thiazoles has been researched along with dinoprostone in 182 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (7.14) | 18.7374 |
| 1990's | 25 (13.74) | 18.2507 |
| 2000's | 89 (48.90) | 29.6817 |
| 2010's | 53 (29.12) | 24.3611 |
| 2020's | 2 (1.10) | 2.80 |
| Authors | Studies |
|---|---|
| Fatimi, J; Lagorce, JF; Lakhdar, M; Nefaoui, S; Raby, C | 1 |
| Baldari, CT; Donati, D; Macchia, G; Massone, A; Parente, L; Telford, JL | 1 |
| Burch, RM | 1 |
| Bender, PE; Griswold, DE; Hanna, N; Hillegass, L; Hoffstein, S; Marshall, PJ; Webb, EF | 1 |
| Carlei, F; D'Alessandro, MD; Lezoche, E; Lomanto, D; Mariani, P; Martelli, A; Nardovino, M; Speranza, V; Vagni, V | 1 |
| Braquet, P; Neuwirth, R; Satriano, JA; Schlondorff, D; Singhal, P | 1 |
| Krüger, S; Schlegel, W | 1 |
| Steel, G; Wallace, JL; Whittle, BJ | 1 |
| Kogo, H; Matsudaira, T; Satoh, T | 1 |
| Blaine, EH; Seymour, AA | 1 |
| Harada, M; Maeno, H; Terai, M | 1 |
| Hemady, Z; Kiselis, I; Lima, M; Matloff, S; Rocklin, RE | 1 |
| Kumahara, Y; Masugi, F; Ogihara, T; Otsuka, A; Saeki, S | 1 |
| Bito, LZ | 1 |
| Dodge, GR; Rappaport, RS | 1 |
| Kassis, S; Lee, JC; Prabhakar, U | 1 |
| Hibi, S; Inoue, T; Kawahara, T; Kobayashi, N; Murakami, M; Numata, H; Okamoto, Y; Oketani, K; Shinoda, M; Tagami, K | 1 |
| Abe, H; Aida, T; Sakuma, S; Sawamura, Y; Suzuki, K; Tada, M; Taniguchi, N | 1 |
| Bögel, R; Engelhardt, G; Schnitzer, C; Utzmann, R | 1 |
| Bögel, R; Engelhardt, G; Schnitzler, C; Utzmann, R | 1 |
| Joller, PW; Lentzen, H; Menrad, JM; Parnham, MJ; Pfüller, U; Schwarz, T; Weyhenmeyer, R | 1 |
| Benoit, RR; Lantz, ME; O'Brien, WF; Spaziani, EP | 1 |
| Bassleer, C; Geenen, V; Magotteaux, J; Malaise, M | 1 |
| Frölich, JC; Stichtenoth, DO; Wagner, B | 2 |
| Fang, GD; Guerrant, RL; Marcinkiewicz, M; Sarosiek, J; Thielman, NM | 1 |
| Rainsford, KD; Smith, FC; Ying, C | 1 |
| Abramovitz, M; Ford-Hutchinson, AW; Metters, KM; Wright, DH | 1 |
| Engelhardt, G; Mauz, A; Pairet, M; Schierok, H; Trummlitz, G; van Ryn, J | 1 |
| Armstrong, G; Lipscomb, GR; Rees, WD; Wallis, N | 1 |
| Fujiwara, T; Horikoshi, H; Ikeda, K; Matsuda, K; Ohsawa, T; Okuno, A; Takahashi, S; Ushiyama, S | 1 |
| DuBois, RN; Goldman, AP; Lamps, LW; Morrow, JD; Pairet, M; Sheng, H; Williams, CS; Williams, VP | 1 |
| Bornemeier, DA; Chan, K; Connor, DT; Doubleday, R; Dyer, RD; Gilbertsen, RB; Guglietta, A; Roth, BD; Schrier, DJ; Sercel, AD; Song, Y; Sorenson, RJ; Unangst, PC | 1 |
| Gebicke-Haerter, PJ; Kakimura, J; Kitamura, Y; Matsuoka, Y; Nomura, Y; Taniguchi, T | 1 |
| Gilbertsen, R; Guglietta, A; Kraus, ER; Lesch, CA; Sanchez, B | 1 |
| Di Giamberardino, M; Panara, MR; Patrignani, P; Patrono, C; Renda, G; Rotondo, MT; Santini, G; Sciulli, MG; Seta, F; Tacconelli, S | 1 |
| Dwyer, JE; Gross, JM; Knox, FG | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Sliwowski, Z; Stachura, J | 1 |
| Mitchell, JA; Pepper, JR; Stanford, SJ | 1 |
| Hashiramoto, A; Kohno, M; Kondo, M; Kusaka, Y; Sano, H; Tsubouchi, Y; Yamada, R | 1 |
| Arimura, A; Hori, Y; Inagaki, M; Jyoyama, H; Kakudo, S; Kato, M; Kawai, S; Kobayashi, M; Koizumi, K; Matsumoto, S; Ohno, K; Ono, T; Suzuki, R; Tsuri, T; Yamada, K; Yasui, K | 1 |
| Atweh, SF; Dardenne, M; Jabbur, SJ; Kanaan, SA; Saadé, NE; Safieh-Garabedian, B | 1 |
| Morita, I; Murota, S; Sakaguchi, K | 1 |
| Benn, SJ; Conlon, P; Kay-Mugford, P; LaMarre, J | 1 |
| Jancar, S; Marzagão Barbuto, JA; Ribeiro-Dias, F; Tsujita, M | 1 |
| Alarcón de la Lastra, C; La Casa, C; Martín, MJ; Motilva, V; Villegas, I | 1 |
| Carballosa Coré-Bodelier, VM; Van Delft, JL; van Haeringen, NJ; van Sorge, AA | 1 |
| Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K | 1 |
| Adamson, L; Bocking, AD; Challis, JR; Fraser, M; Lye, SJ; McKeown, KJ; Riggs, KW; Rurak, D; Small, C | 1 |
| Harada, Y; Hatanaka, K; Kawamura, M; Ogino, K; Ohno, T | 1 |
| Akuzawa, S; Ito, H; Iwaoka, K; Kamato, T; Kiso, T; Miyata, K; Nagakura, Y; Naitoh, Y; Sakai, H; Suzuki, M; Yamaguchi, T; Yamano, M; Yuki, H | 1 |
| Chadee, K; Ford-Hutchinson, AW; Metters, KM; Wright, DH | 1 |
| Hagen, TJ; Hallinan, EA; Savage, MA; Stapelfeld, A; Tsymbalov, S | 1 |
| Bertone, AL; Hardy, J; Moses, VS; Weisbrode, SE | 1 |
| Chan, CP; Chang, MC; Chen, RS; Chen, YJ; Jeng, JH; Lan, WH; Wu, HL | 1 |
| Chang, DM; Hsieh, TC; Hsu, CT; Kuo, SY; Young, TH | 1 |
| Hla, T; Inoue , K; Kawahito, Y; Kohno, M; Sano, H; Tsubouchi, Y | 1 |
| Bäumer, W; Kietzmann, M | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Ptak, A; Sliwowski, Z | 1 |
| Harada, K; Inoue, T; Nagakura, N; Oketani, K | 1 |
| Norvell, SM; Pavalko, FM; Ponik, SM; Sawyer, SJ | 1 |
| Inoue, T; Murakami, M; Oketani, K | 1 |
| Marathe, GK; McIntyre, TM; Pontsler, AV; St Hilaire, A; Zimmerman, GA | 1 |
| Goto, T; Ochi, T | 1 |
| Alvi, SA; Bennett, PR; Brown, NL; Elder, MG; Sullivan, MH | 1 |
| Elverdin, JC; Faletti, A; Lomniczi, A; McCann, SM; Mohn, C; Rettori, V; Scorticati, C | 1 |
| Baik, EJ; Kim, EJ; Kwon, KJ; Lee, SH; Moon, CH; Park, JY | 1 |
| De La Lastra, CA; La Casa, C; Martín, MJ; Motilva, V; Villegas, I | 1 |
| Hase, T; Kawahito, Y; Mitsuhashi, M; Nakatani, T; Sano, H; Segawa, Y; Wada, S; Yoshimura, R | 1 |
| Ang, KK; Milas, L; Nakata, E; Newman, RA; Raju, U; Yang, P | 1 |
| Diez-Ortego, I; Egido, J; Herrero-Beaumont, G; Largo, R; López-Armada, MJ; Palacios, I; Sánchez-Pernaute, O | 1 |
| Hishinuma, T; Mizugaki, M; Suzuki, H; Tomioka, Y; Yamazaki, T; Yokoo, T | 1 |
| Dosoretz, A; Holland, JF; Kirschenbaum, A; Levine, AC; Liu, XH; Lu, M; Yao, S | 1 |
| Budsberg, SC; Harmon, BG; Jones, CJ; Streppa, HK | 1 |
| Cho, H; Tai, HH | 1 |
| Corbett, L; Knox, AJ; Nie, M; Pang, L | 1 |
| Al-Awadi, FM; Anim, JT; Haridas, S; Khan, I; Thomas, N | 1 |
| Cardile, V; Gentile, B; Geronikaki, A; Panico, AM; Ronsisvalle, G | 1 |
| Calvo, JR; Carrillo-Vico, A; García-Mauriño, S; Guerrero, JM | 1 |
| Faletti, AG; Farina, M; Lomniczi, A; Mohn, C; Rettori, V | 1 |
| Han, SM; Jang, MH; Kim, CJ; Kim, EH; Kim, KA; Lee, JS; Lim, S; Park, HJ; Shin, I; Shin, MC | 1 |
| Baba, T; Inagaki, M; Iwatani, K; Jyoyama, H; Kobayashi, M; Matsumoto, S; Ohkawa, T; Ono, T; Touchi, A; Tsuri, T; Yamada, K | 1 |
| Inagaki, M | 1 |
| Bennett, P; Pan, H; Sawdy, R; Sullivan, M | 1 |
| de la Lastra, CA; Herrerías, JM; La Casa, C; Martín, MJ; Motilva, V; Villegas, I | 1 |
| Chen, YC; Hsu, KC; Ko, CH; Shen, SC | 1 |
| Alfaidy, N; Challis, JR; Martin, R; Mirazi, N | 1 |
| Baldi, A; Davio, C; Fernández, N; Legnazzi, BL; Monczor, F; Riveiro, ME; Shayo, C | 1 |
| Eling, TE; Hong, JS; Langenbach, R; Liu, B; Liu, Y; Qin, L; Taniura, S; Wang, T; Wilson, B | 1 |
| Cella, M; Farina, M; Franchi, A; Ribeiro, M | 1 |
| Creutzig, U; Langebrake, C; Puhlmann, U; Reinhardt, D; Ruedell, G; Schaefer, D; Schuermann, P; Vorwerk, H; Ziemann, C | 1 |
| Kim, HJ; Kim, MK; Lee, MW; Paek, IN; Shim, JG; Yeom, SH | 1 |
| Baek, SH; Chai, KY; Chung, HT; Jang, SI; Kim, YJ; Kwak, GB; Kwak, KC; Kwon, TO; Lee, WY; Yun, YG | 1 |
