thiazoles has been researched along with fatostatin in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 23 (76.67) | 24.3611 |
| 2020's | 6 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abu-Elheiga, L; Asakura, K; Choo, HY; Gu, Z; Kamisuki, S; Kawazoe, Y; Kugimiya, A; Kwon, Y; Mao, Q; Sakai, J; Sato, S; Shinohara, T; Uesugi, M; Wakil, SJ | 1 |
| Abu-Elheiga, L; Choo, HY; Kamisuki, S; Kugimiya, A; Shimogawa, H; Shirakawa, T; Uesugi, M; Wakil, SJ; Yamada, K | 1 |
| Uesugi, M | 1 |
| Chen, YT; Hu, P; Huang, WC; Li, X | 1 |
| Agarwal, C; Agarwal, R; Deep, G; Nambiar, DK; Singh, RP | 1 |
| Chen, X; Dickhout, JG; Gao, B; Krepinsky, JC; Li, R; Lu, C; Mohammed-Ali, Z; Wang, TN; Yum, V | 1 |
| Bai, JL; Chen, SE; Chen, Y; Feng, RF; Guo, PH; Huo, SD; Lu, JX; Ma, ZR; Qiao, ZL; Zhang, GH | 1 |
| Dossena, S; Nofziger, C; Patsch, W; Paulmichl, M; Soyal, SM | 1 |
| Gulappa, T; Menon, B; Menon, KM | 1 |
| Chung, LW; Huang, WC; Li, X; Wu, JB | 1 |
| Espenshade, PJ; Machamer, CE; Shao, W | 1 |
| Ali, N; Argent, E; Brown, AJ; Chai, RC; Jurczyluk, J; Mehr, S; Munoz, MA; Palendira, U; Preston, A; Quinn, JM; Rogers, MJ; Skinner, OP; Tangye, SG; Ziegler, JB | 1 |
| Bensinger, SJ; Cheung, K; Gholkar, AA; Hamideh, SA; Khuu, C; Lo, YC; Nnebe, C; Torres, JZ; Williams, KJ | 1 |
| Chen, X; Gao, B; Krepinsky, JC; Mustafa, M; Wang, TN | 1 |
| Huang, G; Jia, W; Li, J; Liu, J; Liu, L; Miao, P; Song, S; Sun, X; Yan, H; Yang, H; Zhao, L; Zhao, X; Zhou, X | 1 |
| Gopalakrishnan, V; Sekar, S; Taghibiglou, C | 1 |
| Jiménez de Oya, N; Martín-Acebes, MA; Merino-Ramos, T; Saiz, JC | 1 |
| Bogan, RL; Hernández-Ledezma, JJ; Hutchison, SM; Xu, Y | 1 |
| Gao, B; Ingram, AJ; Krepinsky, JC; Marway, M; Mehta, N; Parthasarathy, P; Van Krieken, R | 1 |
| Gao, S; Jiang, J; Li, W; Li, X; Liu, Z; Shi, Z; Wang, Y | 1 |
| Akahori, D; Amano, Y; Goto, A; Hasegawa, H; Kakutani, T; Koda, K; Koyauchi, T; Matsui, T; Ozawa, Y; Sato, Y; Suda, T; Yokomura, K | 1 |
| Agostinis, P; Bosisio, F; Dehairs, J; Derua, R; Duarte, JAG; Fendt, SM; Marine, JC; Nittner, D; Nys, K; Pérez, MV; Rambow, F; Rogiers, A; Swinnen, JV; Talebi, A; Van den Eynde, K; Van den Oord, J; Vanderhoydonc, F; Waelkens, E | 1 |
| Dawson, CW; Kang, W; Ko, CW; Lo, AK; Lo, KW; Lung, RW; To, KF; Yeung, WW; Young, LS | 1 |
| Fong, IH; Hsu, TN; Huang, CM; Huang, CS; Huang, MS; Lee, WH; Liu, SC | 1 |
| Chen, S; Li, W; Yao, L | 1 |
| Chen, C; Gao, L; Li, C; Liang, X; Lin, Q; Ma, C; Song, X; Wang, T; Wang, Z; Wu, Z; Xu, L; Yu, X; Yue, X; Zhang, Y; Zhao, S | 1 |
| Chen, B; Chen, T; Duan, Y; Han, D; Li, C; Li, Y; Liang, Y; Liu, Y; Song, X; Wang, L; Wang, X; Yang, Q; Zhang, H; Zhang, N; Zhao, W | 1 |
| Guo, K; Jiang, J; Liu, Z; Lu, W; Ma, X; Qiu, C; Wei, L; Yan, H; Zhao, T | 1 |
| Akizuki, S; Hashimoto, M; Kitagori, K; Ma, S; Mimori, T; Morinobu, A; Murakami, K; Nakashima, R; Ohmura, K; Tanaka, K; Tanaka, M; Yoshifuji, H | 1 |
| Fan, X; Jiang, Z; Li, M; Lu, Q; Yu, Q; Zhang, L; Zhao, W; Zhu, Y | 1 |
2 review(s) available for thiazoles and fatostatin
| Article | Year |
|---|---|
[Control and analysis of cells by synthetic small molecules].
