thiazoles has been researched along with cyclin d1 in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (6.38) | 18.2507 |
2000's | 28 (59.57) | 29.6817 |
2010's | 14 (29.79) | 24.3611 |
2020's | 2 (4.26) | 2.80 |
Authors | Studies |
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Fasshauer, M; Glaesser, D; Iwig, M | 1 |
Benassi, MS; Ferrari, C; Gamberi, G; Magagnoli, G; Maltarello, MC; Merli, M; Molendini, L; Picci, P; Ragazzini, P; Sollazzo, MR | 1 |
Breyer, MD; Breyer, RM; Davis, L; Guan, YF; Zhang, YH | 1 |
Hupfeld, CJ; Weiss, RH | 1 |
Collins, AR; Hsueh, WA; Kim, S; Law, RE; Liu, Z; Van Herle, AJ; Wakino, S; Yin, F | 1 |
Hiraoka, S; Kitamura, S; Kiyohara, T; Matsuzawa, Y; Miyazaki, Y; Nagasawa, Y; Shinomura, Y; Takakura, R; Toyota, M | 1 |
Kitamura, S; Kiyohara, T; Matsuzawa, Y; Miyazaki, Y; Nagasawa, Y; Shinomura, Y; Toyota, M | 1 |
Bae, MA; Rhee, H; Song, BJ | 1 |
Burghardt, R; Qin, C; Safe, S; Smith, R; Stewart, J; Wormke, M | 1 |
Ethridge, RT; Evers, BM; Hashimoto, K | 1 |
Berger, JP; Bruemmer, D; Fleck, E; Kintscher, U; Law, RE; Liu, J; Moller, DE; Wakino, S | 1 |
Blaschke, F; Bruemmer, D; Kintscher, U; Law, RE; Unger, T | 1 |
Albanese, C; Brownlee, M; Donehower, LA; Fu, M; Harris, EL; Hulit, J; Johns, DC; Jones, JG; Li, Z; Neumeister, P; Novikoff, PM; Pattabiraman, N; Pestell, RG; Rohan, T; Sakamaki, T; Scherer, PE; Wang, C; Whitney, KD; Wu, K; Zhou, JN | 1 |
Aggarwal, BB; Bharti, AC; Shishodia, S; Takada, Y | 1 |
Cherian, MG; Ostrakhovitch, EA | 1 |
Chen, A; Zheng, S | 1 |
Caicedo, E; Choo, DI; Harris, G; Jhanjee, R; Juhn, SK; Ondrey, F; Preciado, D; Silver, R | 1 |
Baek, SJ; Eling, TE; Kim, JS; Sali, T | 1 |
Parent, AD; Tamaki, N; Yin, D; Zhang, JH | 1 |
Gao, X; Wang, H; Zhang, B | 1 |
Chakrabarti, R; Cohen, AN; LoTempio, MM; Ramalingam, TS; Ramamurthy, B; Srivatsan, ES; Steele, HL; Veena, MS; Wang, MB | 1 |
Chan, AT; Chan, CM; Ma, BB; Wong, SC | 1 |
Li, KZ; Li, XJ; Ling, R; Wang, H; Wang, L; Zhao, LN | 1 |
Cekanova, M; Fedorocko, P; Majidi, M; Masi, T; Plummer, HK; Schuller, HM | 1 |
Bhalla, K; Jove, R; Lee, FY; List, A; Nam, S; Smith, D; Vultur, A; Williams, A | 1 |
Dey, S; Snow, DM | 1 |
Fujiwara, H; Inoue, M; Maruyama, R; Minatoguchi, S; Nagatsu, A; Nakagawa, M; Ohno, T; Okubo, M; Takemura, G; Tanabe, H | 1 |
Ding, L; Wu, X; Xie, S; Zhu, S | 1 |
Iba, S; Imoto, M; Kanai, M; Okada, R; Tashiro, E | 1 |
Che, XM; He, DL; Pan, CE; Wang, GR; Wang, XY; Wu, KJ; Zeng, J; Zhao, JH; Zheng, Y | 1 |
Lei, XY; Li, GQ; Xie, J; Zhang, L | 1 |
Chen, R; Cheng, T; Chubb, S; Gandhi, V; Hawtin, RE; Plunkett, W | 1 |
Chen, R; Ding, G; Huang, S; Yuan, Y; Zhang, A | 1 |
Liu, Q; Luo, CL; Shen, SL; Wang, CY; Wu, XH; Xu, X; Zhang, QL; Zhang, YY | 1 |
Liu, ML; Liu, X; Pei, LC; Zhang, YN; Zhang, YQ | 1 |
Fox, TE; Gowda, R; Hengst, J; Madhunapantula, SV; Robertson, GP; Yun, JK | 1 |