| Beretta, C; Cavalli, M; Garavaglia, G | 1 |
| Cunha, FQ; Michelin, MA; Silva, JS | 1 |
| Han, S; Ritzenthaler, JD; Roman, J; Wingerd, B | 1 |
| Choi, JW; Chung, WY; Jung, HJ; Kim, SG; Kim, WB; Lee, KT; Nam, JH; Park, HJ; Park, KK; Won, JH | 1 |
| Hosono, K; Ishiguro, N; Naruse, T; Nishida, Y | 1 |
| Choi, WS; Han, JW; Kang, JK; Lee, HW; Lee, KR; Shin, SG | 1 |
| Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Ali, MA; Carreon, P; Choy, H; Mukhopadhyay, P; Nandi, A; Saha, D | 1 |
| Aisemberg, J; Billi, S; Cella, M; Farina, M; Franchi, AM; Ribeiro, ML; Sordelli, MS | 1 |
| Dragunow, M; Gibbons, HM | 1 |
| Bosetti, F; Silva, AC; Stefanovic, B | 1 |
| Choi, SK; Han, YN; Lee, KT; Park, YM; Ryu, JH; Won, JH; Yun, KJ | 1 |
| Han, C; Wu, T; Xu, L | 1 |
| Becker, TL; Gambero, A; Maróstica, M; Pedrazzoli, J | 1 |
| Chang, HK; Ham, DH; Kim, CJ; Kim, H; Kim, YS; Lee, H; Lee, JW; Lee, MH; Park, HK; Shin, MS; Yang, HY | 1 |
| Cho, SJ; Jung, HC; Kim, JS; Kim, N; Song, IS | 1 |
| Hu, JH; Zhu, XZ | 1 |
| Futagami, M; Mizunuma, H; Shigeto, T; Xin, B; Yokoyama, Y | 1 |
| Han, AR; Kim, JB; Lee, IS; Lee, J; Lee, KT; Nam, JW; Seo, EK; Shim, CK | 1 |
| Chung, SH; Han, EJ; Ren, J | 1 |
| Baiza-Durán, LM; Cruz, R; González, JR; Quintana-Hau, JD; Tornero-Montaño, R; Vega, L | 1 |
| Cho, JY; Kim, BH | 1 |
| Abdalla, GK; Castro, EC; Faria, GE; Michelin, MA; Reis, MA; Silva, KT | 1 |
| Fosse, TK; Haga, HA; Haugejorden, G; Hormazabal, V; Horsberg, TE; Ranheim, B | 1 |
| Ara, T; Fujinami, Y; Hattori, T; Imamura, Y; Maeda, Y; Wang, PL | 1 |
| Fujimura, T; Harada, S; Hattori, T; Miwa, K; Oba, M; Sasaki, S | 1 |
| Fujimura, T; Harada, S; Hattori, T; Miwa, K; Oba, M; Ohta, T; Oyama, K; Sasaki, S | 1 |
| Baumruker, T; Billich, A; Reuschel, R; Urtz, N | 1 |
| Hopfgarten, F; Kietzmann, M; Pittermann, W | 1 |
| Han, S; Ritzenthaler, JD; Roman, J | 1 |
| Cho, YW; Choi, JH; Kim, JY; Kim, SY; Lee, KT; Ryu, JH; Shin, JS | 1 |
| Alfieri, AB; Linares-Fernández, B | 1 |
| Ha, BJ; Kim, ID | 1 |
| Gilmour, MA; Lehenbauer, TW | 1 |
| Bility, MT; Gonzalez, FJ; Kang, BH; Peters, JM; Zhu, B | 1 |
| Borer, L; Jung, M; King, JN; Lees, P; Rudaz, C; Seewald, W | 1 |
| do Prado, JC; Kuehn, CC; Oliveira, LG; Santos, CD; Toldo, MP | 1 |
| Kim, EK; Kim, JH; Lee, HB; Lee, J; Shin, JH | 1 |
| Hsu, KY; Huang, CJ; Lee, JJ; Tsai, PS; Wang, TY | 1 |
| Buduneli, E; Buduneli, N; Cetin, EO; Kirilmaz, L; Kütükçüler, N | 1 |
| Borda, E; Busch, L; Miozza, V; S-Borda, L | 1 |
| Budsberg, SC; Goodman, LA; Reynolds, LR; Torres, BT | 1 |
| Cella, M; Di Girolamo, G; Dominguez Rubio, AP; Farina, MG; Franchi, AM; Ribeiro, ML | 1 |
| Kim, B; Kim, H; Kim, HJ; Kwon, UH; Lee, HM; Moon, ES; Moon, SH; Park, JO | 1 |
| Fortak-Michalska, M; Jurewicz, A; Matysiak, M; Orlowski, W; Selmaj, K | 1 |
| Chen, L; Lee, DS; Lee, JM; Noh, AL; Park, H; Yim, M; Zheng, T | 1 |
| Liu, ML; Liu, X; Pei, LC; Zhang, YN; Zhang, YQ | 1 |
| Archibald, KE; Clarke, EO; Gjeltema, JL; Lewbart, GA; Minter, LJ; Posner, LP | 1 |
| Chan, CP; Chang, HH; Chang, MC; Huang, GF; Jeng, JH; Lin, PS; Wang, TM; Wang, YL | 1 |
| Chang, HH; Davis, A; Dietrich, J; Gokhale, V; Hulme, C; Medda, F; Meuillet, EJ; Smith, B | 1 |
| Gilmour, MA; Payton, ME | 1 |
| Amin, HA; Edfawy, M; Hamed, AA; Hassan, MH; Mansour, A | 1 |
| Hofer, M; Hoferová, Z; Komůrková, D; Pospíšil, M; Weiterová, L | 1 |
| Keene, CD; Li, X; Montine, KS; Montine, TJ; Rose, SE | 1 |
| Hyun, JW; Jung, E; Lee, J; Park, D | 1 |
| Chen, CH; Hsu, KY; Huang, CJ; Shih, PC | 1 |
| Choi, HK; Kang, KW; Quyen, BT | 1 |
| Allen, K; Badino, P; Bergamasco, L; Bertolotti, L; Coetzee, JF; Dockweiler, J; Edwards-Callaway, LN; Fraccaro, E; Glynn, H; Kukanich, B; Odore, R | 1 |
| Båge, T; Georgsson, P; Gustafsson, A; Jansson, L; Jönsson, J; Kats, A; Lindberg, C; Näsström, K; Quezada, HC; Yucel-Lindberg, T | 1 |
| Breyer, RM; Chitteti, BR; Czader, M; Farag, SS; Ferraro, F; Guise, TA; Hoggatt, AF; Hoggatt, J; Hu, P; Milne, GL; Mohammad, KS; Pelus, LM; Poteat, BA; Scadden, DT; Serezani, CH; Silberstein, L; Singh, P; Speth, JM; Srour, EF; Stilger, KN; Wong, FK | 1 |
| Chang, LY; Chen, YT; Hung, SL; Lai, YL; Lee, NG | 1 |
| Allen, KA; Bergamasco, L; Coetzee, JF; Dockweiler, J; Edwards-Callaway, LN; Fraccaro, E; Glynn, H; Jones, M; KuKanich, B; Lin, H; Wang, C | 1 |
| Abe, S; Honma, S; Mitazaki, S; Nakamura, K; Shinohara, M; Takahashi, N; Yoshida, M | 1 |
| Arancibia, R; Martínez, J; Maturana, C; Salazar, JC; Silva, D; Smith, PC; Tapia, C; Tobar, N | 1 |
| Hosoya, K; Kim, S; Oh, N; Okumura, M | 1 |
| Ahn, JY; Cho, CH; Cho, SW; Choi, J; Choi, SY; Han, AR; Kim, EA | 1 |
| Abd-Allah, GM; Ghobara, M; Hassan, MH | 1 |
| Olsson, PE; Pradhan, A | 1 |
| Atli, O; Burukoglu, D; Ilgin, S; Perk, BO; Uzun, B | 1 |
| Aly, H; Attia, SM; Bahashwan, SA; El-Beshbishy, HA; Ghobara, MM; Hassan, MH | 1 |
| Barbayianni, E; Constantinou-Kokotou, V; Dennis, EA; Feuerherm, AJ; Johansen, B; Kokotos, G; Magrioti, V; Nguyen, T; Shah, I; Sæther, M | 1 |
| Baldwin, LG; Bates, JL; Coetzee, JF; Karriker, LA; Lee, CJ; Pertzborn, KM; Stock, ML; Wang, C; Wulf, LW | 1 |
| Lazarus, M; Oishi, Y; Saper, CB; Scammell, TE; Urade, Y; Yoshida, K | 1 |
| Badran, B; Eid, AA; El Hachem, N; El-Achkar, GA; Fayyad-Kazan, H; Habib, A; Hachem, A; Hamade, E; Hammoud, S; Hirz, T; Jouni, M; Khalaf, A; Merhi, RA; Mrad, MF | 1 |
| Cardenas, R; Fernandez, AC; Guevara, C; Suarez-Roca, H | 1 |
| Amar, E; Dolkart, O; Marmor, S; Shapira, S; Steinberg, EL; Weinbroum, AA | 1 |
| Boitano, S; Burgos-Vega, CC; Dussor, G; Hassler, SN; Price, TJ; Quinn, TL; Sorge, RE; Tillu, DV; Vagner, J | 1 |
| Fernández-Martínez, AB; Lucio-Cazaña, J | 1 |
| Allegretti, M; Aramini, A; Benigni, F; Bettiga, A; Bianchini, G; Bovolenta, S; Brandolini, L; Castiglione, F; Colciago, G; Hedlund, P; Mistretta, FA; Montorsi, F; Russo, A; Russo, R | 1 |
| Allegretti, M; Alves-Filho, JC; Aramini, A; Bianchini, G; Brandolini, L; Cunha, FQ; Cunha, TM; Lopes, AH; Silva, RL; Teixeira, MM; Verri, WA; Zaperlon, AC | 1 |
| Andersson, G; Concha Quezada, H; Kats, A; Koro, C; Norgård, M; Wondimu, Z; Yucel-Lindberg, T | 1 |
| Dong, X; Li, J; Li, T; Liu, F; Sun, X; Wang, F; Wang, X; Wei, H; Xiu, P; Xu, Z; Zhong, J | 1 |
| Chen, Q; Kuang, S; Luo, Y; Ma, J; Mai, S; Tian, X; Xue, L; Yang, J; Yang, Y | 1 |
| Chen, Q; He, Q; Hu, X; Kuang, S; Liang, G; Luo, Y; Ma, J; Mai, S; Tian, X; Wang, H; Yang, J; Yang, Y | 1 |
| Chang, CY; Chang, YY; Huang, CJ; Huang, IT; Kao, MC; Peng, TC | 1 |
| Bourn, J; Cekanova, M | 1 |
| Andersson, G; Desai, S; Gerasimcik, N; Grenlöv, S; Kats, A; Lagnöhed, E; Näreoja, T; Nederberg, J; Yucel-Lindberg, T | 1 |
| An, HJ; Cheon, SY; Cominguez, DC; Lee, DS; Lee, S; Park, YJ; Zhang, Z | 1 |
| Gardhouse, SM; Hocker, SE; Kleinhenz, MD; Montgomery, SR; Rooney, TA; Sarvi, JY; Weeder, MM | 1 |
3 review(s) available for thiazoles and dinoprostone
| Article | Year |
|---|---|
[Studies on the new antiarthritic drug candidate S-2474].
