Page last updated: 2024-08-21

thiazoles and encorafenib

thiazoles has been researched along with encorafenib in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Deuker, MM; Marsh Durban, V; McMahon, M; Phillips, WA1
Beasley, G; Rossfeld, K; Salama, AK; Turner, MC; Tyler, D1
Avsar, E; Bendell, JC; Chatterjee, A; Delord, JP; Demuth, T; Elez, E; Eskens, FALM; Faris, JE; Jaeger, S; Lenz, HJ; Lolkema, MP; Maharry, K; Schellens, JHM; Schuler, M; Sharma, S; Spreafico, A; Tabernero, J; Tan, E; van Geel, RMJM; Wainberg, ZA; Yaeger, R; Yamada, Y; Yoshino, T1
Anbar, HS; El-Gamal, MI; Jeon, HR; Kwon, D; Lee, BS; Oh, CH; Tarazi, H1
Bernards, R; Boelens, MC; Huijberts, SCFA; Opdam, FL1

Reviews

1 review(s) available for thiazoles and encorafenib

ArticleYear
Can binimetinib, encorafenib and masitinib be more efficacious than currently available mutation-based targeted therapies for melanoma treatment?
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:5

    Topics: Benzamides; Benzimidazoles; Carbamates; Humans; Melanoma; Mutation; Piperidines; Protein Kinase Inhibitors; Proteomics; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-kit; Pyridines; Skin Neoplasms; Sulfonamides; Thiazoles

2017

Trials

1 trial(s) available for thiazoles and encorafenib

ArticleYear
A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic
    Cancer discovery, 2017, Volume: 7, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carbamates; Cetuximab; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Mutation; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Sulfonamides; Thiazoles

2017

Other Studies

4 other study(ies) available for thiazoles and encorafenib

ArticleYear
PI3'-kinase inhibition forestalls the onset of MEK1/2 inhibitor resistance in BRAF-mutated melanoma.
    Cancer discovery, 2015, Volume: 5, Issue:2

    Topics: Animals; Carbamates; Cell Line, Tumor; Cell Proliferation; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Melanoma; Melanoma, Experimental; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Random Allocation; Sulfonamides; Thiazoles

2015
Drug combo beneficial in colorectal cancer.
    Cancer discovery, 2015, Volume: 5, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carbamates; Cetuximab; Colorectal Neoplasms; Humans; Sulfonamides; Thiazoles

2015
Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies.
    Journal of enzyme inhibition and medicinal chemistry, 2020, Volume: 35, Issue:1

    Topics: Antineoplastic Agents; Carbamates; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Imidazoles; Melanoma; Molecular Dynamics Simulation; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Quantitative Structure-Activity Relationship; Sorafenib; Sulfonamides; Thiazoles; Vemurafenib

2020
Mutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/- binimetinib or alpelisib.
    British journal of cancer, 2021, Volume: 124, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biomarkers, Tumor; Carbamates; Cetuximab; Cohort Studies; Colorectal Neoplasms; DNA Mutational Analysis; Drug Resistance, Neoplasm; Female; Humans; Male; Middle Aged; Mutation; Proto-Oncogene Proteins B-raf; Retrospective Studies; Sulfonamides; Thiazoles

2021