Coluccia, AM; De Leo, S; de Luca, E; De Matteis, S; Di Renzo, N; Dini, L; Maffia, M; Palamà, I; Passerini, CG; Reddiconto, G; Toto, C | 1 |
Abdou, AG; Afifi, AF; Elnaidany, NF; Harba, NM | 1 |
Chang, Y; Li, L; Li, X; Li, Z; Lv, F; Ma, W; Tian, T; Wang, X; Wu, J; Zhang, L; Zhang, M | 1 |
Bradshaw, TD; Callero, MA; De Dios, DO; Luzzani, GA; Perez, AI | 1 |
Chen, LZ; Guo, W; He, J; Hu, J; Huang, H; Li, XY; Liang, HP; Luo, AX; Sun, ZY; Wang, ZG; Xing, W; Xu, X; Xu, YS | 1 |
Deng, ZL; Lu, ZJ; Su, J; Wei, YF; Yuan, L; Zhu, C; Zhu, QY | 1 |
Arai, E; Hamada, S; Ikuta, K; Ishiguro, N; Kozawa, E; Nishida, Y; Sakai, T; Urakawa, H | 1 |
Cai, Y; Lu, C; Makala, L; Wu, D | 1 |
Gu, J; Qian, H; Zhu, X | 1 |
Abe, K; Aiba, H; Aoki, Y; Araki, Y; Bolidong, D; Domoto, T; Hayashi, K; Higuchi, T; Igarashi, K; Inatani, H; Minamoto, T; Miwa, S; Takeuchi, A; Taniguchi, Y; Tsuchiya, H; Yamamoto, N; Yonezawa, H | 1 |
Ding, Y; Shi, L; Wang, H; Xu, Z; Yang, Y; Zhang, N; Zhu, M | 1 |
1 review(s) available for thiazoles and cyclin d1
Article | Year |
---|---|
Targeting translation: eIF4E as an emerging anticancer drug target.
Topics: Animals; Antineoplastic Agents; Cyclin D1; Epoxy Compounds; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Macrolides; Neoplasms; Oligonucleotides, Antisense; Protein Biosynthesis; Ribavirin; RNA, Small Interfering; Signal Transduction; Sirolimus; Survivin; Thiazoles; Triterpenes; Vascular Endothelial Growth Factor A | 2016 |
46 other study(ies) available for thiazoles and cyclin d1
Article | Year |
---|---|
Synthesis of proto-oncogene proteins and cyclins depends on intact microfilaments.
Topics: Actin Cytoskeleton; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cyclin A; Cyclin D1; Cyclin E; Cyclins; Cytochalasin D; Fibroblasts; Humans; Protein Biosynthesis; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Thiazoles; Thiazolidines | 1998 |
Expression of G1 phase regulators in MG-63 osteosarcoma cell line.
Topics: Apoptosis; Bone Neoplasms; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Interleukin-6; Osteosarcoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Retinoblastoma Protein; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Carcinoma, Transitional Cell; Carrier Proteins; Cell Death; Chromans; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; G1 Phase; Humans; Immunoblotting; In Situ Hybridization; Ligands; Luciferases; Myelin P2 Protein; Neoplasm Proteins; Nicotinic Acids; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Ribonucleases; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transfection; Tretinoin; Troglitazone; Tumor Cells, Cultured; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 1999 |
TZDs inhibit vascular smooth muscle cell growth independently of the cyclin kinase inhibitors p21 and p27.