Topics: Animals; Antirheumatic Agents; Cyclic S-Oxides; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Drug Design; Humans; Interleukin-1; Isoenzymes; Leukotriene B4; Lipoxygenase Inhibitors; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship; Thiazoles | 2003 |
Stimulatory action of cyclooxygenase inhibitors on hematopoiesis: a review.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Feedback, Physiological; Gamma Rays; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; Meloxicam; Mice; Myelopoiesis; Thiazines; Thiazoles | 2012 |
Antagonism of neuronal prostaglandin E(2) receptor subtype 1 mitigates amyloid β neurotoxicity in vitro.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Calcium Channel Blockers; Cell Line, Tumor; Cells, Cultured; Coloring Agents; Dinoprostone; Humans; Hydrazines; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Nimodipine; Oxazepines; Peptide Fragments; Prostaglandin Antagonists; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles | 2013 |
11 trial(s) available for thiazoles and dinoprostone
| Article | Year |
|---|---|
Action of famotidine and ranitidine on prostaglandin E2 (PGE2) content of fundic and duodenal mucosa in duodenal ulcer patients.
Topics: Adult; Dinoprostone; Duodenal Ulcer; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Intestinal Mucosa; Male; Middle Aged; Prostaglandins E; Random Allocation; Ranitidine; Thiazoles | 1987 |
Effects of meloxicam and indomethacin on cyclooxygenase pathways in healthy volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Indomethacin; Meloxicam; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Therapeutic Equivalency; Thiazines; Thiazoles; Thromboxane B2 | 1997 |
Gastrointestinal tolerability of meloxicam and piroxicam: a double-blind placebo-controlled study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Duodenum; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Meloxicam; Piroxicam; Thiazines; Thiazoles; Time Factors | 1998 |
Effect of selective inhibition of the inducible cyclooxygenase on renin release in healthy volunteers.
Topics: Adolescent; Adult; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Female; Furosemide; Gas Chromatography-Mass Spectrometry; Humans; Indomethacin; Isoenzymes; Meloxicam; Middle Aged; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Reference Values; Renin; Thiazines; Thiazoles | 1998 |
Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects.
Topics: Adult; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; In Vitro Techniques; Isoenzymes; Male; Meloxicam; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Thiazines; Thiazoles; Thromboxane B2 | 1999 |
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
Endoscopic comparison of the gastroduodenal safety and the effects on arachidonic acid products between meloxicam and piroxicam in the treatment of osteoarthritis.
Topics: Adult; Aged; Arachidonic Acid; Cyclooxygenase Inhibitors; Digestive System; Dinoprostone; Double-Blind Method; Endoscopy, Digestive System; Female; Gastric Juice; Humans; Leukotriene B4; Male; Meloxicam; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Piroxicam; Safety; Thiazines; Thiazoles; Thromboxane B2 | 2001 |
Comparison of tepoxalin, carprofen, and meloxicam for reducing intraocular inflammation in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dinoprostone; Dog Diseases; Dogs; Meloxicam; Pyrazoles; Thiazines; Thiazoles; Uveitis, Anterior | 2009 |
Clinical findings and gingival crevicular fluid prostaglandin E2 and interleukin-1-beta levels following initial periodontal treatment and short-term meloxicam administration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dinoprostone; Double-Blind Method; Female; Gingival Crevicular Fluid; Humans; Interleukin-1beta; Male; Meloxicam; Middle Aged; Periodontitis; Placebos; Thiazines; Thiazoles | 2010 |
Effects of intramuscular meloxicam administration on prostaglandin E2 synthesis in the North American bullfrog (Rana catesbeiana).
Topics: Animals; Dinoprostone; Gene Expression Regulation; Injections, Intramuscular; Meloxicam; Rana catesbeiana; Thiazines; Thiazoles | 2011 |
Comparison of the effects of IV administration of meloxicam, carprofen, and flunixin meglumine on prostaglandin E(2) concentration in aqueous humor of dogs with aqueocentesis-induced anterior uveitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Carbazoles; Clonixin; Dinoprostone; Dog Diseases; Dogs; Female; Injections, Intravenous; Male; Meloxicam; Thiazines; Thiazoles; Uveitis, Anterior | 2012 |
168 other study(ies) available for thiazoles and dinoprostone
| Article | Year |
|---|---|
Synthesis and anti-inflammatory activity of 2-pyridyl-2-thiobenzothiazole derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cattle; Dinoprostone; Edema; Free Radicals; Humans; In Vitro Techniques; Indomethacin; Male; Rats; Rats, Wistar; Synovial Fluid; Thiazoles | 1992 |
Induction of gene expression by IL-1 in NIH 3T3 cells. Possible requirement of protein kinase C activity and independence from arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Interleukin-1; Lipoxygenase Inhibitors; Mice; Protein Kinase C; Pyrimidinones; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Diacylglycerol in the synergy of bradykinin and thrombin stimulation of prostaglandin synthesis.
Topics: Animals; Bradykinin; Cyclohexanones; Diacylglycerol Kinase; Diglycerides; Dinoprostone; Drug Synergism; Fibroblasts; Glycerides; Mice; Mice, Inbred BALB C; Phosphotransferases; Pyrimidinones; Thiazoles; Thrombin; Time Factors | 1989 |
Inhibition of inflammatory cell infiltration by bicyclic imidazoles, SK&F 86002 and SK&F 104493.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis, Leukocyte; Cyclophosphamide; Dinoprostone; Ear Diseases; Edema; Eicosanoids; Imidazoles; Inflammation; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Peritonitis; Pyridines; Thiazoles | 1989 |
Effect of platelet activating factor antagonists on cultured rat mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Cells, Cultured; Dinoprostone; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Glomerular Mesangium; Lactones; Lignans; Male; Plant Extracts; Platelet Activating Factor; Prostaglandins E; Rats; Thiazoles | 1987 |
Prostaglandin-E2 9-ketoreductase from human uterine decidua vera.
Topics: Acetates; Chromatography, High Pressure Liquid; Decidua; Dinoprost; Dinoprostone; Female; Humans; Indomethacin; Kinetics; Molecular Weight; NADP; Progesterone; Prostaglandins E; Prostaglandins F; Thiazoles | 1986 |
Gastrointestinal plasma leakage in endotoxic shock. Inhibition by prostaglandin E2 and by a platelet-activating factor antagonist.
Topics: Animals; Blood Pressure; Blood Proteins; Digestive System; Dinoprostone; Male; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Shock, Septic; Thiazoles | 1987 |
A possible role of antihypertensive polar renomedullary lipid (APRL) and prostaglandin E2 in the kidney in the antihypertensive action of pindolol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dinoprostone; Electrolytes; Indomethacin; Kidney; Male; Phospholipid Ethers; Pindolol; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred SHR; Thiazoles | 1985 |
Renal vasodilation by a prostaglandin analog during dopaminergic and alpha-adrenergic blockade.
Topics: Animals; Aporphines; Blood Flow Velocity; Blood Pressure; Dinoprostone; Dogs; Dopamine; Female; Male; Phenoxybenzamine; Prostaglandins E; Renal Circulation; Thiazoles; Thiazolidines; Vascular Resistance; Vasodilator Agents | 1983 |
Effect of a new potent H2-receptor antagonist 3[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2- sulfamoylpropionamidine (YM-11170) on gastric mucosal histamine-sensitive adenylate cyclase from guinea pig.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Dinoprostone; Dose-Response Relationship, Drug; Famotidine; Gastric Mucosa; Guinea Pigs; Hippocampus; Histamine; Histamine H2 Antagonists; Male; Prostaglandins E; Thiazoles | 1983 |
Correction of an in vitro immunoregulatory defect in atopic subjects by the immunostimulating drug fanetizole mesylate (CP-48,810).
Topics: Adjuvants, Immunologic; Adolescent; Adult; Asthma; Cells, Cultured; Child; Concanavalin A; Dermatitis, Atopic; Dinoprostone; Eczema; Female; Histamine; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Immunoglobulin G; Lymphocyte Activation; Male; Middle Aged; Monocytes; Prostaglandins E; Rhinitis; T-Lymphocytes, Regulatory; Thiazoles | 1984 |
The role of antihypertensive polar renomedullary lipid in the pathogenesis of hypertension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dinoprostone; Dogs; Epoprostenol; Female; Histamine; Hypertension, Renal; Kidney; Kidney Medulla; Male; Norepinephrine; Phospholipid Ethers; Platelet Activating Factor; Prostaglandins E; Rats; Rats, Inbred Strains; Thiazoles | 1984 |
Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds.
