thiazoles has been researched along with dacarbazine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (61.11) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Barvaux, VA; Gillum, AM; Lorigan, P; Margison, GP; McElhinney, RS; McMurry, TB; Ranson, M | 1 |
| Cairncross, JG; Mymryk, JS; Xu, GW | 1 |
| Benjamin, RS; Patel, SR | 1 |
| Fujiwara, Y; Gega, M; Gondo, N; Hashimoto-Tamaoki, T; Ikeuchi, H; Noda, M; Oshima, T; Tamura, K; Tsukamoto, K; Utsunomiya, J; Yamamura, T; Yanagi, H; Yoshikawa, R | 1 |
| Baia, GS; Dinca, EB; James, CD; Kimura, ET; Lal, A; McDermott, MW; Ozawa, T; VandenBerg, SR | 1 |
| Cambar, J; De Giorgi, F; Ichas, F; L'Azou, B; Passagne, I; Pédeboscq, S; Pometan, JP | 1 |
| Clynes, M; Crown, J; Eustace, AJ; O'Donovan, N | 1 |
| de Groot, J; LaFortune, T; Milano, V; Piao, Y | 1 |
| Chen, TC; Golden, EB; Hofman, FM; Pen, L; Schönthal, AH; Sivakumar, W; Virrey, JJ; Wang, W | 1 |
| Cubitt, CL; Daud, AI; Homsi, J; Jove, R; Messina, JL; Munster, PN; Sullivan, DM; Yu, H; Zhang, S | 1 |
| Bektas, M; Bigner, DD; Friedman, HS; Johnson, SP; Poe, WE | 1 |
| Alvino, E; Bonmassar, E; Brasca, MG; Caporali, S; Castiglia, D; Ciomei, M; Covaciu, C; D'Atri, S; Garbin, A; Levati, L; Starace, G | 1 |
| Slotman, BJ; Van Den Berg, J; van Nifterik, KA; Van Rijn, J | 1 |
| Fan, X; Liu, Y; Ni, S; Qi, H; Wang, C; Wang, X | 1 |
| Algazi, AP; Andrews, SC; Daud, AI; DeConti, RC; Hwang, J; McCalmont, T; Messina, JL; Munster, PN; Sondak, VK; Urbas, P; Weber, JS | 1 |
| Li, Q; Li, W; Lu, W; Tong, H; Zhou, Y | 1 |
| Beberok, A; Buszman, E; Respondek, M; Rok, J; Rzepka, Z; Wrześniok, D | 1 |
| Bradshaw, TD; Lewis, W; Moody, CJ; Stevens, MFG; Summers, HS; Williams, HEL | 1 |
1 trial(s) available for thiazoles and dacarbazine
| Article | Year |
|---|---|
Phase I clinical trial of the Src inhibitor dasatinib with dacarbazine in metastatic melanoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dasatinib; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Pyrimidines; src-Family Kinases; Survival Analysis; Thiazoles; Treatment Outcome | 2012 |
17 other study(ies) available for thiazoles and dacarbazine
| Article | Year |
|---|---|
Sensitization of a human ovarian cancer cell line to temozolomide by simultaneous attenuation of the Bcl-2 antiapoptotic protein and DNA repair by O6-alkylguanine-DNA alkyltransferase.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; DNA Repair; Dose-Response Relationship, Drug; Female; Humans; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides; Ovarian Neoplasms; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Tetrazolium Salts; Thiazoles; Thionucleotides; Time Factors; Up-Regulation | 2004 |
Pharmaceutical-mediated inactivation of p53 sensitizes U87MG glioma cells to BCNU and temozolomide.
Topics: Antineoplastic Agents, Alkylating; Benzothiazoles; Brain Neoplasms; Carmustine; Dacarbazine; DNA Damage; Drug Interactions; Glioma; Humans; Temozolomide; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2005 |
Desmoid tumors respond to chemotherapy: defying the dogma in oncology.
