Page last updated: 2024-08-21

thiazoles and fluorouracil

thiazoles has been researched along with fluorouracil in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.08)	18.7374
1990's	19 (19.79)	18.2507
2000's	33 (34.38)	29.6817
2010's	35 (36.46)	24.3611
2020's	7 (7.29)	2.80

Authors

Authors	Studies
Alburn, HE; Fenichel, RL; Gregory, FJ	1
Hotta, T; Iwahashi, M; Iwakura, S; Noguchi, K; Tamai, M; Tani, M; Tanimura, H; Tsunoda, T; Yamaue, H	1
Greve, EL; Nuyts, RM; Pels, E	1
Hisatsugu, T; Katano, M; Matsunaga, H; Morita, H; Oogushi, K; Sunaga, T; Yamamoto, H	1
Senderoff, RI; Smith, DR; Sokoloski, TD; Weber, PA	1
Furukawa, T; Ishibiki, K; Kase, S; Kitajima, M; Kodaira, S; Kubota, T; Kuo, TH; Nishibori, H; Saikawa, Y; Watanabe, M	1
Endo, Y; Kimura, H; Kinoshita, K; Miyazaki, I; Ninomiya, I; Ohyama, S; Sasaki, T; Tanaka, M; Tugawa, K; Yonemura, Y	1
Furukawa, T; Ishibiki, K; Kase, S; Kodaira, S; Kubota, T; Suto, A; Takahara, T; Takeuchi, T; Yamaguchi, H	1
Deguchi, T; Mataki, Y; Naya, M; Noguchi, M; Yasuda, M	1
Ishimura, H; Sasaki, F; Takada, N; Uchino, J	1
Kawahara, M; Kayada, Y; Munakata, H; Sakamoto, T; Takada, K; Yoshiga, K	1
King, WW; Lam, PK; Li, AK	1
Furukawa, T; Ishibiki, K; Kitajima, M; Kubota, T; Kumai, K; Saikawa, Y; Suto, A; Watanabe, M	1
Furukawa, T; Hoffman, RM; Kitajima, M; Kubota, T; Watanabe, M	1
Furukawa, T; Ishibiki, K; Kase, S; Kodaira, S; Kubota, T; Takahara, T; Takeuchi, T; Teramoto, T; Watanabe, M; Yamaguchi, H	1
Furukawa, T; Kitajima, M; Kubota, T	1
Haisa, M; Hatano, H; Naomoto, Y; Oka, Y; Orita, K; Tanaka, N; Yasuoka, Y	1
Hamaguchi, Y; Hasegawa, S; Hisatomi, H; Ichikawa, Y; Ishikawa, T; Kamiyama, M; Momiyama, N; Narita, T; Shimada, H	1
Fujii, M; Imai, S; Mochizuki, F	1
Song, S; Tang, Z; Xu, J	1
Fukushima, M; Ishikawa, Y; Kitajima, M; Kubota, T; Kumai, K; Okabe, H; Otani, Y; Takechi, T; Teramoto, T; Watanabe, M	1
Horowitz, D; King, AG	1
Els, WJ; Santos, AS; Truter, EJ	1
Mahyar-Roemer, M; Roemer, K	1
Aoyagi, S; Fukuda, S; Furukawa, S; Kinoshita, H; Okuda, K	1
Goberdhan, A; Hoffman, RM; Li, R; Patel, S; Pfister, D; Poluri, A; Shah, J; Shaha, AR; Sherman, E; Singh, B; Xu, L	1
Kaminishi, M; Kusada, O; Mochizuki, Y; Shimoyama, S	1
Adachi, Y; Hamada, H; Ichikawa, T; Kambara, H; Ohmoto, T; Ohtsuka, S; Ono, Y; Tamiya, T; Terada, K	1
Fukushima, M; Miki, T; Mizutani, Y; Nakao, M; Nonomura, M; Wada, H; Yoshida, O	1
Belinsky, MG; Chen, ZS; Guo, Y; Hopper-Borge, E; Kotova, E; Kruh, GD; Lee, K	1
CRANSTON, EM	1
Cvitkovic, E; Koeppel, F; Larsen, AK; Poindessous, V; Raymond, E; Waters, SJ	1
Gunduz, M; Haisa, M; Kawashima, R; Kimura, M; Nagai, N; Naomoto, Y; Shirakawa, Y; Takaoka, M; Takeda, H; Tanaka, N; Uetsuka, H	1
Emura, T; Fukushima, M; Kitazato, K; Murakami, Y; Nakagawa, F	1
Chang, HJ; Hong, SH; Jeon, E; Park, JG; Shin, YK; Yoo, BC	1
Alaoui-Jamali, MA; Chow, TY; Griller, D; Yeh, C; Yuen, L	1
Bi, F; Fan, D; Liu, N; Pan, Y; Shi, Y; Sun, L; Xue, Y; Yao, X; Zheng, Y	1
Alsina, M; Beam, C; Beaupre, DM; Dalton, W; Gerbino, E; Hamilton, AD; Kerr, WG; Lichtenheld, MG; Mackley, PA; Muro-Cacho, C; Sebti, SM; Zhu, K	1
Kitai, R; Kubota, T; Matsukawa, S; Sato, K; Takeuchi, H; Yao, Y	1
Bekaii-Saab, TS; Chen, CS; Li, J; Melvin, WS; Muscarella, P; Zhu, J	1
Feng, LF; Lei, XY; Liao, DF; Tang, SS; Zhong, M; Zhu, BY	1
Cai, C; Wu, L; Wu, Y; Zhou, K	1
Kitajima, Y; Koga, Y; Miyazaki, K; Miyoshi, A; Sato, K	1
Curtiss, FR	1
Ding, H; Ge, HM; Jiao, RH; Liu, JY; Tan, RX; Xu, C; Xu, S; Zhu, HL	1
Bongso, A; Gauthaman, K; Richards, M; Wong, J	1
Dietrich, J; Han, R; Luebke, A; Mayer-Pröschel, M; Noble, M; Yang, YM	1
Bevilacqua, G; Boggi, U; Campani, D; Danesi, R; Del Chiaro, M; Del Tacca, M; Funel, N; Giovannetti, E; Mey, V; Mosca, F; Nannizzi, S; Pollina, LE; Ricciardi, S	1
Ding, Y; Hua, W; Liu, J; Ran, Q; Shen, M; Wang, L; Wang, Z; Wu, X; Xu, J; Yang, J; Yuan, S; Zhang, L	1