Topics: Animals; Carbachol; Cats; Dinoprost; Dinoprostone; Epoprostenol; Female; Intraocular Pressure; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins F, Synthetic; Thiazoles; Thiazolidines; Timolol | 1984 |
Prostaglandin E inhibits the production of human interleukin 2.
Topics: Acetates; Alprostadil; Cell Adhesion; Dinoprost; Dinoprostone; Female; Humans; Indomethacin; Interleukin-2; Lymphokines; Male; Prostaglandins A; Prostaglandins E; Prostaglandins F; Thiazoles | 1982 |
Inhibition of interleukin-1 (IL-1) and tumor necrosis factor (TNF) production by pyridinyl imidazole compounds is independent of cAMP elevating mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclic AMP; Dinoprostone; Escherichia coli; Humans; Imidazoles; Interleukin-1; Lipopolysaccharides; Monocytes; Thiazoles; Tumor Necrosis Factor-alpha | 1993 |
Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives.
Topics: Animals; Blood Platelets; Cells, Cultured; Colitis; Dinoprostone; Disease Models, Animal; Humans; Leukotriene B4; Lipoxygenase Inhibitors; Male; Peritoneal Cavity; Rats; Rats, Inbred F344; Sheep; Structure-Activity Relationship; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 1994 |
Responses of human glioblastoma cells to human natural tumor necrosis factor-alpha: susceptibility, mechanism of resistance and cytokine production studies.
Topics: Cell Division; Colony-Forming Units Assay; Coloring Agents; Cytokines; Dinoprostone; Drug Resistance; Glioma; Humans; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Meloxicam: influence on arachidonic acid metabolism. Part 1. In vitro findings.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Brain; Cattle; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Guinea Pigs; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Meloxicam; Placenta; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Thiazines; Thiazoles | 1996 |
Meloxicam: influence on arachidonic acid metabolism. Part II. In vivo findings.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Brain; Convulsants; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gastric Juice; Inflammation; Isoenzymes; Kidney; Leukotriene B4; Male; Meloxicam; Mice; Pentylenetetrazole; Pleurisy; Rats; Stomach; Thiazines; Thiazoles | 1996 |
Stimulation of cytokine production via a special standardized mistletoe preparation in an in vitro human skin bioassay.
Topics: Biological Assay; Cell Count; Cytokines; Dinoprostone; Humans; Interleukin-1; Interleukin-6; L-Lactate Dehydrogenase; Limulus Test; Mistletoe; Plant Extracts; Plant Preparations; Plant Proteins; Plants, Medicinal; Reproducibility of Results; Ribosome Inactivating Proteins, Type 2; Skin; Tetrazolium Salts; Thiazoles; Toxins, Biological | 1996 |
The induction of cyclooxygenase-2 (COX-2) in intact human amnion tissue by interleukin-4.
Topics: Amnion; Cell Survival; Colorimetry; Coloring Agents; Culture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Evaluation Studies as Topic; Female; Humans; Interleukin-4; Isoenzymes; Membrane Proteins; Obstetric Labor, Premature; Pregnancy; Prostaglandin-Endoperoxide Synthases; Tetrazolium Salts; Thiazoles | 1996 |
Effects of meloxicam compared to acetylsalicylic acid in human articular chondrocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cartilage, Articular; Cells, Cultured; Collagen; Culture Media, Conditioned; Dinoprostone; DNA; Humans; Meloxicam; Proteoglycans; Thiazines; Thiazoles | 1997 |
Role of platelet-activating factor in Chinese hamster ovary cell responses to cholera toxin.
Topics: Alprostadil; Animals; Bucladesine; Cell Size; CHO Cells; Cholera Toxin; Cricetinae; Cyclic AMP; Cycloheximide; Dactinomycin; Dinoprostone; Diterpenes; Ginkgolides; Humans; Lactones; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles | 1997 |
Effects of meloxicam, compared with other NSAIDs, on cartilage proteoglycan metabolism, synovial prostaglandin E2, and production of interleukins 1, 6 and 8, in human and porcine explants in organ culture.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Dinoprostone; Humans; Hydrocortisone; Indomethacin; Interleukin-1; Interleukin-6; Interleukin-8; Interleukins; Meloxicam; Organ Culture Techniques; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Swine; Synovial Fluid; Thiazines; Thiazoles | 1997 |
Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.
Topics: Adenine Nucleotides; Benzoates; Binding, Competitive; Cell Line; Cyclic AMP; Dinoprostone; Guanine Nucleotides; Humans; Kinetics; Receptors, Immunologic; Receptors, Prostaglandin; Recombinant Proteins; Thiazoles; Thiazolidines; Tritium | 1998 |
Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4'-isomer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Isoenzymes; Male; Meloxicam; Prostaglandin-Endoperoxide Synthases; Rats; Stomach Ulcer; Thiazines; Thiazoles | 1998 |
Troglitazone, a new antidiabetic agent possessing radical scavenging ability, improved decreased skin blood flow in diabetic rats.
Topics: Animals; Aorta, Thoracic; Blood Glucose; Chromans; Diabetes Mellitus, Experimental; Dinoprostone; Epoprostenol; Fibroblasts; Free Radical Scavengers; Guinea Pigs; Hindlimb; Hypoglycemic Agents; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Rats; Rats, Sprague-Dawley; Rats, Wistar; Regional Blood Flow; Skin; Thiazoles; Thiazolidinediones; Troglitazone; Vasodilation; Vitamin E | 1998 |
Meloxicam inhibits the growth of colorectal cancer cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Collagen; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Drug Combinations; Humans; Isoenzymes; Laminin; Meloxicam; Membrane Proteins; Mice; Mice, Nude; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Thiazines; Thiazoles; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Gastric Mucosa; Humans; Hyperalgesia; Isoenzymes; Male; Membrane Proteins; Mice; Oxazoles; Phenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiazoles | 1999 |
Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinoprostone; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Interferon-gamma; Lipopolysaccharides; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin D2; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 1999 |
Lack of beneficial effect of COX-2 inhibitors in an experimental model of colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Male; Nitrobenzenes; Peroxidase; Peroxidases; Phenols; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazoles; Trinitrobenzenesulfonic Acid | 1999 |
Natriuretic response to increased pressure is preserved with COX-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Kidney; Male; Meloxicam; Natriuresis; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles | 1999 |
Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Gastric Mucosa; Gastrins; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Time Factors | 1999 |
Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arteriosclerosis; Aspirin; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indans; Indomethacin; Interleukin-1; Interleukin-8; Isoenzymes; Mammary Arteries; Meloxicam; Membrane Proteins; Muscle, Smooth, Vascular; Neutrophils; Prostaglandin-Endoperoxide Synthases; Saphenous Vein; Sulfonamides; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2000 |
Preferential inhibition of cyclooxygenase-2 by meloxicam in human rheumatoid synoviocytes.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blotting, Western; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Membrane; Thiazines; Thiazoles | 2000 |
Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Blood Platelets; Cyclic S-Oxides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Female; Gastric Mucosa; Humans; Interleukin-1; Isoenzymes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Structure-Activity Relationship; Synovial Membrane; Thiazoles | 2000 |
The role of cytokines and prostaglandin-E(2) in thymulin induced hyperalgesia.
Topics: Analgesics, Non-Narcotic; Animals; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Immune Sera; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Male; Meloxicam; Nerve Growth Factor; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Thiazines; Thiazoles; Thymic Factor, Circulating; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
Relationship between the ability to support differentiation of osteoclast-like cells and adipogenesis in murine stromal cells derived from bone marrow.
Topics: Adipocytes; Animals; Bone Marrow Cells; Carrier Proteins; Cell Culture Techniques; Cell Differentiation; Cell Line; Clone Cells; Coculture Techniques; Dinoprostone; Down-Regulation; Glycerophosphates; Male; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Osteoblasts; Osteoclasts; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Spleen; Stromal Cells; Thiazoles; Thiazolidinediones | 2000 |
In vitro effects of nonsteroidal anti-inflammatory drugs on cyclooxygenase activity in dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Carbazoles; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; DNA; DNA Primers; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Gene Expression Regulation, Enzymologic; Immunoenzyme Techniques; Isoenzymes; Ketoprofen; Lipopolysaccharides; Meloxicam; ortho-Aminobenzoates; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thiazines; Thiazoles | 2000 |
Discrimination between NK and LAK cytotoxic activities of murine spleen cells by MTT assay: differential inhibition by PGE(2) and EDTA.
Topics: Animals; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Dinoprostone; Edetic Acid; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; Spleen; Tetrazolium Salts; Thiazoles | 2000 |
Effects of meloxicam on oxygen radical generation in rat gastric mucosa.
Topics: Animals; Dinoprostone; Female; Free Radicals; Gastric Mucosa; Gastrointestinal Hemorrhage; Glutathione; Glutathione Peroxidase; Male; Meloxicam; Neutrophils; Peroxidase; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiazines; Thiazoles; Xanthine Oxidase | 2000 |
Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Escherichia coli; Flurbiprofen; Humans; Isoenzymes; Lipopolysaccharides; Meloxicam; Membrane Proteins; Monocytes; Ophthalmic Solutions; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam, an inhibitor of prostaglandin synthase-II.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenocorticotropic Hormone; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Female; Hydrocortisone; In Vitro Techniques; Isoenzymes; Labor, Induced; Meloxicam; Mifepristone; Pituitary-Adrenal System; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sheep; Thiazines; Thiazoles; Tocolytic Agents; Uterine Contraction | 2000 |
Meloxicam inhibits prostaglandin E(2) generation via cyclooxygenase 2 in the inflammatory site but not that via cyclooxygenase 1 in the stomach.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Juice; Isoenzymes; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Pleura; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach; Sulfonamides; Thiazines; Thiazoles | 2000 |
Pharmacological profile of YM-31636, a novel 5-HT3 receptor agonist, in vitro.
Topics: Acetylcholine; Action Potentials; Animals; Anthraquinones; Atrial Function; Biguanides; Binding, Competitive; Colon; Dinoprostone; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Humans; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Pyrroles; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Receptor Agonists; Thiazoles | 2000 |
The human prostanoid DP receptor stimulates mucin secretion in LS174T cells.
