Compounds > thiazoles
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thiazoles and bal 30072

thiazoles has been researched along with bal 30072 in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's17 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dantier, C; Desarbre, E; Page, MG1
Bajaksouzian, S; Beanan, JM; Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Jacobs, M; Olson, R; Page, MG; Russo, TA1
Desarbre, E; Kvitko, BH; Mima, T; Page, MG; Rholl, DA; Schweizer, HP1
Schmitz, J1
Hackel, M; Higgins, PG; Page, MG; Seifert, H; Stefanik, D1
Dantier, C; Desarbre, E; Gebhardt, K; Hofer, B; Page, MG; Schmitt-Hoffmann, A1
Köhler, T; Page, MG; van Delden, C1
Adkin, R; Hope, R; Livermore, DM; Mushtaq, S; Woodford, N1
Hornsey, M; Phee, L; Stubbings, W; Wareham, DW1
El-Imad, B; Landman, D; Miller, E; Quale, J; Singh, M; Win, T1
Bi, CW; Fu, HG; Hu, XX; Jiang, JD; Li, CR; Li, YH; Song, DQ; Tang, S; Wang, YX; You, XF1
Blenk, H; Naber, KG; Straubinger, M; Wagenlehner, FM1
Braun, Y; Köhler, T; Luscher, A; Moynié, L; Naismith, JH; Page, MG; Pletzer, D; Rolo, D; Tortajada, A; Weingart, H1
Chen, Q; Chen, X; Chu, W; Kou, Q; Niu, A; Tan, L; Tao, Y; Wang, H; Wang, T; Yang, Y; Zhang, S; Zou, F1
Church, RJ; Engelhardt, M; Howell, BA; Krähenbühl, S; Maurer, M; Messner, S; Paech, F; Schmitt-Hoffmann, AH; Spickermann, J; Wind, M; Witschi, AT; Woodhead, J1
Auguste, PS; Bumann, D; Köhler, T; Luscher, A; Mazza, L; Moynié, L; Naismith, JH; Pletzer, D1
Ceccarelli, M; Desarbre, E; Malloci, G; Milenkovic, S; Moynié, L; Naismith, JH; Page, MGP; Scorciapino, MA; Serra, I1

Trials

2 trial(s) available for thiazoles and bal 30072

ArticleYear
Urinary Concentrations and Antibacterial Activity of BAL30072, a Novel Siderophore Monosulfactam, against Uropathogens after Intravenous Administration in Healthy Subjects.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6

    Topics: Administration, Intravenous; Adult; Anti-Bacterial Agents; Chromatography, Liquid; Enterobacteriaceae; Escherichia coli; Healthy Volunteers; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Monobactams; Proteus mirabilis; Tandem Mass Spectrometry; Thiazoles; Urinary Tract Infections

2016
Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072.
    Archives of toxicology, 2017, Volume: 91, Issue:11

    Topics: Adenosine Triphosphate; Apoptosis; Cell Survival; Chemical and Drug Induced Liver Injury; Electron Transport; Glycolysis; Hep G2 Cells; Hepatocytes; Humans; Kupffer Cells; Lipopolysaccharides; Liver-Specific Organic Anion Transporter 1; Male; Microsomes, Liver; Monobactams; Solute Carrier Organic Anion Transporter Family Member 1B3; Thiazoles

2017

Other Studies

15 other study(ies) available for thiazoles and bal 30072

ArticleYear
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Monobactams; Mutation; Penicillin-Binding Proteins; Phenotype; Pseudomonas aeruginosa; Siderophores; Thiazoles

2010
In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2011, Volume: 66, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Interactions; Meropenem; Microbial Sensitivity Tests; Monobactams; Rats; Rodent Diseases; Siderophores; Thiazoles; Thienamycins; Treatment Outcome

