thiazoles has been researched along with adamantane in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 13 (59.09) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Roos-Verhey, WS; Vos, O | 1 |
| Dressman, JB; Efthymiopoulos, C; Galia, E; Nicolaides, E; Reppas, C | 1 |
| Dressman, JB; Nicolaides, E; Reppas, C; Symillides, M | 1 |
| Bartberger, MD; Castro, VM; Chen, M; Emery, M; Fotsch, C; Gustafsson, S; Hale, C; Hickman, D; Homan, E; Johansson, L; Jordan, SR; Komorowski, R; Li, A; Matsumoto, G; McRae, K; Moniz, G; Orihuela, C; Palm, G; Veniant, M; Wang, M; Williams, M; Zhang, J | 1 |
| Clay, WC; Dean, DK; Michel, AD; Ng, SW; Roman, S; Walter, DS | 1 |
| Uesugi, M | 1 |
| Antoon, JW; Beckman, BS; Burow, ME; Driver, JL; White, MD | 1 |
| Boyd, S; deSchoolmeester, J; Dossetter, AG; Goldberg, FW; Groombridge, SD; Gutierrez, PM; Kemmitt, PD; Robb, GR; Scott, JS; Sjögren, T; Swales, JG; Turnbull, AV; Wild, MJ | 1 |
| Cho, SW; Dal Nam, K; Hahn, HG; Je Lee, W; Kim, EA; Yang, SJ; Young Choi, S | 1 |
| Ahn, JY; Cho, SW; Choi, J; Choi, SY; Han, AR; Kim, EA | 1 |
| Cascioferro, S; Daidone, G; Maggio, B; Raffa, D; Raimondi, MV; Schillaci, D | 1 |
| Ahn, JY; Cho, CH; Cho, SW; Hahn, HG; Kim, J | 1 |
| Warren, RB; Yiu, ZZ | 1 |
| McNaughton, M; Pitman, M; Pitson, SM; Pyne, NJ; Pyne, S | 1 |
| Cho, CH; Cho, SW; Choi, SY; Kim, EA; Kim, J; Yang, SJ | 1 |
| Cho, CH; Cho, SW; Choi, SY; Hahn, HG; Kim, J | 1 |
| Hahm, B; Seo, YJ; Studstill, CJ; Vijayan, M; Wolf, JJ; Xia, C | 1 |
| Adhikari, A; Shen, B; Teijaro, CN | 1 |
| Qi, L; Wang, R; Yu, HZ | 1 |
| Cho, SW; Choi, HR; Choi, SY; Han, AR; Hwang, K; Kim, EA; Yang, SJ | 1 |
| Baumgart, S; Bilski, R; Kołodziejska, R; Kupczyk, D; Paprocka, R; Płaziński, W; Studzińska, R | 1 |
| Abdelbaky, MSM; El-Ashmawy, MB; El-Emam, AA; Garcia-Granda, S; Habib, EE; Thamotharan, S; Warda, ET | 1 |
3 review(s) available for thiazoles and adamantane
| Article | Year |
|---|---|
[Control and analysis of cells by synthetic small molecules].
Topics: Adamantane; Animals; Benzopyrans; Cell- and Tissue-Based Therapy; Combinatorial Chemistry Techniques; Humans; Indoles; Intercellular Signaling Peptides and Proteins; Molecular Biology; Molecular Conformation; Molecular Weight; Piperazines; Pyridines; Signal Transduction; Sulfonamides; Thiazoles; Transcription, Genetic | 2012 |
Novel Oral Therapies for Psoriasis and Psoriatic Arthritis.
Topics: Adamantane; Adenosine; Adenosine A3 Receptor Antagonists; Administration, Oral; Arthritis, Psoriatic; Azetidines; Biological Factors; Biological Therapy; Clinical Trials as Topic; Humans; Isonicotinic Acids; Janus Kinases; Niacinamide; Phosphodiesterase 4 Inhibitors; Piperidines; Protein Kinase Inhibitors; Psoriasis; Purines; Pyrazoles; Pyrimidines; Pyrroles; Receptors, Lysosphingolipid; rho-Associated Kinases; Sulfonamides; Thalidomide; Thiazoles | 2016 |
Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts.
