thiazoles has been researched along with guanosine triphosphate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 8 (34.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anborgh, PH; Parmeggiani, A | 2 |
| Bai, R; Hamel, E; Pettit, GR | 1 |
| Chiang, CF; Hauser, G | 1 |
| Abel, K; Hilgenfeld, R; Jurnak, F; Yoder, MD | 1 |
| Giannakakou, P; Hamel, E; Kowalski, RJ | 1 |
| Eliot, AC; Kelleher, NL; Milne, JC; Walsh, CT | 1 |
| Hamel, E; Nicolaou, KC; Sackett, DL; Vourloumis, D | 1 |
| Endo, Y; Kanno, M; Tamura, M | 1 |
| Hilgenfeld, R; Jurnak, F; Kraal, B; Martien de Graaf, J; Mesters, JR; Mörhle, VG; Olsthoorn-Tieleman, LN; van Duyl, BY; Zuurmond, AM | 1 |
| Kasparian, J; Meurer-Grob, P; Wade, RH | 1 |
| Dagher, PC; Kelly, KJ; Plotkin, Z; Vulgamott, SL | 1 |
| Aboul-ela, F; Klinck, R; Lentzen, G; Matassova, N; Murchie, AI | 1 |
| Anborgh, PH; Okamura, S; Parmeggiani, A | 1 |
| Bezard, E; Guo, S; Zhao, B | 1 |
| Ahn, S; Dalton, JT; Li, CM; Lu, Y; Miller, DD; Narayanan, R | 1 |
| Foss, MH; Garstecki, P; Holyst, R; Hou, S; Kaminski, TS; Nieznanski, K; Shaw, JT; Sorto, NA; Tabaka, M; Thanbichler, M; Weibel, DB; Wieczorek, SA; Ziebacz, N | 1 |
| April, DG; Geiss, BJ; Hannah, AM; Keenan, SM; Saeedi, BJ; Stahla-Beek, HJ | 1 |
| Dasgupta, S; Ghosh, S; Pandey, NK | 1 |
| Grøftehauge, MK; Morth, JP; Nissen, P; Skrydstrup, T; Taaning, R; Therkelsen, MØ | 1 |
| Hassan, HE; Kong, L; Li, T; Liu, J; MacKerell, AD; Park, JS; Smith, WW; Thomas, JM; Voulalas, P; Xue, F; Yang, D; Zhong, S | 1 |
| Andreu, JM; Chacón, P; López-Blanco, JR; Ramírez-Aportela, E | 1 |
| Brown, NE; Goldberg, JB; Prezioso, SM | 1 |
1 review(s) available for thiazoles and guanosine triphosphate
| Article | Year |
|---|---|
Elfamycins: inhibitors of elongation factor-Tu.
Topics: Actinomycetales; Actinomycetales Infections; Aminoglycosides; Anti-Bacterial Agents; Drug Design; Escherichia coli; Guanosine Triphosphate; Peptide Elongation Factor Tu; Peptides, Cyclic; Polyenes; Pyridones; Ribosomes; Thiazoles | 2017 |
22 other study(ies) available for thiazoles and guanosine triphosphate
| Article | Year |
|---|---|
New antibiotic that acts specifically on the GTP-bound form of elongation factor Tu.
Topics: Aminoglycosides; Anti-Bacterial Agents; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Molecular Structure; Peptide Chain Elongation, Translational; Peptide Elongation Factor Tu; Peptides; Peptides, Cyclic; Protein Binding; Ribosomes; Thiazoles | 1991 |
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
Topics: Amino Acid Sequence; Animals; Antibiotics, Antineoplastic; Aziridines; Cell Division; Cell Survival; Depsipeptides; Diamines; Drug Interactions; Guanosine Triphosphate; Mice; Mitotic Index; Molecular Sequence Data; Oligopeptides; Organophosphorus Compounds; Thiazoles; Tubulin; Tumor Cells, Cultured; Vinca Alkaloids; Vincristine | 1990 |
Effects of bradykinin, GTP gamma S, R59022 and N-ethylmaleimide on inositol phosphate production in NG108-15 cells.
Topics: Animals; Bradykinin; Cell Line; Drug Interactions; Ethylmaleimide; Glioma; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hybrid Cells; Inositol; Inositol Phosphates; Kinetics; Mice; Neuroblastoma; Platelet Activating Factor; Pyrimidinones; Rats; Thiazoles; Thionucleotides | 1989 |
Probing the reactivity of the GTP- and GDP-bound conformations of elongation factor Tu in complex with the antibiotic GE2270 A.
Topics: Anti-Bacterial Agents; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Mutation; Peptide Elongation Factor Tu; Peptides, Cyclic; Protein Conformation; Protein Denaturation; RNA, Transfer; Thiazoles | 1993 |
An alpha to beta conformational switch in EF-Tu.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Crystallography, X-Ray; Escherichia coli; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Peptide Elongation Factor Tu; Peptides, Cyclic; Protein Conformation; Species Specificity; Thiazoles | 1996 |
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).
Topics: Drug Resistance, Multiple; Epothilones; Epoxy Compounds; Guanosine Triphosphate; Humans; Kidney; Kinetics; Microtubule-Associated Proteins; Mitotic Index; Paclitaxel; Polymers; Thiazoles; Tubulin; Tumor Cells, Cultured | 1997 |
ATP/GTP hydrolysis is required for oxazole and thiazole biosynthesis in the peptide antibiotic microcin B17.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Bacteriocins; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Molecular Sequence Data; Multienzyme Complexes; Oxazoles; Peptides; Substrate Specificity; Thiazoles | 1998 |
The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.
