thiazoles has been researched along with dolastatin 10 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, R; Hamel, E; Pettit, GR | 1 |
| Fantucci, P; Marino, T; Russo, N; Villa, AM | 1 |
| Horgen, FD; Kazmierski, EB; Scheuer, PJ; Westenburg, HE; Yoshida, WY | 1 |
| Bai, R; Copeland, TD; Covell, DG; Hamel, E; Kepler, JA; Nguyen, NY; Pettit, GR; Taylor, GF | 1 |
| Balachandran, R; Day, BW; McPherson, PA; Raccor, BS; Vogt, A; Wang, Z; Wipf, P; Zhu, G | 1 |
| Liu, Y; Luesch, H; Paul, VJ; Taori, K | 1 |
| Engene, N; Luesch, H; Paul, VJ; Salvador-Reyes, LA | 1 |
| Izawa, A; Morita, Y; Nishio, Y; Sakai, C; Sakurada, E; Yokosaka, S | 1 |
8 other study(ies) available for thiazoles and dolastatin 10
| Article | Year |
|---|---|
Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
Topics: Amino Acid Sequence; Animals; Antibiotics, Antineoplastic; Aziridines; Cell Division; Cell Survival; Depsipeptides; Diamines; Drug Interactions; Guanosine Triphosphate; Mice; Mitotic Index; Molecular Sequence Data; Oligopeptides; Organophosphorus Compounds; Thiazoles; Tubulin; Tumor Cells, Cultured; Vinca Alkaloids; Vincristine | 1990 |
Conformational behaviour of the antineoplastic peptide dolastatin-10 and of two mutated derivatives.
Topics: Amino Acids; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Depsipeptides; Hydrogen Bonding; Models, Molecular; Molecular Structure; Mollusca; Mollusk Venoms; Mutation; Oligopeptides; Protein Conformation; Pyrrolidines; Solutions; Structure-Activity Relationship; Thiazoles; Valine; Water | 1995 |
Malevamide D: isolation and structure determination of an isodolastatin H analogue from the marine cyanobacterium Symploca hydnoides.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyanobacteria; Depsipeptides; Drug Screening Assays, Antitumor; Hawaii; Hydrolysis; Inhibitory Concentration 50; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Stereoisomerism; Thiazoles; Tumor Cells, Cultured | 2002 |
Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.
Topics: Animals; Antineoplastic Agents; Binding Sites; Brain; Cattle; Computer Simulation; Cysteine; Depsipeptides; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Guanosine Diphosphate; Kinetics; Ligands; Light; Models, Chemical; Models, Molecular; Oligopeptides; Peptides; Peptides, Cyclic; Photoaffinity Labels; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thiazoles; Time Factors; Tubulin; Ultraviolet Rays | 2004 |
Structure-activity and high-content imaging analyses of novel tubulysins.
Topics: Animals; Cattle; Cell Line, Tumor; Depsipeptides; Glioblastoma; HeLa Cells; Humans; Mitosis; Oligopeptides; Structure-Activity Relationship; Thiazoles; Tubulin; Tubulin Modulators; Vinblastine | 2007 |
Combinatorial strategies by marine cyanobacteria: symplostatin 4, an antimitotic natural dolastatin 10/15 hybrid that synergizes with the coproduced HDAC inhibitor largazole.
Topics: Antimicrobial Cationic Peptides; Antimitotic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Line, Tumor; Cyanobacteria; Depsipeptides; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Peptides; Thiazoles | 2009 |
Targeted natural products discovery from marine cyanobacteria using combined phylogenetic and mass spectrometric evaluation.
Topics: Biological Products; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cyanobacteria; Cytotoxins; Depsipeptides; HCT116 Cells; Humans; Marine Biology; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phylogeny; Thiazoles | 2015 |
Synthesis and evaluation of novel dolastatin 10 derivatives for versatile conjugations.
Topics: Alcohols; Amines; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Depsipeptides; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mice; Molecular Structure; Structure-Activity Relationship; Sulfhydryl Compounds; Thiazoles; Tubulin | 2018 |