Page last updated: 2024-08-21

thiazoles and fp-tztp

thiazoles has been researched along with fp-tztp in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (10.53)	18.2507
2000's	16 (84.21)	29.6817
2010's	1 (5.26)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carson, RE; Der, MG; Eckelman, WC; Herscovitch, P; Jagoda, E; Kiesewetter, DO	1
Carson, RE; Eckelman, WC; Herscovitch, P; Jagoda, EM; Kiesewetter, DO	1
Eckelman, WC	2
Eckelman, WC; Huang, BX; Jagoda, EM; Kiesewetter, DO; Ma, Y	1
Channing, MA; Kiesewetter, DO; Vuong, BK	1
Bokde, A; Carson, RE; Cohen, RM; Connolly, C; Eckelman, WC; Herscovitch, P; Kiesewetter, DO; Podruchny, TA; Sunderland, T	1
Eckelman, WC; Gomeza, J; Jagoda, EM; Kiesewetter, DO; Ravasi, L; Shimoji, K; Wess, J; Yamada, M	1
Carson, RE; Der, M; Eckelman, WC; Huang, B; Kiesewetter, DO; Lang, L; Ma, Y	1
Bokde, AL; Carson, RE; Cohen, RM; Eckelman, WC; Herscovitch, P; Kiesewetter, DO; Podruchny, TA; Sunderland, T	1
Cook, M; Eckelman, WC; Esaki, T; Itoh, Y; Jagoda, EM; Jehle, J; Kiesewetter, DO; Ravasi, L; Schmidt, K; Shimoji, K; Sokoloff, L	1
Benson, BE; Carson, RE; Eckelman, WC; Herscovitch, P; Ketter, TA; Kiesewetter, DO; Post, RM	1
Eckelman, WC; Kiesewetter, DO; Lucignani, G; Ravasi, L; Shimoji, K	1
Carson, RE; Cohen, RM; Filbey, F; Sunderland, T; Szczepanik, J	1
Cannon, DM; Carson, RE; Drevets, M; Drevets, WC; Eckelman, WC; Gandhi, S; Kiesewetter, DO; Nugent, AC; Rollis, D; Solorio, G; Williams, J	1
Carson, RE; Cohen, RM; Ichise, M	1
Alexoff, D; Ding, YS; Eckelman, WC; Fowler, JS; Logan, J; Reid, AE; Shea, C; Xu, Y	1
Houle, S; Mamo, DC; Mulsant, BH; Pollock, BG; Stephenson, KA; van Oosten, EM; Vasdev, N; Wilson, AA; Yudin, AK	1
Eckelman, WC; Kiesewetter, DO; Nakayama, T; Ravasi, L; Seidel, J; Sokoloff, L; Tokugawa, J	1

Reviews

2 review(s) available for thiazoles and fp-tztp

Article	Year
Using single photon emission tomography (SPECT) and positron emission tomography (PET) to trace the distribution of muscarinic acetylcholine receptor (MACHR) binding radioligands. Life sciences, 1999, Volume: 64, Issue:6-7 Topics: Animals; Benzilates; Brain; Fluorine Radioisotopes; Heart; Humans; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Physostigmine; Pyridines; Quinuclidines; Radioactive Tracers; Receptors, Muscarinic; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1999
Accelerating drug discovery and development through in vivo imaging. Nuclear medicine and biology, 2002, Volume: 29, Issue:8 Topics: Animals; Drug Design; Drug Industry; Fluorine Radioisotopes; Humans; Isotope Labeling; Mice; Mice, Knockout; Pharmaceutical Preparations; Proteins; Pyridines; Radiopharmaceuticals; Receptors, Drug; Thiazoles; Tomography, Emission-Computed	2002

Article

Year

Using single photon emission tomography (SPECT) and positron emission tomography (PET) to trace the distribution of muscarinic acetylcholine receptor (MACHR) binding radioligands.

