Page last updated: 2024-08-21

thiazoles and acetaminophen

thiazoles has been researched along with acetaminophen in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (28.00)	18.7374
1990's	8 (16.00)	18.2507
2000's	13 (26.00)	29.6817
2010's	14 (28.00)	24.3611
2020's	1 (2.00)	2.80

Authors

Authors	Studies
Charyulu, RL; Nagasawa, HT; Roberts, JC; Zera, RT	1
Cannon, M; Leeder, JS; Nakhooda, A; Spielberg, SP	1
Fricke, RF; Goon, DJ; Nagasawa, HT; Roberts, JC; Zera, RT	1
Anderson, ME; Hwang, O; Meister, A	1
Hazama, H; Murase, T; Okuno, H; Sameshima, Y; Shiozaki, Y	1
Leguen, MA	1
Hazelton, GA; Hjelle, JJ; Klaassen, CD	1
Schütt, A; Siegers, CP; Strubelt, O	1
Chalmers, TM; Kellgren, JH; Platt, DS	1
Goon, DJ; Muldoon, WP; Nagasawa, HT; Zera, RT	1
Boettcher, B; Meister, A; Williamson, JM	1
Goon, DJ; Nagasawa, HT; Yuzon, DL; Zera, RT	1
Breivik, H; Samstad, B; Winnem, B	1
Faini, D; Pagella, PG; Turba, C	1
Cho, E; Jang, SH; Kim, ND; Lee, JW; Lee, MG	1
Engelhardt, G; Homma, D; Schlegel, K; Schnitzler, C; Utzmann, R	1
Fox, SM; Johnston, SA	1
Rommelspacher, H; Wlodek, L	1
Rommelspacher, H; Włodek, L	1
Eastmond, R; Lettis, S; Young, MA	1
Kosnik, M; Matjaz, F; Music, E; Suskovic, S	1
Ajami, AM; Fukagawa, NK; Hercules, E	1
Galchev, V; Kindt, E; Kostrubsky, VE; Ramachandran, V; Rose, K; Sinclair, JF; Sinz, M; Strom, SC; Venkataramanan, R; Wen, YH	1
Chen, TS; Ray, MB; Srinivasan, C; Williams, WM	1
Chen, TS; Nagasawa, HT; Srinivasan, C; Williams, WM	1
Bae, MA; Pie, JE; Song, BJ	1
Amoretti, L; Ballabeni, V; Barocelli, E; Incerti, M; Tognolini, M; Vicini, P	1
Kaneko, T; Li, J; Qin, LQ; Sato, A; Wang, PY; Wang, Y	1
Li, KM; Reyes, L; Tinworth, KD; Waters, KA; Yau, DF	1
Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM	1
Fujino, H; Nohta, H; Yamaguchi, M; Yoshida, H	1
Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C	1
Chappell, AS; D'Souza, DN; Iyengar, S; Pritchett, YL; Raskin, J; Smith, TR; Wang, F; Wernicke, JF	1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX	1
Kang, P; Li, J; Liu, G; Liu, W; Luo, R; Ma, X; Pei, F; Shen, B; Xie, Q; Zhou, Z	1
Asanuma, M; Kikkawa, Y; Kimoto, N; Miyazaki, I; Miyoshi, K; Murakami, S; Takeshima, M	1
Hale, LP; Kim, CJ; Kolstad, AM; Rodriguiz, RM	1
Flecknell, PA; Miller, AL; Roughan, JV; Wright-Williams, SL	1
Bailey, JA; Buckenmaier, CC; Butler, FK; Edgar, EP; Gandy, JV; Gross, K; Kotwal, RS; Montgomery, HR; O'Connor, KC; Shackelford, SA; Timby, JW; Wedmore, I	1
Melzig, MF; Sun, J; Xie, W; Zhang, X	1
Cap, AP; Dubick, MA; Martini, AK; Martini, WZ; Rodriguez, CM	1
Duggan, S; Dumerton-Shore, D; Gilron, I; McGrath, M; Orr, E; Rooney, R; Tu, D	1
Babanouri, N; Oshagh, M; Salehi, P; Torkan, S; Zarif Najafi, H	1
Altman, R; Gibofsky, A; Hochberg, M; Jaros, M; Young, C	1
Li, HY; Li, Z; Sun, LX; Wang, CF; Wang, XB; Zhang, JW	1
Alexiades, MM; Brummett, CM; Fields, KG; Gadulov, Y; Goon, AK; Goytizolo, EA; Jules-Elysee, KM; Kahn, RL; Lin, Y; Mayman, DJ; Padgett, DE; Westrich, G; YaDeau, JT	1
Andersen, ME; Cowie, DE; Deisenroth, C; LeCluyse, E; Peffer, RC; Soldatow, V; Trask, OJ	1
Dille, MJ; Draget, KI; Hattrem, MN	1
Carambia, A; Ghallab, A; Heeren, J; Herkel, J; Lohse, AW; Lommetz, C; Reinders, J; Schramm, C; Schuran, FA; Schwinge, D; Steudter, A; Wieschendorf, B; Zuehlke, S	1

