoisomerism; Thiazoles	2020
Discovery of first-in-class imidazothiazole-based potent and selective ErbB4 (HER4) kinase inhibitors. European journal of medicinal chemistry, 2021, Nov-15, Volume: 224 Topics: Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Imidazoles; Molecular Docking Simulation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Receptor, ErbB-4; Structure-Activity Relationship; Thiazoles	2021