thiazoles has been researched along with carbachol in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (14.29) | 18.7374 |
| 1990's | 11 (26.19) | 18.2507 |
| 2000's | 11 (26.19) | 29.6817 |
| 2010's | 11 (26.19) | 24.3611 |
| 2020's | 3 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Blanchard, JC; Doble, A; Hubert, JP | 1 |
| Ballabeni, V; Barocelli, E; Chiavarini, M; Impicciatore, M; Mingiardi, MR; Morini, G; Ronchini, F | 1 |
| Momose, K; Nobe, K; Ohata, H | 2 |
| Endoh, M; Hirano, K; Norota, I; Satoh, H | 1 |
| Cass, WA; Dunwiddie, TV; Fitzpatrick, FA; Taylor, M; Zahniser, NR | 1 |
| el-Fakahany, EE; Lai, WS | 1 |
| Abraham, WM; Ahmed, A; Garrido, R; Stevenson, JS; Tomioka, K | 1 |
| Fest, W; Söling, HD | 1 |
| Dahlbom, R; Lindeke, B; Ringdahl, B | 1 |
| Ahrén, B; Lundquist, I | 1 |
| Barker, LA | 1 |
| Bito, LZ | 1 |
| Bado, A; Braquet, P; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I; Tarrade, T | 1 |
| Hara, Y; Nakaya, H | 1 |
| Del Río, J; García-Garayoa, E; Lasheras, B; Monge, A; Ramirez, MJ; Roca, J; Romero, G | 1 |
| Arakida, Y; Honda, K; Miyata, K; Ohga, K; Suwa, K; Yamada, T; Yokota, M | 1 |
| Groot, JA; Meijer, HP; Munnik, T; Oprins, JC; van der Burg, C | 1 |
| Hamm-Alvarez, SF; Jerdeva, GV; Kalman, D; Rhodes, CJ; Schechter, JE; Wu, K; Yarber, FA | 1 |
| Khan, I; Oriowo, MA | 1 |
| Maruyama, T; Matsui, T; Miyata, K; Nagase, I; Sasamata, M; Sato, S; Takasu, T; Uchida, H; Ukai, M; Yamaguchi, O | 1 |
| Chatsudthipong, V; Kaewmokul, S; Muanprasat, C | 1 |
| Cusack, B; Dekat, SE; Johnson, JL; Rosenberry, TL; Sonoda, LK | 2 |
| Blanck, TJ; Garavito-Aguilar, ZV; Patel, S; Perez-Castro, R; Recio-Pinto, E; Rosenberg, A; Xu, F; Zhang, J | 1 |
| Costa, LG; Giordano, G; Guizzetti, M; VanDemark, KL | 1 |
| Becker, HC; Griffin, WC; Lopez, MF | 1 |
| Harris, GJ; Howard, JA; Marinkovic, K; O'Reilly, CE; Oscar-Berman, M; Sawyer, K; Urban, T | 1 |
| Auletta, JT; Johnson, JL; Rosenberry, TL | 1 |
| Bachmann, TT; Constantinof, A; Dounin, V; Kerman, K; Schulze, H | 1 |
| Baumgartner, R; Behr-Roussel, D; Giuliano, F; Gorny, D; Ney, P; Oger-Roussel, S; Tasler, S | 1 |
| Andersson, KE; Bouchelouche, K; Bouchelouche, P; Korstanje, C; Nordling, J; Svalø, J | 1 |
| Bartolome, JM; Conn, PJ; Pollard, M; Shaban, H; Steckler, T | 1 |
| Alexandre, EC; Antunes, E; Claudino, MA; Costa, FF; da Silva, FH; de Nucci, G; Fertrin, KY; Franco-Penteado, CF; Leiria, LO; Mónica, FZ; Renno, A | 1 |
| Hirayama, M; Hori, Y; Ito, K; Kawabata, Y; Kawachi, M; Matsunaga, Y; Nagahama, K; Ozaki, T; Shiraishi, Y; Takei, M; Tanaka, T | 1 |
| De Wachter, S; Eastham, J; Gillespie, J; Persyn, S; Wyndaele, JJ | 1 |
| Alexandre, EC; Antunes, E; Calmasini, FB; Candido, TZ; da Silva, CPV; da Silva, FH; de Oliveira, MG; Mónica, FZ | 1 |
| Antunes, E; Bonilla-Becerra, SM; Calmasini, FB; de Oliveira, MG; Rojas-Moscoso, JA; Zanesco, A | 1 |
| Eto, M; Itsumi, M; Kajioka, S; Kareman, E; Lee, K; Maki, T; Shiota, M | 1 |
| Chermansky, C; Ikeda, Y; Kanai, A; Mizoguchi, S; Singh, N; Suzuki, T; Tyagi, P; Yoshimura, N; Zabbarova, I | 1 |
| Hennenberg, M; Huang, R; Stief, CG; Strittmatter, F; Tamalunas, A; Waidelich, R | 1 |
| Chess-Williams, R; McDermott, C; Sellers, DJ; West, EG | 1 |
42 other study(ies) available for thiazoles and carbachol
| Article | Year |
|---|---|
Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on D-[3H]aspartate release from cultured cerebellar granule cells.