Reviews

1 review(s) available for thiazoles and acetaminophen

Article	Year
Use of carprofen for the treatment of pain and inflammation in dogs. Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles	1997

Article

Year

Use of carprofen for the treatment of pain and inflammation in dogs.

Journal of the American Veterinary Medical Association, 1997, May-15, Volume: 210, Issue:10

Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles

1997

Trials

12 trial(s) available for thiazoles and acetaminophen

Article	Year
Single-blind clinical trial comparing use of fentiazac and paracetamol in postendodontic periodontitis. Clinical therapeutics, 1985, Volume: 7, Issue:2 Topics: Acetaminophen; Acetates; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Periodontitis; Root Canal Therapy; Thiazoles; Time Factors; Toothache	1985
Fenclozic acid. Lancet (London, England), 1970, Mar-28, Volume: 1, Issue:7648 Topics: Acetaminophen; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Placebos; Rheumatic Diseases; Thiazoles	1970
Evaluation in man of fenclozic acid (I.C.I. 54,450: Myalex), a new anti-inflamatory agent. II. Clinical trial in patients with rheumatoid arthritis. Annals of the rheumatic diseases, 1969, Volume: 28, Issue:6 Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspirin; Clinical Trials as Topic; Female; Hand; Humans; Isocitrate Dehydrogenase; Male; Placebos; Salicylates; Thiazoles	1969
Coadministration of acetaminophen and troglitazone: pharmacokinetics and safety. Journal of clinical pharmacology, 1998, Volume: 38, Issue:9 Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Chromans; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Humans; Hypoglycemic Agents; Male; Thiazoles; Thiazolidinediones; Troglitazone	1998
[Postoperative pain management in clinics of otolaryngology]. Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2006, Volume: 16, Issue:1 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Male; Meloxicam; Middle Aged; Naproxen; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Period; Sulfones; Thiazines; Thiazoles; Treatment Outcome	2006
An open-label 52-week clinical extension comparing duloxetine with routine care in patients with diabetic peripheral neuropathic pain. Pain medicine (Malden, Mass.), 2007, Volume: 8, Issue:6 Topics: Acetaminophen; Amitriptyline; Analgesics; Carbamazepine; Diabetes Complications; Diabetic Neuropathies; Diclofenac; Double-Blind Method; Duloxetine Hydrochloride; Female; Humans; Lipids; Male; Meloxicam; Middle Aged; Neuralgia; Pentoxifylline; Selective Serotonin Reuptake Inhibitors; Thiamine; Thiazines; Thiazoles; Thioctic Acid; Thiophenes; Time; Vitamin B 12	2007
Efficacy of celecoxib, meloxicam and paracetamol in elderly Kashin-Beck disease (KBD) patients. International orthopaedics, 2011, Volume: 35, Issue:9 Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Female; Health Status; Humans; Joints; Kashin-Beck Disease; Male; Meloxicam; Middle Aged; Pain; Pain Measurement; Pyrazoles; Sulfonamides; Thiazines; Thiazoles; Treatment Outcome; Young Adult	2011
A comparison of abdominal and scrotal approach methods of vasectomy and the influence of analgesic treatment in laboratory mice. Laboratory animals, 2012, Volume: 46, Issue:4 Topics: Abdomen; Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Drug Combinations; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Meloxicam; Mice; Pain; Pain Measurement; Pilot Projects; Scrotum; Surgery, Veterinary; Thiazines; Thiazoles; Time Factors; Vasectomy; Videotape Recording	2012
The effect of triple vs. double nonopioid therapy on postoperative pain and functional outcome after abdominal hysterectomy: a randomised double-blind control trial. European journal of anaesthesiology, 2015, Volume: 32, Issue:4 Topics: Acetaminophen; Adult; Amines; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Early Termination of Clinical Trials; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Meloxicam; Middle Aged; Morphine; Ontario; Pain Measurement; Pain, Postoperative; Recovery of Function; Thiazines; Thiazoles; Time Factors; Treatment Outcome	2015
Comparison of the effects of preemptive acetaminophen, ibuprofen, and meloxicam on pain after separator placement: a randomized clinical trial. Progress in orthodontics, 2015, Volume: 16 Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dental Occlusion; Double-Blind Method; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Mastication; Meloxicam; Orthodontic Appliances; Pain; Pain Measurement; Pain Perception; Premedication; Prospective Studies; Thiazines; Thiazoles; Young Adult	2015
Efficacy and safety of low-dose SoluMatrix meloxicam in the treatment of osteoarthritis pain: a 12-week, phase 3 study. Current medical research and opinion, 2015, Volume: 31, Issue:12 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Male; Meloxicam; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Thiazines; Thiazoles; Treatment Outcome	2015
Duloxetine and Subacute Pain after Knee Arthroplasty when Added to a Multimodal Analgesic Regimen: A Randomized, Placebo-controlled, Triple-blinded Trial. Anesthesiology, 2016, Volume: 125, Issue:3 Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Humans; Male; Meloxicam; Middle Aged; Oxycodone; Pain, Postoperative; Thiazines; Thiazoles; Treatment Outcome	2016

