Compounds > thiazoles
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thiazoles and fanft

thiazoles has been researched along with fanft in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199081 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hyatt, CL; Javadpour, N; Soares, T1
Arai, M; Brigham, SC; Jacobs, JB; Plotkin, GM; Wolf, G1
Adolphs, HD; Kiel, H; Steffens, L; Thiele, J2
Arai, M; Cohen, SM; Friedell, GH; Jacobs, JB3
Arai, M; Cohen, SM; Friedell, GH; Johansson, S; Yang, JP1
Cohen, SM; Friedell, GH1
Alroy, J; Cohen, SM; Pauli, BU; Weinstein, RS1
Hyatt, C; Marrone, JC; Martino, C; Soloway, MS1
Alroy, J; Friedell, GH; Jacobs, JB; Merk, FB; Pauli, BU; Weinstein, RS1
Matsushima, M1
Murphy, GP; Williams, PD1
Soloway, MS1
Schlegel, JU1
Bryan, GT; Hayashida, S; Pamukcu, AM; Wang, CY1
Bryan, GT; Cohen, SM; Wittenberg, JF1
Cohen, SM; Hasegawa, R; Johansson, SL; Sakata, T1
Cohen, SM; Hasegawa, R1
Cohen, SM; Smith, RA; Tibbels, TS1
Davis, BB; Rice, JR; Spry, LA; Zenser, TV1
Anderström, C; Johansson, SL; Larsson, P1
Anderström, C; Johansson, SL1
Davis, BB; Lakshmi, VM; Mattammal, MB; White, E; Zenser, TV1
Heckl, W; Jocham, K; Täuber, J; Vohr, HW1
Bryan, GT; Ichikawa, M; Swaminathan, S1
Cano, M; Cohen, SM; Ellwein, LB; Hasegawa, R; St John, M1
Berger, MR; Habs, M; Petru, E; Schmähl, D1
Cohen, SM; Hasegawa, R; Johansson, SL; Sakata, T; Zenser, TV1
Davis, B; Lakshmi, VM; Spry, L; Zenser, T1
Cohen, SM; Davis, BB; Hasegawa, R; Johansson, SL; Sakata, T; Zenser, TV1
Imaida, K; Wang, CY1
Croft, WA; Hayashida, S; Kamiryo, Y; Wang, CY1
Bryan, GT; Erturk, E; Fujioka, H; Hibino, S; Ichikawa, M; Swaminathan, S1
Davis, BB; Rice, JR; Zenser, TV1
Hosaka, Y; Matsushima, T; Muramatsu, M; Nagase, S; Niijima, T1
Cohen, SM; Davis, BB; Spry, LA; Zenser, TV1
Morton, KC; Wang, CY1
Babayan, RK; Carpinito, GA; Cohen, EB; Ho, ZS; Krane, RJ; Osband, ME1
Croft, WA; Kamiryo, Y; Wang, CY1
Davis, BB; Wise, RW; Zenser, TV2
Hayashida, S; Wang, CY2
Bolla, RI; Davis, BB; Mattammal, MB; Palmier, MO; Zenser, TV1
Bryan, GT; Johnson, MD; Reznikoff, CA; Swaminathan, S1
Crabtree, WN; Matheny, RB; Murphy, WM; Soloway, MS1
Cohen, SM; Davis, BB; Murasaki, G; Zenser, TV1
Drago, JR1
Cohen, SM; Fukushima, S; Hasegawa, R; Murasaki, G; St John, M1
Bryan, GT; Croft, WA; Wang, CY1
Bryan, GT; Swaminathan, S2
Bryan, GT; Lower, GM; Swaminathan, S2
Davis, BB; Mattammal, MB; Zenser, TV5
Cohen, SM; Davis, BB; Fukushima, S; Mattammal, MB; Murasaki, G; Rapp, NS; Zenser, TV1
Cohen, SM; Murasaki, G1
Cohen, SM; Pauli, BU; Weinstein, RS1
Arai, M; Cohen, SM; Friedell, GH; Fukushima, S; St John, M1
Cohen, SM1
Garner, CD; Hirose, M; Wang, CY1
Croft, MA; Croft, WA; Lower, GM; Paulus, KP; Wang, CY; Williams, JH2
Bryan, GT; Ertürk, E; Swaminathan, S1
Cohen, SM; Fukushima, S; Greenfield, RE; Murasaki, G1
Mickey, DD; Mickey, GH; Murphy, WM; Niell, HB; Soloway, MS1
Allhoff, EP; Chapman, CM; Hagen, IK; Lin, CW; Lin, JC; Mei, H; Proppe, KH; Prout, GR1
Mickey, DD; Niell, HB; Soloway, MS; Wood, CA1
Bryan, GT; Ertürk, E; Headley, DB; Klopp, RG; Michie, PM1
Grossman, HB; Lesser, ML; Sonda, LP1
Cohen, SM; Friedell, GH; Fukushima, S; Jacobs, JB1
McCallum, LW; Nissenkorn, I; Soloway, MS1
Crooke, ST; Daskal, Y; DeFuria, MD; Soloway, MS1
Balin, VV; Pliss, GB; Vlasov, NN1
Bryan, GT; Matsushima, M1

