Page last updated: 2024-08-21

thiazoles and cl 075

thiazoles has been researched along with cl 075 in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (4.55)	29.6817
2010's	21 (95.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bigalke, I; Bürdek, M; Frankenberger, B; Geiger, C; Javorovic, M; Mosetter, B; Schendel, DJ; Spranger, S; Tippmer, S; Wilde, S	1
Agouna-Deciat, O; Banchereau, J; Blanck, JP; Cao, Y; Flamar, AL; Klechevsky, E; Klucar, P; Liu, M; O'Bar, A; Palucka, AK; Reiter, Y; Thompson-Snipes, L; Zurawski, G; Zurawski, S	1
Bontkes, HJ; de Jong, EC; Mol, BM; Moreno, M; Scheper, RJ; van den Eertwegh, AJ; Verheijen, RH; von Blomberg, BM; von Mensdorff-Pouilly, S	1
Du, J; Gao, M; Qu, C; Randolph, GJ; Ren, S; Wei, Y; Wu, Z	1
Fleenor, S; Goeken, JA; Layer, T; Lenert, P; Steele, A	1
French, M; Kamarulzaman, A; Lim, A; Price, P; Tan, DB; Tan, HY; Yong, YK	1
Butchi, NB; Du, M; Peterson, KE; Woods, T	1
Bala, S; Catalano, D; Kodys, K; Pang, M; Szabo, G	1
He, ZQ; Ma, J; Su, ZL; Tong, J; Wang, KW; Wang, SJ; Xu, HX; Yang, H; Zhao, YX; Zheng, D	1
Chou, MH; Chuang, JH; Du, YY; Hsieh, CS; Huang, YH; Lin, TM; Tsai, PC	1
Dietsch, GN; Dowling, DJ; Hershberg, RM; Levy, O; Matthews, MA; Palmer, CD; Prokopowicz, ZM; Tan, Z	1
Miyake, K; Ohto, U; Shibata, T; Shimizu, T; Tanji, H	1
Bover, L; Harline, ML; Liu, YJ; Sugimoto, N; Voo, KS; Weng, J	1
Briercheck, E; Butchar, JP; Byrd, JC; Caligiuri, M; Cheney, C; Dietsch, GN; Elavazhagan, S; Fang, H; Fatehchand, K; Gautam, S; Hershberg, RM; Mo, X; Reader, B; Ren, L; Santhanam, V; Tridandapani, S; Vasilakos, JP	1
Belambri, SA; Boussetta, T; Dang, PM; El-Benna, J; Gougerot-Pocidalo, MA; Hurtado-Nedelec, M; Makni-Maalej, K; Marzaioli, V	1
De Coen, R; De Geest, BG; Hoogenboom, R; Laplace, D; Louage, B; Lybaert, L; Maji, S; Vanparijs, N	1
Gani, R; Lee, S; Price, P; Saraswati, H; Tan, D; Yunihastuti, E	1
Chai, HH; Cho, YM; Choi, BH; Lim, D; Suk, JE	1
Dreyfus, DH; Faggioni, A; Farina, A; Farina, GA; Lacconi, V; Lenna, S; Morrone, S; Peruzzi, G; Quarta, S; Rosato, E; Trojanowska, M; Vestri, AR; York, M	1
Affandi, AJ; Boes, M; Cossu, M; Radstake, TRDJ; Silva-Cardoso, SC; Spel, L; van Roon, JAG	1
Guinet, E; Nouri-Shirazi, M; Nourishirazi, E; Tamjidi, S	1
Chen, J; Li, S; Li, T; Liu, YJ; Lv, X; Qi, C; Wu, J; Xu, L; Zang, G; Zhang, M	1