Cui, J; Guo, YH; Li, CL; Nan, KJ; Tian, T; Wang, J; Zhang, WG; Zhao, N	1
Fukushima, M; Konishi, K; Okada, M; Sanada, Y; Tsutani, Y; Wada, Y; Yoshida, K	1
Gao, FY; He, JQ; Huang, CJ; Lv, SQ; Yang, H; Yin, CL; Zhang, EE; Zhang, KB	1
Gong, C; Guo, C; Lin, W; Liu, C; Liu, W	1
Che, XM; He, DL; Pan, CE; Wang, GR; Wang, XY; Wu, KJ; Zeng, J; Zhao, JH; Zheng, Y	1
Li, HQ; Ruan, XM; Shi, L; Xu, SP; Yang, Y; Zhu, HL; Zhu, ZW	1
Borden, E; Cao, M; Fan, K; Gerson, S; Kundu, S; Lindner, DJ; Liu, L; Tuthill, R; Yi, T	1
He, G; He, ZY; Hou, SX; Li, JM; Li, SZ; Luo, X; Luo, YF; Song, XR; Wei, YQ; Yang, L; Yu, S; Zheng, Y	1
Dai, W; Li, HY; Liu, YQ; Yang, L	1
Allen, JE; Brown, JM; Daniel, CJ; Dicker, DT; Dolloff, NG; Dorsey, JF; El-Deiry, WS; Furth, EE; Hart, LS; Jee, DI; Klein, PS; Kuribayashi, K; Liu, JJ; Liu, YY; Mayes, PA; Sears, RC	1
Li, F; Li, PD; Simayi, D; Wang, YH; Yuan, J; Zhang, HY; Zhang, WJ; Zhang, Y	1
Cianchetti, M; Forastiere, A; Gunn, GB; Marur, S; McNutt, T; Rao, N; Ricchetti, F; Sanguineti, G; Sormani, MP; Wu, B	1
Cabrera, BL; Carethers, JM; Iwaizumi, M; Tajima, A; Tseng-Rogenski, S	1
Hu, N; Lei, XY; Tang, HF; Xiang, Q; Yang, XY; Yin, J; Yu, J	1
Chen, WL; Guo, SR; Lei, L; Rong, HJ; Shen, YY	1
Hassanzadeh, F; Khadem, M; Sadeghi, H; Varshosaz, J	1
Knecht, R; Kurzweg, T; Laban, S; Möckelmann, N	1
Dalirsani, Z; Farajnia, S; Javadzadeh, Y; Koozegari, S; Mehdipour, M	1
Covell, DG	1
Chen, KL; Hu, JK; Li, Y; Liu, Y; Meng, WJ; Sun, XF; Yang, L; Zhang, W; Zhou, B; Zhou, ZG	1
Atzori, F; Cortes, J; Geese, WJ; Gradishar, WJ; Rybicki, A; Somlo, G; Specht, JM; Strauss, LC; Sy, O; Vahdat, LT	1
Chen, M; Chen, W; Cheung, WL; Chow, A; Chu, C; Lam, S; Lau, T; Li, Y; Ng, L; Nie, Y; Pang, R; Wong, BC; Zhang, X	1
Kabadere, S; Kus, G; Oztopcu-Vatan, P; Uyar, R	1
Chen, D; Jiao, XL; Liu, ZK; Niu, M; Zhang, MS	1
Arrowood, C; Blobe, GC; Brady, JC; Cohn, A; Haley, S; Hsu, SD; Hurwitz, HI; McCall, S; Meadows, KL; Morse, MA; Nixon, AB; Pang, H; Rushing, C; Starodub, A; Strickler, JH; Uronis, HE; Zafar, SY	1
An, J; Chen, YY; Lan, Y; Liu, N; Mao, YQ; Wang, Q; Wang, WP; Wu, Q; Zhang, YW; Zhao, BC	1
Chen, X; Dai, H; Qian, Z; Wang, Y; Xu, X; Zhao, Y	1
Lei, X; Tang, H; Xiang, Q; Yang, X; Yin, J; Yu, J; Zhang, P	1
Enoki, T; Hamano, K; Hosoyama, T; Kugimiya, N; Li, TS; Nishimoto, A; Ueno, K	1
Hartinger, J; Matoušková, E; Netíková, I; Petruželka, L; Veselý, P	1
Bajrektarević, D; Filipič, M; Gajski, G; Garaj-Vrhovac, V; Gerić, M; Novak, M; Nunić, J; Žegura, B	1
Hu, Y; Li, H; Peng, L; Xu, S; Yang, G; Zhao, Y	1
Bu, LL; Gutkind, JS; Huang, CF; Kulkarni, AB; Liu, B; Liu, JF; Ma, SR; Sun, ZJ; Yu, GT; Zhang, L; Zhang, WF; Zhao, ZL	1
Chang, L; Li, Q; Liu, W; Liu, Y; Lv, Y; Song, L; Zhang, X; Zhou, X	1
Liu, H; Ma, C; Wang, J; Wang, K; Wu, K; Xia, K	1
Du, B; Liu, J; Tan, Y; Wu, Y; Wu, Z; Zeng, X; Zhang, G; Zhang, R; Zhang, W; Zhang, X; Zhao, Y	1
Grbčić, P; Klobučar, M; Kraljević Pavelić, S; Lučin, K; Sedić, M; Tomljanović, I	1
Alipour, B; Faghfoori, Z; Mousavi Jam, A; Saber, A; Yari Khosroushahi, A	1
Hirai, A; Ichiki, Y; Imanishi, N; Ishida, T; Kusanagi, K; Shinohara, S; Takeda, Y; Tanaka, F; Tashima, Y; Yoshimatsu, K	1
Jimi, S; Kamei, T; Oohata, Y; Takahata, S; Tamura, T	1
Alazragi, R; El-Sherbeeny, NA; Elaidy, SM; Helmi, N; Salem, N; Tantawy, MA	1
Chen, Y; Gao, D; Kong, F; Lin, Y; Lin, Z; Miao, J; Wang, P; Wang, Z; Zhang, L; Zhang, M; Zhao, B; Zhou, X	1
Anwar, N; Khan, S	1
Bosco, B; Calheiros, J; Carvalho, ATP; Chlapek, P; Domingues, L; Fabian, P; Gomes, C; Inga, A; Monteiro, FA; Nunes, C; Piazza, S; Pinho E Melo, TMVD; Raimundo, L; Rajado, AT; Ramos, H; Reis, F; Reis, S; Saraiva, L; Silva, J; Soares, MIL; Veselska, R; Vlcek, P	1
Duarte, D; Vale, N	1
Abbas, AA; Dawood, KM; Mohamed, BE; Nafie, MS; Raslan, MA	1
Dhaduk, BB; Hadiyal, SD; Joshi, HS; Lalpara, JN	1