Other Studies

81 other study(ies) available for thiazoles and fanft

ArticleYear
Immunologic features of a carcinogen-induced murine bladder cancer: in vivo and in vitro studies.
    Journal of surgical oncology, 1979, Volume: 11, Issue:2

    Topics: Animals; Antigens, Neoplasm; Cross Reactions; Cytotoxicity, Immunologic; Epitopes; FANFT; Female; Fetus; Immunity; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Pregnancy; Thiazoles; Urinary Bladder Neoplasms

1979
Uridine 5'-diphosphate galactose: glycoprotein galactosyl transferase activity in exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide.
    Cancer biochemistry biophysics, 1977, Volume: 2, Issue:2

    Topics: Animals; beta-N-Acetylglucosaminylglycopeptide beta-1,4-Galactosyltransferase; Epithelial Cells; Epithelium; FANFT; Female; Galactosyltransferases; Humans; Hyperplasia; Male; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms; Urine

1977
Biological behavior of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide induced carcinoma of the transitional epithelium in the rat.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1978, Volume: 91, Issue:3

    Topics: Animals; Carcinoma, Transitional Cell; FANFT; Female; Kidney Neoplasms; Kidney Pelvis; Neoplasm Staging; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder Neoplasms

1978
Effect of dose on urinary bladder carcinogenesis induced in F344 rats by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Microvilli; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms

1979
The influence of N-[4-(5-nitro-2-Furyl)-2-thiazolyl]formamide and phenacetin on the immune status in male Fischer rats.
    Investigative urology, 1978, Volume: 15, Issue:4

    Topics: Animals; Azathioprine; FANFT; Hemolytic Plaque Technique; Immunity; Immunity, Cellular; Lectins; Lymphocyte Activation; Male; Phenacetin; Rats; Rats, Inbred Strains; Thiazoles

1978
Carcinoma of the urinary bladder.
    The American journal of pathology, 1979, Volume: 95, Issue:3

    Topics: Animals; Carcinoma, Transitional Cell; Disease Models, Animal; FANFT; Humans; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms

1979
Induction of transitional cell carcinoma of the urinary bladder in rats by feeding N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide. Histological and ultrastructural findings.
    Urological research, 1978, Volume: 6, Issue:1

    Topics: Animals; Carcinoma, Transitional Cell; Disease Models, Animal; Epithelium; FANFT; Female; Neoplasms, Experimental; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1978
Desmosome ultrastructure and biological behavior of chemical carcinogen-induced urinary bladder carcinomas.
    Cancer research, 1978, Volume: 38, Issue:10

    Topics: Animals; Carcinoma, Transitional Cell; Cell Adhesion; Desmosomes; FANFT; Male; Microscopy, Electron; Neoplasm Invasiveness; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder Neoplasms

