thiazoles has been researched along with everolimus in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| von Mehren, M | 1 |
| Bardet, V; Bouscary, D; Chapuis, N; Dreyfus, F; Green, AS; Ifrah, N; Lacombe, C; Mayeux, P; Park, S; Tamburini, J; Uzunov, M; Willems, L | 1 |
| Hussar, DA | 1 |
| Chen, LT; Cheng, AL; Gao, M; Hsu, CH; Jeng, HJ; Kuo, SH; Lin, CH; Lu, YS; Yeh, KH; Yeh, PY | 1 |
| Liu, J; Liu, Y; Ma, Y; Zhang, J; Zhang, S; Zhang, X; Zhu, Y | 1 |
| Balakrishnar, B; Clements, A; Gao, B; Gurney, H; Wong, M; Yeap, S | 1 |
| Ho, SL; Lavi, E; Singh, R; Souweidane, MM; Zhou, Z | 1 |
| Ito, TK; Kadariya, Y; Pei, J; Sementino, E; Tan, Y; Testa, JR | 1 |
| Guo, WH; Lu, J; Wang, XZ; Zhang, JX; Zheng, JF | 1 |
| Atlı, Ö; Burukoğlu, D; Ergun, B; Ilgın, S; Musmul, A; Sırmagül, B | 1 |
| Aboukameel, A; Azmi, AS; Baloglu, E; Bhutani, D; Carlson, R; Elloul, S; Kauffman, M; Mohammad, RM; Muqbil, I; Senapedis, W; Shacham, S; Zonder, J | 1 |
| Aristizabal Prada, ET; Auernhammer, CJ; Briest, F; Detjen, K; Exner, S; Fischer, C; Freitag, H; Grabowski, P; Grossman, A; Grötzinger, C; Lauseker, M; Möbs, M; Nölting, S; Rentsch, J; Schrader, J; Siegmund, B; Weissmann, V | 1 |
| Auriemma, RS; Cappabianca, P; Cavallo, LM; Colao, A; De Martino, MC; Di Cera, M; Frio, F; Grasso, LFS; Patalano, R; Pivonello, C; Pivonello, R; Solari, D; Vitulli, F | 1 |
| Aristizabal Prada, ET; Auernhammer, CJ; Bechmann, N; Beuschlein, F; Bornstein, SR; Eisenhofer, G; Fankhauser, M; Fassnacht, M; Favier, J; Gieldon, L; Goncalves, J; Grossman, AB; Klink, B; Knösel, T; Lauseker, M; Maurer, J; Nölting, S; Orth, M; Pacak, K; Rank, P; Reincke, M; Rubinstein, G; Spitzweg, C; Spöttl, G; William, D; Ziegler, CG | 1 |
| Ayabe, T; Fujii, T; Hiraike, H; Honjo, H; Kawata, Y; Kojima, M; Makii, C; Matsumoto, Y; Miyagawa, Y; Nagasaka, K; Oda, K; Oki, S; Osuga, Y; Sone, K; Taguchi, A; Takeuchi, M; Tanikawa, M; Wada-Hiraike, O | 1 |
| Ajipa, O; Andre, F; Beck, JT; Blumenstein, L; Curigliano, G; Donnet, V; Fazio, N; Hubner, RA; Jhaveri, K; Lahner, H; Li, Z; Martin, M; Maur, M; Tortora, G | 1 |
| Albert, R; Alcon, C; Gómez Tejeda Zañudo, J; Letai, A; Montero, J; Samitier, J; Scaltriti, M; Wagle, N | 1 |
2 review(s) available for thiazoles and everolimus
| Article | Year |
|---|---|
Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bevacizumab; Clinical Trials as Topic; Dasatinib; Drug Resistance, Neoplasm; Everolimus; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Niacinamide; Oligonucleotides; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sirolimus; Staurosporine; Sunitinib; Thiazoles | 2006 |
Evidence for therapeutic drug monitoring of targeted anticancer therapies.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Area Under Curve; Benzamides; Benzenesulfonates; Cetuximab; Dasatinib; Drug Monitoring; Everolimus; Evidence-Based Medicine; Half-Life; Humans; Imatinib Mesylate; Indoles; Injections, Intravenous; Molecular Targeted Therapy; Neoplasms; Niacinamide; Phenylurea Compounds; Piperazines; Pyridines; Pyrimidines; Pyrroles; Rituximab; Sirolimus; Sorafenib; Sunitinib; Thiazoles | 2012 |
1 trial(s) available for thiazoles and everolimus
| Article | Year |
|---|---|
Alpelisib in combination with everolimus ± exemestane in solid tumours: Phase Ib randomised, open-label, multicentre study.
Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Drug Interactions; Europe; Everolimus; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Thiazoles; Treatment Outcome; United States | 2021 |
14 other study(ies) available for thiazoles and everolimus
| Article | Year |
|---|---|
Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Topics: Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; Apoptosis; Cell Cycle Proteins; Cell Proliferation; Cells, Cultured; Drug Evaluation, Preclinical; Drug Resistance; Everolimus; Hematopoiesis; Humans; Hydrazones; Leukemia, Myeloid, Acute; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Neoplastic Stem Cells; Nitro Compounds; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Sirolimus; Thiazoles; TOR Serine-Threonine Kinases; Transcription Factors | 2009 |
New Drugs2010, PART 1.
Topics: Acetamides; Antibodies, Monoclonal; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Azepines; Benzazepines; Benzhydryl Compounds; Benzyl Alcohol; Benzylamines; Cyclams; Cyclopropanes; Drug Combinations; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Ethanolamines; Everolimus; Febuxostat; Fluorenes; Fluoroquinolones; Gout Suppressants; Heterocyclic Compounds; Humans; Immunosuppressive Agents; Indoles; Lacosamide; Milnacipran; Oligopeptides; Phenols; Selective Serotonin Reuptake Inhibitors; Sirolimus; Tapentadol; Thiazoles; Tolvaptan; Triazoles | 2010 |
Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001.
Topics: Apoptosis; Carcinoma; Cell Cycle; Cell Line, Tumor; Eukaryotic Initiation Factor-4E; Everolimus; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; Jurkat Cells; Lymphoma; Models, Biological; Phosphorylation; Proto-Oncogene Proteins c-akt; Sirolimus; Tetrazolium Salts; Thiazoles; TOR Serine-Threonine Kinases | 2011 |
Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Everolimus; Female; Humans; Immunohistochemistry; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Nude; Sirolimus; Stem Cells; Taxoids; Tetrazolium Salts; Thiazoles | 2012 |
Toxicity evaluation of prolonged convection-enhanced delivery of small-molecule kinase inhibitors in naïve rat brainstem.
Topics: Animals; Antineoplastic Agents; Brain Stem; Convection; Dasatinib; Drug Delivery Systems; Everolimus; Female; Infusions, Intraventricular; Phosphorylcholine; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Sirolimus; Thiazoles | 2015 |
Co-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice.
Topics: Animals; Apoptosis; Azepines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Everolimus; Homeodomain Proteins; Imidazoles; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Quinolines; Signal Transduction; Thiazoles; Transcription, Genetic; Triazoles; Vincristine | 2015 |
Comparative Metabolomic Profiling of Hepatocellular Carcinoma Cells Treated with Sorafenib Monotherapy vs. Sorafenib-Everolimus Combination Therapy.
Topics: Annexin A5; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Drug Synergism; Everolimus; Fluorescein-5-isothiocyanate; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolomics; Multivariate Analysis; Niacinamide; Phenylurea Compounds; Sorafenib; Tetrazolium Salts; Thiazoles | 2015 |
Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Everolimus; Hypertension, Pulmonary; Male; Matrix Metalloproteinases; Monocrotaline; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Thiazoles; Vasodilator Agents | 2017 |
Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone.
Topics: Acrylamides; Active Transport, Cell Nucleus; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Everolimus; Exportin 1 Protein; Humans; Hydrazines; Karyopherins; Lymphoma, Non-Hodgkin; Mice, Inbred ICR; Mice, SCID; Oxadiazoles; Prednisone; Protein Kinase Inhibitors; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Time Factors; TOR Serine-Threonine Kinases; Transcription Factor RelA; Triazoles; Tumor Burden; Vincristine; Xenograft Model Antitumor Assays | 2016 |
The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Cycle; Cell Line, Tumor; Chromogranin A; Class I Phosphatidylinositol 3-Kinases; Dose-Response Relationship, Drug; Drug Synergism; Everolimus; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Humans; Pancreas; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, Somatostatin; Signal Transduction; Thiazoles | 2017 |
Effect of combined treatment with a pan-PI3K inhibitor or an isoform-specific PI3K inhibitor and everolimus on cell proliferation in GH-secreting pituitary tumour in an experimental setting.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Everolimus; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Pituitary Neoplasms; Rats; Signal Transduction; Thiazoles | 2018 |
Synergistic Highly Potent Targeted Drug Combinations in Different Pheochromocytoma Models Including Human Tumor Cultures.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line; Drug Screening Assays, Antitumor; Drug Synergism; Everolimus; Female; Humans; Male; Mice; Middle Aged; Pheochromocytoma; Primary Cell Culture; Signal Transduction; Thiazoles | 2019 |
Effect of murine double-minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys.
Topics: Adenocarcinoma, Clear Cell; Animals; Apoptosis; Carcinoma, Renal Cell; Cell Cycle; Cell Proliferation; Disease Models, Animal; Everolimus; Female; Heterografts; Humans; Imidazoles; Kidney; Mice; Ovarian Neoplasms; Peritonitis; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-mdm2; Thiazoles; TOR Serine-Threonine Kinases | 2020 |
ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Estrogen Receptor alpha; Everolimus; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; Piperazines; Protein Isoforms; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Signal Transduction; Sulfonamides; Thiazoles; Thiophenes | 2021 |