Topics: Animals; Becaplermin; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; DNA; Enzyme Inhibitors; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Suppressor Proteins | 2001 |
Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cell Separation; Cell Survival; Chromans; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Ethanol; Flow Cytometry; G1 Phase; Humans; Ligands; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Receptors, Cytoplasmic and Nuclear; Retinoblastoma Protein; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured | 2001 |
PPARgamma agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Line; Cell Line, Transformed; Cell Nucleus; Chromans; Cyclin D1; DNA, Complementary; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Flow Cytometry; Humans; Hypoglycemic Agents; Intestines; Ligands; Luciferases; Plasmids; Promoter Regions, Genetic; ras Proteins; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Troglitazone | 2001 |
Peroxisome proliferator-activated receptor gamma reduces the growth rate of pancreatic cancer cells through the reduction of cyclin D1.
Topics: Alitretinoin; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinoma; Cell Division; Chromans; Cyclin D1; Dose-Response Relationship, Drug; Drug Synergism; G1 Phase; Humans; Pancreatic Neoplasms; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tretinoin; Troglitazone; Tumor Cells, Cultured | 2002 |
Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines.
Topics: Animals; Antineoplastic Agents; Apoptosis; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Chromans; Cyclin A; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Liver Neoplasms; Protein Serine-Threonine Kinases; Rats; Rosiglitazone; Thiazoles; Thiazolidinediones; Troglitazone; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cyclin D1; Cysteine Endopeptidases; Down-Regulation; Estrogen Receptor alpha; G1 Phase; Humans; Multienzyme Complexes; Prostaglandin D2; Proteasome Endopeptidase Complex; Receptors, Cytoplasmic and Nuclear; Receptors, Estrogen; RNA, Messenger; S Phase; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Ubiquitin | 2003 |
Peroxisome proliferator-activated receptor gamma ligand inhibits cell growth and invasion of human pancreatic cancer cells.
Topics: 3T3 Cells; Adenocarcinoma; alpha Catenin; Animals; Antineoplastic Agents; Apoptosis; beta Catenin; Cadherins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Division; Collagen; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Cytoskeletal Proteins; Drug Combinations; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Laminin; Ligands; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Pancreatic Neoplasms; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
A non-thiazolidinedione partial peroxisome proliferator-activated receptor gamma ligand inhibits vascular smooth muscle cell growth.
Topics: Adenoviridae; Animals; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin A; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; G1 Phase; Genetic Vectors; Inhibitory Concentration 50; Ligands; Luciferases; Mitogens; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Retinoblastoma Protein; S Phase; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Tumor Suppressor Proteins | 2003 |
p38 MAP kinase negatively regulates angiotensin II-mediated effects on cell cycle molecules in human coronary smooth muscle cells.
Topics: Angiotensin II; Cell Cycle; Cells, Cultured; Cyclin D1; DNA; Enzyme Inhibitors; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Retinoblastoma Protein; Thiazoles | 2003 |
Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.
Topics: 3T3 Cells; Animals; Breast; Breast Neoplasms; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Cyclin D1; Ecdysterone; Epithelial Cells; Fatty Liver; Female; Gene Expression Regulation; Humans; Mice; Mice, Mutant Strains; Mice, Transgenic; Models, Molecular; Mutation; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Reference Values; Repressor Proteins; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 2003 |
Evidence that receptor activator of nuclear factor (NF)-kappaB ligand can suppress cell proliferation and induce apoptosis through activation of a NF-kappaB-independent and TRAF6-dependent mechanism.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Coloring Agents; Cyclin D1; Cyclin D3; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dimerization; DNA; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Flow Cytometry; G1 Phase; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Ligands; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; Peptides; Poly(ADP-ribose) Polymerases; Proteins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Resting Phase, Cell Cycle; Tetrazolium Salts; Thiazoles; Time Factors; TNF Receptor-Associated Factor 6; Tumor Suppressor Proteins | 2004 |
Differential regulation of signal transduction pathways in wild type and mutated p53 breast cancer epithelial cells by copper and zinc.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Chromones; Copper; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins; Signal Transduction; Thiazoles; Tumor Suppressor Protein p53; Zinc | 2004 |
Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro.