1978
Immunogenicity of N-[-4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced bladder cancer.
    National Cancer Institute monograph, 1978, Issue:49

    Topics: Animals; Antigens, Neoplasm; Carcinoma, Transitional Cell; Cross Reactions; FANFT; Female; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms

1978
A long-term study of reversible and progressive urinary bladder cancer lesions in rats fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Precancerous Conditions; Rats; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1977
Malignant transformation of urinary bladder in humans and in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-exposed Fischer rats: ultrastructure of the major components of the permeability barrier.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cell Transformation, Neoplastic; Epithelium; FANFT; Humans; Intercellular Junctions; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1977
[The role of L-tryptophan's promoting factor on tumorgenesis in the urinary bladder. 2. Urinary bladder carcinogenicity of FANFT (initiating factor) and L-tryptophan (promoting factor) in mice (author's transl)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1977, Volume: 68, Issue:8

    Topics: Animals; FANFT; Female; Mice; Neoplasms, Experimental; Thiazoles; Tryptophan; Urinary Bladder Neoplasms

1977
Experimental bladder tumor induction, propagation, and therapy.
    Urology, 1976, Volume: 8, Issue:1

    Topics: Administration, Oral; Animals; Carcinoma, Transitional Cell; FANFT; Female; Mice; Mice, Inbred C3H; Mitomycins; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thiazoles; Urinary Bladder Neoplasms

1976
FANFT-induced bladder tumors.
    Urology, 1976, Volume: 8, Issue:5

    Topics: Animals; Disease Models, Animal; FANFT; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms

1976
Light and scanning electron microscopy of exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:1

    Topics: Animals; Epithelial Cells; Epithelium; FANFT; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms; Urine

1976
Letter: Re: failure of ascorbic acid to inhibit FANFT-induced bladder cancer.
    The Journal of urology, 1976, Volume: 115, Issue:2

    Topics: Animals; Ascorbic Acid; Dogs; FANFT; Mice; Thiazoles; Urinary Bladder Neoplasms

1976
Enhancing effect of allopurinol on the induction of bladder cancer in rats by n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Cancer research, 1976, Volume: 36, Issue:5

    Topics: Allopurinol; Animals; Carcinoma, Transitional Cell; Cytosol; Drug Synergism; FANFT; Female; Liver; Neoplasms, Experimental; Nitrate Reductases; Rats; Sulfhydryl Compounds; Thiazoles; Time Factors; Tryptophan; Urinary Bladder Neoplasms

1976
Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide.
    Cancer research, 1976, Volume: 36, Issue:7 PT 1

    Topics: Animals; Body Weight; FANFT; Female; Metaplasia; Neoplasms, Experimental; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Vitamin A; Vitamin A Deficiency

1976
Effect of aspirin on urinary bladder carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Animals; Aspirin; FANFT; Kidney; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1989
Immunohistochemical study of keratin in proliferative bladder epithelium induced by freezing, cyclophosphamide or N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in the rat.
    Carcinogenesis, 1985, Volume: 6, Issue:3

    Topics: Animals; Cyclophosphamide; Epithelium; FANFT; Freezing; Histocytochemistry; Hyperplasia; Immunoenzyme Techniques; Keratins; Male; Rats; Rats, Inbred F344; Thiazoles; Ulcer; Urinary Bladder

1985
Quantitation of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and 2-amino-4-(5-nitro-2-furyl)thiazole in rodent diet.
    Journal of chromatography, 1989, Mar-31, Volume: 465, Issue:2

    Topics: Animal Feed; Animals; Chromatography, High Pressure Liquid; FANFT; Food Contamination; Nitrofurans; Rats; Spectrophotometry, Ultraviolet; Thiazoles

1989
Effect of peroxidase inhibitors on an in vivo metabolite of the urinary bladder carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
    Cancer research, 1988, Jan-15, Volume: 48, Issue:2

    Topics: Acetylcysteine; Animals; Carcinogens; FANFT; Glutathione; Male; Methimazole; Peroxidases; Propylthiouracil; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms

1988
The influence of urinary tract infection on the incidence of urinary tract tumors in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide induced carcinogenesis in male Sprague-Dawley rats.
    Cancer letters, 1987, Volume: 37, Issue:1

    Topics: Animals; Cocarcinogenesis; Disease Susceptibility; Escherichia coli Infections; FANFT; Hyperplasia; Inflammation; Kidney Pelvis; Male; Rats; Rats, Inbred Strains; Thiazoles; Urinary Tract Infections; Urologic Neoplasms

1987
The influence of antipyrene on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced urinary tract carcinogenesis.
    Carcinogenesis, 1988, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Cocarcinogenesis; FANFT; Kidney Neoplasms; Kidney Papillary Necrosis; Kidney Pelvis; Male; Rats; Rats, Inbred Strains; Thiazoles; Urinary Bladder Neoplasms

1988
'Revised' mass spectral identification of 2-amino-4-(5-nitro-2-furyl)thiazole metabolites.
    Biomedical & environmental mass spectrometry, 1988, May-01, Volume: 15, Issue:9

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; FANFT; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Male; Mass Spectrometry; Microsomes; Oxidation-Reduction; Sheep; Thiazoles

1988
Identification of inhibitory growth factors from a N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced murine bladder cancer cell line.
    Urologia internationalis, 1987, Volume: 42, Issue:4

    Topics: Animals; Carcinoma, Transitional Cell; Cell Line; Cell Transformation, Neoplastic; Chromatography, Gel; Chromatography, High Pressure Liquid; FANFT; Growth Substances; Mice; Peptides; Rats; Thiazoles; Transforming Growth Factors; Urinary Bladder Neoplasms

1987
Identification of 4-(5-amino-2-furyl)thiazole (AFT) as a reductive metabolite of the carcinogen 4-(5-nitro-2-furyl)thiazole (NFT).
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Chromatography, High Pressure Liquid; FANFT; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; NADP; Rats; Thiazoles

1986
Effect of dose on the induction of urothelial proliferation by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and its relationship to bladder carcinogenesis in the rat.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; FANFT; Male; Rats; Rats, Inbred F344; Thiazoles; Thymidine; Urinary Bladder; Urinary Bladder Neoplasms

1986
Influence of the application mode of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide on the localization of its carcinogenic expression in female NMRI-mice.
    Cancer letters, 1986, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Animals; Carcinoma, Squamous Cell; FANFT; Female; Mice; Mice, Inbred Strains; Papilloma; Stomach Neoplasms; Thiazoles; Urinary Bladder Neoplasms

1986
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Animals; Aspirin; Body Weight; Cocarcinogenesis; FANFT; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Saccharin; Thiazoles; Urinary Bladder Neoplasms

1986
Metabolism and excretion of nitrofurothiazole bladder carcinogens.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2

    Topics: Animals; FANFT; Glomerular Filtration Rate; Metabolic Clearance Rate; Protein Binding; Rats; Rats, Inbred Strains; Serum Albumin; Thiazoles; Tissue Distribution; Urinary Bladder Neoplasms

1986
The effect of long-term administration of aspirin and sodium saccharin on the rat kidney.
    Toxicology and applied pharmacology, 1986, Volume: 86, Issue:1

    Topics: Administration, Oral; Animals; Aspirin; Carcinogens; Drug Interactions; FANFT; Kidney Papillary Necrosis; Male; Rats; Rats, Inbred F344; Saccharin; Thiazoles

1986
Effect of sodium phenobarbital and sodium saccharin in AIN-76A diet on carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and N,N-dibutylnitrosamine in male F344 rats.
    Cancer research, 1986, Volume: 46, Issue:12 Pt 1

    Topics: Animals; Esophageal Neoplasms; FANFT; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Stomach Neoplasms; Thiazoles; Thyroid Neoplasms; Urinary Bladder Neoplasms

1986
Production of urinary tract tumors by co-administration of uracil and N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in F344 rats.
    Cancer letters, 1987, Volume: 34, Issue:3

