thiazoles has been researched along with acyclovir in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Konno, K; Shigeta, S; Sudo, K; Yokota, T | 1 |
| Bach, U; Baumeister, J; Bender, W; Betz, UA; Eckenberg, P; Fischer, R; Frappa, I; Haebich, D; Handke, G; Hendrix, M; Henninger, K; Hewlett, G; Jensen, A; Keldenich, J; Kleymann, G; Kolb, J; Lockhoff, O; Mäben, J; Pevzner, V; Popp, A; Rübsamen-Waigmann, H; Schneider, U; Weber, O | 1 |
| Belldegrun, A; Berger, F; Black, ME; Gambhir, SS; Matherly, J; Nguyen, D; Pantuck, AJ; Wu, L; Zisman, A | 1 |
| Browne, A; Cordingley, MG; Dansereau, N; Duan, J; Faucher, AM; Liard, F; Liuzzi, M; Paris, W; Simoneau, B | 1 |
| Duan, J; Lambert, M; Liard, F; Paris, W | 1 |
| Cavalli, R; Civra, A; Donalisio, M; Ferruti, P; Lembo, D; Ranucci, E; Trotta, F | 1 |
| Cortesi, R; Drechsler, M; Esposito, E; Menegatti, E; Ravani, L; Romagnoli, R; Zaid, AN | 1 |
| Frost, AL; Itzhaki, RF; Wozniak, MA | 1 |
| Birkmann, A; Field, HJ; Huang, ML; Lay, EM; Mickleburgh, I; Zimmermann, H | 1 |
| Acosta, EP; James, SH; Larson, KB; Prichard, MN | 1 |
| Agut, H; Boutolleau, D; Brunet, C; Burrel, S; Collot, M; Rouard, C | 1 |
| Birkmann, A; Zimmermann, H | 1 |
| Birkmann, A; Corey, L; Fife, K; Huang, ML; Johnston, C; Magaret, A; Ruebsamen-Schaeff, H; Selke, S; Stobernack, HP; Timmler, B; Tyring, S; Wald, A; Warren, T; Zimmermann, H | 1 |
| Birkmann, A; Bonsmann, S; Collins, DJ; Goldner, T; Pfaff, T; Prichard, MN; Quenelle, DC; Rice, TL; Zimmermann, H | 1 |
| Elbe-Bürger, A; Matiasek, J; Mildner, M; Popow-Kraupp, T; Schmidt, R; Schuster, C; Tajpara, P; Vierhapper, M | 1 |
| Cannon, L; Farooq, H; Kingston, M; Tholouli, E; Ward, C | 1 |
| Abid, H; Boutolleau, D; Burrel, S; Fourgeaud, J; Frange, P; Lanternier, F; Loiseau, C; Pouvaret, A; Rouzaud, C; Serris, A | 1 |
2 review(s) available for thiazoles and acyclovir
| Article | Year |
|---|---|
Helicase-primase as a target of new therapies for herpes simplex virus infections.
Topics: Acyclovir; Animals; Antiviral Agents; DNA Helicases; DNA Primase; Drug Design; Drug Resistance, Viral; Herpes Simplex; Humans; Molecular Targeted Therapy; Oxadiazoles; Pyridines; Sulfonamides; Thiazoles; Viral Proteins | 2015 |
HSV antivirals - current and future treatment options.
Topics: Acyclovir; Antiviral Agents; Clinical Trials, Phase II as Topic; DNA Helicases; DNA Primase; Drug Resistance, Viral; Herpes Genitalis; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Oxadiazoles; Pyridines; Sulfonamides; Thiazoles; Viral Proteins | 2016 |
1 trial(s) available for thiazoles and acyclovir
| Article | Year |
|---|---|
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences: A Randomized Clinical Trial.
Topics: Acyclovir; Adult; Aged; Antiviral Agents; Cross-Over Studies; Double-Blind Method; Female; Herpes Genitalis; Herpesvirus 2, Human; Humans; Male; Middle Aged; Pyridines; Recurrence; Sulfonamides; Thiazoles; Valacyclovir; Valine; Virus Shedding; Young Adult | 2016 |
14 other study(ies) available for thiazoles and acyclovir
| Article | Year |
|---|---|
A sensitive assay system screening antiviral compounds against herpes simplex virus type 1 and type 2.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cell Survival; Coloring Agents; Embryo, Mammalian; Formazans; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Kinetics; Lung; Microbial Sensitivity Tests; Sensitivity and Specificity; Spectrophotometry; Tetrazolium Salts; Thiazoles; Time Factors; Viral Plaque Assay | 1994 |
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.
Topics: Acyclovir; Animals; Antiviral Agents; DNA Helicases; DNA Primase; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Guinea Pigs; Herpes Simplex; Humans; Infant, Newborn; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pregnancy; Pyridines; Safety; Sulfonamides; Thiazoles; Viral Proteins | 2002 |
Optimizing prostate cancer suicide gene therapy using herpes simplex virus thymidine kinase active site variants.