Topics: Animals; Apoptosis; Cell Proliferation; Curcumin; Cyclin D1; Enzyme Inhibitors; Extracellular Matrix; Flow Cytometry; Gene Expression Regulation; Liver; Male; Nitro Compounds; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Transforming Growth Factor beta; Signal Transduction; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Pseudomonas aeruginosa lipopolysaccharide induction of keratinocyte proliferation, NF-kappa B, and cyclin D1 is inhibited by indomethacin.
Topics: Blotting, Western; Cell Line, Transformed; Cell Proliferation; Clone Cells; Cyclin D1; Genes, Reporter; Growth Inhibitors; Humans; I-kappa B Proteins; Indomethacin; Keratinocytes; Lipopolysaccharides; Luciferases; NF-kappa B; NF-KappaB Inhibitor alpha; Pseudomonas aeruginosa; Tetrazolium Salts; Thiazoles; Thymidine; Transfection | 2005 |
The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Down-Regulation; Female; Growth Differentiation Factor 15; Humans; Luciferases; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sulindac; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2005 |
Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity.
Topics: Apoptosis; Benzimidazoles; Blotting, Southern; Blotting, Western; Caspase 3; Caspases; Cell Count; Cell Line, Tumor; Cell Proliferation; Colorimetry; Cyclin D1; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidases; Etoposide; Gene Expression Regulation, Neoplastic; Glioma; Humans; Insulin-Like Growth Factor I; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides, Antisense; Receptor, IGF Type 1; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Tanshinone: an inhibitor of proliferation of vascular smooth muscle cells.
Topics: Abietanes; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Flow Cytometry; Male; Muscle, Smooth, Vascular; Phenanthrenes; Phosphorylation; Rats; Rats, Wistar; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Curcumin suppresses growth of head and neck squamous cell carcinoma.
Topics: Animals; Annexin A5; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Nucleus; Cell Separation; Cell Survival; Curcumin; Cyclin D1; Dose-Response Relationship, Drug; Female; Flow Cytometry; Head and Neck Neoplasms; Humans; I-kappa B Proteins; In Vitro Techniques; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Tetrazolium Salts; Thiazoles | 2005 |
Celecoxib induces dose dependent growth inhibition in nasopharyngeal carcinoma cell lines independent of cyclooxygenase-2 expression.
Topics: Blotting, Western; Celecoxib; Cell Division; Cell Line, Tumor; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Nasopharyngeal Neoplasms; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Tetrazolium Salts; Thiazoles | 2005 |
Overexpression of ribosomal protein L15 is associated with cell proliferation in gastric cancer.
Topics: Agar; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cyclin B; Cyclin B1; Cyclin D1; Down-Regulation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Plasmids; Ribosomal Proteins; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2006 |
Pulmonary fibroblasts stimulate the proliferation of cell lines from human lung adenocarcinomas.
Topics: Adenocarcinoma; Amphiregulin; Animals; Antibodies, Blocking; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Cyclin D1; Cyclin E; EGF Family of Proteins; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Glycoproteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lung; Lung Neoplasms; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Thiazoles; Transforming Growth Factor alpha | 2006 |
Dasatinib (BMS-354825) inhibits Stat5 signaling associated with apoptosis in chronic myelogenous leukemia cells.