    Topics: Animals; Body Weight; Carcinoma; Cocarcinogenesis; FANFT; Female; Hyperplasia; Kidney Pelvis; Rats; Rats, Inbred F344; Thiazoles; Uracil; Ureter; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1987
Isolation and characterization of a new 5-aminofurylthiazole from the catalytic reduction of 4-(5-nitro-2-furyl)thiazole.
    Chemical & pharmaceutical bulletin, 1985, Volume: 33, Issue:12

    Topics: Chemical Phenomena; Chemistry; FANFT; Oxidation-Reduction; Thiazoles

1985
Formation of thioether conjugates of the bladder carcinogen ANFT catalyzed by prostaglandin H synthase.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Chromatography, Liquid; Electrochemistry; Enzyme Activation; FANFT; In Vitro Techniques; Prostaglandin-Endoperoxide Synthases; Sulfides; Thiazoles; Urinary Bladder Neoplasms

1985
Low susceptibility of analbuminemic rats to induction of bladder cancer by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:7

    Topics: Animals; FANFT; Hyperlipidemias; Male; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Serum Albumin; Thiazoles; Urinary Bladder Neoplasms

1985
Role of renal metabolism and excretion in 5-nitrofuran-induced uroepithelial cancer in the rat.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:3

    Topics: Administration, Oral; Animals; Aspirin; Carcinoma; FANFT; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Metabolic Clearance Rate; Probenecid; Rats; Rats, Inbred Strains; Thiazoles; Urinary Bladder Neoplasms

1985
Enhanced macromolecular binding of N-[4-(5-nitro-2-furyl)-2-thiazolyl]- formamide in germfree versus conventional rats.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: Animals; Chromatography, DEAE-Cellulose; DNA; FANFT; Female; Germ-Free Life; Kidney; Liver; Rats; Ribonucleases; RNA; Thiazoles; Urinary Bladder

1983
The relationship of histamine H2 receptor-bearing suppressor cells with the growth and metastasis of FANFT-induced bladder cancer.
    Journal of surgical oncology, 1983, Volume: 24, Issue:1

    Topics: Animals; Carcinoma, Transitional Cell; Cell Movement; FANFT; Female; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Phenotype; Receptors, Histamine; Receptors, Histamine H2; Spleen; T-Lymphocytes, Regulatory; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1983
Carcinogenicity of 2-amino-4-(5-nitro-2-furyl) thiazole in rats by oral and subcutaneous administration.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: Animals; Body Weight; Carcinogens; Carcinoma, Squamous Cell; Diet; FANFT; Female; Histiocytoma, Benign Fibrous; Injections, Subcutaneous; Male; Neoplasms, Experimental; Rats; Skin Neoplasms; Stomach Neoplasms; Thiazoles; Urologic Neoplasms

1982
Prostaglandin H synthase metabolism of the urinary bladder carcinogens benzidine and ANFT.
    Carcinogenesis, 1983, Volume: 4, Issue:3

    Topics: Animals; Benzidines; Carcinogens; Electron Spin Resonance Spectroscopy; FANFT; Free Radicals; Horseradish Peroxidase; Male; Microsomes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Thiazoles; Urinary Bladder Neoplasms

1983
Mutagenicity of urine of various species fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or 2-amino-4-(5-nitro-2-furyl)thiazole.
    Mutation research, 1984, Volume: 135, Issue:3

    Topics: Animals; Biotransformation; Carcinogens; Cricetinae; FANFT; Female; Guinea Pigs; Mesocricetus; Mice; Mutagenicity Tests; Mutagens; Mutation; Nitrofurans; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity; Thiazoles; Urinary Bladder Neoplasms; Urine

1984
Peroxidase metabolism of the urinary bladder carcinogen 2-amino-4-(5-nitro-2-furyl)thiazole.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Anaerobiosis; Animals; Benzidines; Carcinogens; Cattle; DNA; FANFT; Horseradish Peroxidase; Lactoperoxidase; Peroxidases; Prostaglandin-Endoperoxide Synthases; Thiazoles; Urinary Bladder Neoplasms

