thiazoles has been researched along with desoxyepothilone a in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balog, A; Danishefsky, SJ; Kohl, NE; Moasser, MM; Oliff, A; Rosen, N; Sepp-Lorenzino, L; Su, DS | 1 |
| Altmann, KH; O'Reilly, T; Wartmann, M | 1 |
| Lerner, RA; Miller, GP; Sinha, SC; Sun, J; Wartmann, M | 1 |
| Gerth, K; Hardt, IH; Höfle, G; Reichenbach, H; Sasse, F; Steinmetz, H | 1 |
| Hertweck, C | 1 |
| Lerner, RA; Sinha, SC; Sun, J; Wartmann, M | 1 |
| Chen, H; O'Connor, SE; Walsh, CT | 1 |
| Carney, JR; Kennedy, J; Liu, Y; Mutka, SC | 1 |
2 review(s) available for thiazoles and desoxyepothilone a
| Article | Year |
|---|---|
Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line; Cell Membrane Permeability; Drug Resistance, Multiple; Drug Tolerance; Epothilones; Epoxy Compounds; Humans; Lactones; Microtubules; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Thiazoles; Tubulin; Tumor Cells, Cultured | 2000 |
The multiplasmid approach: a new perspective for combinatorial biosynthesis.
Topics: Acyl Coenzyme A; Antineoplastic Agents; Bacterial Proteins; Carrier Proteins; Combinatorial Chemistry Techniques; Epothilones; Epoxy Compounds; Genes, Bacterial; Lactones; Macrolides; Molecular Structure; Multienzyme Complexes; Open Reading Frames; Plasmids; Thiazoles | 2000 |
6 other study(ies) available for thiazoles and desoxyepothilone a
| Article | Year |
|---|---|
Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones.
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Apoptosis; Cell Cycle; DNA Fragmentation; Drug Synergism; Enzyme Inhibitors; Epothilones; Farnesyltranstransferase; Humans; Methionine; Mitosis; Paclitaxel; Thiazoles; Tumor Cells, Cultured | 1998 |
Catalytic antibody route to the naturally occurring epothilones: total synthesis of epothilones A-F.
Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antibodies, Catalytic; Antineoplastic Agents; Epothilones; Epoxy Compounds; Fructose-Bisphosphate Aldolase; Haptens; Macrolides; Magnetic Resonance Spectroscopy; Molecular Structure; Myxococcales; Stereoisomerism; Thiazoles | 2001 |
New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies.
Topics: Animals; Antineoplastic Agents; Cell Line; Chromatography, High Pressure Liquid; Epothilones; Epoxy Compounds; Fibroblasts; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; Myxococcales; Structure-Activity Relationship; Thiazoles | 2001 |
Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of C-13 alkylation of epothilones.
Topics: Aldehyde-Lyases; Alkylation; Animals; Antibodies; Antineoplastic Agents; Catalysis; Epothilones; Humans; Lactones; Macrolides; Magnetic Resonance Spectroscopy; Molecular Conformation; Stereoisomerism; Swine; Thiazoles; Tubulin; Tumor Cells, Cultured | 2001 |
Enzymatic assembly of epothilones: the EpoC subunit and reconstitution of the EpoA-ACP/B/C polyketide and nonribosomal peptide interfaces.
Topics: Acrylates; Acyl Carrier Protein; Acyltransferases; Alcohol Oxidoreductases; Antineoplastic Agents; Bacterial Proteins; Epothilones; Escherichia coli; Hydro-Lyases; Macrolides; Multienzyme Complexes; Peptide Synthases; Protein Structure, Tertiary; Proteins; Thiazoles | 2002 |
Heterologous production of epothilone C and D in Escherichia coli.
Topics: Catalysis; Cysteamine; Epothilones; Escherichia coli; Methacrylates; Peptide Chain Elongation, Translational; Peptide Synthases; Polyketide Synthases; Thiazoles | 2006 |