Life sciences, 1999, Volume: 64, Issue:6-7

Topics: Animals; Benzilates; Brain; Fluorine Radioisotopes; Heart; Humans; Ligands; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Physostigmine; Pyridines; Quinuclidines; Radioactive Tracers; Receptors, Muscarinic; Thiazoles; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1999

Accelerating drug discovery and development through in vivo imaging.

Nuclear medicine and biology, 2002, Volume: 29, Issue:8

Topics: Animals; Drug Design; Drug Industry; Fluorine Radioisotopes; Humans; Isotope Labeling; Mice; Mice, Knockout; Pharmaceutical Preparations; Proteins; Pyridines; Radiopharmaceuticals; Receptors, Drug; Thiazoles; Tomography, Emission-Computed

2002

Other Studies

17 other study(ies) available for thiazoles and fp-tztp

Article	Year
Muscarinic cholinergic receptor measurements with [18F]FP-TZTP: control and competition studies. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1998, Volume: 18, Issue:10 Topics: Acetylcholine; Anesthesia; Anesthetics, Inhalation; Animals; Binding, Competitive; Blood Proteins; Brain; Cholinesterase Inhibitors; Chromatography, Thin Layer; Fluorine Radioisotopes; Isoflurane; Kinetics; Macaca mulatta; Models, Neurological; Physostigmine; Pyridines; Receptors, Muscarinic; Thiazoles; Tomography, Emission-Computed	1998
Radiolabeled muscarinic radioligands for in vivo studies. Nuclear medicine and biology, 2001, Volume: 28, Issue:5 Topics: Alzheimer Disease; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Muscarinic Agonists; Pyridines; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Thiazoles	2001
Identification of metabolites of fluorine-18-labeled M2 muscarinic receptor agonist, 3-(3-[(3-fluoropropyl)thio]-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine, produced by human and rat hepatocytes. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jan-25, Volume: 766, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Fluorine; Hepatocytes; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Muscarinic Agonists; Pyridines; Rats; Rats, Sprague-Dawley; Thiazoles; Tomography, Emission-Computed	2002
The automated radiosynthesis of [18F]FP-TZTP. Nuclear medicine and biology, 2003, Volume: 30, Issue:1 Topics: Equipment Design; Fluorine Radioisotopes; Isotope Labeling; Pyridines; Quality Control; Radiopharmaceuticals; Robotics; Thiazoles; Tomography, Emission-Computed	2003
In vivo muscarinic 2 receptor imaging in cognitively normal young and older volunteers. Synapse (New York, N.Y.), 2003, Volume: 48, Issue:1 Topics: Acetylcholine; Adult; Aged; Aging; Brain; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Pyridines; Receptor, Muscarinic M2; Receptors, Muscarinic; Thiazoles; Tissue Distribution; Tomography, Emission-Computed	2003
Regional brain uptake of the muscarinic ligand, [18F]FP-TZTP, is greatly decreased in M2 receptor knockout mice but not in M1, M3 and M4 receptor knockout mice. Neuropharmacology, 2003, Volume: 44, Issue:5 Topics: Animals; Brain; Female; Fluorine Radioisotopes; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic; Thiazoles	2003
Determination of [18F]FCWAY, [18F]FP-TZTP, and their metabolites in plasma using rapid and efficient liquid-liquid and solid phase extractions. Nuclear medicine and biology, 2003, Volume: 30, Issue:3 Topics: Chromatography, Thin Layer; Humans; Ligands; Pyridines; Thiazoles; Tomography, Emission-Computed	2003
Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-epsilon4 allele. Synapse (New York, N.Y.), 2003, Sep-01, Volume: 49, Issue:3 Topics: Aged; Aging; Alleles; Apolipoprotein E4; Apolipoproteins E; Brain; Cerebrovascular Circulation; Female; Humans; Male; Middle Aged; Pyridines; Receptor, Muscarinic M2; Receptors, Muscarinic; Regional Blood Flow; Thiazoles; Tomography, Emission-Computed	2003