Reviews

1 review(s) available for thiazoles and fluorouracil

Article	Year
Current treatment options for recurrent/metastatic head and neck cancer: a post-ASCO 2011 update and review of last year's literature. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:10 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Dasatinib; ErbB Receptors; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Indoles; Neoplasm Recurrence, Local; Palliative Care; Pyrimidines; Pyrroles; Quinazolines; Quinazolinones; Salvage Therapy; Squamous Cell Carcinoma of Head and Neck; Sunitinib; Thiazoles	2012

Article

Year

Current treatment options for recurrent/metastatic head and neck cancer: a post-ASCO 2011 update and review of last year's literature.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:10

Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Dasatinib; ErbB Receptors; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Indoles; Neoplasm Recurrence, Local; Palliative Care; Pyrimidines; Pyrroles; Quinazolines; Quinazolinones; Salvage Therapy; Squamous Cell Carcinoma of Head and Neck; Sunitinib; Thiazoles

2012

Trials

2 trial(s) available for thiazoles and fluorouracil

Article	Year
Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004. Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-01, Volume: 19, Issue:7 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Capecitabine; Dasatinib; Deoxycytidine; Female; Fluorouracil; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pyrimidines; Thiazoles; Treatment Outcome	2013
Phase I study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer. Investigational new drugs, 2014, Volume: 32, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Colorectal Neoplasms; Dasatinib; Deoxycytidine; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles; Vascular Endothelial Growth Factor A	2014

Article

Year

Dasatinib plus capecitabine for advanced breast cancer: safety and efficacy in phase I study CA180004.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Apr-01, Volume: 19, Issue:7

Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Capecitabine; Dasatinib; Deoxycytidine; Female; Fluorouracil; Humans; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Pyrimidines; Thiazoles; Treatment Outcome

2013

Phase I study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer.

Investigational new drugs, 2014, Volume: 32, Issue:2

Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Colorectal Neoplasms; Dasatinib; Deoxycytidine; Female; Fluorouracil; Humans; Male; Maximum Tolerated Dose; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles; Vascular Endothelial Growth Factor A