Topics: Apoptosis; bcl-X Protein; Cell Count; Cell Survival; Cyclin D1; Dasatinib; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; HL-60 Cells; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphotyrosine; Protein Binding; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Thiazoles | 2007 |
Cocaine exposure in vitro induces apoptosis in fetal locus coeruleus neurons through TNF-alpha-mediated induction of Bax and phosphorylated c-Jun NH(2)-terminal kinase.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Survival; Cells, Cultured; Cocaine; Culture Media; Cyclin D1; Data Interpretation, Statistical; Enzyme-Linked Immunosorbent Assay; Female; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Locus Coeruleus; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Rats; Rats, Long-Evans; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2007 |
Sesquiterpene lactone suppresses vascular smooth muscle cell proliferation and migration via inhibition of cell cycle progression.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cell Cycle; Cell Movement; Cell Proliferation; Chemotaxis; Cyclin D1; Depression, Chemical; G1 Phase; Indicators and Reagents; Lactones; Male; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tetrazolium Salts; Thiazoles | 2007 |
Effect of exogenous bFGF on the proliferation of human adenoid cystic carcinoma ACC-2 cells.
Topics: Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Salivary Gland Neoplasms; Tetrazolium Salts; Thiazoles | 2008 |
Oligomycin induced the proteasomal degradation of cyclin D1 protein.
Topics: Adenoviridae; Blotting, Western; Cell Line; Cyclin D1; Flow Cytometry; Gene Expression; Genes, bcl-1; Genetic Vectors; Humans; Indicators and Reagents; Oligomycins; Plasmids; Proteasome Endopeptidase Complex; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Transfection | 2009 |
Upregulation of human DNA binding protein A (dbpA) in gastric cancer cells.
Topics: Adenomatous Polyposis Coli Protein; Antineoplastic Agents; beta Catenin; Cadherins; CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; Cell Line, Tumor; Coloring Agents; Culture Media, Serum-Free; Cyclin D1; Fluorescent Antibody Technique, Direct; Fluorouracil; Heat-Shock Proteins; Humans; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Transfection; Up-Regulation | 2009 |
Macrophage migration inhibitory factor regulates proliferation of gastric cancer cells via the PI3K/Akt pathway.
Topics: Cell Line, Tumor; Cell Proliferation; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetrazolium Salts; Thiazoles | 2009 |
Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line.
Topics: Cell Cycle; Cell Death; Cell Growth Processes; Cell Line, Tumor; Cyclin D1; Humans; Lymphoma, Mantle-Cell; Myeloid Cell Leukemia Sequence 1 Protein; Oxazoles; Proto-Oncogene Proteins c-bcl-2; RNA, Neoplasm; RNA, Small Nuclear; Thiazoles; Transfection | 2010 |
A PPARgamma agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR intracellular signaling.
Topics: Aldosterone; Animals; Cell Proliferation; Cells, Cultured; Cyclin A; Cyclin D1; ErbB Receptors; Mesangial Cells; Mice; Mineralocorticoid Receptor Antagonists; Nitro Compounds; Phosphatidylinositol 3-Kinases; Phosphorylation; PPAR gamma; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones | 2011 |
HepaCAM induces G1 phase arrest and promotes c-Myc degradation in human renal cell carcinoma.
Topics: Blotting, Western; Carcinoma, Renal Cell; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin D1; G1 Phase; Humans; In Vitro Techniques; Protein Stability; Proteins; Proto-Oncogene Proteins c-myc; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles | 2011 |
Prostaglandin E2 receptor 1 activity regulates cell survival following hypoxia in cultured rat cortical neurons.
Topics: Analysis of Variance; Animals; Annexin A5; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclin D1; Dinoprostone; Dose-Response Relationship, Drug; Embryo, Mammalian; Hydrazines; Hypoxia; Neurons; Oxazepines; Oxygen; Rats; Rats, Wistar; Receptors, Prostaglandin E, EP1 Subtype; Tetrazolium Salts; Thiazoles; Time Factors; Up-Regulation | 2012 |
Targeting sphingosine kinase-1 to inhibit melanoma.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Fibroblasts; G1 Phase Cell Cycle Checkpoints; Humans; Lysophospholipids; Melanocytes; Melanoma; Mice; Molecular Targeted Therapy; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resting Phase, Cell Cycle; RNA, Small Interfering; Skin Neoplasms; Sphingosine; Staurosporine; Thiazoles; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors, preserving normal stem cells.
