thiazoles has been researched along with e 3040 in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horie, T; Sugiyama, Y; Suzuki, H; Takenaka, O | 2 |
| Komatsu, Y; Minami, N | 1 |
| Horie, T; Kobayashi, K; Sugiyama, Y; Suzuki, H; Takenaka, O | 1 |
| Horie, T; Kato, Y; Kobayashi, K; Niinuma, K; Sugiyama, Y; Suzuki, H; Takenaka, O | 1 |
| Furitsu, H; Iga, T; Kotaki, H; Sawada, Y; Yamada, H | 2 |
| Dabbs, JE; Froehlich, R; Green, CE; Kato, Y; Niinuma, K; Sugiyama, Y; Suzuki, H; Tyson, CA; Weizer, V | 1 |
| Iga, T; Itoh, T; Kotaki, H; Sawada, Y; Yamada, H | 1 |
| Harada, K; Inoue, T; Nagakura, N; Oketani, K | 1 |
| Inoue, T; Murakami, M; Oketani, K | 1 |
| Murakami, M; Murota, M; Oketani, K; Sakai, H; Suzuki, T; Takeguchi, N; Uchiumi, T | 1 |
| Jonker, JW; Kusuhara, H; Mizuno, N; Niwa, T; Sugiyama, Y; Suzuki, H; Suzuki, M; Takeuchi, K | 1 |
| Adachi, Y; Schinkel, AH; Sugiyama, Y; Suzuki, H | 1 |
15 other study(ies) available for thiazoles and e 3040
| Article | Year |
|---|---|
Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.
Topics: Animals; Benzothiazoles; Biliary Tract; Glucuronates; Hepatectomy; Hyperbilirubinemia, Hereditary; Lipoxygenase Inhibitors; Liver; Male; Pyridines; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Species Specificity; Sulfates; Thiazoles; Thromboxane-A Synthase | 1995 |
Synthesis of a novel dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase (E3040) via the direct coupling reaction of hydroquinone with 3-pyridinecarboxaldehyde.
Topics: Benzothiazoles; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Pyridines; Thiazoles; Thromboxane-A Synthase | 1995 |
Kinetic analysis of hepatobiliary transport for conjugated metabolites in the perfused liver of mutant rats (EHBR) with hereditary conjugated hyperbilirubinemia.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Bile; Bile Canaliculi; Biological Transport; Cholagogues and Choleretics; Cytosol; Glucuronates; Hyperbilirubinemia, Hereditary; In Vitro Techniques; Kinetics; Lipoxygenase Inhibitors; Liver; Male; Membranes; Mutation; Protein Binding; Pyridines; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Sulfates; Taurocholic Acid; Thiazoles | 1995 |
Carrier-mediated active transport of the glucuronide and sulfate of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into rat liver: quantitative comparison of permeability in isolated hepatocytes, perfused liver and liver in
Topics: Animals; Benzothiazoles; Biological Transport, Active; Cell Membrane Permeability; Cells, Cultured; Glucuronates; Kinetics; Liver; Male; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sulfuric Acid Esters; Thiazoles | 1997 |
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)benzothiazole glucuronide.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Bile Canaliculi; Biological Transport, Active; Glutathione; Hyperbilirubinemia, Hereditary; Kinetics; Male; Pyridines; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Thiazoles | 1997 |
Mechanism of the uricosuric action of the anti-inflammatory drug E3040 used to treat inflammatory bowel disease I: study using a rat model of hyperuricemia.
Topics: Animals; Benzothiazoles; Disease Models, Animal; Inflammatory Bowel Diseases; Inulin; Kidney Tubules, Proximal; Lipoxygenase Inhibitors; Male; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboxane-A Synthase; Uric Acid; Uricosuric Agents | 1999 |
Primary active transport of organic anions on bile canalicular membrane in humans.
Topics: Adenosine Triphosphate; Adult; Anions; Anti-Infective Agents; Benzothiazoles; Bile Canaliculi; Biological Transport, Active; Cell Membrane; Child; Estradiol; Female; Fluoroquinolones; Glucuronates; Glutathione; Humans; Ion Transport; Leukotriene C4; Male; Middle Aged; Piperazines; Pyridines; Sulfobromophthalein; Taurocholic Acid; Thiazoles | 1999 |
E 3040.
Topics: Animals; Benzothiazoles; Colitis, Ulcerative; Drugs, Investigational; Gastrointestinal Agents; Humans; Inflammatory Bowel Diseases; Lipoxygenase Inhibitors; Pyridines; Rats; Thiazoles; Thromboxane-A Synthase | 1999 |
Mechanism of the uricosuric action of E3040, a drug used to treat inflammatory bowel disease II: study using DBA/2N mice.
Topics: Animals; Benzothiazoles; Gastrointestinal Agents; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred DBA; Pyrazinamide; Pyridines; Thiazoles; Uric Acid; Uricosuric Agents | 1999 |
Effect of anti-inflammatory bowel disease drug, E3040, on urate transport in rat renal brush border membrane vesicles.
Topics: Animals; Benzothiazoles; Biological Transport; Dose-Response Relationship, Drug; Gastrointestinal Agents; Hydroxides; Kidney; Kinetics; Male; Microvilli; Pyridines; Rats; Rats, Wistar; Thiazoles; Uric Acid; Uricosuric Agents | 2000 |
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2001 |
Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide.
Topics: Animals; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Gastrointestinal Agents; Injections, Intravenous; Intestinal Mucosa; Intestine, Large; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Prednisolone; Pyridines; Rats; Rats, Inbred F344; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase; Time Factors | 2001 |
E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl- secretion induced by platelet-activating factor in isolated rat colon.
Topics: Animals; Benzothiazoles; Chlorides; Colon; Enzyme Inhibitors; Female; In Vitro Techniques; Intestinal Mucosa; Lipoxygenase Inhibitors; Organic Anion Transporters; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Wistar; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2002 |
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzothiazoles; Female; Glomerular Filtration Rate; Humans; Hymecromone; Infusions, Intravenous; Injections, Intravenous; Kidney Tubules, Proximal; Membrane Proteins; Mice; Mice, Knockout; Pyridines; Species Specificity; Thiazoles | 2004 |
Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzothiazoles; Breast Neoplasms; Drug Resistance, Multiple; Enterocytes; Gene Deletion; Glucuronides; Hyperbilirubinemia; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Pyridines; Rats; Sulfates; Thiazoles | 2005 |