2014

Other Studies

93 other study(ies) available for thiazoles and fluorouracil

Article	Year
Anti-tumour and anti-metastatic activity of 3-(P-Chlorophenyl)-2,3-Dihydro-3-Hydroxythiazolo (3,2-A)-Benzimidazole-2-acetic acid (WY-13,876). British journal of cancer, 1976, Volume: 33, Issue:3 Topics: Animals; Anthelmintics; Antilymphocyte Serum; Antineoplastic Agents; Benzimidazoles; Cyclophosphamide; Fluorouracil; Lethal Dose 50; Levamisole; Lung Neoplasms; Male; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; T-Lymphocytes; Thiazoles; Transplantation, Isogeneic	1976
Chemosensitivity testing of fresh human gastric cancer with highly purified tumour cells using the MTT assay. British journal of cancer, 1992, Volume: 66, Issue:5 Topics: Adult; Aged; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1992
The effects of 5-fluorouracil and mitomycin C on the corneal endothelium. Current eye research, 1992, Volume: 11, Issue:6 Topics: Animals; Cattle; Cell Survival; Cells, Cultured; Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Endothelium, Corneal; Fluorouracil; Mitomycin; Tetrazolium Salts; Thiazoles; Time Factors	1992
[Strategy for therapy of malignant ascites using MTT assay]. Gan to kagaku ryoho. Cancer & chemotherapy, 1992, Volume: 19, Issue:6 Topics: Antineoplastic Agents; Ascitic Fluid; Breast Neoplasms; Cisplatin; Clinical Protocols; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1992
Evaluation of antiproliferative agents using a cell-culture model. Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:12 Topics: Animals; Bleomycin; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Cricetinae; Cytarabine; Drug Evaluation, Preclinical; Floxuridine; Fluorouracil; Tetrazolium Salts; Thiazoles; Time Factors; Uridine	1990
Increased drug resistance of cultured human cancer cell lines in three-dimensional cellular growth assay using collagen gel matrix. Journal of surgical oncology, 1992, Volume: 49, Issue:2 Topics: Adenocarcinoma; Antineoplastic Agents; Cisplatin; Collagen; Colonic Neoplasms; Culture Media; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1992
[Chemosensitivity test for gastric cancer by in vitro MTT assay]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:10 Topics: Antineoplastic Agents; Carbazilquinone; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Mitomycin; Mitomycins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1991
[Establishment of transplantable human colon cancer cell lines, chemosensitivity of colon carcinomas and the serially transplantable strains with MTT assay]. Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:13 Topics: Animals; Antineoplastic Agents; Cisplatin; Colonic Neoplasms; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1991
Effects of L-2-oxothiazolidine-4-carboxylate, a cysteine pro-drug, on teratogenicity of 5-fluorouracil in mice. Hiroshima journal of medical sciences, 1990, Volume: 39, Issue:3 Topics: Animals; Body Weight; Cystine; Drug Synergism; Female; Fluorouracil; Glutathione; Limb Deformities, Congenital; Liver; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Pregnancy; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines	1990
[Chemosensitivity test for thyroid cancer by in vitro MTT assay]. Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:12 Topics: Antineoplastic Agents; Cisplatin; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Male; Middle Aged; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured	1995
A biochemical evaluation of oral squamous cell carcinoma growth by measurement of specific activity of succinate dehydrogenase in the subrenal capsule assay. International journal of oral and maxillofacial surgery, 1995, Volume: 24, Issue:3 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Colorimetry; Coloring Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Peplomycin; Regression Analysis; Subrenal Capsule Assay; Succinate Dehydrogenase; Tetrazolium Salts; Thiazoles	1995
Anti-proliferative activity of interferon-alpha on human squamous carcinoma of tongue cell lines. Cancer letters, 1994, Sep-30, Volume: 85, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Cisplatin; Combined Modality Therapy; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Interferon Type I; Kinetics; Recombinant Proteins; Tetrazolium Salts; Thiazoles; Tongue Neoplasms; Tumor Cells, Cultured	1994
Single-cell suspension assay with an MTT end point is useful for evaluating the optimal adjuvant chemotherapy for advanced gastric cancer. Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:7 Topics: Adult; Aged; Chemotherapy, Adjuvant; Cisplatin; Coloring Agents; Doxorubicin; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; In Vitro Techniques; Male; Middle Aged; Mitomycin; Neoplasm Staging; Stomach Neoplasms; Survival Rate; Tetrazolium Salts; Thiazoles	1994
A novel "patient-like" treatment model of human pancreatic cancer constructed using orthotopic transplantation of histologically intact human tumor tissue in nude mice. Cancer research, 1993, Jul-01, Volume: 53, Issue:13 Topics: Animals; Disease Models, Animal; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitomycin; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Tetrazolium Salts; Thiazoles; Transplantation, Heterologous	1993
The modulation by L-leucovorin of 5-fluorouracil antitumor activity on human colon carcinoma cells in vitro and in vivo. Surgery today, 1993, Volume: 23, Issue:7 Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Infusions, Parenteral; Leucovorin; Male; Mice; Mice, Inbred Strains; Mice, Nude; Models, Biological; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured	1993
[High clinical predictability of histoculture drug response assay (HDRA) for drug-sensitivity of cancer of the digestive organs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:4 Topics: Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Mitomycin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1993
Apoptosis in cultured human colon cancer cells induced by combined treatments with 5-fluorouracil, tumor necrosis factor-alpha and interferon-alpha. Japanese journal of clinical oncology, 1997, Volume: 27, Issue:4 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azure Stains; Cell Survival; Colonic Neoplasms; Coloring Agents; DNA Nucleotidylexotransferase; Fluorouracil; Humans; Interferon-alpha; Methyl Green; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1997
Telomerase enzyme activity and RNA expression in adriamycin-resistant human breast carcinoma MCF-7 cells. Cancer letters, 1999, Jul-01, Volume: 141, Issue:1-2 Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinoma; Cell Count; Cell Division; Cell Survival; Docetaxel; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Female; Fluorouracil; Gene Expression; Humans; Paclitaxel; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Taxoids; Telomerase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	1999
[Comparative study of histopathological effects of preoperative chemotherapy using UFT and in vitro MTT assay of colonoscopy specimens from patients with colorectal cancer]. Gan to kagaku ryoho. Cancer & chemotherapy, 1999, Volume: 26, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Colonoscopy; Colorectal Neoplasms; Drug Administration Schedule; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Tegafur; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Uracil	1999
[Predictive chemotherapy of breast cancer directed by MTT assay in vitro]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 1997, Volume: 19, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Coloring Agents; Cyclophosphamide; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; Methotrexate; Prospective Studies; Tetrazolium Salts; Thiazoles	1997
