thiazoles has been researched along with alpha-chymotrypsin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (31.82) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Conquet, P; Gautheron, P; Schmitt, C; Share, NN; Smith, RL; Stone, CA; Sugrue, MF; Viader, MP | 1 |
| Coletti-Previero, MA; Kraicsovits, F; Previero, A | 1 |
| Glimcher, MJ; Shuttleworth, A | 1 |
| Bogulska, M; Katzenellenbogen, E; Lugowski, C; Romanowska, E | 1 |
| Barfknecht, CF; Eller, MG; Lewis, RA; Phelps, CD; Schoenwald, RD | 1 |
| Ashe, BM; Frankshun, R; Jones, H; Morman, H; Mulvey, D; Zimmerman, M | 1 |
| Ashe, BM; Clark, RL; Jones, H; Zimmerman, M | 1 |
| Boggetto, N; Delarge, J; Masereel, B; Pirotte, B; Reboud-Ravaux, M; Schynts, M; Vergely, I; Vilain, AC | 1 |
| Ambler, J; Baettig, U; Brown, L; Brundish, D; Cockcroft, X; Dell, C; Furzer, A; Garman, S; Janus, D; Kane, PD; Mitchelson, A; Smith, G; Talbot, MD; Tweed, M; Walker, CV; Wills, N | 1 |
| Allen, M; Ambler, J; Butler, K; Cockcroft, X; Dunnet, K; Hayler, J; Kane, PD; LeGrand, D; Lugrin, F; Menear, K; Mitchelson, A; Price, R; Talbot, M; Tweed, M; Wills, N | 1 |
| Chong, LS; Epp, JB; Fu, Q; Groutas, WC; He, S; Kuang, R; Li, YH; Ruan, S; Truong, TM; Tu, J; Venkataraman, R; Vu, NT; Yu, H | 1 |
| Gordon, DJ; Meredith, SC; Sciarretta, KL | 1 |
| Bruce-Keller, AJ; Davies, LM; Dimayuga, FO; Keller, JN; Reed, JL | 1 |
| Avilés, FX; Pallarès, I; Vendrell, J; Ventura, S | 1 |
| Klegeris, A; McGeer, PL | 1 |
| Chen, D; Diez, A; Dou, QP; Fregona, D; Giovagnini, L; Milacic, V | 1 |
| Anderson, KC; Aujay, M; Azab, AK; Azab, F; Demo, S; Ghobrial, IM; Maiso, P; Ngo, HT; Quang, P; Roccaro, AM; Runnels, J; Sacco, A | 1 |
| Jin, K; Li, X; Yin, Z; Yu, G | 1 |
| Arduino, DM; Cardoso, SM; Esteves, AR; Januario, C; Martins-Branco, D; Oliveira, CR; Santos, D; Swerdlow, RH | 1 |
| Bilkova, Z; Hromadkova, L; Jankovicova, B; Kupcik, R; Ripova, D; Rousar, T | 1 |
| Hemmateenejad, B; Khoshaman, K; Masoudi, R; Yousefi, R; Zm, SZ | 1 |
| Avery, VM; Calcott, MJ; Carroll, AR; Ekins, MG; Holland, DC; Kaemmerer, E; Schroder, WA | 1 |
22 other study(ies) available for thiazoles and alpha-chymotrypsin
| Article | Year |
|---|---|
On the pharmacology of L-645,151: a topically effective ocular hypotensive carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Benzothiazoles; Carbonic Anhydrase Inhibitors; Chymotrypsin; Diuretics; Dogs; Eye; Female; Intraocular Pressure; Male; Rabbits; Suspensions; Thiadiazoles; Thiazoles; Tissue Distribution | 1985 |
Stereospecificity of alpha-chymotrypsin. Changes of substrate configuration during enzymatic hydrolysis.
Topics: Benzyl Compounds; Carboxylic Acids; Chymotrypsin; Hydrolysis; Indoles; Kinetics; Molecular Conformation; Optical Rotation; Pyridines; Spectrophotometry; Structure-Activity Relationship; Thiazoles | 1973 |
The time-dependent solubility of cyanogen bromide- and chymotrypsin-treated collagen gels in vitro.