Topics: Acyclovir; Animals; Antiviral Agents; Apoptosis; Binding Sites; Blotting, Southern; Blotting, Western; Disease Progression; Dose-Response Relationship, Drug; Flow Cytometry; Ganciclovir; Genetic Therapy; Green Fluorescent Proteins; Guanosine; Humans; Luminescent Proteins; Male; Mice; Mice, SCID; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Prodrugs; Propidium; Prostatic Neoplasms; Simplexvirus; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Tomography, Emission-Computed; Tumor Cells, Cultured | 2002 |
Oral bioavailability and in vivo efficacy of the helicase-primase inhibitor BILS 45 BS against acyclovir-resistant herpes simplex virus type 1.
Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Biological Availability; DNA Helicases; DNA Primase; Dose-Response Relationship, Drug; Drug Resistance, Viral; Enzyme Inhibitors; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Nude; Pyridines; Thiazoles; Viral Proteins | 2003 |
A novel oral vehicle for poorly soluble HSV-helicase inhibitors: PK/PD validations.
Topics: Acyclovir; Animals; Antiviral Agents; Chemical Phenomena; Chemistry, Physical; DNA Helicases; DNA Primase; Dose-Response Relationship, Drug; Drinking; Drug Stability; Enzyme Inhibitors; Excipients; Female; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Pharmaceutical Vehicles; Pyridines; Simplexvirus; Thiazoles; Viral Proteins | 2004 |
Enhanced antiviral activity of Acyclovir loaded into beta-cyclodextrin-poly(4-acryloylmorpholine) conjugate nanoparticles.
Topics: Acrylamides; Acyclovir; Animals; Antiviral Agents; beta-Cyclodextrins; Cell Membrane Permeability; Cell Survival; Chlorocebus aethiops; Coumarins; Drug Carriers; Herpesvirus 1, Human; Morpholines; Nanoparticles; Particle Size; Polymers; Thiazoles; Vero Cells | 2009 |
Ethosomes for the delivery of anti-HSV-1 molecules: preparation, characterization and in vitro activity.
Topics: Acyclovir; Antiviral Agents; Cell Survival; Diffusion; Drug Compounding; Electrochemistry; Freeze Drying; Herpesvirus 1, Human; Microscopy, Electron, Scanning; Microsomes; Particle Size; Pharmaceutical Vehicles; Tetrazolium Salts; Thiazoles; Viral Plaque Assay | 2010 |
The helicase-primase inhibitor BAY 57-1293 reduces the Alzheimer's disease-related molecules induced by herpes simplex virus type 1.
Topics: Acyclovir; Alzheimer Disease; Amyloid beta-Peptides; Antiviral Agents; DNA Helicases; DNA Primase; Down-Regulation; Enzyme Inhibitors; Herpes Simplex; Herpesvirus 1, Human; Humans; Pyridines; Sulfonamides; tau Proteins; Thiazoles; Viral Proteins; Virus Replication | 2013 |
Baseline sensitivity of HSV-1 and HSV-2 clinical isolates and defined acyclovir-resistant strains to the helicase-primase inhibitor pritelivir.
Topics: Acyclovir; Antiviral Agents; DNA Helicases; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Microbial Sensitivity Tests; Pyridines; Sulfonamides; Thiazoles; United States; Viral Plaque Assay | 2013 |
High conservation of herpes simplex virus UL5/UL52 helicase-primase complex in the era of new antiviral therapies.
Topics: Acyclovir; Antiviral Agents; DNA Helicases; DNA Primase; Drug Resistance, Viral; Herpesvirus 2, Human; Humans; Immunocompromised Host; Oxadiazoles; Polymorphism, Genetic; Pyridines; Simplexvirus; Sulfonamides; Thiazoles; Viral Proteins | 2016 |
Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis.
Topics: Acyclovir; Animals; Antiviral Agents; Disease Models, Animal; Drug Therapy, Combination; Encephalitis, Herpes Simplex; Female; Humans; Mice; Pyridines; Sulfonamides; Thiazoles; Tissue Distribution; Treatment Outcome | 2018 |
A Preclinical Model for Studying Herpes Simplex Virus Infection.
Topics: Acyclovir; Adult; Aged; Antiviral Agents; Biopsy, Needle; Case-Control Studies; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunohistochemistry; In Vitro Techniques; Male; Middle Aged; Models, Biological; Pyridines; Reference Values; Statistics, Nonparametric; Sulfonamides; Thiazoles; Virus Replication; Young Adult | 2019 |
Use of pritelivir in refractory aciclovir-resistant herpes simplex virus type 2.
Topics: Acyclovir; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 2, Human; Humans; Pyridines; Sulfonamides; Thiazoles | 2021 |
Pritelivir for recurrent aciclovir-resistant herpes simplex virus 2 infections in immunocompromised patients.
Topics: Acyclovir; Antiviral Agents; Herpes Genitalis; Herpesvirus 2, Human; Humans; Immunocompromised Host; Sulfonamides; Thiazoles | 2022 |