Dihydropyrimidine dehydrogenase and messenger RNA levels in gastric cancer: possible predictor for sensitivity to 5-fluorouracil. Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:1 Topics: Antimetabolites, Antineoplastic; Biopsy; Coloring Agents; Dihydrouracil Dehydrogenase (NADP); Drug Resistance, Neoplasm; Fluorouracil; Humans; Oxidoreductases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Thymidylate Synthase	2000
Colorimetric determination of inhibition of hematopoietic progenitor cells in soft agar. Journal of immunological methods, 2000, Oct-20, Volume: 244, Issue:1-2 Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Colony-Forming Units Assay; Colony-Stimulating Factors; Colorimetry; Coloring Agents; Cytarabine; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluorouracil; Ganciclovir; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Tetrazolium Salts; Thiazoles; Zidovudine	2000
Assessment of the antitumour activity of targeted immunospecific albumin microspheres loaded with cisplatin and 5-fluorouracil: toxicity against a rodent ovarian carcinoma in vitro. Cell biology international, 2001, Volume: 25, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Fluorouracil; Humans; Microspheres; Ovarian Neoplasms; Rats; Serum Albumin; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured	2001
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene, 2001, Jun-07, Volume: 20, Issue:26 Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2001
[Examination of in vitro chemosensitivity test using methylthiazole tetrazolium bromide chemosensitivity (MTT) test with combined drugs in hepatic arterial infusion chemotherapy for carcinoma of the liver]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Coloring Agents; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Mice; Mice, Nude; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured	2001
Prediction of survival in patients with head and neck cancer using the histoculture drug response assay. Head & neck, 2002, Volume: 24, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Survival; Cisplatin; Drug Monitoring; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Male; Middle Aged; Survival Rate; Tetrazolium Salts; Thiazoles; Time Factors; Treatment Outcome	2002
Supra-additive antitumor activity of 5FU with tumor necrosis factor-related apoptosis-inducing ligand on gastric and colon cancers in vitro. International journal of oncology, 2002, Volume: 21, Issue:3 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Cell Division; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; HT29 Cells; Humans; Membrane Glycoproteins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	2002
Combined radiation and gene therapy for brain tumors with adenovirus-mediated transfer of cytosine deaminase and uracil phosphoribosyltransferase genes. Cancer gene therapy, 2002, Volume: 9, Issue:10 Topics: Adenoviridae; Animals; Apoptosis; Brain; Brain Neoplasms; Cell Division; Combined Modality Therapy; Cytosine Deaminase; Flow Cytometry; Fluorouracil; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Lac Operon; Male; Nucleoside Deaminases; Pentosyltransferases; Radiotherapy; Rats; Rats, Wistar; Survival Rate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured	2002
Significance of thymidylate synthase activity in renal cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Renal Cell; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dihydrouracil Dehydrogenase (NADP); Disease Progression; Female; Fluorouracil; Humans; Kidney; Kidney Neoplasms; Male; Middle Aged; Protein Binding; Pyrimidines; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Time Factors	2003
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine. The Journal of biological chemistry, 2003, Aug-08, Volume: 278, Issue:32 Topics: Adenine; Adenosine Triphosphate; Animals; Antineoplastic Agents; Antiviral Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cell Membrane; Colforsin; Coloring Agents; Cyclic AMP; Cyclic GMP; DNA, Complementary; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Fluorouracil; Genetic Vectors; Growth Inhibitors; Immunoblotting; Inhibitory Concentration 50; Insecta; Models, Biological; Nitrosamines; Nucleotides; Organophosphonates; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Zalcitabine	2003
Ineffectiveness of five compounds on spontaneous mammary tumors of mice. Cancer chemotherapy reports, 1963, Volume: 27 Topics: Animals; Chlorprothixene; Fluorouracil; Hydrocarbons; Mammary Neoplasms, Animal; Mice; Naphthoquinones; Neoplasms; Neoplasms, Experimental; Thiazoles	1963
Enhanced antitumor activity of irofulven in combination with 5-fluorouracil and cisplatin in human colon and ovarian carcinoma cells. International journal of oncology, 2003, Volume: 23, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Inhibitory Concentration 50; Models, Chemical; Ovarian Neoplasms; Sesquiterpenes; Tetrazolium Salts; Thiazoles	2003
Cyclin A correlates with the sensitivity of human cancer cells to cytotoxic effects of 5-FU. International journal of oncology, 2004, Volume: 24, Issue:2 Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Line, Tumor; Collagen; Colonic Neoplasms; Coloring Agents; Cyclin A; Dose-Response Relationship, Drug; Flow Cytometry; Fluorouracil; Humans; Immunoblotting; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; S Phase; Tetrazolium Salts; Thiazoles; Time Factors	2004
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells. International journal of molecular medicine, 2004, Volume: 13, Issue:4 Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; Coloring Agents; Drug Combinations; Drug Resistance, Neoplasm; Fluorouracil; Globins; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Polymerase Chain Reaction; Pyrrolidines; Sensitivity and Specificity; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Thymine; Trifluridine; Uracil	2004
Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1 Topics: Amino Acids; Aminobutyrates; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Agonists; Fluorouracil; Humans; Ligands; Organophosphonates; Receptors, Metabotropic Glutamate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Time Factors	2004
The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer. Molecular cancer therapeutics, 2004, Volume: 3, Issue:8 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; DNA; DNA Damage; DNA Repair; Down-Regulation; Drug Evaluation, Preclinical; Endonucleases; Etoposide; Exonucleases; Fluorouracil; HeLa Cells; Humans; Kinetics; Mice; Mitomycin; Neoplasms; Pentamidine; Plasmids; Recombination, Genetic; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors	2004
Reversal of the malignant phenotype of gastric cancer cells by inhibition of RhoA expression and activity. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Sep-15, Volume: 10, Issue:18 Pt 1 Topics: Agar; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Differentiation; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; DNA; Dose-Response Relationship, Drug; Doxorubicin; Epithelial Cells; Flow Cytometry; Fluorouracil; Genes, Dominant; Humans; Immunohistochemistry; Mice; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides; Phenotype; rhoA GTP-Binding Protein; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Time Factors; Transfection; Wound Healing	2004
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood, 2005, Jun-15, Volume: 105, Issue:12 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bone Marrow Cells; Caspase 3; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Cisplatin; Clinical Trials as Topic; Cytochromes c; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Enzyme Activation; Farnesyltranstransferase; Flow Cytometry; Fluorouracil; G2 Phase; Gemcitabine; Homozygote; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Mice; Mice, SCID; Mitosis; Multiple Myeloma; Paclitaxel; Quinolones; Taxoids; Tetrazolium Salts; Thiazoles	2005