Topics: Alkaloids; Animals; Antineoplastic Agents; Binding, Competitive; Cnidaria; Diterpenes; Docetaxel; Epothilones; Epoxy Compounds; Growth Inhibitors; Guanosine Triphosphate; Humans; Microtubule-Associated Proteins; Paclitaxel; Polymers; Protein Binding; Protein Processing, Post-Translational; Taxoids; Thiazoles; Tubulin; Tumor Cells, Cultured | 1999 |
Deactivation of neutrophil NADPH oxidase by actin-depolymerizing agents in a cell-free system.
Topics: Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell-Free System; Deoxyribonuclease I; Dose-Response Relationship, Drug; Edetic Acid; Enzyme Activation; Ethyldimethylaminopropyl Carbodiimide; Guanosine Triphosphate; Humans; Magnesium; NADPH Oxidases; Neutrophils; Oxygen; Sodium Dodecyl Sulfate; Subcellular Fractions; Thiazoles; Thiazolidines; Time Factors | 2000 |
GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes.
Topics: Actinomycetales; Adenine; Amino Acid Substitution; Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Microbial; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Mutation; Peptide Elongation Factor Tu; Peptides; Peptides, Cyclic; Poly U; Protein Binding; Protein Biosynthesis; Protein Conformation; RNA, Bacterial; RNA, Transfer, Amino Acyl; Thermodynamics; Thermus; Thiazoles | 2000 |
Microtubule structure at improved resolution.
Topics: Actin Cytoskeleton; Alkaloids; Amino Acid Sequence; Animals; Dimerization; Diterpenes; Docetaxel; Epothilones; Epoxy Compounds; Excipients; Guanosine Triphosphate; Microtubules; Molecular Sequence Data; Paclitaxel; Protein Conformation; Surface Properties; Swine; Taxoids; Thiazoles; Tubulin | 2001 |
P53 mediates the apoptotic response to GTP depletion after renal ischemia-reperfusion: protective role of a p53 inhibitor.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Guanosine; Guanosine Triphosphate; Kidney; Kidney Cortex; Kidney Medulla; LLC-PK1 Cells; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Swine; Thiazoles; Tissue Distribution; Toluene; Tumor Suppressor Protein p53 | 2003 |
Structural basis for contrasting activities of ribosome binding thiazole antibiotics.
Topics: Anti-Bacterial Agents; Bacteriocins; Base Sequence; Binding Sites; Guanosine Triphosphate; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Methyltransferases; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Ribosomes; RNA, Ribosomal, 23S; Thiazoles; Thiostrepton | 2003 |
Effects of the antibiotic pulvomycin on the elongation factor Tu-dependent reactions. Comparison with other antibiotics.
Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Enzyme Inhibitors; Enzyme Stability; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Peptide Elongation Factor Tu; Peptide Elongation Factors; Peptides, Cyclic; Protein Denaturation; Pyridones; Thiazoles; Trypsin; Urea | 2004 |
Protective effect of green tea polyphenols on the SH-SY5Y cells against 6-OHDA induced apoptosis through ROS-NO pathway.
Topics: Annexin A5; Apoptosis; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; Free Radicals; Guanosine Triphosphate; Humans; Membrane Potentials; Mitochondria; Models, Biological; Neurons; Nitric Oxide; Oxidopamine; Oxygen; Parkinson Disease; Phenols; Polyphenols; Quinones; Reactive Oxygen Species; Tea; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine | 2005 |
Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin.
Topics: Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, Liquid; Colchicine; Docetaxel; Guanosine Triphosphate; Linear Models; Paclitaxel; Podophyllotoxin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Taxoids; Thiazoles; Tubulin; Tubulin Modulators; Vinblastine; Vincristine | 2010 |
Characterization of Caulobacter crescentus FtsZ protein using dynamic light scattering.
Topics: Algorithms; Bacterial Proteins; Caulobacter crescentus; Cytoskeletal Proteins; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Light; Microscopy, Electron, Transmission; Protein Multimerization; Protein Stability; Pyridines; Scattering, Radiation; Solutions; Thiazoles | 2012 |
Identification of a novel antiviral inhibitor of the flavivirus guanylyltransferase enzyme.
Topics: Antiviral Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavivirus; Guanosine Triphosphate; High-Throughput Screening Assays; Humans; Microbial Sensitivity Tests; Nucleotidyltransferases; Structure-Activity Relationship; Thiazoles; Viral Nonstructural Proteins | 2012 |
(-)-Epicatechin gallate prevents alkali-salt mediated fibrillogenesis of hen egg white lysozyme.
Topics: Alkalies; Animals; Benzothiazoles; Catechin; Chickens; Circular Dichroism; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Microscopy, Fluorescence; Muramidase; Nephelometry and Turbidimetry; Protein Structure, Secondary; Salts; Thiazoles; Time Factors; Tryptophan | 2013 |
Identifying ligand-binding hot spots in proteins using brominated fragments.
Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Escherichia coli; Gene Expression; Guanosine Triphosphate; Halogenation; Ligands; Mass Spectrometry; Molecular Docking Simulation; Peptide Elongation Factor Tu; Peptide Mapping; Peptides, Cyclic; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; RNA, Transfer; Small Molecule Libraries; Thermus thermophilus; Thiazoles | 2013 |
Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Disease Models, Animal; Guanosine Triphosphate; Humans; Inflammation; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lipopolysaccharides; Mice; Mice, Transgenic; Microglia; Mutation; Neurons; Parkinson Disease; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Sulfones; Thiazoles | 2014 |
Understanding nucleotide-regulated FtsZ filament dynamics and the monomer assembly switch with large-scale atomistic simulations.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Calcium; Cytoskeletal Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Ions; Magnesium; Methanocaldococcus; Molecular Dynamics Simulation; Nucleotides; Protein Conformation; Protein Stability; Pyridines; Static Electricity; Thiazoles; Video Recording | 2014 |