Topics: Benzoates; Binding, Competitive; Cell Membrane; Colon; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Hydantoins; In Situ Hybridization; Mucins; Prostaglandin D2; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Thiazoles; Thiazolidines; Transcription, Genetic; Tritium; Tumor Cells, Cultured | 2000 |
2,4-Disubstituted oxazoles and thiazoles as latent pharmacophores for diacylhydrazine of SC-51089, a potent PGE2 antagonist.
Topics: Dinoprostone; Hydrazines; Oxazepines; Oxazoles; Thiazoles | 2001 |
Effects of anti-inflammatory drugs on lipopolysaccharide-challenged and -unchallenged equine synovial explants.
Topics: Animals; Anti-Inflammatory Agents; Carbazoles; Clonixin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Horses; Hyaluronic Acid; Isoenzymes; Ketoprofen; Lipopolysaccharides; Meloxicam; Methylprednisolone; Organ Culture Techniques; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Synovial Membrane; Thiazines; Thiazoles | 2001 |
Thrombin-stimulated growth, clustering, and collagen lattice contraction of human gingival fibroblasts is associated with its protease activity.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Cell Aggregation; Cell Division; Cells, Cultured; Collagen; Coloring Agents; Crystallization; Cytochalasin B; Dinoprostone; Enzyme Activation; Fibroblasts; Gene Expression; Gingiva; Humans; Peptide Fragments; Receptor, PAR-1; Receptor, PAR-2; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction; Serine Proteinase Inhibitors; Serum Albumin, Bovine; Statistics as Topic; Tetrazolium Salts; Thiazoles; Thrombin; Time Factors; Trypsin | 2001 |
Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.
Topics: Arachidonic Acid; Arthritis, Rheumatoid; Chromans; Cyclooxygenase 2; Cysteine; Dinoprostone; Feedback; Humans; Isoenzymes; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Synovial Membrane; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Effects of steroidal and non-steroidal antiphlogistic drugs on eicosanoid synthesis in irritated skin: studies with the isolated perfused bovine udder.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cattle; Clobetasol; Clonixin; Culture Techniques; Dinoprostone; Disease Models, Animal; Eicosanoids; Female; Glucocorticoids; Indomethacin; Mammary Glands, Animal; Meloxicam; Skin Physiological Phenomena; Thiazines; Thiazoles | 2001 |
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrins; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2001 |
Regulation of PGE(2) and PGI(2) release from human umbilical vein endothelial cells by actin cytoskeleton.
Topics: Actins; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Cell Survival; Cells, Cultured; Colchicine; Cytochalasin D; Cytoskeleton; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Marine Toxins; Microtubules; Nocodazole; Thiazoles; Thiazolidines; Umbilical Veins | 2001 |
Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide.
Topics: Animals; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Gastrointestinal Agents; Injections, Intravenous; Intestinal Mucosa; Intestine, Large; Leukotriene B4; Lipopolysaccharides; Lipoxygenase Inhibitors; Male; Prednisolone; Pyridines; Rats; Rats, Inbred F344; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase; Time Factors | 2001 |
Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein.
Topics: Base Sequence; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Primers; Enzyme Induction; Humans; Immunohistochemistry; Isoenzymes; Lipoproteins, LDL; Membrane Proteins; Monocytes; Nitrobenzenes; Oxidation-Reduction; Phospholipids; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis.
Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Chronic Disease; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Isoenzymes; Membrane Proteins; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Thiazoles; Thromboxane B2 | 2002 |
The effects of a cytokine suppressive anti-inflammatory drug on the output of prostaglandin E(2) and interleukin-1 beta from human fetal membranes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Culture Techniques; Cyclooxygenase 2; Dinoprostone; Extraembryonic Membranes; Female; Gene Expression; Humans; Imidazoles; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Thiazoles | 2002 |
Effects of aminoguanidine and meloxicam on nitric oxide and prostaglandin E production induced by lipopolysaccharide in the hypothalamus and anterior pituitary of the rat.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endotoxemia; Guanidines; Hypothalamus; Inflammation; Isoenzymes; Lipopolysaccharides; Male; Meloxicam; Nitric Oxide; Nitric Oxide Synthase; Pituitary Gland, Anterior; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles; Time Factors; Up-Regulation | 2001 |
Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2.
Topics: Animals; Cell Culture Techniques; Cell Death; Chromans; Clofibrate; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Escherichia coli; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lipopolysaccharides; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisome Proliferators; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Effects of oxicam inhibitors of cyclooxygenase on oxidative stress generation in rat gastric mucosa. A comparative study.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Gastric Mucosa; Glutathione; Isoenzymes; Male; Meloxicam; Membrane Proteins; Oxidative Stress; Peroxidase; Piroxicam; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Superoxide Dismutase; Thiazines; Thiazoles; Xanthine Oxidase | 2002 |
Expression of peroxisome proliferator-activated receptors in human testicular cancer and growth inhibition by its agonists.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Chromans; Dinoprostone; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Immunohistochemistry; Ligands; Male; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Testicular Neoplasms; Testis; Thiazoles; Thiazolidinediones; Thiazolidines; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2002 |
In vitro enhancement of tumor cell radiosensitivity by a selective inhibitor of cyclooxygenase-2 enzyme: mechanistic considerations.
Topics: Animals; Apoptosis; Cell Cycle; Cell Survival; Coloring Agents; Cyclin A; Cyclin A1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Damage; Drug Screening Assays, Antitumor; In Situ Nick-End Labeling; Isoenzymes; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; RNA, Messenger; Sulfonamides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Modulation of cell recruitment by anti-inflammatory agents in antigen-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemokine CCL2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Gene Expression Regulation; Interleukin-8; Leukocytes; Meloxicam; Neutrophil Infiltration; Ovalbumin; Rabbits; Thiazines; Thiazoles | 2002 |
Effect of peroxisome proliferator-activated receptor gamma on thromboxane A(2) and prostaglandin E(2) production in macrophage cell lines.
Topics: Animals; Cell Line; Chromans; Dinoprostone; Humans; Ligands; Macrophages; Monocytes; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Thromboxane A2; Transcription Factors; Transfection; Troglitazone | 2002 |
Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line.
Topics: Active Transport, Cell Nucleus; Arachidonic Acid; Catalysis; Cell Nucleus; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytosol; Dinoprostone; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids; Green Fluorescent Proteins; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Intercellular Signaling Peptides and Proteins; Isoenzymes; Luminescent Proteins; Lymphokines; Male; MAP Kinase Signaling System; Meloxicam; Membrane Proteins; Nitrobenzenes; Phosphatidylinositol 3-Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Thiazines; Thiazoles; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
In vivo effects of meloxicam and aspirin on blood, gastric mucosal, and synovial fluid prostanoid synthesis in dogs.
Topics: Animals; Aspirin; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dog Diseases; Dogs; Gastric Mucosa; Isoenzymes; Male; Meloxicam; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Stifle; Synovial Fluid; Thiazines; Thiazoles; Thromboxane B2 | 2002 |
Inhibition of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by cyclooxygenase inhibitors and chemopreventive agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Hydroxyprostaglandin Dehydrogenases; Inhibitory Concentration 50; Isoenzymes; Kinetics; Membrane Proteins; NAD; Placenta; Prostaglandin-Endoperoxide Synthases; Thiazoles; Thiazolidinediones | 2002 |
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Lung; Membrane Proteins; Muscle, Smooth; NF-kappa B; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Response Elements; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 2003 |
Cyclooxygenase-2 inhibition and experimental colitis: beneficial effects of phosphorothioated antisense oligonucleotide and meloxicam.
Topics: Animals; Colitis; Colon; Cyclooxygenase Inhibitors; Dinoprostone; Male; Meloxicam; Oligonucleotides, Antisense; Peroxidase; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiazines; Thiazoles; Thromboxane B2; Tumor Necrosis Factor-alpha | 2002 |
In vitro evaluation of thiazolyl and benzothiazolyl Schiff bases on pig cartilage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Dinoprostone; Glycosaminoglycans; In Vitro Techniques; Interleukin-1; Nasal Septum; Nitric Oxide; Schiff Bases; Swine; Thiazoles | 2002 |
Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor.
Topics: Acetamides; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-2; Lymphocytes; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiosemicarbazones | 2003 |
Interaction among beta-endorphin, nitric oxide and prostaglandins during ovulation in rats.
Topics: Animals; beta-Endorphin; Blotting, Western; Chorionic Gonadotropin; Dinoprostone; Female; Indomethacin; Meloxicam; Models, Animal; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovary; Ovulation; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles | 2003 |
Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299.
Topics: Apoptosis; bcl-2-Associated X Protein; Bee Venoms; Caspases; Cell Cycle; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Fragmentation; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Genes, bcl-2; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Indoles; Isoenzymes; Lung Neoplasms; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2003 |
Synthesis and activities of oxidative metabolites of the anti-arthritic drug candidate S-2474.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Cyclic S-Oxides; Dinoprostone; Edema; Humans; Interleukin-1; Leukotriene B4; Lipoxygenase Inhibitors; Microsomes, Liver; Rats; Thiazoles | 2003 |
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Extraembryonic Membranes; Female; Furans; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Meloxicam; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles | 2003 |
Mucosal damage induced by preferential COX-1 and COX-2 inhibitors: role of prostaglandins and inflammatory response.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Hydrochloric Acid; Male; Meloxicam; Peroxidase; Piroxicam; Rats; Rats, Wistar; Stomach Ulcer; Thiazines; Thiazoles | 2004 |
3-OH flavone inhibition of epidermal growth factor-induced proliferaton through blocking prostaglandin E2 production.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cell Division; Colony-Forming Units Assay; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Effects of dexamethasone and sulfasalazine on prostaglandin E2 output by human placental cells in vitro.
Topics: Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Hydrocortisone; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Meloxicam; Placenta; Pregnancy; Sheep; Sulfasalazine; Thiazines; Thiazoles | 2004 |
The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.
Topics: Calcium; Cell Differentiation; Cell Division; Colforsin; Complement C5a; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Humans; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptors, Histamine H2; Receptors, Prostaglandin E; Recombinant Proteins; Signal Transduction; Thiazoles; Time Factors; U937 Cells | 2004 |
Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia.