Topics: Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Fibromatosis, Aggressive; Humans; Meloxicam; Thiazines; Thiazoles | 2006 |
Successful chemotherapeutic modality of doxorubicin plus dacarbazine for the treatment of desmoid tumors in association with familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Adult; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Female; Fibromatosis, Aggressive; Genes, APC; Germ-Line Mutation; Humans; Male; Meloxicam; Retrospective Studies; Thiazines; Thiazoles; Tomography, X-Ray Computed | 2006 |
An orthotopic skull base model of malignant meningioma.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Disease Models, Animal; DNA Modification Methylases; DNA Repair Enzymes; Female; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Meningeal Neoplasms; Meningioma; Mice; Mice, Nude; Neoplasm Transplantation; Skull Base Neoplasms; Temozolomide; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Proteins | 2008 |
Cytotoxic and apoptotic effects of bortezomib and gefitinib compared to alkylating agents on human glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Boronic Acids; Bortezomib; Brain Neoplasms; Carboplatin; Carmustine; Cell Line, Tumor; Dacarbazine; Dose-Response Relationship, Drug; ErbB Receptors; Flow Cytometry; Gefitinib; Glial Fibrillary Acidic Protein; Glioblastoma; Immunohistochemistry; Indicators and Reagents; Mice; Proteasome Inhibitors; Pyrazines; Quinazolines; Rats; Temozolomide; Tetrazolium Salts; Thiazoles | 2008 |
Preclinical evaluation of dasatinib, a potent Src kinase inhibitor, in melanoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Benzenesulfonates; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Dasatinib; Drug Screening Assays, Antitumor; Drug Synergism; Focal Adhesion Protein-Tyrosine Kinases; Humans; Melanoma; Neoplasm Invasiveness; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyridines; Pyrimidines; Receptor, EphA2; Sorafenib; Temozolomide; Thiazoles | 2008 |
Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dacarbazine; Dasatinib; Drug Screening Assays, Antitumor; Drug Synergism; G1 Phase; Glioma; Humans; PTEN Phosphohydrolase; Pyrimidines; Temozolomide; Thiazoles | 2009 |
Glioma-associated endothelial cells are chemoresistant to temozolomide.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Death; Cell Movement; Cell Proliferation; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation, Neoplastic; Glioma; Humans; Male; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Temozolomide; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured | 2009 |
Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma.
Topics: Aniline Compounds; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dacarbazine; Dasatinib; Drug Synergism; Enzyme Activation; Humans; Inhibitory Concentration 50; Melanoma; Nitriles; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Pyrimidines; Quinolines; Skin Neoplasms; src-Family Kinases; Temozolomide; Thiazoles | 2009 |
A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells.
Topics: Aniline Compounds; Antineoplastic Agents, Alkylating; Apoptosis; Caspase 3; Cell Death; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Glioblastoma; Humans; Indicator Dilution Techniques; Oligonucleotide Array Sequence Analysis; Phosphotransferases (Alcohol Group Acceptor); Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Thiazoles | 2009 |
The cyclin-dependent kinase inhibitor PHA-848125 suppresses the in vitro growth of human melanomas sensitive or resistant to temozolomide, and shows synergistic effects in combination with this triazene compound.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinases; Dacarbazine; DNA Mutational Analysis; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Genes, p53; Humans; Melanoma; O(6)-Methylguanine-DNA Methyltransferase; Pyrazoles; Quinazolines; Temozolomide; Tetrazolium Salts; Thiazoles | 2010 |
Anti-tumour effects by a trimodal combination of temozolomide, meloxicam and X-rays in cultures of human glioma cells.
Topics: Antineoplastic Agents, Alkylating; Cell Cycle; Combined Modality Therapy; Cyclooxygenase Inhibitors; Dacarbazine; Glioma; Humans; Meloxicam; Temozolomide; Thiazines; Thiazoles; Time Factors; Tumor Cells, Cultured; X-Rays | 2011 |
Biodegradable microfibers deliver the antitumor drug temozolomide to glioma C6 cells in vitro.
Topics: Antineoplastic Agents, Alkylating; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Delivery Systems; Excipients; Glioma; Humans; Microscopy, Electron, Scanning; Particle Size; Polypropylenes; Temozolomide; Tetrazolium Salts; Thiazoles | 2010 |
Intestinal perforation during chemotherapeutic treatment of intra-abdominal desmoid tumor in patients with Gardner's syndrome: report of two cases.
Topics: Abdominal Neoplasms; Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Doxorubicin; Female; Fibromatosis, Aggressive; Gardner Syndrome; Humans; Intestinal Perforation; Male; Meloxicam; Thiazines; Thiazoles | 2016 |
MIM1, the Mcl-1 - specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Dacarbazine; DNA Damage; Dose-Response Relationship, Drug; Glioblastoma; Humans; Membrane Potential, Mitochondrial; Myeloid Cell Leukemia Sequence 1 Protein; Temozolomide; Thiazoles | 2018 |
Discovery of new imidazotetrazinones with potential to overcome tumor resistance.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioblastoma; Humans; Temozolomide; Thiazoles | 2023 |