Topics: Aldehydes; Amino Acids; Animals; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chymotrypsin; Collagen; Cyanides; Electrophoresis; Hydrogen-Ion Concentration; Hydroxyproline; Light; Peptides; Protein Denaturation; Rats; Rotation; Skin; Solubility; Spectrophotometry; Temperature; Thiazoles; Time Factors | 1970 |
Interaction of Wratizolin with serum albumins and its antiproteolytic activity.
Topics: Animals; Cattle; Chromatography, Gel; Chymotrypsin; Dansyl Compounds; Horses; Humans; In Vitro Techniques; Indomethacin; Ovalbumin; Protease Inhibitors; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Thiazoles; Trypsin Inhibitors; Tryptophan; Uric Acid | 1983 |
Ethoxzolamide analogue gel. A topical carbonic anhydrase inhibitor.
Topics: Animals; Benzothiazoles; Carbonic Anhydrase Inhibitors; Chymotrypsin; Ethoxzolamide; Gels; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Suspensions; Thiazoles | 1984 |
Inhibition of elastase and other serine proteases by heterocyclic acylating agents.
Topics: Animals; Binding Sites; Cathepsins; Chymotrypsin; Humans; Kinetics; Leukocytes; Pancreas; Pancreatic Elastase; Protease Inhibitors; Protein Binding; Saccharin; Serine; Structure-Activity Relationship; Swine; Thiazoles; Trypsin Inhibitors | 1980 |
Selective inhibition of human leukocyte elastase and bovine alpha-chymotrypsin by novel heterocycles.
Topics: Animals; Cathepsin G; Cathepsins; Cattle; Chymotrypsin; Humans; Kinetics; Leukocytes; Pancreatic Elastase; Serine Endopeptidases; Structure-Activity Relationship; Swine; Thiazoles | 1981 |
Evaluation of the inhibitory activity on serine and aspartic proteases of 4-amino-4H-1,2,4-triazole and 5-aminothiazole derivatives structurally related to beta-lactam antibiotics.
Topics: Amino Acid Sequence; Amitrole; Animals; Anti-Bacterial Agents; Aspartic Acid Endopeptidases; beta-Lactams; Cattle; Chymotrypsin; Humans; Leukocyte Elastase; Molecular Sequence Data; Pancreatic Elastase; Pepsin A; Serine Proteinase Inhibitors; Structure-Activity Relationship; Substrate Specificity; Swine; Thiazoles; Thrombin; Trypsin Inhibitors | 1993 |
The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position.
Topics: Alanine; Antithrombins; Arginine; Chymotrypsin; Drug Design; Factor Xa Inhibitors; Fibrinolysin; Kallikreins; Models, Molecular; Molecular Structure; Pipecolic Acids; Serine Proteinase Inhibitors; Structure-Activity Relationship; Sulfonamides; Thiazoles; Thrombin; Trypsin | 2000 |
The design and synthesis of thrombin inhibitors: the introduction of in vivo efficacy and oral bioavailability into benzthiazolylalanine inhibitors.
Topics: Administration, Oral; Alanine; Animals; Antithrombins; Biological Availability; Chymotrypsin; Drug Design; Fibrinolysin; Kinetics; Molecular Conformation; Molecular Structure; Partial Thromboplastin Time; Structure-Activity Relationship; Sulfonamides; Thiazoles; Thrombosis; Trypsin | 2000 |
1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteases.
Topics: Cathepsin G; Cathepsins; Chymotrypsin; Cyclic S-Oxides; Humans; Kinetics; Leukocyte Elastase; Models, Chemical; Molecular Probes; Myeloblastin; Protein Binding; Serine Endopeptidases; Temperature; Thiazoles; Time Factors | 2001 |
Inhibition of beta-amyloid(40) fibrillogenesis and disassembly of beta-amyloid(40) fibrils by short beta-amyloid congeners containing N-methyl amino acids at alternate residues.
Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Benzothiazoles; Chymotrypsin; Drug Resistance; Humans; Methylation; Microscopy, Fluorescence; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Thiazoles; Ultracentrifugation | 2001 |
Estrogen increases proteasome activity in murine microglial cells.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Cell Line; Chymotrypsin; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Estradiol; Estrogens; Interferon-gamma; Leupeptins; Mice; Microglia; Protease Inhibitors; Proteasome Endopeptidase Complex; Receptors, Estradiol; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.