Topics: Animals; Animals, Newborn; Blotting, Western; Brain; Catalase; Catecholamines; Cell Count; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Female; Fluoresceins; Imidazolines; Intracellular Space; Isoenzymes; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organometallic Compounds; Pregnancy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Superoxide Dismutase; Tetrazolium Salts; Thiazoles | 2004 |
Effects of aminoguanidine and cyclooxygenase inhibitors on nitric oxide and prostaglandin production, and nitric oxide synthase and cyclooxygenase expression induced by lipopolysaccharide in the estrogenized rat uterus.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Embryo Loss; Estrogens; Female; Guanidines; Indomethacin; Inflammation; Isoenzymes; Lipopolysaccharides; Meloxicam; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Thiazines; Thiazoles; Uterus | 2004 |
Impact of the cyclooxygenase system on doxorubicin-induced functional multidrug resistance 1 overexpression and doxorubicin sensitivity in acute myeloid leukemic HL-60 cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rhodamine 123; Thiazines; Thiazoles | 2005 |
Nitric oxide and prostaglandin E2 synthesis inhibitory activities of diarylheptanoids from the barks of Alnus japonica steudel.
Topics: Alnus; Chromatography, Thin Layer; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diarylheptanoids; Dinoprostone; Interferon-gamma; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Nitric Oxide; Nitric Oxide Synthase; Plant Bark; Prostaglandin-Endoperoxide Synthases; Spectrophotometry, Infrared; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles | 2005 |
Scoparone from Artemisia capillaris inhibits the release of inflammatory mediators in RAW 264.7 cells upon stimulation cells by interferon-gamma Plus LPS.
Topics: Animals; Anti-Inflammatory Agents; Artemisia; Blotting, Western; Cell Line; Cell Survival; Coumarins; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Stimulation, Chemical; Tetrazolium Salts; Thiazoles | 2005 |
COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Horses; In Vitro Techniques; Male; Meloxicam; Phenylbutazone; Thiazines; Thiazoles; Thromboxane B2 | 2005 |
Inducible cyclooxygenase released prostaglandin mediates immunosuppression in acute phase of experimental Trypanosoma cruzi infection.
Topics: Acute Disease; Animals; Cells, Cultured; Chagas Disease; Concanavalin A; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Immune Tolerance; Lymphocyte Activation; Male; Meloxicam; Mice; Mice, Inbred BALB C; Parasitemia; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate; Spleen; T-Lymphocytes; Thiazines; Thiazoles | 2005 |
Activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) increases the expression of prostaglandin E2 receptor subtype EP4. The roles of phosphatidylinositol 3-kinase and CCAAT/enhancer-binding protein beta.
Topics: Androstadienes; Carcinoma; CCAAT-Binding Factor; Cell Line, Tumor; Cell Proliferation; Dinoprostone; Dose-Response Relationship, Drug; Enhancer Elements, Genetic; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; Mutation; Oligonucleotides, Antisense; Phosphatidylinositol 3-Kinases; PPAR delta; PPAR-beta; Promoter Regions, Genetic; Receptors, Prostaglandin; RNA, Messenger; RNA, Small Interfering; Thiazoles; Transcription, Genetic; Wortmannin | 2005 |
Isolation of saponins with the inhibitory effect on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha production from Pleurospermum kamtschaticum.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apiaceae; Cell Line; Cell Survival; Dinoprostone; Humans; Lipopolysaccharides; Macrophages; Nitric Oxide; Plant Extracts; Prostaglandin Antagonists; Sapogenins; Saponins; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
Meloxicam inhibits osteosarcoma growth, invasiveness and metastasis by COX-2-dependent and independent routes.
Topics: Apoptosis; Blotting, Western; Bone Neoplasms; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Profiling; Humans; Meloxicam; Osteosarcoma; Reverse Transcriptase Polymerase Chain Reaction; Thiazines; Thiazoles; Tumor Cells, Cultured | 2006 |
Suppression of inducible nitric oxide synthase and cyclooxygenase-2 expression in RAW 264.7 macrophages by sesquiterpene lactones.
Topics: Animals; Anti-Inflammatory Agents; Asteraceae; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Mitochondria; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Nitrites; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane; Tetrazolium Salts; Thiazoles | 2005 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
The cyclin-dependent kinase 2 inhibitor down-regulates interleukin-1beta-mediated induction of cyclooxygenase-2 expression in human lung carcinoma cells.
Topics: Carcinoma, Non-Small-Cell Lung; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cyclin-Dependent Kinase 2; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; Lung Neoplasms; Oxazoles; Promoter Regions, Genetic; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thiazoles; Transcription, Genetic; Transfection | 2006 |
Prostaglandins modulate nitric oxide synthase activity early in time in the uterus of estrogenized rat challenged with lipopolysaccharide.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Estrogens; Female; Lipopolysaccharides; Meloxicam; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Thiazines; Thiazoles; Time Factors; Uterus | 2006 |
Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide.
Topics: Analysis of Variance; Animals; Cell Communication; Cell Death; Cell Line; Cell Survival; Coculture Techniques; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Hypothermia; Immunohistochemistry; Interferon-gamma; Isothiuronium; Lipopolysaccharides; Mice; Microglia; Neuroblastoma; Neurons; Nitric Oxide; Radioimmunoassay; Tetrazolium Salts; Thiazoles | 2006 |
Modulatory role of cyclooxygenase-2 in cerebrovascular coupling.
Topics: Animals; Blood Flow Velocity; Cerebrovascular Circulation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Forelimb; Magnetic Resonance Imaging; Male; Meloxicam; Oxygen; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles | 2006 |
Preventive effect of Ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kappaB in RAW 264.7 cells.
Topics: Animals; Blotting, Western; Cell Line; Cell Survival; Cyclooxygenase 2 Inhibitors; Dinoprostone; Electrophoretic Mobility Shift Assay; Ginkgo biloba; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2006 |
A novel positive feedback loop between peroxisome proliferator-activated receptor-delta and prostaglandin E2 signaling pathways for human cholangiocarcinoma cell growth.
Topics: Bile Duct Neoplasms; Blotting, Western; Cell Division; Cholangiocarcinoma; Cyclooxygenase 2; Dinoprostone; Group IV Phospholipases A2; Humans; Immunoprecipitation; Luciferases; Membrane Proteins; Phospholipases A; Phosphorylation; PPAR delta; Protein Binding; Receptors, Prostaglandin E; Recombinant Proteins; Response Elements; Signal Transduction; Thiazoles; Thymidine; Transcriptional Activation; Tumor Cells, Cultured | 2006 |
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytoprotection; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; Ibuprofen; Irritants; Male; Meloxicam; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles | 2007 |
Amygdalin suppresses lipopolysaccharide-induced expressions of cyclooxygenase-2 and inducible nitric oxide synthase in mouse BV2 microglial cells.
Topics: Amygdalin; Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Gene Expression Regulation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles | 2007 |
The anti-cancer effect of COX-2 inhibitors on gastric cancer cells.
Topics: Adenocarcinoma; Apoptosis; Celecoxib; Cell Cycle; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Microscopy, Fluorescence; Pyrazoles; Stomach Neoplasms; Sulfonamides; Tetrazolium Salts; Thiazoles | 2007 |
Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase.
Topics: Analysis of Variance; Cell Line; Culture Media, Conditioned; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Insecticides; Monocytes; Neuroblastoma; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Rotenone; Tetrazolium Salts; Thiazoles; Up-Regulation | 2007 |
Inhibitory effect of meloxicam, a selective cyclooxygenase-2 inhibitor, and ciglitazone, a peroxisome proliferator-activated receptor gamma ligand, on the growth of human ovarian cancers.
Topics: Animals; Apoptosis; Ascites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Immunohistochemistry; Intramolecular Oxidoreductases; Meloxicam; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Peritoneal Neoplasms; PPAR gamma; Prostaglandin-E Synthases; Survival Analysis; Thiazines; Thiazoles; Thiazolidinediones; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2007 |
A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata.
Topics: Animals; Cell Survival; Dinoprostone; Flavanones; Fruit; Glycosides; Interleukin-6; Lipopolysaccharides; Macrophages; Magnetic Resonance Spectroscopy; Mice; Poncirus; Prostaglandin Antagonists; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tetrazolium Salts; Thiazoles | 2007 |
In vivo and in vitro anti-inflammatory activities of alpha-linolenic acid isolated from Actinidia polygama fruits.
Topics: Acetic Acid; Actinidia; alpha-Linolenic Acid; Aminolevulinic Acid; Animals; Anti-Inflammatory Agents; Blotting, Western; Capillary Permeability; Carrageenan; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Edema; Enzyme Inhibitors; Fruit; Hexanes; Indicators and Reagents; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Solvents; Tetrazolium Salts; Thiazoles | 2007 |
Effects of an ophthalmic formulation of meloxicam on COX-2 expression, PGE2 release, and cytokine expression in a model of acute ocular inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Cornea; Croton Oil; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Endophthalmitis; Male; Meloxicam; Ophthalmic Solutions; Rabbits; RNA, Messenger; Thiazines; Thiazoles | 2008 |
Anti-inflammatory effect of honokiol is mediated by PI3K/Akt pathway suppression.
Topics: Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Cell Proliferation; Dinoprostone; Fibronectins; Humans; Lignans; Lipopolysaccharides; Lymphocytes; Mitogens; Nitric Oxide; Oncogene Protein v-akt; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2008 |
Trypanosoma cruzi: the role of PGE2 in immune response during the acute phase of experimental infection.
Topics: Acute Disease; Animals; Cells, Cultured; Chagas Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Etoricoxib; Fibrosis; Male; Meloxicam; Mice; Mice, Inbred BALB C; Myocardium; Parasitemia; Prostaglandins; Pyridines; Spleen; Sulfones; Thiazines; Thiazoles; Trypanosoma cruzi | 2008 |
Pharmacokinetics and pharmacodynamics of meloxicam in piglets.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Dinoprostone; Female; Half-Life; Male; Meloxicam; Metabolic Clearance Rate; Swine; Thiazines; Thiazoles; Thromboxane A2 | 2008 |
Preventive effects of a Kampo medicine, Shosaikoto, on inflammatory responses in LPS-treated human gingival fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gingiva; Gingivitis; Humans; Indicators and Reagents; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages; Medicine, Kampo; Monocytes; Porphyromonas gingivalis; Tetrazolium Salts; Thiazoles | 2008 |
Chemoprevention of glandular stomach carcinogenesis through duodenogastric reflux in rats by a COX-2 inhibitor.