Topics: Anesthetics; Aspartic Acid; Carbachol; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Humans; Pertussis Toxin; Riluzole; Thiazoles; Virulence Factors, Bordetella | 1992 |
Pharmacological properties of new 1,2-benzisothiazolyloxypropanolamines on cardiac and tracheal beta-receptors.
Topics: Adrenergic beta-Antagonists; Animals; Carbachol; Heart; Heart Atria; Isoproterenol; Male; Molecular Structure; Myocardium; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Structure-Activity Relationship; Thiazoles; Trachea | 1992 |
Role of phosphatidic acid in carbachol-induced contraction in guinea pig Taenia coli.
Topics: Animals; Biological Transport, Active; Calcium; Carbachol; Colon; Diacylglycerol Kinase; Diglycerides; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Phosphatidic Acids; Phosphotransferases; Pyrimidinones; Thiazoles | 1991 |
Effects of a new 1,3-thiazole derivative ZSY-39 on force of contraction and cyclic AMP content in canine ventricular muscle.
Topics: Animals; Carbachol; Cardiotonic Agents; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Female; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phosphodiesterase Inhibitors; Pyridines; Thiazoles | 1990 |
Arachidonic acid metabolites do not mediate modulation of neurotransmitter release by adenosine in rat hippocampus or striatum.
Topics: Acetophenones; Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Baclofen; Carbachol; Corpus Striatum; Evoked Potentials; Hippocampus; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Neurotransmitter Agents; Phospholipases; Rats; Rats, Inbred Strains; Second Messenger Systems; Thiazoles | 1990 |
Antagonism by the diacylglycerol kinase inhibitor R59 022 of muscarinic receptor-mediated cyclic GMP formation and binding of [3H]N-methylscopolamine.
Topics: Animals; Binding, Competitive; Carbachol; Cyclic GMP; Diacylglycerol Kinase; Mice; Muscarinic Antagonists; N-Methylscopolamine; Phosphotransferases; Pyrimidinones; Receptors, Muscarinic; Scopolamine Derivatives; Thiazoles; Tumor Cells, Cultured | 1990 |
YM461, a PAF antagonist, blocks antigen-induced late airway responses and airway hyperresponsiveness in allergic sheep.
Topics: Aerosols; Animals; Antigens; Ascaris; Carbachol; Dose-Response Relationship, Drug; Platelet Activating Factor; Pyridines; Respiratory Hypersensitivity; Sheep; Thiazoles; Thiazolidines | 1989 |
Synthesis of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) in exocrine glands and its control by secretagogues.
Topics: Acetates; Acetic Acid; Animals; Calcimycin; Carbachol; Ceruletide; Cholecystokinin; Exocrine Glands; Exocytosis; Extracellular Space; Guinea Pigs; Male; Platelet Activating Factor; Platelet Aggregation; Thiazoles; Tissue Distribution | 1986 |
Acetylene compounds of potential pharmacological value. XL. N-(tert-aminoalkynyl)-substituted 3-isothiazolidinone-1,1-dioxides and tetrahydro-1,2-thiazin-3-one-1,1-dioxides.