Interferons upregulate thymidine phosphorylase expression via JAK-STAT-dependent transcriptional activation and mRNA stabilization in human glioblastoma cells. Journal of neuro-oncology, 2005, Volume: 72, Issue:3 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; Glioblastoma; Half-Life; Humans; Indicators and Reagents; Interferons; Janus Kinase 1; Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger; STAT1 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine Phosphorylase; Trans-Activators; Transcriptional Activation; Up-Regulation	2005
A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fluorouracil; Gemcitabine; Humans; Pancreatic Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Ribonucleotide Reductases; Sulfonamides; Tetrazolium Salts; Thiazoles	2006
Bcl-2 siRNA induced apoptosis and increased sensitivity to 5-fluorouracil and HCPT in HepG2 cells. Journal of drug targeting, 2006, Volume: 14, Issue:1 Topics: Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Caspase 3; Caspases; Cell Line, Tumor; Drug Delivery Systems; Drug Synergism; Flow Cytometry; Fluorouracil; Genes, bcl-2; Humans; Liver Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tetrazolium Salts; Thiazoles	2006
Enhanced liver targeting of 5-fluorouracil using galactosylated human serum albumin as a carrier molecule. Journal of drug targeting, 2006, Volume: 14, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Female; Fluorouracil; Galactose; Humans; Iodine Radioisotopes; Isotope Labeling; Liver; Male; Mice; Rabbits; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetrazolium Salts; Thiazoles; Tissue Distribution	2006
Deficient expression of the DPD gene is caused by epigenetic modification in biliary tract cancer cells, and induces high sensitivity to 5-FU treatment. International journal of oncology, 2006, Volume: 29, Issue:2 Topics: Antimetabolites, Antineoplastic; Base Sequence; Biliary Tract Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Epigenesis, Genetic; Fluorouracil; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Sequence Data; Protein Synthesis Inhibitors; Tetrazolium Salts; Thiazoles	2006
Pharmacy benefit spending on oral chemotherapy drugs. Journal of managed care pharmacy : JMCP, 2006, Volume: 12, Issue:7 Topics: Administration, Oral; Ambulatory Care; Antineoplastic Agents; Benzamides; Benzenesulfonates; Capecitabine; Dasatinib; Deoxycytidine; Drug Costs; Employer Health Costs; Erlotinib Hydrochloride; Fluorouracil; Gefitinib; Health Benefit Plans, Employee; Humans; Imatinib Mesylate; Indoles; Insurance, Pharmaceutical Services; Lenalidomide; Neoplasms; Niacinamide; Phenylurea Compounds; Piperazines; Prescription Fees; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Sorafenib; Sunitinib; Thalidomide; Thiazoles; United States	2006
Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015. Organic letters, 2006, Dec-07, Volume: 8, Issue:25 Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Campanulaceae; Cell Line, Tumor; Chaetomium; Circular Dichroism; Colonic Neoplasms; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Indole Alkaloids; K562 Cells; Magnetic Resonance Spectroscopy; Plant Leaves; Spectrometry, Mass, Electrospray Ionization; Tetrazolium Salts; Thiazoles	2006
Comparative evaluation of the effects of statins on human stem and cancer cells in vitro. Reproductive biomedicine online, 2007, Volume: 15, Issue:5 Topics: Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Embryonic Stem Cells; Fluorouracil; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Phase-Contrast; Polymerase Chain Reaction; Terpenes; Tetrazolium Salts; Thiazoles	2007
Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system. Journal of biology, 2008, Volume: 7, Issue:4 Topics: Action Potentials; Animals; Antineoplastic Agents; Auditory Pathways; Bromodeoxyuridine; Cell Line, Tumor; Central Nervous System; Fluorouracil; Humans; In Situ Nick-End Labeling; Indoles; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Myelin Sheath; Rats; Stem Cells; Tetrazolium Salts; Thiazoles	2008
Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma. Laboratory investigation; a journal of technical methods and pathology, 2008, Volume: 88, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cells, Cultured; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Lasers; Male; Microdissection; Middle Aged; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; RNA, Messenger; Tetrazolium Salts; Thiazoles	2008
Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates. Bioorganic & medicinal chemistry letters, 2008, Aug-15, Volume: 18, Issue:16 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Diterpenes, Kaurane; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; HL-60 Cells; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles	2008
Survival advantages of multicellular spheroids vs. monolayers of HepG2 cells in vitro. Oncology reports, 2008, Volume: 20, Issue:6 Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Line, Tumor; Cell Survival; Cisplatin; Doxorubicin; Fluorouracil; Humans; Hyaluronan Receptors; In Vitro Techniques; Spheroids, Cellular; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2008
Decreased orotate phosphoribosyltransferase activity produces 5-fluorouracil resistance in a human gastric cancer cell line. Oncology reports, 2008, Volume: 20, Issue:6 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Orotate Phosphoribosyltransferase; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stomach Neoplasms; Taxoids; Tetrazolium Salts; Thiazoles	2008
Antitumor efficiency of the cytosine deaminase/5-fluorocytosine suicide gene therapy system on malignant gliomas: an in vivo study. Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:1 Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine Deaminase; DNA Primers; Escherichia coli; Flucytosine; Fluorescent Antibody Technique; Fluorouracil; Genetic Therapy; Glioma; Immunoblotting; Mice; Mice, Nude; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles	2009
Porphyrins containing nitric oxide donors: Synthesis and cancer cell-oriented NO release. Bioorganic & medicinal chemistry letters, 2009, Mar-15, Volume: 19, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Porphyrins; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles	2009
Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells. Acta pharmacologica Sinica, 2009, Volume: 30, Issue:10 Topics: Adenomatous Polyposis Coli Protein; Antineoplastic Agents; beta Catenin; Cadherins; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Line, Tumor; Coloring Agents; Culture Media, Serum-Free; Cyclin D1; Fluorescent Antibody Technique, Direct; Fluorouracil; Heat-Shock Proteins; Humans; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation	2009
Synthesis and antiproliferative activities against Hep-G2 of salicylanide derivatives: potent inhibitors of the epidermal growth factor receptor (EGFR) tyrosine kinase. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:1 Topics: Aniline Compounds; Antineoplastic Agents; ErbB Receptors; Fluorouracil; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Binding; Salicylanilides; Salicylates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles	2011
Tyrosine phosphatase inhibitor-3 sensitizes melanoma and colon cancer to biotherapeutics and chemotherapeutics. Molecular cancer therapeutics, 2010, Volume: 9, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Fluorouracil; Humans; Interferon alpha-2; Interferon-alpha; Melanoma; Mice; Recombinant Proteins; Substrate Specificity; Thiazoles; Xenograft Model Antitumor Assays	2010