Topics: Animals; Base Sequence; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; DNA Primers; Duodenogastric Reflux; Gastric Mucosa; Immunohistochemistry; Male; Meloxicam; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Thiazines; Thiazoles | 2008 |
A selective cyclooxygenase-2 inhibitor prevents inflammation-related squamous cell carcinogenesis of the forestomach via duodenogastric reflux in rats.
Topics: Animals; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Duodenogastric Reflux; Immunohistochemistry; Inflammation; Male; Meloxicam; Random Allocation; Rats; Rats, Inbred F344; Stomach Neoplasms; Thiazines; Thiazoles | 2009 |
Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells.
Topics: Animals; Cell Line, Tumor; Chemokine CCL2; Cyclooxygenase 2; Dinoprostone; Endothelial Cells; Enzyme Activation; Epithelial Cells; Gene Expression Regulation; Gene Silencing; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Mice; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Receptor, PAR-1; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thiazoles; Thrombin | 2009 |
The skin compatibility of distilled tall oils: evaluation with the bovine udder skin in vitro model system.
Topics: Animal Testing Alternatives; Animals; Cattle; Cell Survival; Dinoprostone; Female; Irritants; Mammary Glands, Animal; Models, Animal; Oils; Skin; Skin Irritancy Tests; Tetrazolium Salts; Thiazoles; Tissue Culture Techniques | 2009 |
PPARbeta/delta agonist increases the expression of PGE2 receptor subtype EP4 in human lung carcinoma cells.
Topics: Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dinoprostone; Electrophoretic Mobility Shift Assay; Humans; Lung Neoplasms; PPAR delta; PPAR-beta; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Thiazoles | 2009 |
Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.
Topics: Anemarrhena; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Interleukin-6; Lipopolysaccharides; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Plant Roots; Reverse Transcriptase Polymerase Chain Reaction; RNA; Saponins; Signal Transduction; Tetrazolium Salts; Thiazoles; Triterpenes; Tumor Necrosis Factor-alpha | 2009 |
[Changes in nitric oxide, prostaglandins and myeloperoxidase activity in acrolein-induced cystitis in rats].
Topics: Acrolein; Androstanes; Animals; Benzimidazoles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Dinoprostone; Drug Evaluation, Preclinical; Lactones; Male; Meloxicam; Membrane Proteins; Neurokinin-1 Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfones; Thiazines; Thiazoles; Urinary Bladder | 2009 |
Paeoniflorin protects RAW 264.7 macrophages from LPS-induced cytotoxicity and genotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Cell Line; Cell Survival; Comet Assay; Dinoprostone; DNA Breaks; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Glucosides; Lipopolysaccharides; Macrophages; Mice; Monoterpenes; Nitric Oxide; Tetrazolium Salts; Thiazoles | 2009 |
Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Dinoprostone; Disease Models, Animal; Female; Keratinocytes; Keratins; Keratoacanthoma; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; PPAR delta; PPAR-beta; RNA, Messenger; Skin Neoplasms; Sulfonamides; Thiazoles; Time Factors | 2010 |
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Etodolac; Isoenzymes; Ketoprofen; Kinetics; Lipopolysaccharides; Meloxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles; Thromboxane B2 | 2010 |
Enhanced protection by melatonin and meloxicam combination in experimental infection by Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Dinoprostone; Drug Synergism; Immunologic Factors; Interferon-gamma; Interleukin-2; Macrophages; Male; Melatonin; Meloxicam; Nitric Oxide; Rats; Rats, Wistar; Thiazines; Thiazoles; Trypanosoma cruzi | 2010 |
Water-retentive and anti-inflammatory properties of organic and inorganic substances from Korean sea mud.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Balneology; Body Water; Cell Line; Cell Survival; Coloring Agents; Dinoprostone; Geologic Sediments; Humans; Humic Substances; Inorganic Chemicals; Korea; Mass Spectrometry; Organic Chemicals; Radiation-Protective Agents; Skin; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2010 |
Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Chemokine CXCL2; Dinoprostone; Injections, Intravenous; Interleukin-6; Leukocytes; Lower Extremity; Male; Malondialdehyde; Models, Animal; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazoles | 2011 |
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles | 2010 |
Effects of firocoxib, meloxicam, and tepoxalin administration on eicosanoid production in target tissues of healthy cats.
Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Duodenum; Eicosanoids; Gastric Mucosa; Intestinal Mucosa; Kinetics; Leukotriene B4; Male; Meloxicam; Orchiectomy; Pyrazoles; Reference Values; Sulfones; Thiazines; Thiazoles | 2010 |
Dual effect of nitric oxide on uterine prostaglandin synthesis in a murine model of preterm labour.
Topics: Animals; Blotting, Western; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Female; Guanidines; Inflammation; Lipopolysaccharides; Meloxicam; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase; Obstetric Labor, Premature; Pregnancy; Radioimmunoassay; Thiazines; Thiazoles; Uterus | 2010 |
Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.
Topics: Adult; Aspirin; Cell Proliferation; Collagen; Dinoprostone; Electromagnetic Fields; Enzyme Inhibitors; Female; Humans; Intervertebral Disc; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Tetrazolium Salts; Thiazoles | 2010 |
Immunoregulatory function of bone marrow mesenchymal stem cells in EAE depends on their differentiation state and secretion of PGE2.
Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunomodulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Meloxicam; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Thiazines; Thiazoles | 2011 |
PDE4 inhibitor suppresses PGE2-induced osteoclast formation via COX-2-mediated p27(KIP1) expression in RAW264.7 cells.
Topics: Animals; Blotting, Western; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Dinoprostone; Flow Cytometry; Indicators and Reagents; Macrophages; Mice; Osteoclasts; Phosphodiesterase 4 Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles | 2011 |
Prostaglandin E2 receptor 1 activity regulates cell survival following hypoxia in cultured rat cortical neurons.
Topics: Analysis of Variance; Animals; Annexin A5; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclin D1; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Hydrazines; Hypoxia; Neurons; Oxazepines; Oxygen; Rats; Rats, Wistar; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2012 |
Effect of triethylene glycol dimethacrylate on the cytotoxicity, cyclooxygenase-2 expression and prostanoids production in human dental pulp cells.
Topics: Annexin A5; Apoptosis; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Culture Techniques; Cell Cycle; Cell Death; Cell Proliferation; Cell Shape; Coloring Agents; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclooxygenase 2; Dental Materials; Dental Pulp; Dinoprost; Dinoprostone; Enzyme Inhibitors; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Necrosis; Polyethylene Glycols; Polymethacrylic Acids; Propidium; Prostaglandins; Tetrazolium Salts; Thiazoles; Time Factors | 2012 |
Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE2 production in cells.
Topics: Cell Line; Dinoprostone; Humans; Inhibitory Concentration 50; Thiazoles | 2012 |
Meloxicam modulates oxidative stress status, inhibits prostaglandin E2, and abrogates apoptosis in carbon tetrachloride-induced rat hepatic injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbon Tetrachloride; Caspase 3; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Dinoprostone; Glutathione; Male; Malondialdehyde; Meloxicam; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles | 2012 |
Ultraviolet A regulates the stemness of human adipose tissue-derived mesenchymal stem cells through downregulation of the HIF-1α via activation of PGE(2)-cAMP signaling.
Topics: Adipose Tissue; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Culture Media, Serum-Free; Cyclic AMP; Cysteine; Dinoprostone; Down-Regulation; Gene Expression Regulation; Homeodomain Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Nanog Homeobox Protein; NF-kappa B; Octamer Transcription Factor-3; Radiation-Protective Agents; RNA, Messenger; Signal Transduction; SOXB1 Transcription Factors; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 2012 |
Adverse effects of bilateral lower limb ischemia-reperfusion on inducing kidney injuries in rats could be ameliorated by platonin.
Topics: Animals; Blood Pressure; Dinoprostone; Heart Rate; Kidney; Lower Extremity; Male; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiazoles | 2012 |
Pin1 is required for ultraviolet A-stimulated cyclooxygenase-2 induction in mouse epidermal cells.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; Epidermis; Epithelial Cells; Meloxicam; Mice; Naphthoquinones; NF-kappa B; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Signal Transduction; Thiazines; Thiazoles; Transcription Factor AP-1; Ultraviolet Rays | 2013 |
A study to compare circulating flunixin, meloxicam and gabapentin concentrations with prostaglandin E₂ levels in calves undergoing dehorning.
Topics: Amines; Analgesics; Animals; Area Under Curve; Cattle; Clonixin; Cyclohexanecarboxylic Acids; Dinoprostone; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Horns; Male; Meloxicam; Pain; Random Allocation; Statistics, Nonparametric; Thiazines; Thiazoles | 2013 |
Inhibition of microsomal prostaglandin E synthase-1 by aminothiazoles decreases prostaglandin E2 synthesis in vitro and ameliorates experimental periodontitis in vivo.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Humans; Intramolecular Oxidoreductases; Microsomes; Periodontitis; Prostaglandin Antagonists; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Thiazoles | 2013 |
Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylamines; Cell Count; Cell Movement; Cells, Cultured; Cyclams; Dinoprostone; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Heterocyclic Compounds; Humans; Meloxicam; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteopontin; Papio; Receptors, Prostaglandin E, EP4 Subtype; Stem Cells; Thiazines; Thiazoles | 2013 |
Stimulatory effects of glucose and Porphyromonas gingivalis lipopolysaccharide on the secretion of inflammatory mediators from human macrophages.
Topics: Calcium; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chelating Agents; Coloring Agents; Dinoprostone; Egtazic Acid; Glucose; Humans; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Mitochondria; Oxidoreductases; Porphyromonas gingivalis; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
The effect of timing of oral meloxicam administration on physiological responses in calves after cautery dehorning with local anesthesia.
Topics: Administration, Oral; Anesthesia, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Dairying; Dinoprostone; Haptoglobins; Horns; Hydrocortisone; Male; Meloxicam; Pain Measurement; Substance P; Thiazines; Thiazoles | 2013 |
Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor.
