Page last updated: 2024-08-21

thiazoles and chalcone

thiazoles has been researched along with chalcone in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's4 (36.36)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Geronikaki, A; Kourounakis, PN; Sotiropoulou, E1
Ansari, WH; Dommisse, R; Jonckers, T; Lemière, G; Singh, SP1
Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW1
Jung, SH; Keum, SR; Kim-Pak, Y; Lee, HK; Lim, SS; Ohuchi, K; Park, KS; Park, SY; Shin, HK; Shin, KH1
Abiko, Y; Akihisa, T; Kimura, Y; Motani, K; Nagai, H; Okano, S; Shibata, Y; Suzuki, T; Tabata, K1
Bharathi, EV; Dastagiri, D; Kamal, A; Pal, D; Pal-Bhadra, M; Pushpavalli, SN; Ramaiah, MJ; Reddy, JS; Srinivas, C1
Kamal, A; Kashi Reddy, M; Viswanath, A1
Kushwaha, V; Modukuri, RK; Murthy, PK; Rao, KB; Sashidhara, KV; Verma, R1
Balakrishna, M; Faazil, S; Kamal, A; Nayak, VL; Nimbarte, VD; Shaik, TB1
Jain, S; Vaidya, A; Yadav, P; Yadav, R1
Akhtar, T; Aktaş, A; Ehsan, M; Haroon, M; Iqbal, H; Tahir, E1

Reviews

2 review(s) available for thiazoles and chalcone

ArticleYear
The design and development of imidazothiazole-chalcone derivatives as potential anticancer drugs.
    Expert opinion on drug discovery, 2013, Volume: 8, Issue:3

    Topics: Animals; Antineoplastic Agents; Chalcone; Drug Design; Humans; Imidazoles; Thiazoles

2013
Caspase-3: A primary target for natural and synthetic compounds for cancer therapy.
    Chemical biology & drug design, 2021, Volume: 98, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Chalcone; Drug Screening Assays, Antitumor; Humans; Hydrazones; Indolequinones; Quinazolines; Quinazolinones; Structure-Activity Relationship; Thiazoles

2021

Other Studies

9 other study(ies) available for thiazoles and chalcone

ArticleYear
Synthesis and physicochemical study (pka, logP) of some new thiazole derivatives with probable local anaesthetic activity.
    Die Pharmazie, 1993, Volume: 48, Issue:11

    Topics: Anesthetics, Local; Animals; Anura; Chalcone; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mass Spectrometry; Sciatic Nerve; Structure-Activity Relationship; Thiazoles

1993
Bifunctional derivative of p,p'-dichlorochalcone. Part III. Synthesis and study for cytotoxic activity of a new compound, 2-[2,2-bis(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-thiazolidin-4-one from p,p'-dichlorochalcone.
    European journal of medicinal chemistry, 2002, Volume: 37, Issue:1

    Topics: Antineoplastic Agents; Chalcone; Chalcones; Chlorobenzenes; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Thiazoles; Thiazolidines; Tumor Cells, Cultured

2002
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19

    Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators

2005
Synthesis and PPAR-gamma ligand-binding activity of the new series of 2'-hydroxychalcone and thiazolidinedione derivatives.
    Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:3

    Topics: Chalcone; Chalcones; Indicators and Reagents; Ligands; Luciferases; PPAR gamma; Reverse Transcriptase Polymerase Chain Reaction; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Transfection

2006
Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma.
    Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:4

    Topics: Angelica; Antineoplastic Agents, Phytogenic; Apoptosis; Benzimidazoles; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Chalcone; Down-Regulation; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Fluorescent Dyes; Humans; Neoplasm Proteins; Neuroblastoma; Plant Stems; Proteomics; Reactive Oxygen Species; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Tetrazolium Salts; Thiazoles

2008
Synthesis of imidazothiazole-chalcone derivatives as anticancer and apoptosis inducing agents.
    ChemMedChem, 2010, Nov-08, Volume: 5, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Caspase 9; Cell Cycle; Cell Line, Tumor; Chalcone; Cyclin-Dependent Kinases; Cyclins; Female; Humans; Imidazoles; NF-kappa B; Thiazoles

2010
Synthesis and antifilarial activity of chalcone-thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: Animals; Brugia malayi; Chalcone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Filariasis; Filaricides; Gerbillinae; Male; Molecular Structure; Murinae; Parasitic Sensitivity Tests; Structure-Activity Relationship; Thiazoles

2014
Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    ChemMedChem, 2014, Volume: 9, Issue:12

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chalcone; DNA Fragmentation; Drug Design; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; HeLa Cells; HT29 Cells; Humans; Imidazoles; Immunohistochemistry; M Phase Cell Cycle Checkpoints; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship; Thiazoles; Tubulin; Tubulin Modulators

2014
Synthesis of Thiazole-Chalcone Hybrid Molecules: Antioxidant, Alpha(α)-Amylase Inhibition and Docking Studies.
    Chemistry & biodiversity, 2023, Volume: 20, Issue:5

    Topics: alpha-Amylases; Antioxidants; Chalcone; Chalcones; Humans; Molecular Docking Simulation; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Thiazoles

2023