Page last updated: 2024-08-21

thiazoles and gdc 0449

thiazoles has been researched along with gdc 0449 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katagiri, S; Ohyashiki, K; Okabe, S; Tanaka, Y; Tauchi, T1
Luo, L; Ma, H; Sun, Z; Tian, S; Yang, Z; Zhang, X; Zheng, J1
Chen, X; Lin, L; Liu, S; Meng, W; Sun, C; Wang, R; Zang, W; Zhang, Y1

Other Studies

3 other study(ies) available for thiazoles and gdc 0449

ArticleYear
Effects of the hedgehog inhibitor GDC-0449, alone or in combination with dasatinib, on BCR-ABL-positive leukemia cells.
    Stem cells and development, 2012, Nov-01, Volume: 21, Issue:16

    Topics: Anilides; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Dasatinib; Feeder Cells; Hedgehog Proteins; Humans; Intracellular Space; Kruppel-Like Transcription Factors; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nuclear Proteins; Pyridines; Pyrimidines; RNA, Small Interfering; Signal Transduction; Thiazoles; Transcription Factors; Transfection; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2

2012
Discovery of a 6-(pyridin-3-yl)benzo[d]thiazole template for optimization of hedgehog and PI3K/AKT/mTOR dual inhibitors.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Anilides; Animals; Antineoplastic Agents; Drug Design; Drug Discovery; Drug Screening Assays, Antitumor; Hedgehog Proteins; Humans; Mice; Molecular Targeted Therapy; NIH 3T3 Cells; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Structure-Activity Relationship; Thiazoles; TOR Serine-Threonine Kinases

2015
Synthesis and Evaluation of Aminothiazole Derivatives as Hedgehog Pathway Inhibitors.
    Chemistry & biodiversity, 2019, Volume: 16, Issue:12

    Topics: Anilides; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Hedgehog Proteins; Mice; Pyridines; Signal Transduction; Thiazoles

2019