Topics: Animals; Cisplatin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Gene Expression Regulation, Enzymologic; Kidney; Macrophages; Male; Meloxicam; Mice; Mice, Inbred BALB C; Oxidative Stress; Thiazines; Thiazoles; Thromboxane B2 | 2013 |
Effects of chitosan particles in periodontal pathogens and gingival fibroblasts.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Anthracenes; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacteriological Techniques; Cell Survival; Cells, Cultured; Chitosan; Dinoprostone; Fibroblasts; Gingiva; Humans; Indicators and Reagents; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Nanoparticles; NF-kappa B; Periodontal Diseases; Phosphorylation; Porphyromonas gingivalis; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor RelA | 2013 |
Compensatory cellular reactions to nonsteroidal anti-inflammatory drugs on osteogenic differentiation in canine bone marrow-derived mesenchymal stem cells.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carbazoles; Cell Differentiation; Dinoprostone; Diphenylamine; DNA Primers; Dogs; Gene Expression Profiling; Gene Expression Regulation; Genetic Markers; Immunoassay; Indomethacin; Interleukin-1beta; Meloxicam; Mesenchymal Stem Cells; Osteocalcin; Osteogenesis; Phenylacetates; Statistics, Nonparametric; Thiazines; Thiazoles | 2014 |
2-Cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride inhibits microglial activation by suppression of nuclear factor-kappa B and mitogen-activated protein kinase signaling.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Interleukin-1beta; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; Mitogen-Activated Protein Kinase 1; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Thiazoles; Toll-Like Receptor 4; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Modulator effects of meloxicam against doxorubicin-induced nephrotoxicity in mice.
Topics: Animals; Caspase 3; Dinoprostone; Doxorubicin; Humans; Interleukin-6; Lipid Peroxidation; Male; Meloxicam; Mice; Neoplasms; Oxidative Stress; Renal Insufficiency; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
Juvenile ovary to testis transition in zebrafish involves inhibition of ptges.
Topics: Animals; beta Catenin; Cyclooxygenase Inhibitors; Dinoprostone; Embryo, Nonmammalian; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Intramolecular Oxidoreductases; Male; Meloxicam; Ovary; Prostaglandin D2; Prostaglandin-E Synthases; Sex Determination Processes; Sex Ratio; Signal Transduction; SOX9 Transcription Factor; Testis; Thiazines; Thiazoles; Zebrafish; Zebrafish Proteins | 2014 |
Evaluation of the reproductive toxicity of naproxen sodium and meloxicam in male rats.
Topics: Alprostadil; Animals; Catalase; Cyclooxygenase Inhibitors; Dinoprostone; Follicle Stimulating Hormone; Glutathione; Glutathione Peroxidase; Luteinizing Hormone; Male; Meloxicam; Naproxen; Rats, Wistar; Sperm Count; Sperm Motility; Superoxide Dismutase; Testis; Testosterone; Thiazines; Thiazoles | 2015 |
Modulatory effects of meloxicam on cardiotoxicity and antitumor activity of doxorubicin in mice.
Topics: Animals; Antibiotics, Antineoplastic; Caspase 3; Catalase; Cyclooxygenase 2 Inhibitors; Dinoprostone; Doxorubicin; Female; Glutathione; Glutathione Peroxidase; Heart Diseases; L-Lactate Dehydrogenase; Lipid Peroxidation; Mammary Neoplasms, Experimental; Meloxicam; Mice; Myocardium; Organ Size; Superoxide Dismutase; Thiazines; Thiazoles | 2014 |
Inhibition of group IVA cytosolic phospholipase A2 by thiazolyl ketones in vitro, ex vivo, and in vivo.
Topics: Animals; Arachidonic Acid; Arthritis; Blood Proteins; Cell Line, Tumor; Collagen; Cytosol; Dinoprostone; Drug Design; Group IV Phospholipases A2; Humans; Ketones; Male; Mice; Oleic Acid; Synovial Membrane; Thiazoles | 2014 |
Impact of transmammary-delivered meloxicam on biomarkers of pain and distress in piglets after castration and tail docking.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Castration; Dinoprostone; Meloxicam; Pain, Postoperative; Swine; Thiazines; Thiazoles | 2014 |
The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.
Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Lipopolysaccharides; Meloxicam; Mice; Mice, Knockout; Prostaglandin D2; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sleep; Thiazines; Thiazoles | 2015 |
Thiazole derivatives as inhibitors of cyclooxygenases in vitro and in vivo.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; HEK293 Cells; Humans; Mice; Molecular Docking Simulation; Platelet Aggregation; Protein Conformation; RAW 264.7 Cells; Thiazoles | 2015 |
Reduction of spinal PGE2 concentrations prevents swim stress-induced thermal hyperalgesia.
Topics: Animals; Biomarkers; Corticosterone; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Escape Reaction; Hot Temperature; Hyperalgesia; Ketoprofen; Male; Meloxicam; Rats, Sprague-Dawley; Spinal Cord; Stress, Psychological; Swimming; Thiazines; Thiazoles | 2015 |
Protective effects of rosuvastatin in a rat model of lung contusion: Stimulation of the cyclooxygenase 2-prostaglandin E-2 pathway.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Contusions; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung; Male; Meloxicam; Pyrimidines; Random Allocation; Rats; Rosuvastatin Calcium; Sulfonamides; Thiazines; Thiazoles | 2015 |
Protease-activated receptor 2 activation is sufficient to induce the transition to a chronic pain state.
Topics: Animals; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Butadienes; Chronic Pain; Dinoprostone; Disease Models, Animal; Facial Expression; Hydrazones; Hyperalgesia; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Nitriles; Protein Kinase C; Receptor, PAR-2; Receptor, trkB; Signal Transduction; Thiazoles | 2015 |
Intracellular EP2 prostanoid receptor promotes cancer-related phenotypes in PC3 cells.
Topics: Analysis of Variance; Blotting, Western; Bromodeoxyuridine; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dinoprostone; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Microscopy, Fluorescence; Neovascularization, Pathologic; Phenotype; Prostatic Neoplasms; Receptors, Prostaglandin E, EP2 Subtype; Signal Transduction; Tetrazolium Salts; Thiazoles | 2015 |
DFL23448, A Novel Transient Receptor Potential Melastin 8-Selective Ion Channel Antagonist, Modifies Bladder Function and Reduces Bladder Overactivity in Awake Rats.
Topics: Animals; Behavior, Animal; Cold Temperature; Dinoprostone; Female; Half-Life; HEK293 Cells; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Tetrazoles; Thiazoles; TRPM Cation Channels; Urinary Bladder; Urinary Bladder, Overactive; Urination; Urodynamics | 2016 |
DF2755A, a novel non-competitive allosteric inhibitor of CXCR1/2, reduces inflammatory and post-operative pain.
Topics: Adult; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cell Line, Tumor; Cell Movement; Cells, Cultured; Chemokine CXCL1; Dinoprostone; Guinea Pigs; Humans; Hyperalgesia; Interleukin-8; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Pain, Postoperative; Phenylacetates; Physical Stimulation; Rabbits; Rats; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Thiazoles | 2016 |
Aminothiazoles inhibit RANKL- and LPS-mediated osteoclastogenesis and PGE2 production in RAW 264.7 cells.
Topics: Actins; Animals; Cathepsin K; Cell Count; Cell Differentiation; Dinoprostone; Humans; Lipopolysaccharides; Macrophages; Mice; Osteoclasts; Osteogenesis; Osteoprotegerin; Prostaglandin-E Synthases; RANK Ligand; RAW 264.7 Cells; RNA, Messenger; Tartrate-Resistant Acid Phosphatase; Thiazoles; Tumor Necrosis Factor-alpha | 2016 |
Meloxicam suppresses hepatocellular carcinoma cell proliferation and migration by targeting COX-2/PGE2-regulated activation of the β-catenin signaling pathway.
Topics: Antigens, CD; beta Catenin; Cadherins; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Meloxicam; Neoplasm Invasiveness; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfonamides; Thiazines; Thiazoles | 2016 |
Cyclooxygenase-2 Signalling Pathway in the Cortex is Involved in the Pathophysiological Mechanisms in the Rat Model of Depression.
Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Depression; Dinoprostone; Disease Models, Animal; Gene Expression Regulation; Male; Meloxicam; Rats; RNA Interference; Signal Transduction; Superoxide Dismutase; Thiazines; Thiazoles | 2017 |
The protection of meloxicam against chronic aluminium overload-induced liver injury in rats.
Topics: Aluminum; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Cytokines; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation; Inflammation Mediators; Liver; Male; Malondialdehyde; Meloxicam; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Thiazines; Thiazoles | 2017 |
Platonin mitigates vascular hyporeactivity of thoracic aorta in septic rats.
Topics: Animals; Aorta, Thoracic; Cyclooxygenase 2; Dinoprostone; Drug Evaluation, Preclinical; Male; Random Allocation; Rats, Sprague-Dawley; Sepsis; Thiazoles; Vasoconstriction | 2018 |
Cyclooxygenase inhibitors potentiate receptor tyrosine kinase therapies in bladder cancer cells in vitro.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Axitinib; Benzamides; Caspases; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imidazoles; Indazoles; Indomethacin; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Pyridines; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thiazoles; Urinary Bladder Neoplasms | 2018 |
Aminothiazoles inhibit osteoclastogenesis and PGE
Topics: Animals; Bone Resorption; Cell Differentiation; Cell Line; Coculture Techniques; Dinoprostone; Inflammation; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Osteoblasts; Osteoclasts; Osteogenesis; Osteoprotegerin; Periodontal Ligament; Prostaglandin-E Synthases; RANK Ligand; RAW 264.7 Cells; Tartrate-Resistant Acid Phosphatase; Thiazoles | 2019 |
Anti-Inflammatory and Antioxidant Effects of
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asteraceae; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Proteins; Methanol; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; RAW 264.7 Cells; Reactive Oxygen Species; Sepsis; Tetrazolium Salts; Thiazoles | 2020 |
Measurement of Cyclooxygenase Products in Plasma as Markers for Inhibition of Cyclooxygenase Isoforms by Oral Meloxicam in New Zealand White Rabbits (
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cat Diseases; Cats; Cyclooxygenase 2; Dinoprostone; Dog Diseases; Dogs; Meloxicam; Pain; Protein Isoforms; Rabbits; Thiazines; Thiazoles | 2023 |