Page last updated: 2024-08-21

thiazoles and cardiovascular agents

thiazoles has been researched along with cardiovascular agents in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's8 (40.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Burak, K; Machoń, Z1
el-Sayed, OA; Farghaly, AM; Habib, NS; Khalil, MA1
De Keyser, J; Diener, HC; Hacke, W; Hantson, L; Hennerici, M; Rådberg, J1
Arita, J; Eto, K; Hashimoto, K; Ni, C; Sugiyama, A; Xue, YX1
Aronowski, J; Grotta, JC; Strong, R1
Crabbé, R; Gheuens, J; Hantson, L; Tritsmans, L; Van Rooy, P1
Adachi, Y; Akima, M; Fukazawa, M; Kato, T; Suzuki, Y; Tamura, K1
Lodder, J1
Fisher, M; Schaebitz, W1
Anthonsen, T; Berg, TC; Hoff, BH; Liu, HL1
HOPPE, JO; LUDUENA, FP1
Bakris, GL; Bank, AJ; Kass, DA; Neutel, JM; Oparil, S; Preston, RA1
Cooper, ME1
Bruno, C; Carocci, A; Catalano, A; Cavalluzzi, MM; Corbo, F; Franchini, C; Lentini, G; Tortorella, V1
Chiang Boey, FY; Huang, CL; Kumar, S; Loo, JS; Steele, TW; Venkatraman, SS; Widjaja, E1
Hartog, JW; Hillege, HL; Hummel, YM; Posma, JL; van Veldhuisen, DJ; van Wijk, LM; Voors, AA; Willemsen, S1
Chen, S; Lee, F; Matsushima, N; Mendell, J; Noveck, R; Shi, M; Zahir, H; Zhang, G1
Fang, B; Kang, Y; Liu, X; Qin, J; Xu, Z; Zang, C1
Bridgeman, MB; Dalal, KS1
Pu, WT; Wang, S1

Reviews

3 review(s) available for thiazoles and cardiovascular agents

ArticleYear
An overview of acute stroke therapy: past, present, and future.
    Archives of internal medicine, 2000, Nov-27, Volume: 160, Issue:21

    Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy

2000
Advanced glycation end-product cross-link breakers. A novel approach to cardiovascular pathologies related to the aging process.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 2

    Topics: Aging; Animals; Blood Pressure; Blood Vessels; Cardiovascular Agents; Cardiovascular Diseases; Controlled Clinical Trials as Topic; Glycation End Products, Advanced; Heart Failure; Humans; Hypertension; Thiazoles

2004
Importance of advanced glycation end products in diabetes-associated cardiovascular and renal disease.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 2

    Topics: Animals; Atherosclerosis; Blood Glucose; Cardiomyopathies; Cardiovascular Agents; Diabetic Angiopathies; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Humans; Myocardium; Thiazoles

2004

Trials

4 trial(s) available for thiazoles and cardiovascular agents

ArticleYear
Lubeluzole in acute ischemic stroke. A double-blind, placebo-controlled phase II trial. Lubeluzole International Study Group.
    Stroke, 1996, Volume: 27, Issue:1

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Cardiovascular Agents; Carotid Artery Diseases; Cerebrovascular Disorders; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Injections, Intravenous; Logistic Models; Male; Middle Aged; Multivariate Analysis; Piperidines; Placebos; Safety; Thiazoles

1996
The safety and tolerability of single intravenous doses of lubeluzole (Prosynap) in healthy volunteers.
    International journal of clinical pharmacology and therapeutics, 1997, Volume: 35, Issue:11

    Topics: Adult; Cardiovascular Agents; Dose-Response Relationship, Drug; Electrocardiography; Hemodynamics; Humans; Injections, Intravenous; Male; Piperidines; Single-Blind Method; Thiazoles

1997
Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure.
    European journal of heart failure, 2011, Volume: 13, Issue:8

    Topics: Aged; Cardiovascular Agents; Chronic Disease; Diagnostic Techniques, Cardiovascular; Double-Blind Method; Exercise Tolerance; Female; Glycation End Products, Advanced; Heart Failure; Humans; Male; Middle Aged; Prospective Studies; Thiazoles

2011
Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2013, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Anticoagulants; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiovascular Agents; Cohort Studies; Cross-Over Studies; Drug Interactions; Factor Xa Inhibitors; Female; Humans; Male; Pyridines; Thiazoles; Young Adult