Topics: Animals; Anticonvulsants; Benzopyrans; Carbachol; Chemical Phenomena; Chemistry; Chromans; Cyclic S-Oxides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Structure-Activity Relationship; Thiazines; Thiazoles | 1987 |
Effects of selective and non-selective beta-adrenergic agents on insulin secretion in vivo.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Isoproterenol; Metoprolol; Mice; Propanolamines; Propranolol; Terbutaline; Thiazoles | 1981 |
Histamine H1- and muscarinic receptor antagonist activity of cimetidine and tiotidine in the guinea pig isolated ileum.
Topics: Animals; Carbachol; Cimetidine; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Thiazoles | 1981 |
Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds.
Topics: Animals; Carbachol; Cats; Dinoprost; Dinoprostone; Epoprostenol; Female; Intraocular Pressure; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins F, Synthetic; Thiazoles; Thiazolidines; Timolol | 1984 |
Platelet-activating factor stimulates gastric acid secretion in isolated rabbit gastric glands.
Topics: Aminopyrine; Animals; Azepines; Biological Transport; Calcium; Carbachol; Dose-Response Relationship, Drug; Egtazic Acid; Famotidine; Fluorescent Dyes; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Rabbits; Thiazoles; Thienopyridines; Triazoles; Verapamil | 1995 |
Activation of diacylglycerol kinase by carbachol in guinea pig taenia coli.
Topics: Animals; Calcium; Carbachol; Colon; Diacylglycerol Kinase; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Phosphatidic Acids; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Pyrimidinones; Thiazoles | 1994 |
SD-3212, a new class I and IV antiarrhythmic drug: a potent inhibitor of the muscarinic acetylcholine-receptor-operated potassium current in guinea-pig atrial cells.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Bepridil; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cells, Cultured; Guinea Pigs; Heart; Heart Atria; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Potassium; Potassium Channels; Sodium; Sodium Channels; Thiazoles | 1995 |
VB20B7, a novel 5-HT-ergic agent with gastrokinetic activity. I. Interaction with 5-HT3 and 5-HT4 receptors.
Topics: Animals; Benzothiazoles; Carbachol; Cyclic AMP; Esophagus; Female; Gastrointestinal Agents; Guinea Pigs; Ileum; In Vitro Techniques; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Thiazoles | 1997 |
In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbachol; Dinoprost; Guinea Pigs; Humans; In Vitro Techniques; Leukotriene Antagonists; Leukotriene D4; Male; Membrane Proteins; Muscle Contraction; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin D2; Receptors, Leukotriene; Receptors, Thromboxane; Tetrazoles; Thiazoles; Trachea | 1998 |
PLD pathway involved in carbachol-induced Cl- secretion: possible role of TNF-alpha.
Topics: 1-Butanol; Adrenergic beta-Antagonists; Carbachol; Carcinogens; Chlorides; Cholinergic Agonists; Chromatography, Thin Layer; Diacylglycerol Kinase; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; HT29 Cells; Humans; Indoles; Intestinal Mucosa; Maleimides; Phorbol Esters; Phospholipase D; Propranolol; Protein Kinase C; Pyrimidinones; Receptors, Muscarinic; Signal Transduction; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells.
Topics: Actin Cytoskeleton; Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Diacetyl; Epithelial Cells; Exocytosis; Eye Proteins; Female; Fluorescence Recovery After Photobleaching; Lacrimal Apparatus; Membrane Proteins; Microscopy, Confocal; Naphthalenes; Nonmuscle Myosin Type IIA; Rabbits; Recombinant Fusion Proteins; Secretory Vesicles; Thiazoles; Thiazolidines | 2005 |
Mechanism underlying the reversal of contractility dysfunction in experimental colitis by cyclooxygenase-2 inhibition.