Other Studies

22 other study(ies) available for thiazoles and cl 075

Article	Year
Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075. Journal of immunology (Baltimore, Md. : 1950), 2010, Jul-01, Volume: 185, Issue:1 Topics: Adjuvants, Immunologic; Cancer Vaccines; Cell Differentiation; Cell Movement; Cell Polarity; Cells, Cultured; Coculture Techniques; Cytokines; Dendritic Cells; Humans; Imidazoles; Immunotherapy, Adoptive; Interferon-gamma; Killer Cells, Natural; Ligands; Lymphocyte Activation; Poly I-C; Quinolines; T-Lymphocytes, Cytotoxic; Th1 Cells; Thiazoles; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 8	2010
Cross-priming CD8+ T cells by targeting antigens to human dendritic cells through DCIR. Blood, 2010, Sep-09, Volume: 116, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antigens; Antigens, Neoplasm; B-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Cross-Priming; Dendritic Cells; Flow Cytometry; gag Gene Products, Human Immunodeficiency Virus; Humans; Langerhans Cells; Lectins, C-Type; MART-1 Antigen; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Monocytes; Neoplasm Proteins; Quinolines; Receptors, Immunologic; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8	2010
Differential indirect activation of human invariant natural killer T cells by Toll-like receptor agonists. Immunotherapy, 2009, Volume: 1, Issue:4 Topics: Cell Communication; Cell Differentiation; Cells, Cultured; Dendritic Cells; Flagellin; Humans; Interferon-gamma; Lipopolysaccharides; Lymphocyte Activation; Natural Killer T-Cells; Oligodeoxyribonucleotides; Peptidoglycan; Poly I-C; Quinolines; Thiazoles; Toll-Like Receptors	2009
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine, 2010, Aug-31, Volume: 28, Issue:38 Topics: Alum Compounds; Aminoquinolines; Animals; Antibodies, Viral; Antigen-Presenting Cells; Cell Differentiation; Cells, Cultured; Dendritic Cells; Hepatitis B Surface Antigens; Humans; Imidazoles; Immunoglobulin G; Interferon-gamma; Interleukin-5; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Quinolines; Spleen; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8	2010
Engagement of the B cell receptor for antigen differentially affects B cell responses to Toll-like receptor-7 agonists and antagonists in BXSB mice. Clinical and experimental immunology, 2011, Volume: 163, Issue:3 Topics: Animals; Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocytes; Cell Proliferation; Drug Synergism; Female; Interleukin-6; Lupus Erythematosus, Systemic; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Oligodeoxyribonucleotides; Quinolines; Receptors, Antigen, B-Cell; Signal Transduction; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 9	2011
Robust interferon-α and IL-12 responses by dendritic cells are related to efficient CD4+ T-cell recovery in HIV patients on ART. Clinical immunology (Orlando, Fla.), 2011, Volume: 139, Issue:2 Topics: ADP-ribosyl Cyclase 1; Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Dendritic Cells; HIV Infections; HLA-DR Antigens; Humans; Interferon-alpha; Interleukin-12; Leukocyte Count; Lymphocyte Activation; Male; Membrane Glycoproteins; Middle Aged; Oligodeoxyribonucleotides; Quinolines; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9	2011
Poly-thymidine oligonucleotides mediate activation of murine glial cells primarily through TLR7, not TLR8. PloS one, 2011, Volume: 6, Issue:7 Topics: Animals; Cell Shape; Cerebral Cortex; Cytokines; Down-Regulation; Endocytosis; Endosomes; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Neuroglia; Oligonucleotides; Poly T; Quinolines; RNA, Messenger; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8; Up-Regulation	2011
Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. BMC immunology, 2011, Sep-30, Volume: 12 Topics: Cells, Cultured; Ethanol; Humans; Immunity, Innate; Inflammation Mediators; Interferon Type I; Leukocytes, Mononuclear; Lipopolysaccharides; Quinolines; Thiazoles; Toll-Like Receptor 4; Toll-Like Receptor 8; Tumor Necrosis Factor-alpha	2011
[Expression of TLR8 in human cervical cancer HeLa cells and the effect of TLR8 agonist on the cell proliferation and apoptosis]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cisplatin; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Proto-Oncogene Proteins c-bcl-2; Quinolines; RNA, Messenger; Thiazoles; Toll-Like Receptor 8; Up-Regulation; Vascular Endothelial Growth Factor A	2011
Selective activation of Toll-like receptor 7 in activated hepatic stellate cells may modulate their profibrogenic phenotype. The Biochemical journal, 2012, Oct-01, Volume: 447, Issue:1 Topics: Actins; Animals; Cell Line; Cell Movement; Cell Proliferation; Collagen Type I; Gene Expression; Hepatic Stellate Cells; Jaundice, Obstructive; Liver Cirrhosis; Male; Phenotype; Quinolines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Thiazoles; Toll-Like Receptor 7	2012
The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes. PloS one, 2013, Volume: 8, Issue:3 Topics: Adult; Analysis of Variance; Benzazepines; Dendritic Cells; Flow Cytometry; HEK293 Cells; Humans; Imidazoles; Infant, Newborn; Leukocytes; Lipid A; Quinolines; Thiazoles; Toll-Like Receptor 8	2013
Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands. Science (New York, N.Y.), 2013, Mar-22, Volume: 339, Issue:6126 Topics: Amino Acid Sequence; Crystallography, X-Ray; Humans; Hydrogen Bonding; Imidazoles; Ligands; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Binding; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Quinolines; Signal Transduction; Thiazoles; Toll-Like Receptor 8	2013
Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells. Journal of immunology (Baltimore, Md. : 1950), 2014, Jul-15, Volume: 193, Issue:2 Topics: Adult; Analysis of Variance; B-Lymphocytes; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Flagellin; Forkhead Transcription Factors; Humans; Imidazoles; Interferon-gamma; Interleukin-10; Interleukin-6; Killer Cells, Natural; Leukocytes, Mononuclear; Lipopeptides; Lipopolysaccharides; Lymphocyte Activation; Quinolines; T-Lymphocytes, Regulatory; Thiazoles; Toll-Like Receptors; Tumor Necrosis Factor-alpha	2014
Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity. Journal of immunology (Baltimore, Md. : 1950), 2015, Mar-15, Volume: 194, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Angiotensinogen; Antibodies, Monoclonal, Humanized; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Blotting, Western; Cells, Cultured; Cetuximab; Cluster Analysis; Dose-Response Relationship, Drug; Granzymes; Humans; Imidazoles; Interleukin-2; Monocytes; NF-kappa B; Oligonucleotide Array Sequence Analysis; Perforin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Time Factors; Toll-Like Receptor 8; Transcriptome	2015
TLR8, but not TLR7, induces the priming of the NADPH oxidase activation in human neutrophils. Journal of leukocyte biology, 2015, Volume: 97, Issue:6 Topics: Chemotaxis, Leukocyte; Enzyme Activation; Gene Expression Regulation; Guanosine; Humans; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Naphthoquinones; Neutrophils; NIMA-Interacting Peptidylprolyl Isomerase; p38 Mitogen-Activated Protein Kinases; Peptidylprolyl Isomerase; Phosphorylation; Primary Cell Culture; Quinolines; Reactive Oxygen Species; Signal Transduction; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8	2015
Transiently responsive protein-polymer conjugates via a 'grafting-from' RAFT approach for intracellular co-delivery of proteins and immune-modulators. Chemical communications (Cambridge, England), 2015, Sep-21, Volume: 51, Issue:73 Topics: Acrylamides; Animals; Cell Line; Dendritic Cells; Dioxolanes; Hydrogen-Ion Concentration; Hydrolysis; Immunologic Factors; Mice; Nanoparticles; Polymerization; Polymers; Protein Conformation; Quinolines; Serum Albumin, Bovine; Solubility; Temperature; Thiazoles; Water	2015
Increased proportions of dendritic cells and recovery of IFNγ responses in HIV/HCV co-infected patients receiving ART. Human immunology, 2016, Volume: 77, Issue:1 Topics: Adolescent; Adult; Antiretroviral Therapy, Highly Active; Arthritis, Infectious; Cells, Cultured; Coinfection; Cytokines; Dendritic Cells; Hepacivirus; Hepatitis C; HIV; HIV Infections; Humans; Indonesia; Male; Middle Aged; Quinolines; Thiazoles; Young Adult	2016
Design of anti-BVDV drug based on common chemical features, their interaction, and scaffolds of TLR8 agonists. International journal of biological macromolecules, 2016, Volume: 92 Topics: Amino Acid Sequence; Aminoquinolines; Animals; Antiviral Agents; Binding Sites; Cattle; Diarrhea Virus 1, Bovine Viral; Drug Design; Humans; Imidazoles; Imiquimod; Molecular Docking Simulation; Phylogeny; Protein Binding; Protein Domains; Protein Structure, Secondary; Quinolines; Sequence Alignment; Species Specificity; Structural Homology, Protein; Thiazoles; Toll-Like Receptor 8; Viral Nonstructural Proteins	2016
Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes. Arthritis research & therapy, 2017, 02-28, Volume: 19, Issue:1 Topics: Adult; Aged; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Epstein-Barr Virus Infections; Female; Gene Expression; Gene Expression Profiling; Herpesvirus 4, Human; Host-Pathogen Interactions; Humans; Immunity, Innate; Male; Middle Aged; Monocytes; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Scleroderma, Systemic; Thiazoles; Toll-Like Receptor 8; Virus Replication; Young Adult	2017
CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells. Journal of immunology (Baltimore, Md. : 1950), 2017, 07-01, Volume: 199, Issue:1 Topics: Antigens, CD; B7-2 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; CD83 Antigen; Cell Differentiation; Cells, Cultured; Coculture Techniques; Dendritic Cells; Escherichia coli; Escherichia coli Infections; Genes, MHC Class I; Humans; Imidazoles; Immunoglobulins; Interleukin-12; Lymphocyte Activation; Membrane Glycoproteins; Phenotype; Platelet Factor 4; Poly I-C; Quinolines; Thiazoles; Tumor Necrosis Factor-alpha	2017
Combination of TLR8 and TLR4 agonists reduces the degrading effects of nicotine on DC-NK mediated effector T cell generation. International immunopharmacology, 2018, Volume: 61 Topics: Cell Differentiation; Cells, Cultured; Cigarette Smoking; Coculture Techniques; Dendritic Cells; Drug Therapy, Combination; Humans; Immunosuppression Therapy; Interferon-gamma; Killer Cells, Natural; Lipid A; Lymphocyte Activation; Nicotine; Quinolines; T-Lymphocytes, Cytotoxic; Th1 Cells; Thiazoles; Toll-Like Receptor 4; Toll-Like Receptor 8	2018
pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG. Journal of immunology research, 2019, Volume: 2019 Topics: Animals; Cell Differentiation; Cytokines; Dendritic Cells; Female; Imidazoles; Imiquimod; Interferon Inducers; Interferon Type I; Ligands; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides; Quinolines; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8	2019