Inhibition of [18F]FP-TZTP binding by loading doses of muscarinic agonists P-TZTP or FP-TZTP in vivo is not due to agonist-induced reduction in cerebral blood flow. Synapse (New York, N.Y.), 2003, Volume: 50, Issue:2 Topics: Animals; Antipyrine; Atropine Derivatives; Binding, Competitive; Blood Pressure; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Fluorine Radioisotopes; Laser-Doppler Flowmetry; Male; Muscarinic Agonists; Pyridines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Thiadiazoles; Thiazoles	2003
A potential cholinergic mechanism of procaine's limbic activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:7 Topics: Anesthetics, Local; Animals; Autoradiography; Brain Mapping; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Inhibitory Concentration 50; Limbic System; Macaca mulatta; Male; Procaine; Pyridines; Radioligand Assay; Receptors, Muscarinic; Thiazoles; Tomography, Emission-Computed	2004
Why does the agonist [(18)F]FP-TZTP bind preferentially to the M(2) muscarinic receptor? European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:3 Topics: Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Fluorine Radioisotopes; Metabolic Clearance Rate; Organ Specificity; Protein Binding; Pyridines; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Sensitivity and Specificity; Thiazoles; Tissue Distribution	2006
Age and APOE-epsilon4 genotype influence the effect of physostigmine infusion on the in-vivo distribution volume of the muscarinic-2-receptor dependent tracer [18F]FP-TZTP. Synapse (New York, N.Y.), 2006, Volume: 60, Issue:1 Topics: Adult; Age Factors; Aged; Apolipoprotein E4; Apolipoproteins E; Brain; Cholinesterase Inhibitors; Female; Fluorine Radioisotopes; Genotype; Humans; Male; Middle Aged; Physostigmine; Positron-Emission Tomography; Pyridines; Receptor, Muscarinic M2; Thiazoles	2006
Reduced muscarinic type 2 receptor binding in subjects with bipolar disorder. Archives of general psychiatry, 2006, Volume: 63, Issue:7 Topics: Acetylcholine; Adult; Ambulatory Care; Bipolar Disorder; Brain; Depressive Disorder, Major; Female; Fluorodeoxyglucose F18; Gyrus Cinguli; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Pyridines; Radioligand Assay; Receptor, Muscarinic M2; Synapses; Thiazoles; Tissue Distribution	2006
Noninvasive estimation of normalized distribution volume: application to the muscarinic-2 ligand [(18)F]FP-TZTP. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:2 Topics: Aged; Algorithms; Apolipoproteins E; Brain; Computer Simulation; Female; Fluorine Radioisotopes; Humans; Male; Models, Statistical; Nonlinear Dynamics; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Receptor, Muscarinic M2; Reference Standards; Thiazoles	2008
Comparison of the pharmacokinetics of different analogs of 11C-labeled TZTP for imaging muscarinic M2 receptors with PET. Nuclear medicine and biology, 2008, Volume: 35, Issue:3 Topics: Animals; Area Under Curve; Binding, Competitive; Brain; Carbon Radioisotopes; Drug Agonism; Fluorine Radioisotopes; Metabolic Clearance Rate; Mice; Papio; Positron-Emission Tomography; Pyridines; Radioligand Assay; Receptor, Muscarinic M2; Structure-Activity Relationship; Thiadiazoles; Thiazoles; Tissue Distribution	2008
An improved radiosynthesis of the muscarinic M2 radiopharmaceutical, [18F]FP-TZTP. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2009, Volume: 67, Issue:4 Topics: Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pyridines; Radiopharmaceuticals; Receptor, Muscarinic M2; Thiazoles	2009
Imaging of the muscarinic acetylcholine neuroreceptor in rats with the M2 selective agonist [18F]FP-TZTP. Nuclear medicine and biology, 2012, Volume: 39, Issue:1 Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Autoradiography; Brain; Fluorine Radioisotopes; Isoflurane; Male; Positron-Emission Tomography; Pyridines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Thiazoles; Tissue Distribution	2012