Other Studies

37 other study(ies) available for thiazoles and acetaminophen

Article	Year
Protection against acetaminophen hepatotoxicity by ribose-cysteine (RibCys). Pharmacology & toxicology, 1992, Volume: 70, Issue:4 Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Mice; Prodrugs; Thiazoles; Thiazolidines	1992
Drug metabolite toxicity assessed in human lymphocytes with a purified, reconstituted cytochrome P-450 system. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3 Topics: Acetaminophen; Animals; Cell Survival; Cytochrome P-450 Enzyme System; Glutathione; Glutathione Transferase; Humans; Lymphocytes; Male; NADP; Pyridines; Rats; Tetrazolium Salts; Thiazoles	1988
Prodrugs of L-cysteine as protective agents against acetaminophen-induced hepatotoxicity. 2-(Polyhydroxyalkyl)- and 2-(polyacetoxyalkyl)thiazolidine-4(R)-carboxylic acids. Journal of medicinal chemistry, 1987, Volume: 30, Issue:10 Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Cysteine; Drug Therapy; Glutathione; Liver; Methionine Sulfoximine; Mice; Prodrugs; Rats; Structure-Activity Relationship; Thiazoles; Thiazolidines	1987
Intracellular cysteine and glutathione delivery systems. Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2 Topics: Acetaminophen; Animals; Biological Transport, Active; Cysteine; Dipeptides; Glutathione; Intracellular Fluid; Kidney; Liver; Mice; Models, Biological; Pyroglutamate Hydrolase; Pyrrolidonecarboxylic Acid; Sulfur; Thiazoles; Thiazolidines	1986
Effect of H2-receptor antagonists on acetaminophen-induced hepatic injury. Japanese journal of pharmacology, 1986, Volume: 41, Issue:4 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Famotidine; Glutathione; Liver; Liver Diseases; Male; Methylcholanthrene; Microsomes, Liver; Ranitidine; Rats; Thiazoles	1986
Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:1 Topics: Acetaminophen; Acetylcysteine; Animals; Biotransformation; Cysteine; Glucuronates; Glucuronic Acid; Glutathione; Kinetics; Liver; Liver Glycogen; Male; Mice; Phosphoadenosine Phosphosulfate; Protein Binding; Pyrrolidonecarboxylic Acid; Structure-Activity Relationship; Thiazoles; Thiazolidines	1986
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning. Archives of toxicology, 1974, Volume: 33, Issue:1 Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid	1974
2-Substituted thiazolidine-4(R)-carboxylic acids as prodrugs of L-cysteine. Protection of mice against acetaminophen hepatotoxicity. Journal of medicinal chemistry, 1984, Volume: 27, Issue:5 Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cysteine; Indicators and Reagents; Kinetics; Liver; Male; Mice; Mitochondria, Liver; Proline Oxidase; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazoles	1984
Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis. Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:20 Topics: Acetaminophen; Animals; Cysteine; Glutathione; Glutathione Synthase; Inactivation, Metabolic; Liver; Mice; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines	1982