1983
Comparative effects of prostaglandin H synthase-catalyzed binding of two 5-nitrofuran urinary bladder carcinogens.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:1

    Topics: Animals; Carcinogens; DNA; FANFT; In Vitro Techniques; Oxidation-Reduction; Prostaglandin Endoperoxides; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Protein Binding; Proteins; Thiazoles; Urinary Bladder Neoplasms

1983
Bioconversion and macromolecular binding of 2-amino-4-(5-nitro-2-furyl)thiazole by cultured rat urothelial cells.
    Cancer research, 1984, Volume: 44, Issue:12 Pt 1

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Epithelium; FANFT; Male; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder

1984
Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats.
    Cancer letters, 1984, Volume: 24, Issue:1

    Topics: Animals; Caffeine; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; FANFT; Female; Glucaric Acid; Glucuronidase; Nitroreductases; Oxidoreductases; Phenothiazines; Rats; Rats, Inbred F344; Sugar Acids; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1984
Metastatic characteristics of four FANFT-induced murine bladder tumors.
    Urology, 1983, Volume: 22, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; FANFT; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Thiazoles; Urinary Bladder Neoplasms

1983
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced bladder carcinogenesis and enhancement of forestomach carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:1

    Topics: Animals; Aspirin; FANFT; Male; Rats; Stomach Neoplasms; Thiazoles; Urinary Bladder Neoplasms

1984
The Noble rat bladder cancer model. FANFT-induced tumors.
    Cancer, 1984, Mar-01, Volume: 53, Issue:5

    Topics: Animals; Cell Nucleus; Cyclophosphamide; Cytoplasm; Disease Models, Animal; FANFT; Female; Rats; Rats, Inbred Strains; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1984
Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced epithelial proliferation in the urinary bladder and forestomach of the rat.
    Cancer letters, 1984, Volume: 21, Issue:3

    Topics: Animals; Aspirin; Carcinogens; Cell Division; Epithelium; FANFT; Male; Rats; Rats, Inbred F344; Stomach Neoplasms; Thiazoles; Urinary Bladder Neoplasms

1984
Tumor production in germ-free rats fed 5-nitrofurans.
    Cancer letters, 1984, Volume: 21, Issue:3

    Topics: Animals; Biotransformation; Carcinogens; FANFT; Female; Germ-Free Life; Intestines; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrofurans; Nitrofurantoin; Rats; Rats, Inbred Strains; Thiazoles

1984
Biotransformation of the bladder carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in mice.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Animals; Biotransformation; Carbon Radioisotopes; FANFT; Female; Kinetics; Mass Spectrometry; Mice; Spectrophotometry; Thiazoles; Tissue Distribution; Urinary Bladder Neoplasms

1984
Nitroreductase-mediated metabolic activation of 2-amino-4-(5-nitro-2-furyl)thiazole and binding to nucleic acids and proteins.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Biotransformation; Carcinogens; FANFT; Kinetics; Liver; Male; Microsomes, Liver; Nitroreductases; Oxidoreductases; Proteins; Rats; RNA, Transfer; Saccharomyces cerevisiae; Thiazoles

1982
Metabolism of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide by prostaglandin endoperoxide synthetase.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; FANFT; In Vitro Techniques; Indomethacin; Kidney Medulla; Male; Microsomes; Prostaglandin Endoperoxides; Prostaglandin-Endoperoxide Synthases; Rabbits; Seminal Vesicles; Thiazoles

1980
Mechanism of FANFT cooxidation by prostaglandin endoperoxide synthetase.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acids; Benzene Derivatives; FANFT; Heme; Hemeproteins; In Vitro Techniques; Male; Microsomes; Oxidation-Reduction; Oxygen; Peroxidases; Peroxides; Prostaglandin Endoperoxides; Prostaglandin-Endoperoxide Synthases; Rabbits; Sheep; Substrate Specificity; Thiazoles