Topics: Adamantane; Aminobenzoates; Aminoglycosides; Aminophenols; Anilides; Bacterial Proteins; Biological Products; Biosynthetic Pathways; Drug Discovery; Enediynes; Gene Expression Regulation, Bacterial; Genes, Bacterial; Lactams; Macrolides; Metabolic Engineering; Multigene Family; Piperidones; Polycyclic Compounds; Protein Conformation; Sequence Analysis, DNA; Streptomyces; Thiazoles; Thiones | 2019 |
19 other study(ies) available for thiazoles and adamantane
| Article | Year |
|---|---|
Protection against X-irradiation by some orally administered compounds.
Topics: Adamantane; Administration, Oral; Amidines; Animals; Male; Mice; Radiation-Protective Agents; Thiazoles | 1984 |
Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data.
Topics: Adamantane; Anti-Bacterial Agents; Antimalarials; Atovaquone; Biopharmaceutics; Chemical Phenomena; Chemistry, Physical; Chromans; Chromatography, High Pressure Liquid; Food-Drug Interactions; Lactams; Naphthoquinones; Phenylurea Compounds; Platelet Aggregation Inhibitors; Predictive Value of Tests; Prodrugs; Solubility; Solvents; Spectrophotometry, Ultraviolet; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration.
Topics: Adamantane; Administration, Oral; Algorithms; Anti-Bacterial Agents; Antifungal Agents; Atovaquone; Chemical Phenomena; Chemistry, Physical; Chromans; Humans; Hypoglycemic Agents; Lactams; Lipids; Models, Chemical; Naphthoquinones; Pharmaceutical Preparations; Pharmacokinetics; Phenylurea Compounds; Solubility; Thiazoles; Thiazolidinediones; Troglitazone | 2001 |
2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adamantane; Adipose Tissue; Animals; Cortisone; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Humans; Hydrocortisone; Hypoglycemic Agents; Ligands; Liver; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Triazoles | 2008 |
Mechanism of action of species-selective P2X(7) receptor antagonists.
Topics: Adamantane; Adenosine Triphosphate; Animals; Azabicyclo Compounds; Binding Sites; Cell Line, Tumor; Dogs; Dose-Response Relationship, Drug; Glycine; Guinea Pigs; Humans; Mice; Piperazines; Protein Conformation; Purinergic P2 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Recombinant Fusion Proteins; Recombinant Proteins; Species Specificity; Structure-Activity Relationship; Temperature; Thiazoles; Transduction, Genetic; Vanadates | 2009 |
Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer.
Topics: Adamantane; Aminophenols; Animals; Antineoplastic Agents, Hormonal; Base Sequence; Breast Neoplasms; Cell Line, Tumor; DNA Primers; Drug Resistance, Neoplasm; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Isoenzymes; Mice; Mice, Nude; Mice, SCID; Phosphotransferases (Alcohol Group Acceptor); Pyridines; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Thiazoles; Xenograft Model Antitumor Assays | 2012 |
Optimization of brain penetrant 11β-hydroxysteroid dehydrogenase type I inhibitors and in vivo testing in diet-induced obese mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adamantane; Animals; Blood Glucose; Body Weight; Brain; Crystallography, X-Ray; Cyclopropanes; Diabetes Mellitus, Type 2; Dietary Fats; Humans; Hypoglycemic Agents; Insulin; Isoenzymes; Liver; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Molecular; Pyrazoles; Rats; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2014 |
Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Interleukin-1beta; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Thiazoles; Tumor Necrosis Factor-alpha; Vitamin E | 2014 |
Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells.