2013

Other Studies

13 other study(ies) available for thiazoles and cardiovascular agents

ArticleYear
Synthesis of isothiazole derivatives with potential biological activity.
    Die Pharmazie, 1992, Volume: 47, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiovascular Agents; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Rats; Spectrophotometry, Infrared; Thiazoles

1992
Synthesis of some thiazole-, 1,3,4-thiadiazole-, and 4H-1,2,4-triazole derivatives of pyrazolo[3,4-b]quinoline.
    Archiv der Pharmazie, 1991, Volume: 324, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anura; Bacteria; Cardiovascular Agents; Heart Rate; In Vitro Techniques; Microbial Sensitivity Tests; Myocardial Contraction; Pyrazoles; Quinolines; Thiadiazoles; Thiazoles

1991
Effects of the antihypoxic and neuroprotective drug, lubeluzole, on repolarization phase of canine heart assessed by monophasic action potential recording.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:1

    Topics: Action Potentials; Animals; Blood Pressure; Cardiac Catheterization; Cardiovascular Agents; Disease Models, Animal; Dogs; Electrocardiography; Heart; Heart Rate; Injections, Intravenous; Microelectrodes; Myocardium; Neuroprotective Agents; Piperidines; Rats; Thiazoles

1996
Combined neuroprotection and reperfusion therapy for stroke. Effect of lubeluzole and diaspirin cross-linked hemoglobin in experimental focal ischemia.
    Stroke, 1996, Volume: 27, Issue:9

    Topics: Animals; Aspirin; Cardiovascular Agents; Cerebral Infarction; Cerebrovascular Disorders; Drug Therapy, Combination; Hemodilution; Hemoglobins; Male; Neuroprotective Agents; Piperidines; Rats; Rats, Inbred Strains; Reperfusion; Thiazoles

1996
CP-060S, a novel cardioprotective drug, limits myocardial infarct size in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:3

    Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Dogs; Hemodynamics; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Thiazoles; Thiazolidines

1998
Lubeluzole treatment of acute ischemic stroke.
    Stroke, 1998, Volume: 29, Issue:5

    Topics: Acute Disease; Brain Ischemia; Cardiovascular Agents; Cerebrovascular Disorders; Humans; Piperidines; Thiazoles

1998
Synthesis of the antistroke drug lubeluzole and its enantiomer. Lipase-catalyzed resolution of chiral building block.
    Chirality, 2001, Volume: 13, Issue:3

    Topics: Cardiovascular Agents; Catalysis; Lipase; Piperidines; Propanols; Stereoisomerism; Substrate Specificity; Thiazoles

2001
2-phenyl-4-thiazolidone derivatives as local anesthetics.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1951, Volume: 40, Issue:3

    Topics: Anesthetics; Anesthetics, Local; Cardiovascular Agents; Thiazoles

1951
Facile, alternative route to lubeluzole, its enantiomer, and the racemate.
    Chirality, 2006, May-05, Volume: 18, Issue:4

    Topics: Cardiovascular Agents; Molecular Structure; Piperidines; Stereoisomerism; Thiazoles

2006
High-throughput screening of PLGA thin films utilizing hydrophobic fluorescent dyes for hydrophobic drug compounds.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

    Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coated Materials, Biocompatible; Coumarins; Delayed-Action Preparations; Drug Carriers; Fluoresceins; Fluorescent Dyes; High-Throughput Screening Assays; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy; Microscopy, Electron, Scanning; Molecular Structure; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rhodamines; Solubility; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Surface Properties; Technology, Pharmaceutical; Thiazoles

2011
Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cells.
    Drug research, 2014, Volume: 64, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cardiovascular Agents; Cell Line; Coloring Agents; Cytochromes c; Diosgenin; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; L-Lactate Dehydrogenase; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tetrazolium Salts; Thiazoles

2014
Cardiovascular drugs.
    Nursing, 2017, Volume: 47, Issue:11

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzazepines; Cardiovascular Agents; Humans; Ivabradine; Pyridines; Thiazoles

2017
Calcific aortic valve disease: turning therapeutic discovery up a notch.
    Nature reviews. Cardiology, 2021, Volume: 18, Issue:5

    Topics: Aortic Valve; Aortic Valve Stenosis; Calcinosis; Cardiovascular Agents; Endothelial Cells; ERRalpha Estrogen-Related Receptor; Gene Regulatory Networks; Humans; Induced Pluripotent Stem Cells; Machine Learning; Nitriles; Receptor, Notch1; Receptors, Estrogen; Thiazoles

2021