1980
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Aspirin; Biotransformation; Cyclooxygenase Inhibitors; FANFT; Hyperplasia; Male; Neoplasms, Experimental; Prostaglandins E; Rabbits; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1981
Prostaglandin hydroperoxidase-mediated 2-amino-4-(5-nitro-2-furyl) [14C]thiazole metabolism and nucleic acid binding.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Animals; Carcinogens; Cell-Free System; DNA; FANFT; Male; Microsomes; Peroxidases; Peroxides; Prostaglandin Endoperoxides; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rabbits; RNA, Transfer; Seminal Vesicles; Sheep; Thiazoles; Urinary Bladder

1981
Anaerobic metabolism and nuclear binding of the carcinogen 2-amino-4-(5-nitro-2-furyl)thiazole (ANFT).
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Anaerobiosis; Animals; Binding Sites; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; DNA; FANFT; Kidney; Microsomes; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nucleic Acids; Oxidation-Reduction; Protein Binding; Rabbits; RNA, Transfer; Thiazoles

1982
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder.
    Carcinogenesis, 1983, Volume: 4, Issue:1

    Topics: Animals; Cocarcinogenesis; Diet; FANFT; Growth; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Diseases; Urinary Bladder Neoplasms

1983
Deacetylation of 4-(5-acetylamino-2-furyl)thiazole and formation of 1-(4-thiazolyl)-3-cyano-1-propanone by rat liver tissues.
    Biochemical pharmacology, 1983, Jan-01, Volume: 32, Issue:1

    Topics: Animals; Biotransformation; Chemical Phenomena; Chemistry; FANFT; Female; In Vitro Techniques; Kinetics; Liver; Rats; Rats, Inbred Strains; Subcellular Fractions; Thiazoles

1983
Cellular changes in rat urinary bladder carcinomas induced by FANFT: a quantitative electron microscopic analysis.
    The Journal of urology, 1983, Volume: 129, Issue:3

    Topics: Animals; Carcinogens; Cell Membrane; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Epithelium; FANFT; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1983
Long term dose response study of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced urinary bladder carcinogenesis.
    Cancer letters, 1983, Volume: 18, Issue:3

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; FANFT; Hyperplasia; Male; Neoplasms, Experimental; Papilloma; Prognosis; Rats; Rats, Inbred F344; Thiazoles; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1983
Promotion of urinary bladder carcinogenesis.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Carcinogens; FANFT; Mice; Neoplasms, Experimental; Organ Specificity; Thiazoles; Urinary Bladder Neoplasms; Urine

1983
Effect of phenobarbital on the carcinogenesis of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
    Cancer letters, 1983, Volume: 19, Issue:3

    Topics: Animals; Carcinogens; Drug Interactions; Drug Synergism; FANFT; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344; Thiazoles; Urinary Bladder Neoplasms

1983
13-cis-retinoic acid: effect on urinary bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in Fischer rats.
    Cancer letters, 1981, Volume: 12, Issue:4

    Topics: Animals; Butylated Hydroxytoluene; Carcinogens; FANFT; Female; Isomerism; Isotretinoin; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Tretinoin; Urinary Bladder Neoplasms

1981
Mutagenicity, carcinogenicity, distribution, and nitroreduction of 4-(5-nitro-2-furyl)thiazole in the rat.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Carcinogens; Chromatography, High Pressure Liquid; Diet; FANFT; Feces; Female; Gas Chromatography-Mass Spectrometry; Liver Neoplasms; Mammary Neoplasms, Experimental; Mutagens; Nitrofurans; Rats; Salmonella typhimurium; Stomach Neoplasms; Thiazoles; Tissue Distribution

1981
Effect of regenerative hyperplasia on the urinary bladder: carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Cancer research, 1982, Volume: 42, Issue:1

    Topics: Animals; Cell Division; Cocarcinogenesis; Cyclophosphamide; FANFT; Hyperplasia; Male; Rats; Rats, Inbred F344; Regeneration; Saccharin; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1982
In vitro characterization of four N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) induced mouse bladder tumors.
    The Journal of urology, 1982, Volume: 127, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Line; FANFT; Karyotyping; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Thiazoles; Urinary Bladder Neoplasms