Topics: Adamantane; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Movement; Hydrogen Peroxide; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; NADPH Oxidases; Neurodegenerative Diseases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Thiazoles; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Sortase A Inhibitors: Recent Advances and Future Perspectives.
Topics: Adamantane; Aminoacyltransferases; Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Proteins; Benzoates; Carbolines; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Models, Molecular; Nitriles; Protein Conformation; Rhodanine; Small Molecule Libraries; Staphylococcal Infections; Staphylococcus aureus; Thiazoles; Thiones | 2015 |
N-adamantyl-4-methylthiazol-2-amine suppresses lipopolysaccharide-induced brain inflammation by regulating NF-κB signaling in mice.
Topics: Adamantane; Analysis of Variance; Animals; Anti-Inflammatory Agents; Brain; Brain-Derived Neurotrophic Factor; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Encephalitis; Female; Gene Expression Regulation; Interleukin-1beta; Lipopolysaccharides; Malondialdehyde; Membrane Proteins; Mice; Mice, Inbred C57BL; Nitric Oxide; Prostaglandins E; Superoxide Dismutase; Thiazoles; Tumor Necrosis Factor-alpha | 2015 |
Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.
Topics: Adamantane; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Humans; Male; Oxidoreductases; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms, Castration-Resistant; Proteasome Endopeptidase Complex; Pyridines; Thiazoles | 2016 |
N-Adamantyl-4-methylthiazol-2-amine suppresses amyloid β-induced neuronal oxidative damage in cortical neurons.
Topics: Adamantane; Alzheimer Disease; Amyloid beta-Peptides; Animals; Neurons; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiazoles | 2016 |
Neuroprotective effects of N-adamantyl-4-methylthiazol-2-amine against amyloid β-induced oxidative stress in mouse hippocampus.
Topics: Adamantane; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Antioxidants; Catalase; Female; Glutathione; Glutathione Peroxidase; Group IV Phospholipases A2; Heme Oxygenase-1; Hippocampus; Interleukin-1beta; Matrix Metalloproteinase 2; Membrane Proteins; Mice, Inbred C57BL; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Superoxide Dismutase; Thiazoles; Tumor Necrosis Factor-alpha | 2017 |
Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice.
Topics: A549 Cells; Adamantane; Administration, Oral; Amino Alcohols; Aminophenols; Animals; Cell Line; Disease Models, Animal; Female; Gene Knockdown Techniques; HEK293 Cells; Humans; Influenza A virus; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Isoforms; Pyridines; RNA, Small Interfering; Sphingosine; Thiazoles; Virus Replication | 2018 |
Electrochemical Quantitation of Supramolecular Excipient@Drug Complexation: A General Assay Strategy Based on Competitive Host Binding with Surface-Immobilized Redox Guest.
Topics: Adamantane; Binding Sites; Bridged-Ring Compounds; Electrochemical Techniques; Ferrous Compounds; Imidazoles; Macromolecular Substances; Metallocenes; Molecular Structure; Oxidation-Reduction; Quaternary Ammonium Compounds; Surface Properties; Thiazoles | 2020 |
N-Adamantyl-4-methylthiazol-2-amine suppresses glutamate-induced autophagic cell death via PI3K/Akt/mTOR signaling pathways in cortical neurons.
Topics: Adamantane; Animals; Antioxidants; Autophagic Cell Death; Autophagy; Cerebral Cortex; Glutamic Acid; Glutathione; Glutathione Peroxidase; Neurons; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Thiazoles; TOR Serine-Threonine Kinases | 2020 |
Novel 2-(Adamantan-1-ylamino)Thiazol-4(5
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adamantane; Binding Sites; Enzyme Inhibitors; Hydrocortisone; Molecular Docking Simulation; Protein Binding; Thiazoles | 2021 |
Synthesis and in vitro antibacterial, antifungal, anti-proliferative activities of novel adamantane-containing thiazole compounds.
Topics: Adamantane; Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Molecular Docking Simulation; Thiazoles | 2022 |