Topics: Adamantane; Animals; Benzopyrans; Cell- and Tissue-Based Therapy; Combinatorial Chemistry Techniques; Humans; Indoles; Intercellular Signaling Peptides and Proteins; Molecular Biology; Molecular Conformation; Molecular Weight; Piperazines; Pyridines; Signal Transduction; Sulfonamides; Thiazoles; Transcription, Genetic | 2012 |
Targeting SREBPs for treatment of the metabolic syndrome.
Topics: Animals; Humans; Metabolic Syndrome; Protein Kinase Inhibitors; Pyridines; Sterol Regulatory Element Binding Proteins; Thiazoles; Triterpenes | 2015 |
28 other study(ies) available for thiazoles and fatostatin
| Article | Year |
|---|---|
A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.
Topics: Animals; Blood Glucose; Body Weight; CHO Cells; Cricetinae; Cricetulus; Fatty Acids; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Obese; Protein Binding; Protein Structure, Tertiary; Pyridines; Sterol Regulatory Element Binding Proteins; Thiazoles; Transcription, Genetic | 2009 |
Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.
Topics: Animals; Blood Glucose; CHO Cells; Cricetinae; Cricetulus; Eating; Hepatocytes; Male; Membranes, Artificial; Mice; Mice, Obese; Permeability; Pyridines; Solubility; Sterol Regulatory Element Binding Proteins; Structure-Activity Relationship; Sulfonamides; Thiazoles | 2011 |
Fatostatin displays high antitumor activity in prostate cancer by blocking SREBP-regulated metabolic pathways and androgen receptor signaling.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cholesterol; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; NIH 3T3 Cells; Prostatic Neoplasms; Pyridines; Receptors, Androgen; Signal Transduction; Sterol Regulatory Element Binding Proteins; Thiazoles; Xenograft Model Antitumor Assays | 2014 |
Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Lipid Metabolism; Male; Metribolone; Molecular Targeted Therapy; Phosphorylation; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pyridines; Silybin; Silymarin; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Thiazoles; Transfection | 2014 |
SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis.
Topics: Angiotensin II; Animals; Cells, Cultured; Endoplasmic Reticulum Stress; ErbB Receptors; Fibronectins; Fibrosis; Intracellular Signaling Peptides and Proteins; Kidney; Male; Membrane Proteins; Mesangial Cells; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency, Chronic; Serine Proteases; Sp1 Transcription Factor; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transforming Growth Factor beta1; Up-Regulation | 2015 |
ChREBP and LXRα mediate synergistically lipogenesis induced by glucose in porcine adipocytes.
Topics: Adipocytes; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Glucose; Hydrocarbons, Fluorinated; Lipogenesis; Liver X Receptors; Male; Orphan Nuclear Receptors; Pyridines; RNA, Small Interfering; Signal Transduction; Sulfonamides; Sus scrofa; Thiazoles | 2015 |
miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries.
Topics: Animals; Antagomirs; Chorionic Gonadotropin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation; MAP Kinase Signaling System; MicroRNAs; Oligonucleotides; Ovary; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Rats, Sprague-Dawley; Receptors, LH; Ribonucleoproteins; RNA-Binding Proteins; Sterol Regulatory Element Binding Proteins; Thiazoles | 2015 |
Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Nude; Mutation; Prostatic Neoplasms; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sterol Regulatory Element Binding Proteins; Taxoids; Thiazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2015 |
Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Endoplasmic Reticulum; Golgi Apparatus; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Protein Transport; Pyridines; Thiazoles | 2016 |
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.
Topics: Cell Line; Child; Child, Preschool; Female; Humans; Interleukin-1beta; Isotope Labeling; Leukocytes, Mononuclear; Male; Mevalonate Kinase Deficiency; Protein Prenylation; Pyridines; rab GTP-Binding Proteins; Sterol Regulatory Element Binding Protein 1; Temperature; Thiazoles | 2016 |
Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division.
Topics: Cell Division; G2 Phase; HeLa Cells; Humans; Neoplasm Proteins; Neoplasms; Pyridines; Spindle Apparatus; Sterol Regulatory Element Binding Proteins; Thiazoles | 2016 |
SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction.