Topics: Animals; Blotting, Western; Carbachol; Colitis; Colon; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gastrointestinal Motility; Isometric Contraction; Male; Malondialdehyde; Meloxicam; Muscle, Smooth; p38 Mitogen-Activated Protein Kinases; Peroxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiazines; Thiazoles; Trinitrobenzenesulfonic Acid | 2006 |
Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Animals; Carbachol; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Humans; Isoproterenol; Muscle Contraction; Propanolamines; Thiazoles; Urinary Bladder | 2007 |
Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.
Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Animals; Apigenin; Bucladesine; Carbachol; Cell Line, Tumor; Chloride Channels; Cholera Toxin; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Intestines; Jejunum; Luminescent Proteins; Mice; Mice, Inbred ICR; Molecular Structure; Phosphodiesterase Inhibitors; Rats; Sulfonamides; Tetrahydronaphthalenes; Thiazoles | 2007 |
Monitoring the reaction of carbachol with acetylcholinesterase by thioflavin T fluorescence and acetylthiocholine hydrolysis.
Topics: Acetylcholinesterase; Acetylthiocholine; Benzothiazoles; Carbachol; Humans; Hydrolysis; Recombinant Proteins; Spectrometry, Fluorescence; Thiazoles | 2008 |
Analysis of the reaction of carbachol with acetylcholinesterase using thioflavin T as a coupled fluorescence reporter.
Topics: Acetylcholinesterase; Acetylthiocholine; Acylation; Benzothiazoles; Binding Sites; Carbachol; Catalysis; Fluorescent Dyes; Hydrolysis; Kinetics; Ligands; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Thiazoles | 2008 |
Cytotoxicity of local anesthetics in human neuronal cells.
Topics: Anesthetics, Local; Apoptosis; Calcium; Carbachol; Caspases; Cell Line, Tumor; Cell Survival; Colorimetry; Enzyme Activation; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Muscarinic Agonists; Neurons; Potassium Channel Blockers; Tetraethylammonium; Tetrazolium Salts; Tetrodotoxin; Thiazoles | 2009 |
Ethanol inhibits muscarinic receptor-induced axonal growth in rat hippocampal neurons.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Central Nervous System Depressants; Coloring Agents; Culture Media, Conditioned; Ethanol; Female; Hippocampus; Immunohistochemistry; Muscarinic Agonists; Neurites; Neurons; Parasympathetic Nervous System; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Tetrazolium Salts; Thiazoles | 2009 |
Intensity and duration of chronic ethanol exposure is critical for subsequent escalation of voluntary ethanol drinking in mice.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Carbachol; Cells, Cultured; Central Nervous System Depressants; Coloring Agents; Culture Media, Conditioned; Ethanol; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Immunohistochemistry; Male; Mice; Muscarinic Agonists; Neurons; Pregnancy; Protein Kinase C; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazolium Salts; Thiazoles | 2009 |
Alcoholism and dampened temporal limbic activation to emotional faces.
Topics: Animals; Astrocytes; Axons; Blotting, Western; Carbachol; Cells, Cultured; Central Nervous System Depressants; Culture Media, Conditioned; Ethanol; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Immunohistochemistry; Muscarinic Agonists; Neurons; Pregnancy; Protein Kinase C; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetrazolium Salts; Thiazoles | 2009 |
Molecular basis of inhibition of substrate hydrolysis by a ligand bound to the peripheral site of acetylcholinesterase.
Topics: Acetylcholinesterase; Acetylthiocholine; Animals; Benzothiazoles; Binding, Competitive; Carbachol; Catalytic Domain; Cell Line; Cholinesterase Inhibitors; Crystallography, X-Ray; Humans; Hydrolysis; Kinetics; Ligands; Quaternary Ammonium Compounds; Substrate Specificity; Thiazoles | 2010 |
Electrochemical detection of interaction between Thioflavin T and acetylcholinesterase.
