thiazoles has been researched along with elacridar in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH | 1 |
| Honkakoski, P; Urtti, A; Vellonen, KS | 1 |
| Beijnen, JH; Hillebrand, MJ; Lagas, JS; Lankheet, N; Rosing, H; Schinkel, AH; van Tilburg, VA; van Waterschoot, RA | 1 |
| Agarwal, S; Chen, C; Chen, Y; Elmquist, WF; Shaik, NM; Yang, Z | 1 |
| Agarwal, S; Decker, SA; Donelson, R; Elmquist, WF; Gallardo, JL; Mittapalli, RK; Ohlfest, JR; Pokorny, JL; Santacruz, KS; Sarkaria, JN; Seiler, C; Zellmer, DM | 1 |
| Elmquist, WF; Mittapalli, RK; Sane, R | 1 |
6 other study(ies) available for thiazoles and elacridar
| Article | Year |
|---|---|
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cattle; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Humans; L-Lactate Dehydrogenase; Multidrug Resistance-Associated Proteins; Oxidation-Reduction; Propionates; Quinolines; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles; Verapamil | 2004 |
Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Brain; Cell Line; Dasatinib; Dogs; Mice; Mice, Knockout; Protein Kinase Inhibitors; Pyrimidines; Tetrahydroisoquinolines; Thiazoles | 2009 |
P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib.
Topics: Acridines; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Cell Line; Cell Membrane Permeability; Dasatinib; Dibenzocycloheptenes; Dogs; Drug Resistance, Neoplasm; Indicators and Reagents; Mass Spectrometry; Mice; Mice, Knockout; Neurons; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Tetrahydroisoquinolines; Thiazoles; Vinblastine | 2009 |
Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Dasatinib; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Humans; Mice; Mice, Knockout; Molecular Targeted Therapy; Oncogenes; Permeability; Pyrimidines; Signal Transduction; Survival Analysis; Tetrahydroisoquinolines; Thiazoles; Tight Junctions; Tissue Distribution; Treatment Outcome; Xenograft Model Antitumor Assays | 2012 |
Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability.
Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Brain; Cell Line; Dasatinib; Dogs; Drug Delivery Systems; Emulsions; Erlotinib Hydrochloride; Humans; Mice; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Solubility; Tetrahydroisoquinolines; Thiazoles | 2013 |