Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and cyc 116

thiazoles has been researched along with cyc 116 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Blake, DG; Clarke, RG; Fischer, PM; Glover, DM; Grabarek, JB; Griffiths, G; Jackson, RC; Jackson, W; Kontopidis, G; Lane, DP; McClue, SJ; McInnes, C; Meades, C; Mezna, M; Midgley, CA; Plater, A; Scaërou, F; Stuart, I; Thomas, MP; Wang, S; Wood, G; Zheleva, DI1
Davidson, FA; Jackson, RC; Kamei, H; Zheleva, D1
Hu, WX; Li, HB; Lu, KQ; Pei, W; Shi, HB; Zhu, XR1
Gadher, SJ; Hajduch, M; Halada, P; Hrabakova, R; Kollareddy, M; Kovarova, H; Tyleckova, J1
Feng, JY; Meng, HT; Qian, WB; You, LS; Zhou, YH1
Berstler, J; Chauvin, M; Donahoe, PK; Hartland, K; Jensen, MM; Li, Y; Meinsohn, MC; Nagykery, N; Pepin, D; Sicher, NA; Suliman, R; Wei, L1

Other Studies

6 other study(ies) available for thiazoles and cyc 116

ArticleYear
Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors.
    Journal of medicinal chemistry, 2010, Jun-10, Volume: 53, Issue:11

    Topics: Adenosine Triphosphate; Animals; Aurora Kinase A; Aurora Kinases; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Humans; Inhibitory Concentration 50; Mice; Mitosis; Models, Molecular; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Substrate Specificity; Thiazoles; Xenograft Model Antitumor Assays

2010
An integrated pharmacokinetic-pharmacodynamic model for an Aurora kinase inhibitor.
    Journal of pharmacokinetics and pharmacodynamics, 2010, Volume: 37, Issue:4

    Topics: Animals; Aurora Kinases; Cell Line, Tumor; Computer Simulation; Dose-Response Relationship, Drug; Drug Discovery; Humans; Mice; Models, Biological; Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Thiazoles

2010
Synthesis of novel thiazolyl-pyrimidines and their anticancer activity in vitro.
    Archiv der Pharmazie, 2011, Volume: 344, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiazoles

2011
Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy.
    Journal of proteome research, 2013, Jan-04, Volume: 12, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Antineoplastic Agents; Apoptosis; Aurora Kinases; Benzamides; Drug Resistance, Neoplasm; GTP-Binding Proteins; HCT116 Cells; Humans; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Quinazolines; Thiazoles; Tumor Suppressor Protein p53

2013
Matrine and CYC116 synergistically inhibit growth and induce apoptosis in multiple myeloma cells.
    Chinese journal of integrative medicine, 2015, Volume: 21, Issue:8

    Topics: Alkaloids; Apoptosis; Cell Division; Cell Line, Tumor; Humans; Matrines; Multiple Myeloma; Pyrimidines; Quinolizines; Thiazoles

2015
A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives.
    Proceedings of the National Academy of Sciences of the United States of America, 2022, 04-12, Volume: 119, Issue:15

    Topics: Animals; Anthracenes; Contraceptive Agents; Drug Evaluation, Preclinical; Drug Repositioning; Female; Humans; Mice; Nitriles; Ovarian Follicle; Pyrazoles; Pyrimidines; Rats; Receptors, Peptide; Receptors, Transforming Growth Factor beta; Small Molecule Libraries; Thiazoles

2022