Topics: Amyloid; Benzothiazoles; Chymotrypsin; Circular Dichroism; Congo Red; Fluorescent Dyes; Protein Structure, Secondary; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thiazoles; Trifluoroethanol | 2004 |
Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity.
Topics: Cell Line; Cell Survival; Cells, Cultured; Chymotrypsin; Humans; Hydrogen Peroxide; Interferon-gamma; L-Lactate Dehydrogenase; Microglia; Monocytes; Neurotoxicity Syndromes; Serine Proteinase Inhibitors; Stimulation, Chemical; Subcellular Fractions; Temporal Lobe; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2005 |
Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity.
Topics: Animals; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Calpain; Caspase 3; Cell Line, Tumor; Chymotrypsin; Copper; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Situ Nick-End Labeling; Kinetics; Proteasome Inhibitors; Pyrrolidines; Rabbits; Tetrazolium Salts; Thiazoles; Thiocarbamates; Time Factors; Zinc | 2008 |
Selective inhibition of chymotrypsin-like activity of the immunoproteasome and constitutive proteasome in Waldenstrom macroglobulinemia.
Topics: Apoptosis; Chymotrypsin; Dipeptides; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunoblotting; Insulin-Like Growth Factor I; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lymphoma; NF-kappa B; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Waldenstrom Macroglobulinemia | 2010 |
Hyaluronic acid L-cysteine conjugate exhibits controlled-release potential for mucoadhesive drug delivery.
Topics: Animals; Cell Line; Cell Membrane Permeability; Cell Survival; Chymotrypsin; Coloring Agents; Cysteine; Delayed-Action Preparations; Dogs; Drug Delivery Systems; Excipients; Hyaluronic Acid; Intestines; Mucous Membrane; Protease Inhibitors; Sulfhydryl Compounds; Tetrazolium Salts; Thiazoles; Tissue Adhesives; Trypsin Inhibitors | 2012 |
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Case-Control Studies; Cell Line, Tumor; Cell Proliferation; Chymotrypsin; Citrate (si)-Synthase; Electron Transport Complex I; Female; Green Fluorescent Proteins; Humans; Immunoprecipitation; Lactic Acid; Leukocytes, Mononuclear; Male; Middle Aged; Mitochondria; Neuroblastoma; Parkinson Disease; Plasma; Proteasome Endopeptidase Complex; RNA, Small Interfering; Statistics as Topic; Tetrazolium Salts; Thiazoles; Transfection; Ubiquitin; Ubiquitination; Up-Regulation | 2012 |
Difficulties associated with the structural analysis of proteins susceptible to form aggregates: The case of Tau protein as a biomarker of Alzheimer's disease.
Topics: Adhesiveness; Adsorption; Alzheimer Disease; Amino Acid Motifs; Antibodies, Monoclonal; Benzothiazoles; Biomarkers; Chymotrypsin; Epitopes; Humans; Magnetics; Mass Spectrometry; Proteolysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; tau Proteins; Thiazoles; Trypsin | 2016 |
The structural alteration and aggregation propensity of glycated lens crystallins in the presence of calcium: Importance of lens calcium homeostasis in development of diabetic cataracts.
Topics: Animals; Benzothiazoles; Calcium; Cataract; Cattle; Chymotrypsin; Circular Dichroism; Cross-Linking Reagents; Crystallins; Diabetes Mellitus; Dynamic Light Scattering; Fluorescence; Glycosylation; Homeostasis; Ions; Kinetics; Lens, Crystalline; Molecular Weight; Protein Aggregates; Protein Conformation; Protein Stability; Proteolysis; Thiazoles; Tryptophan | 2017 |
Cyclotheonellazoles D-I, Potent Elastase Inhibitory Thiazole-Containing Cyclic Peptides from
Topics: Amino Acids; Animals; Australia; Chymotrypsin; COVID-19; Humans; Mammals; Molecular Structure; Pancreatic Elastase; Peptides; Peptides, Cyclic; SARS-CoV-2; Theonella; Thiazoles | 2023 |