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma. Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:12 Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine	2010
Design and synthesis of novel camptothecin/5-fluorouracil conjugates as cytotoxic agents. Natural product research, 2011, Volume: 25, Issue:19 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cytotoxins; Drug Synergism; Fluorouracil; Humans; Inhibitory Concentration 50; Lactones; Mice; Molecular Structure; Tetrazolium Salts; Thiazoles	2011
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1. Cancer research, 2011, Aug-01, Volume: 71, Issue:15 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; CDC2 Protein Kinase; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inhibitor of Apoptosis Proteins; Irinotecan; Mice; Mice, Nude; Neoplasm Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-myb; Pyrimidines; Recombinant Proteins; RNA, Small Interfering; Thiazoles; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2011
Natural resistance to apoptosis correlates with resistance to chemotherapy in colorectal cancer cells. Clinical and experimental medicine, 2012, Volume: 12, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Colorimetry; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Organoplatinum Compounds; Oxaliplatin; Staining and Labeling; Tetrazolium Salts; Thiazoles	2012
Effect of radiotherapy and chemotherapy on the risk of mucositis during intensity-modulated radiation therapy for oropharyngeal cancer. International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Cisplatin; Confidence Intervals; Dasatinib; Docetaxel; Female; Fluorouracil; Humans; Induction Chemotherapy; Male; Middle Aged; Mouth Mucosa; Odds Ratio; Organs at Risk; Oropharyngeal Neoplasms; Pyrimidines; Radiography; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Stomatitis; Taxoids; Thiazoles; Tumor Burden	2012
Both hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity. PloS one, 2011, Volume: 6, Issue:12 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Baculoviridae; Cell Line, Tumor; Colonic Neoplasms; Cross-Linking Reagents; DNA Mismatch Repair; DNA-Binding Proteins; Fluorouracil; Humans; Microsatellite Repeats; Oligonucleotides; Recombinant Proteins; Surface Plasmon Resonance; Tetrazolium Salts; Thiazoles; Treatment Outcome	2011
MiR-122 increases sensitivity of drug-resistant BEL-7402/5-FU cells to 5-fluorouracil via down-regulation of bcl-2 family proteins. Die Pharmazie, 2011, Volume: 66, Issue:12 Topics: Antimetabolites; bcl-X Protein; Blotting, Western; Cell Death; Cell Line, Tumor; Coloring Agents; Down-Regulation; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Genetic Vectors; Humans; Microarray Analysis; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transfection; Tumor Suppressor Protein p53	2011
PCL films incorporated with paclitaxel/5-fluorouracil: Effects of formulation and spacial architecture on drug release. International journal of pharmaceutics, 2012, May-10, Volume: 427, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coloring Agents; Delayed-Action Preparations; Diffusion; Drug-Eluting Stents; Female; Fluorouracil; Mice; Microscopy, Electron, Scanning; Paclitaxel; Polyesters; Polyethylene Glycols; Solubility; Spectrophotometry, Ultraviolet; Surface Properties; Tetrazolium Salts; Thiazoles; X-Ray Diffraction	2012
Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma. Journal of liposome research, 2012, Volume: 22, Issue:3 Topics: Acetone; Amines; Antineoplastic Agents; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Delayed-Action Preparations; Disaccharides; Drug Carriers; Drug Delivery Systems; Flow Cytometry; Fluorouracil; Galactose; Glycerides; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Nanoparticles; Oleic Acid; Particle Size; Polysorbates; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tetrazolium Salts; Thiazoles; Toxicity Tests	2012
The effects of 5-fluorouracil alone and in combination with 13-cis retinoic acid and vitamin D3 on human oral squamous cell carcinoma lines. The journal of contemporary dental practice, 2012, May-01, Volume: 13, Issue:3 Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Combinations; Drug Synergism; Fluorouracil; Humans; In Situ Nick-End Labeling; Isotretinoin; Mouth Neoplasms; Tetrazolium Salts; Thiazoles	2012
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen. PloS one, 2012, Volume: 7, Issue:10 Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil	2012
Knockdown of MMP-7 inhibits cell proliferation and enhances sensitivity to 5-Fluorouracil and X-ray irradiation in colon cancer cells. Clinical and experimental medicine, 2014, Volume: 14, Issue:1 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Epithelial Cells; Flow Cytometry; Fluorouracil; Gene Knockdown Techniques; Humans; Matrix Metalloproteinase 7; Staining and Labeling; Tetrazolium Salts; Thiazoles; X-Rays	2014
Identification of CD44+ cancer stem cells in human gastric cancer. Hepato-gastroenterology, 2013, Volume: 60, Issue:124 Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Flow Cytometry; Fluorouracil; Humans; Hyaluronan Receptors; Mice; Mice, SCID; Neoplastic Stem Cells; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles	2013
Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis. Drug and chemical toxicology, 2014, Volume: 37, Issue:1 Topics: Analysis of Variance; Animals; Apoptosis; Cell Transformation, Neoplastic; DNA Primers; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Flow Cytometry; Fluorouracil; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Tumor Cells, Cultured	2014
Knockdown of PLA2G2A sensitizes gastric cancer cells to 5-FU in vitro. European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:13 Topics: Animals; Antimetabolites; Apoptosis; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Fluorouracil; Genetic Vectors; Group II Phospholipases A2; Humans; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection	2013
Cytotoxicity and enhancement activity of essential oil from Zanthoxylum bungeanum Maxim. as a natural transdermal penetration enhancer. Journal of Zhejiang University. Science. B, 2014, Volume: 15, Issue:2 Topics: Administration, Cutaneous; Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Fluorouracil; Humans; Indomethacin; Inhibitory Concentration 50; Keratinocytes; Male; Oils, Volatile; Plant Oils; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Zanthoxylum	2014
In vitro chemosensitivity assay of ascites in epithelial ovarian cancer. European journal of gynaecological oncology, 2013, Volume: 34, Issue:6 Topics: Antineoplastic Agents; Ascites; Carboplatin; Carcinoma, Ovarian Epithelial; Coloring Agents; Deoxycytidine; Disease Progression; Drug Screening Assays, Antitumor; Epirubicin; Etoposide; Female; Fluorouracil; Gemcitabine; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Predictive Value of Tests; Retrospective Studies; Survival Rate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2013
Let-7 g microRNA sensitizes fluorouracil-resistant human hepatoma cells. Die Pharmazie, 2014, Volume: 69, Issue:4 Topics: Antimetabolites, Antineoplastic; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Coloring Agents; Cyclin A; Down-Regulation; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Genetic Vectors; HMGA2 Protein; Humans; Liver Neoplasms; MicroRNAs; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection	2014
The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells. Journal of cellular and molecular medicine, 2015, Volume: 19, Issue:7 Topics: Aged; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogenesis; Cell Line, Tumor; Chemotherapy, Adjuvant; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Recurrence, Local; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; Signal Transduction; Thiazoles	2015