2011
In vitro activity of BAL30072 against Burkholderia pseudomallei.
    International journal of antimicrobial agents, 2011, Volume: 38, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactamases; Biological Transport; Burkholderia pseudomallei; Environmental Microbiology; Humans; Melioidosis; Microbial Sensitivity Tests; Microbial Viability; Monobactams; Thailand; Thiazoles; Time Factors

2011
[BAL30072--an iron complexing beta lactam antibiotic against multidrug-resistant gram negative bacteria].
    Pharmazie in unserer Zeit, 2011, Volume: 40, Issue:2

    Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Monobactams; Thiazoles

2011
In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:5

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Gene Expression; Humans; Meropenem; Microbial Sensitivity Tests; Monobactams; Thiazoles; Thienamycins

2012
Combined effects of the siderophore monosulfactam BAL30072 and carbapenems on multidrug-resistant Gram-negative bacilli.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:5

    Topics: Acinetobacter; Anti-Bacterial Agents; Carbapenems; Doripenem; Drug Resistance, Multiple, Bacterial; Drug Synergism; Enterobacteriaceae; Imipenem; Meropenem; Microbial Sensitivity Tests; Microbial Viability; Monobactams; Pseudomonas aeruginosa; Thiazoles; Thienamycins

2013
Involvement of Fe uptake systems and AmpC β-lactamase in susceptibility to the siderophore monosulfactam BAL30072 in Pseudomonas aeruginosa.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:5

    Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Ceftazidime; Drug Resistance, Multiple, Bacterial; Gene Expression Regulation, Bacterial; Ion Transport; Iron; Iron Deficiencies; Microbial Sensitivity Tests; Monobactams; Mutation; Operon; Phenols; Pseudomonas aeruginosa; Siderophores; Sigma Factor; Thiazoles

2013
Activity of BAL30072 alone or combined with β-lactamase inhibitors or with meropenem against carbapenem-resistant Enterobacteriaceae and non-fermenters.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; DNA, Bacterial; Drug Synergism; Enterobacteriaceae; Enterobacteriaceae Infections; Enzyme Inhibitors; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Monobactams; Polymerase Chain Reaction; Sequence Analysis, DNA; Thiazoles; Thienamycins; United Kingdom

2013
In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens.
    International journal of antimicrobial agents, 2013, Volume: 42, Issue:4

    Topics: Anti-Bacterial Agents; Drug Synergism; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Meropenem; Microbial Sensitivity Tests; Monobactams; Thiazoles; Thienamycins

2013
In vitro activity of the siderophore monosulfactam BAL30072 against contemporary Gram-negative pathogens from New York City, including multidrug-resistant isolates.
    International journal of antimicrobial agents, 2014, Volume: 43, Issue:6

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Gram-Negative Bacterial Infections; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monobactams; New York City; Pseudomonas aeruginosa; Thiazoles

2014
Design, synthesis and biological evaluation of monobactams as antibacterial agents against gram-negative bacteria.
    European journal of medicinal chemistry, 2016, Mar-03, Volume: 110

    Topics: Anti-Bacterial Agents; Aztreonam; Drug Design; Escherichia coli; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Monobactams; Structure-Activity Relationship; Thiazoles

2016
Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:4

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Microbial Sensitivity Tests; Monobactams; Mutation; Pseudomonas aeruginosa; Thiazoles

2017
Discovery of Novel Pyridone-Conjugated Monosulfactams as Potent and Broad-Spectrum Antibiotics for Multidrug-Resistant Gram-Negative Infections.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Drug Discovery; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Mice; Microbial Sensitivity Tests; Monobactams; Pyridones; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazoles

2017
TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:6

    Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Biological Transport; Carrier Proteins; Cefiderocol; Cell Membrane Permeability; Cephalosporins; Membrane Proteins; Monobactams; Pseudomonas aeruginosa; Siderophores; Thiazoles

2018
Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2019, Volume: 32, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Microbial Sensitivity Tests; Molecular Conformation; Molecular Docking Simulation; Monobactams; Pseudomonas aeruginosa; Siderophores; Thiazoles

2019