Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and as 601245

thiazoles has been researched along with as 601245 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carboni, S; Gaillard, P; Gotteland, JP; Hiver, A; Szyndralewiez, C; Vitte, PA1
Ballerio, R; Carboni, S; Cirillo, R; Ferrandi, C; Gaillard, P; Giachetti, C; Gotteland, JP; Vitte, PA1
Antonsson, B; Carboni, S; Gaillard, P; Gillon, JY; Gotteland, JP; Vitte, PA1
Ardissone, V; Arkinstall, S; Cambet, Y; Camps, M; Chabert, C; Church, D; Cirillo, R; Gaillard, P; Gotteland, JP; Gretener, D; Halazy, S; Jeanclaude-Etter, I; Nichols, A; Szyndralewiez, C; Vitte, PA1
Zhang, GY; Zhang, QG1

Reviews

1 review(s) available for thiazoles and as 601245

ArticleYear
Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:11

    Topics: Acetonitriles; Animals; Anthracenes; Apoptosis; Benzothiazoles; Carbazoles; Humans; Indole Alkaloids; Indoles; JNK Mitogen-Activated Protein Kinases; Neuroprotective Agents; Protein Kinase Inhibitors; Signal Transduction; Thiazoles

2005

Other Studies

4 other study(ies) available for thiazoles and as 601245

ArticleYear
AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: Acetonitriles; Animals; Benzothiazoles; Brain Ischemia; Disease Models, Animal; Gerbillinae; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinases; Neuroprotective Agents; Phosphorylation; Rats; Rats, Wistar; Thiazoles; Tumor Necrosis Factor-alpha

2004
Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats.
    British journal of pharmacology, 2004, Volume: 142, Issue:6

    Topics: Acetonitriles; Anesthesia; Animals; Apoptosis; Benzothiazoles; Blood Pressure; Blotting, Western; Coronary Disease; DNA Fragmentation; Enzyme Activation; Heart Rate; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Thiazoles

2004
Control of death receptor and mitochondrial-dependent apoptosis by c-Jun N-terminal kinase in hippocampal CA1 neurones following global transient ischaemia.
    Journal of neurochemistry, 2005, Volume: 92, Issue:5

    Topics: Acetonitriles; Analysis of Variance; Animals; Apoptosis; Benzothiazoles; Caspases; Cytochromes c; Enzyme Activation; Gerbillinae; Hippocampus; In Situ Nick-End Labeling; Ischemic Attack, Transient; JNK Mitogen-Activated Protein Kinases; Male; Mitochondria; Neurons; Reperfusion Injury; Thiazoles; Time Factors

2005
Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase.
    Journal of medicinal chemistry, 2005, Jul-14, Volume: 48, Issue:14

    Topics: Acetonitriles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Experimental; Benzothiazoles; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Rats; Structure-Activity Relationship; Thiazoles; Tumor Necrosis Factor-alpha

2005