1982
Rat bladder isograft model for focal carcinoma.
    The Journal of urology, 1982, Volume: 128, Issue:3

    Topics: Animals; Carcinoma, Transitional Cell; FANFT; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Thiazoles; Transplantation, Isogeneic; Urinary Bladder Neoplasms

1982
Time- and concentration-dependent inhibition of the clonogenic growth of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced murine bladder tumor cell lines by cis-diamminedichloroplatinum(II).
    Cancer research, 1982, Volume: 42, Issue:3

    Topics: Animals; Cell Line; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; FANFT; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1982
Reductive metabolism of the carcinogen 4-(5-nitro-2-furyl)thiazole to 1-(4-thiazolyl)-3-cyano-1-propanone by rat liver subcellular fractions.
    Biochemical pharmacology, 1980, Volume: 29, Issue:24

    Topics: Animals; Biotransformation; Carcinogens; Cytosol; FANFT; In Vitro Techniques; Liver; Male; Microsomes, Liver; Nitrofurans; Oxidation-Reduction; Rats; Spectrum Analysis; Thiazoles

1980
Temporal comparisons of immune status and target organ histology in mice fed carcinogenic 5-nitrofurans and their nornitro analogs.
    Cancer research, 1981, Volume: 41, Issue:4

    Topics: Animals; Antibody Formation; Carcinogens; Diet; FANFT; Female; Furans; Immunity, Cellular; Leukemia, Experimental; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrofurans; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1981
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats.
    Investigative urology, 1981, Volume: 18, Issue:8

    Topics: Animals; Body Weight; Carcinoma, Papillary; Carcinoma, Transitional Cell; FANFT; Female; Hyperplasia; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Size; Rats; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1981
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
    Cancer research, 1981, Volume: 41, Issue:8

    Topics: Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; FANFT; Male; Neoplasms, Experimental; Rats; Saccharin; Thiazoles; Tryptophan; Urinary Bladder Neoplasms

1981
Synthetic retinamides: effect on urinary bladder carcinogenesis by FANFT in Fischer rats.
    Carcinogenesis, 1981, Volume: 2, Issue:6

    Topics: Animals; Body Weight; FANFT; Female; Neoplasms, Experimental; Rats; Rats, Inbred F344; Thiazoles; Tretinoin; Urinary Bladder Neoplasms

1981
Comparison between a purified and standard diet on FANFT-induced murine bladder cancer.
    Urology, 1981, Volume: 18, Issue:5

    Topics: Animal Feed; Animals; Body Weight; Diet; FANFT; Female; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Organ Size; Thiazoles; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1981
Morphological effects of mitomycin C administered intravesically to normal mice and mice with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induce bladder neoplasms.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Epithelium; FANFT; Female; Mice; Microscopy, Electron; Mitomycins; Neoplasms, Experimental; Thiazoles; Urinary Bladder; Urinary Bladder Neoplasms

1980
[Epithelial bladder tumor induction in rats with N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide].
    Voprosy onkologii, 1980, Volume: 26, Issue:3

    Topics: Animals; Carcinoma, Transitional Cell; FANFT; Formamides; Male; Neoplasms, Experimental; Papilloma; Rats; Thiazoles; Time Factors; Urinary Bladder Neoplasms

1980
Early induction of mouse urinary bladder ornithine decarboxylase activity by rodent vesical carcinogens.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Carcinogens; Enzyme Induction; Epithelium; FANFT; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Thiazoles; Tretinoin; Urinary Bladder; Urinary Bladder Neoplasms

1980
Co-oxidative metabolism of 2-amino-4-(5-nitro-2-furyl)-thiazole by prostaglandin hydroperoxidase.
    The Journal of laboratory and clinical medicine, 1980, Volume: 96, Issue:3

    Topics: Animals; Arachidonic Acids; Chromatography, Thin Layer; FANFT; Indomethacin; Male; Peroxidases; Prostaglandin Endoperoxides; Rabbits; Thiazoles

1980