Page last updated: 2024-08-21

thiazoles and hypoxanthine

thiazoles has been researched along with hypoxanthine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Higashino, K; Hiroishi, K; Moriwaki, Y; Nasako, Y; Takahashi, S; Yamakita, J; Yamamoto, T1
Fujimura, Y; Hada, T; Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsui, T; Tsutsumi, Z; Yamamoto, T1
Grabowski, BA; Joseph-Ridge, N; Khosravan, R; Vernillet, L; Wu, JT1
Joseph-Ridge, N; Khosravan, R; Kukulka, MJ; Vernillet, L; Wu, JT1
Alegría, AE; Colón, IG; Cordero, M; Cox, O; González, FA; Kumar, A; Velez, C; Zayas, B1
Iwasaki, H; Kishi, S; Matsuda, Y; Nakamura, T; Ookura, M; Tai, K; Takai, M; Ueda, T; Yamauchi, T; Yoshida, A1

Trials

2 trial(s) available for thiazoles and hypoxanthine

ArticleYear
Pharmacokinetics, pharmacodynamics and safety of febuxostat, a non-purine selective inhibitor of xanthine oxidase, in a dose escalation study in healthy subjects.
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Dose-Response Relationship, Drug; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Models, Biological; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase

2006
The effect of age and gender on pharmacokinetics, pharmacodynamics, and safety of febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Biotransformation; Enzyme Inhibitors; Febuxostat; Female; Gout Suppressants; Humans; Hypoxanthine; Male; Protein Binding; Sex Factors; Thiazoles; Uric Acid; Xanthine; Xanthine Oxidase; Young Adult

2008

Other Studies

4 other study(ies) available for thiazoles and hypoxanthine

ArticleYear
Determination of plasma purine nucleoside phosphorylase activity by high-performance liquid chromatography.
    Analytical biochemistry, 1995, May-01, Volume: 227, Issue:1

    Topics: Adult; Aged; Asthma; Calibration; Chromatography, High Pressure Liquid; Febuxostat; Female; Gout; Gout Suppressants; Humans; Hypoxanthine; Hypoxanthines; Inosine; Male; Middle Aged; Purine-Nucleoside Phosphorylase; Thiazoles; Uric Acid; Xanthine Oxidase

1995
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
    Pharmacology, 2000, Volume: 60, Issue:1

    Topics: Allopurinol; Biological Transport; Carrier Proteins; Drug Interactions; Enzyme Inhibitors; Febuxostat; Humans; Hypoxanthine; Inosine; Lung Neoplasms; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Pentosyltransferases; Purines; Pyrimidine Phosphorylases; Thiazoles; Tumor Cells, Cultured; Uracil; Uridine; Xanthine; Xanthine Oxidase

2000
Role of the nitro functionality in the DNA binding of 3-nitro-10-methylbenzothiazolo[3,2-a]quinolinium chloride.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Animals; Binding Sites; Cattle; Cell Survival; Chromatography, Liquid; DNA; DNA Adducts; Drug Screening Assays, Antitumor; Humans; Hypoxanthine; Molecular Structure; Oxidation-Reduction; Quinolinium Compounds; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured; Uric Acid; Xanthine Oxidase

2008
Febuxostat for management of tumor lysis syndrome including its effects on levels of purine metabolites in patients with hematological malignancies - a single institution's, pharmacokinetic and pilot prospective study.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Aged; Allopurinol; Antineoplastic Agents; Creatinine; Enzyme Inhibitors; Febuxostat; Female; Glomerular Filtration Rate; Hematologic Neoplasms; Humans; Hypoxanthine; Male; Middle Aged; Pilot Projects; Prospective Studies; Thiazoles; Tumor Lysis Syndrome; Uric Acid; Xanthine; Xanthine Oxidase

2014