Topics: Animals; Apoptosis; Fibrosis; Kidney; Male; Mice; Pyridines; Signal Transduction; Sterol Regulatory Element Binding Proteins; Thiazoles; Transforming Growth Factor beta; Up-Regulation; Ureteral Obstruction | 2016 |
Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Humans; Hydroxycholesterols; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Microtubule-Associated Proteins; Protein Kinase Inhibitors; Pyridines; Quinazolines; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Thiazoles; Triterpenes; Xenograft Model Antitumor Assays | 2016 |
Sterol regulatory element-binding protein 1 inhibitors decrease pancreatic cancer cell viability and proliferation.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Pancreatic Neoplasms; Pyridines; Pyrrolidines; Sterol Regulatory Element Binding Protein 1; Structure-Activity Relationship; Thiazoles | 2017 |
Antiviral Activity of Nordihydroguaiaretic Acid and Its Derivative Tetra-
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; HeLa Cells; Humans; Lipid Metabolism; Masoprocol; Pyridines; Pyrrolidines; Sterol Regulatory Element Binding Proteins; Thiazoles; Vero Cells; Virus Replication; West Nile Fever; West Nile virus; Zika Virus; Zika Virus Infection | 2017 |
The liver X receptors and sterol regulatory element binding proteins alter progesterone secretion and are regulated by human chorionic gonadotropin in human luteinized granulosa cells.
Topics: Animals; Cholesterol; Chorionic Gonadotropin; Female; Gene Expression Regulation; Humans; Hydrocarbons, Fluorinated; Liver X Receptors; Luteal Cells; Models, Biological; Phosphoproteins; Progesterone; Protein Kinase Inhibitors; Pyridines; Receptors, LDL; Sheep; Sterol Regulatory Element Binding Proteins; Sulfonamides; Thiazoles; Transcription, Genetic | 2018 |
Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Kidney; Male; Mice; Pyridines; Receptors, CCR2; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Thiazoles | 2018 |
Fatostatin suppresses growth and enhances apoptosis by blocking SREBP-regulated metabolic pathways in endometrial carcinoma.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Metabolic Networks and Pathways; Pyridines; Stem Cells; Sterol Regulatory Element Binding Proteins; Thiazoles | 2018 |
Clinical impact of minocycline on afatinib-related rash in patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carcinoma, Non-Small-Cell Lung; Diarrhea; Epidermal Growth Factor; Exanthema; Female; Humans; Lung Neoplasms; Male; Middle Aged; Minocycline; Mutation; Paronychia; Pyridines; Severity of Illness Index; Thiazoles | 2018 |
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Lipogenesis; Male; Melanocytes; Melanoma; Mice; Mice, Nude; Mice, SCID; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridines; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Thiazoles; Vemurafenib; Xenograft Model Antitumor Assays | 2018 |
Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Progression; Fatty Acid Synthase, Type I; Female; Herpesvirus 4, Human; Humans; Lipid Droplets; Lipogenesis; Luteolin; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Naphthyridines; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Pyridines; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Thiazoles; TOR Serine-Threonine Kinases; Viral Matrix Proteins; Xenograft Model Antitumor Assays | 2018 |
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Mice; MicroRNAs; Neoplastic Stem Cells; Pyridines; Sterol Regulatory Element Binding Protein 1; Survival Analysis; Thiazoles; Xenograft Model Antitumor Assays | 2019 |
Fatostatin inhibits the development of endometrial carcinoma in endometrial carcinoma cells and a xenograft model by targeting lipid metabolism.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Movement; Cell Survival; Cholesterol; Endometrial Neoplasms; Fatty Acids, Nonesterified; Female; Humans; Lipid Metabolism; Mice, Inbred BALB C; Pyridines; Thiazoles; Xenograft Model Antitumor Assays | 2020 |
ZHX2 inhibits SREBP1c-mediated de novo lipogenesis in hepatocellular carcinoma via miR-24-3p.
Topics: Adult; Aged; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Homeodomain Proteins; Humans; Lipogenesis; Liver Neoplasms; Male; Mice; Mice, Knockout; MicroRNAs; Middle Aged; Pyridines; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transcription Factors; Triglycerides | 2020 |
Fatostatin in Combination with Tamoxifen Induces Synergistic Inhibition in ER-Positive Breast Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Pyridines; Receptors, Estrogen; Structure-Activity Relationship; Tamoxifen; Thiazoles | 2020 |
Fatostatin reverses progesterone resistance by inhibiting the SREBP1-NF-κB pathway in endometrial carcinoma.
Topics: Endometrial Neoplasms; Endometrium; Female; Humans; NF-kappa B; Pyridines; Regulatory Elements, Transcriptional; Sterol Regulatory Element Binding Protein 1; Thiazoles; Transfection; Uterine Diseases | 2021 |
Fatostatin ameliorates inflammation without affecting cell viability.
Topics: Animals; Cell Survival; Inflammation; Mice; Pyridines; Thiazoles | 2022 |
Fatostatin inhibits SREBP2-mediated cholesterol uptake via LDLR against selective estrogen receptor α modulator-induced hepatic lipid accumulation.
Topics: Breast Neoplasms; Cholesterol; Estrogen Receptor alpha; Female; Humans; Liver; Non-alcoholic Fatty Liver Disease; Pyridines; Receptors, LDL; Selective Estrogen Receptor Modulators; Sterol Regulatory Element Binding Protein 2; Tamoxifen; Thiazoles | 2022 |