Page last updated: 2024-08-21

thiazoles and ds-5272

thiazoles has been researched along with ds-5272 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Aonuma, M; Fukutake, S; Kawato, H; Kitagawa, M; Miyazaki, M; Naito, H; Okayama, T; Seki, T; Soga, T; Sugimoto, Y; Uoto, K; Yoshida, K1
Anders, HJ; Fujikura, T; Iwakura, T; Tsuji, T; Yasuda, H1
Asada, S; Fukuyama, T; Goyama, S; Hayashi, Y; Kitamura, T; Liu, X; Matsuda, K; Matsumoto, A; Mizukawa, B; O'Brien, E; Sashida, G; Shibata, T; Takizawa, H; Tamura, M; Tanaka, Y; Wunderlich, M; Yamasaki, S; Yamazaki, S1
Ayabe, T; Fujii, T; Hiraike, H; Honjo, H; Kawata, Y; Kojima, M; Makii, C; Matsumoto, Y; Miyagawa, Y; Nagasaka, K; Oda, K; Oki, S; Osuga, Y; Sone, K; Taguchi, A; Takeuchi, M; Tanikawa, M; Wada-Hiraike, O1

Other Studies

4 other study(ies) available for thiazoles and ds-5272

ArticleYear
Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitor.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Fluorine; Gene Expression; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Binding; Proto-Oncogene Proteins c-mdm2; Pyrrolidines; Sarcoma; Thiazoles; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2015
MDM2 inhibitor ameliorates cisplatin-induced nephropathy via NFκΒ signal inhibition.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:1

    Topics: Acute Kidney Injury; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion Molecules; Cisplatin; Disease Models, Animal; HEK293 Cells; Humans; Imidazoles; Kidney Tubules; Male; Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiazoles; Treatment Outcome

2019
Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
    Nature communications, 2019, 10-25, Volume: 10, Issue:1

    Topics: Animals; B7-H1 Antigen; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Immunotherapy; Inflammation; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Neoplasm Transplantation; Proto-Oncogene Proteins c-mdm2; Thiazoles; Tumor Suppressor Protein p53

2019
Effect of murine double-minute 2 inhibitors in preclinical models of advanced clear cell carcinomas originating from ovaries and kidneys.
    Cancer science, 2020, Volume: 111, Issue:10

    Topics: Adenocarcinoma, Clear Cell; Animals; Apoptosis; Carcinoma, Renal Cell; Cell Cycle; Cell Proliferation; Disease Models, Animal; Everolimus; Female; Heterografts; Humans; Imidazoles; Kidney; Mice; Ovarian Neoplasms; Peritonitis; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-mdm2; Thiazoles; TOR Serine-Threonine Kinases

2020