Topics: Antigens, CD34; Apoptosis; Benzamides; beta Catenin; Blotting, Western; Cell Nucleus; Cells, Cultured; Cyclin D1; Cytokines; Dasatinib; Drug Synergism; Fusion Proteins, bcr-abl; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hematopoietic Stem Cells; Humans; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Maleimides; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Neoplastic Stem Cells; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Signal Transduction; Thiazoles | 2012 |
Assessment of Cryptosporidium parvum infection in immunocompetent and immunocompromised mice and its role in triggering intestinal dysplasia.
Topics: Animals; Antiparasitic Agents; Cryptosporidiosis; Cryptosporidium parvum; Cyclin D1; Disease Models, Animal; Female; Immunocompromised Host; Intestinal Mucosa; Intestines; Liver; Mice; Nitro Compounds; Oocysts; Thiazoles | 2013 |
Six1 promotes proliferation of pancreatic cancer cells via upregulation of cyclin D1 expression.
Topics: Analysis of Variance; Animals; Blotting, Western; Bromodeoxyuridine; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin D1; DNA Primers; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Mice; Mice, Inbred BALB C; Microarray Analysis; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay | 2013 |
Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cells, Cultured; Cyclin D1; Cytochrome P-450 CYP1A1; DNA Damage; Female; Flow Cytometry; Humans; Microscopy, Confocal; Ovarian Neoplasms; Phosphorylation; Reactive Oxygen Species; Thiazoles | 2013 |
SUMO-2 promotes mRNA translation by enhancing interaction between eIF4E and eIF4G.
Topics: Apoptosis; Cell Proliferation; Cyclin D1; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Gene Expression Regulation; Genes, Reporter; HCT116 Cells; Humans; Hydrazones; Multiprotein Complexes; Protein Binding; Protein Biosynthesis; Proto-Oncogene Proteins c-myc; RNA Caps; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Thiazoles | 2014 |
[Indirubin inhibits the proliferation of prostate cancer PC-3 cells].
Topics: Antibiotics, Antineoplastic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Cyclin D1; Dose-Response Relationship, Drug; Genes, myc; Humans; Indoles; Male; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-myc; Tetrazolium Salts; Thiazoles | 2015 |
Characteristics of cultured desmoid cells with different CTNNB1 mutation status.
Topics: Adult; Antineoplastic Agents; Apoptosis; Axin Protein; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclooxygenase 2; DNA Mutational Analysis; Fibromatosis, Aggressive; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Meloxicam; Mutation; RNA, Messenger; Thiazines; Thiazoles; Tumor Cells, Cultured; Wnt Signaling Pathway; Young Adult | 2016 |
Esculetin Attenuates the Growth of Lung Cancer by Downregulating Wnt Targeted Genes and Suppressing NF-κB.
Topics: Animals; Apoptosis; beta Catenin; Carcinoma, Lewis Lung; Cell Proliferation; Coloring Agents; Cyclin D1; Down-Regulation; Female; Heterografts; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; NF-kappa B; Salivary alpha-Amylases; Tetrazolium Salts; Thiazoles; Tumor Stem Cell Assay; Umbelliferones; Wnt Proteins | 2018 |
Glycogen synthase kinase 3β as a potential therapeutic target in synovial sarcoma and fibrosarcoma.
Topics: Animals; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase 4; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Injections, Intraperitoneal; Maleimides; Mice; Phosphorylation; RNA Interference; Sarcoma, Synovial; Thiazoles; Up-Regulation; Urea; Xenograft Model Antitumor Assays | 2020 |
Ribonucleotide reductase holoenzyme inhibitor COH29 interacts with deubiquitinase ubiquitin-specific protease 2 and downregulates its substrate protein cyclin D1.
Topics: Benzamides; Cyclin D1; Down-Regulation; Enzyme Inhibitors; Holoenzymes; Humans; Neoplasms; Ribonucleotide Reductases; Thiazoles; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases | 2022 |