The protective effect of pyrimidine nucleosides on human HaCaT keratinocytes treated with 5-FU. Anticancer research, 2015, Volume: 35, Issue:3 Topics: Antimetabolites, Antineoplastic; Cells, Cultured; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Humans; Keratinocytes; Pyrimidine Nucleosides; Tetrazolium Salts; Thiazoles; Thymidylate Synthase	2015
Genotoxic potential of selected cytostatic drugs in human and zebrafish cells. Environmental science and pollution research international, 2016, Volume: 23, Issue:15 Topics: Acridine Orange; Animals; Cell Line; Cell Survival; Cisplatin; Cytostatic Agents; Ethidium; Etoposide; Fluorouracil; Hep G2 Cells; Humans; Lymphocytes; Tetrazolium Salts; Thiazoles; Zebrafish	2016
The hypoxia-mimetic agent CoCl₂ induces chemotherapy resistance in LOVO colorectal cancer cells. Molecular medicine reports, 2016, Volume: 13, Issue:3 Topics: bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cobalt; Colorectal Neoplasms; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Real-Time Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles	2016
NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell. Scientific reports, 2016, 04-25, Volume: 6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Self Renewal; Cisplatin; Diamines; Docetaxel; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Lymphatic Metastasis; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Receptor, Notch1; RNA, Small Interfering; Taxoids; Thiazoles; Xenograft Model Antitumor Assays	2016
Inhibitory effects of bevacizumab monoclonal antibodies in combination with chemotherapy in different time sequences on a human gastric carcinoma cell line. Irish journal of medical science, 2017, Volume: 186, Issue:2 Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bevacizumab; Cell Cycle; Cell Line, Tumor; Fluorouracil; Humans; Stomach Neoplasms; Tetrazolium Salts; Thiazoles	2017
Label-free fluorescence turn-on detection of uracil DNA glycosylase activity based on G-quadruplex formation. Talanta, 2016, Nov-01, Volume: 160 Topics: Benzothiazoles; Fluorescence; Fluorescent Dyes; Fluorouracil; G-Quadruplexes; HeLa Cells; Humans; Thiazoles; Uracil-DNA Glycosidase	2016
Dioscin suppresses hepatocellular carcinoma tumor growth by inducing apoptosis and regulation of TP53, BAX, BCL2 and cleaved CASP3. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Nov-15, Volume: 23, Issue:12 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Diosgenin; DNA Fragmentation; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Tumor Suppressor Protein p53	2016
Dual sphingosine kinase inhibitor SKI-II enhances sensitivity to 5-fluorouracil in hepatocellular carcinoma cells via suppression of osteopontin and FAK/IGF-1R signalling. Biochemical and biophysical research communications, 2017, 06-10, Volume: 487, Issue:4 Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Fluorouracil; Focal Adhesion Kinase 1; Hep G2 Cells; Humans; Liver Neoplasms; Osteopontin; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Structure-Activity Relationship; Thiazoles	2017
Secretion metabolites of probiotic yeast, Pichia kudriavzevii AS-12, induces apoptosis pathways in human colorectal cancer cell lines. Nutrition research (New York, N.Y.), 2017, Volume: 41 Topics: Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Caco-2 Cells; Caspase 3; Caspase 8; Caspase 9; Cell Proliferation; Colorectal Neoplasms; Fluorouracil; HT29 Cells; Humans; Indoles; Pichia; Probiotics; Tetrazoles; Tetrazolium Salts; Thiazoles	2017
[A Case Report of Luminal A Male Inflammatory Breast Cancer that Was Difficult to Treat Because of Trousseau Syndrome]. Journal of UOEH, 2019, Volume: 41, Issue:2 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms, Male; Cilostazol; Combined Modality Therapy; Cyclophosphamide; Docetaxel; Drug Combinations; Epirubicin; Factor Xa Inhibitors; Fatal Outcome; Fluorouracil; Humans; Inflammatory Breast Neoplasms; Male; Oxonic Acid; Pyridines; Radiotherapy, Intensity-Modulated; Skin Neoplasms; Syndrome; Tegafur; Thiazoles; Thrombophilia	2019
[Successful Management of Deep Vein Thromboembolism and Pulmonary Embolism by Edoxaban for Long-Term 5-FU-Based Chemotherapy for Colon Cancer-A Case Report]. Gan to kagaku ryoho. Cancer & chemotherapy, 2019, Volume: 46, Issue:12 Topics: Aged; Anticoagulants; Colonic Neoplasms; Fluorouracil; Humans; Pulmonary Embolism; Pyridines; Thiazoles; Thromboembolism; Venous Thromboembolism	2019
Synthetic antiprotozoal thiazolide drug induced apoptosis in colorectal cancer cells: implications of IL-6/JAK2/STAT3 and p53/caspases-dependent signaling pathways based on molecular docking and in vitro study. Molecular and cellular biochemistry, 2020, Volume: 469, Issue:1-2 Topics: Antineoplastic Agents; Antiprotozoal Agents; Apoptosis; Caspases; Cell Cycle; Cell Survival; Colorectal Neoplasms; Cytochromes c; Fluorouracil; HCT116 Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Interleukin-6; Janus Kinase 2; Molecular Docking Simulation; Nitro Compounds; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; STAT3 Transcription Factor; Thiazoles; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A	2020
Discovery of new fluorescent thiazole-pyrazoline derivatives as autophagy inducers by inhibiting mTOR activity in A549 human lung cancer cells. Cell death & disease, 2020, 07-20, Volume: 11, Issue:7 Topics: A549 Cells; Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chick Embryo; Fluorescence; Fluorouracil; Humans; Inhibitory Concentration 50; Lung Neoplasms; Lysosomes; Pyrazoles; Structure-Activity Relationship; Tacrolimus Binding Protein 1A; Thiazoles; TOR Serine-Threonine Kinases	2020
Gelatin/carboxymethyl cellulose based stimuli-responsive hydrogels for controlled delivery of 5-fluorouracil, development, in vitro characterization, in vivo safety and bioavailability evaluation. Carbohydrate polymers, 2021, Apr-01, Volume: 257 Topics: Animals; Biological Availability; Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Cattle; Chlorocebus aethiops; Cross-Linking Reagents; Drug Delivery Systems; Drug Liberation; Fluorouracil; Gelatin; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; In Vitro Techniques; Microscopy, Electron, Scanning; Nanoparticles; Polymerization; Polymers; Porosity; Rabbits; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles; Vero Cells; X-Ray Diffraction	2021
A selective p53 activator and anticancer agent to improve colorectal cancer therapy. Cell reports, 2021, 04-13, Volume: 35, Issue:2 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colorectal Neoplasms; Doxorubicin; Drug Discovery; Drug Synergism; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; Mice, Nude; Protein Binding; Pyrroles; Thiazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2021
Synergistic Interaction of CPP2 Coupled with Thiazole Derivates Combined with Clotrimazole and Antineoplastic Drugs in Prostate and Colon Cancer Cell Lines. International journal of molecular sciences, 2021, Nov-05, Volume: 22, Issue:21 Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell-Penetrating Peptides; Clotrimazole; Colonic Neoplasms; Drug Synergism; Fluorouracil; Humans; Male; Paclitaxel; Prostatic Neoplasms; Thiazoles	2021
Novel Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:3 Topics: Amides; Antineoplastic Agents; Fluorouracil; Humans; Neoplasms; Thiadiazoles; Thiazoles	2023
Rational synthesis, anticancer activity, and molecular docking studies of novel benzofuran liked thiazole hybrids. Molecular diversity, 2023, Volume: 27, Issue:3 Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thiazoles	2023