Topics: Acetylcholinesterase; Benzothiazoles; Binding Sites; Carbachol; Cholinesterase Inhibitors; Electrochemical Techniques; Electrodes; Oxidation-Reduction; Paraoxon; Spectrometry, Fluorescence; Thiazoles | 2011 |
An aryloxypropanolamine hβ3-adrenoceptor agonist as bladder smooth muscle relaxant.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Aged; Aniline Compounds; Benzoates; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Ligands; Male; Muscle Relaxation; Muscle, Smooth; Propanolamines; Receptors, Adrenergic, beta-3; Thiazoles; Urinary Bladder | 2012 |
The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Carbachol; Humans; In Vitro Techniques; Inhibitory Concentration 50; Isoproterenol; Male; Middle Aged; Muscle Contraction; Thiazoles; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder, Overactive | 2013 |
Modulation of neuronal microcircuit activities within the medial prefrontal cortex by mGluR5 positive allosteric modulator.
Topics: Action Potentials; Allosteric Regulation; Animals; Benzamides; Carbachol; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Neural Pathways; Prefrontal Cortex; Pyrazoles; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2014 |
Urinary Bladder Dysfunction in Transgenic Sickle Cell Disease Mice.
Topics: Acetanilides; Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Atropine; Calcium Chloride; Carbachol; Disease Models, Animal; Diuresis; Electric Stimulation; Hemoglobin, Sickle; Humans; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Contraction; Muscle, Smooth; Phenylephrine; Potassium Chloride; Thiazoles; Urethra; Urinary Bladder | 2015 |
Acotiamide Hydrochloride, a Therapeutic Agent for Functional Dyspepsia, Enhances Acetylcholine-induced Contraction via Inhibition of Acetylcholinesterase Activity in Circular Muscle Strips of Guinea Pig Stomach.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Benzamides; Benzyl Compounds; Carbachol; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Dyspepsia; Guinea Pigs; In Vitro Techniques; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Neostigmine; Stomach; Thiazoles | 2016 |
The actions of isoprenaline and mirabegron in the isolated whole rat and guinea pig bladder.
Topics: Acetanilides; Animals; Arecoline; Carbachol; Female; Guinea Pigs; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Muscle Contraction; Rats, Sprague-Dawley; Thiazoles; Urinary Bladder | 2016 |
Long-term treatment with the beta-3 adrenoceptor agonist, mirabegron ameliorates detrusor overactivity and restores cyclic adenosine monophosphate (cAMP) levels in obese mice.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Animals; Body Weight; Carbachol; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Muscle Contraction; Muscle, Smooth; Obesity; Thiazoles; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2017 |
Micturition dysfunction in four-month old ovariectomized rats: Effects of testosterone replacement.
Topics: Acetanilides; Androgens; Angiotensin II; Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Letrozole; Muscle, Smooth; Nitriles; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Testosterone; Thiazoles; Triazoles; Urethra; Urination Disorders | 2017 |
Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle.
Topics: Acetanilides; Adenylyl Cyclase Inhibitors; Aged; Amides; Animals; Carbachol; Cyclic AMP; Female; Humans; Indoles; Isoquinolines; Male; Maleimides; Muscle Relaxation; Muscle, Smooth; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; rho-Associated Kinases; Signal Transduction; Sulfonamides; Swine; Thiazoles; Urinary Bladder; Urological Agents | 2019 |
Excitatory effect of acotiamide on rat and human bladder: Implications for underactive bladder treatment.
Topics: Animals; Benzamides; Carbachol; Electric Stimulation; Humans; Male; Muscle Contraction; Rats, Sprague-Dawley; Thiazoles; Urinary Bladder; Urinary Bladder, Underactive | 2020 |
Inhibition of Full Smooth Muscle Contraction in Isolated Human Detrusor Tissues by Mirabegron Is Limited to Off-Target Inhibition of Neurogenic Contractions.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetanilides; Carbachol; Endothelin-1; Female; Humans; Male; Methacholine Chloride; Muscle Contraction; Muscle, Smooth; Receptors, Adrenergic; Thiazoles; Urinary Bladder, Overactive | 2022 |
Mirabegron and solifenacin are effective for the management of the increased urinary frequency induced by psychological stress in female mice.
Topics: Acetanilides; Animals; Carbachol; Female; Mice; Muscarinic Antagonists; Solifenacin Succinate; Stress, Psychological; Thiazoles; Treatment Outcome; Urinary Bladder, Overactive | 2022 |