thiazoles has been researched along with alvocidib in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blagosklonny, MV | 1 |
| Carlson, P; Grant, S; Krystal, GW; Litz, J; Warshamana-Greene, GS | 1 |
| Cress, WD; Freeman, SN; Ma, Y | 1 |
| Bosco, MC; Melillo, G; Pastorino, S; Pezzolo, A; Puppo, M; Varesio, L | 1 |
| Blagden, S; de Bono, J | 1 |
| Chen, R; Chubb, S; Fox, JA; Gandhi, V; Hawtin, RE; Keating, MJ; Plunkett, W; Wierda, WG | 1 |
| Bantscheff, M; Drewes, G; Eberhard, D; Frenzel, L; Ghidelli, S; Kruse, U; Maier, SK; Pallasch, CP; Wendtner, CM; Werner, T | 1 |
| Ceckova, M; Cihalova, D; Staud, F | 1 |
| Giordano, A; Morales, F | 1 |
| Adamo, ME; Cheng, C; Kettenbach, AN; Petrone, A | 1 |
2 review(s) available for thiazoles and alvocidib
| Article | Year |
|---|---|
Drugging cell cycle kinases in cancer therapy.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Binding Sites; Cyclin-Dependent Kinases; Flavonoids; Humans; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Roscovitine; Staurosporine; Sulfonamides; Thiazoles | 2005 |
Overview of CDK9 as a target in cancer research.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Cycle; Cyclic N-Oxides; Cyclin-Dependent Kinase 9; Flavonoids; Humans; Indolizines; Molecular Targeted Therapy; Neoplasms; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyridinium Compounds; Roscovitine; Thiazoles; Urea | 2016 |
8 other study(ies) available for thiazoles and alvocidib
| Article | Year |
|---|---|
Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Cyclosporins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epothilones; Epoxy Compounds; Flavonoids; Hematopoietic Stem Cells; HL-60 Cells; Humans; Jurkat Cells; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Oligopeptides; Paclitaxel; Piperidines; Poly(ADP-ribose) Polymerases; Pyrazines; Substrate Specificity; Thiazoles | 2001 |
Flavopiridol potently induces small cell lung cancer apoptosis during S phase in a manner that involves early mitochondrial dysfunction.
Topics: Aphidicolin; Apoptosis; Blotting, Western; Carcinoma, Small Cell; Caspase 3; Caspases; Cell Division; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Membrane Potentials; Mitochondria; Piperidines; Poly(ADP-ribose) Polymerases; S Phase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2003 |
E2F4 deficiency promotes drug-induced apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F4 Transcription Factor; Fibroblasts; Flavonoids; Humans; Lung Neoplasms; Mice; Mice, Knockout; Oxazoles; Piperidines; Protein Kinase Inhibitors; Purines; RNA, Small Interfering; Roscovitine; Thiazoles; Transcription Factors; Tumor Cells, Cultured | 2004 |
Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation.
Topics: Apoptosis; Bromodeoxyuridine; Caspases; Cell Hypoxia; Cell Survival; Cyclin-Dependent Kinases; Cytochromes c; DNA; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; G1 Phase; G2 Phase; Genes, myc; Growth Inhibitors; Humans; Hypoxia; In Situ Nick-End Labeling; Neuroblastoma; Piperidines; Proto-Oncogene Mas; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2004 |
Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia.
Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Caspases; Cyclin-Dependent Kinases; Female; Flavonoids; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Membrane Potential, Mitochondrial; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Oxazoles; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Thiazoles; Transcription, Genetic; X-Linked Inhibitor of Apoptosis Protein | 2009 |
Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells.
Topics: Apoptosis; Flavonoids; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Oxazoles; Piperidines; Positive Transcriptional Elongation Factor B; Protein Kinase Inhibitors; Proteomics; Thiazoles | 2011 |
Interactions of cyclin-dependent kinase inhibitors AT-7519, flavopiridol and SNS-032 with ABCB1, ABCG2 and ABCC1 transporters and their potential to overcome multidrug resistance in vitro.
Topics: Animals; ATP-Binding Cassette Transporters; Cell Proliferation; Dogs; Drug Interactions; Drug Resistance, Multiple; Flavonoids; Humans; Madin Darby Canine Kidney Cells; Oxazoles; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Thiazoles | 2015 |
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics.
Topics: CDC2 Protein Kinase; Chromatography, Liquid; Cyclin-Dependent Kinases; Flavonoids; Gene Expression Regulation; HeLa Cells; Humans; Mitosis; Phosphoproteins; Piperidines; Protein Interaction Maps; Proteomics; Quinolines; Signal Transduction; Small Molecule Libraries; Tandem Mass Spectrometry; Thiazoles | 2016 |