Prodrugs of L-cysteine as liver-protective agents. 2(RS)-Methylthiazolidine-4(R)-carboxylic acid, a latent cysteine. Journal of medicinal chemistry, 1982, Volume: 25, Issue:5 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Cysteine; Magnetic Resonance Spectroscopy; Mice; Thiazoles	1982
Paracetamol, tiaramide and placebo for pain relief after orthopedic surgery. Acta anaesthesiologica Scandinavica, 1981, Volume: 25, Issue:3 Topics: Acetaminophen; Adolescent; Adult; Analgesics; Benzothiazoles; Double-Blind Method; Female; Humans; Male; Middle Aged; Orthopedics; Pain, Postoperative; Piperazines; Random Allocation; Thiazoles; Time Factors	1981
[Activity of arginine thiazolidin carboxylate on the acute poisoning by paracetamol in mice]. Bollettino chimico farmaceutico, 1980, Volume: 119, Issue:4 Topics: Acetaminophen; Animals; Arginine; Liver; Male; Mice; Thiazoles; Thiazolidines	1980
Metabolic changes of acetaminophen after intravenous administration to rats pretreated with a hepatoprotective agent, YH-439. Research communications in molecular pathology and pharmacology, 1996, Volume: 91, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Bile; Half-Life; Injections, Intravenous; Liver; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley; Thiazoles	1996
General pharmacology of meloxicam--Part II: Effects on blood pressure, blood flow, heart rate, ECG, respiratory minute volume and interactions with paracetamol, pirenzepine, chlorthalidone, phenprocoumon and tolbutamide. General pharmacology, 1996, Volume: 27, Issue:4 Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Blood Pressure; Cats; Chlorthalidone; Diuretics; Dogs; Drug Interactions; Electrocardiography; Guinea Pigs; Heart Rate; Hemodynamics; Hypoglycemic Agents; Meloxicam; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Phenprocoumon; Pirenzepine; Rabbits; Rats; Rats, Inbred Strains; Regional Blood Flow; Respiratory Mechanics; Thiazines; Thiazoles; Tolbutamide	1996
2-Methyl-thiazolidine-2,4-dicarboxylic acid as prodrug of L-cysteine. Protection against paracetamol hepatotoxicity in mice. Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:5 Topics: Acetaminophen; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Liver Diseases; Liver Function Tests; Male; Mice; Oxidative Stress; Prodrugs; Thiazoles; Thiazolidines	1997
2-Methyl-thiazolidine-2,4-dicarboxylic acid protects against paracetamol induced toxicity in human liver derived HepG2 cells. Acta biochimica Polonica, 1997, Volume: 44, Issue:4 Topics: Acetaminophen; Antidotes; Benzoquinones; Cell Line; Cysteine; Glutathione; Humans; Imines; Liver; Malondialdehyde; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Thiazoles; Thiazolidines	1997
Relative safety of meloxicam in NSAID-intolerant patients. Allergy, 1998, Volume: 53, Issue:12 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Female; Humans; Male; Meloxicam; Safety; Thiazines; Thiazoles; Urticaria	1998
L-2-[(13)C]oxothiazolidine-4-carboxylic acid: a probe for precursor mobilization for glutathione synthesis. American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:1 Topics: Acetaminophen; Adult; Aged; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Cysteine; Female; Glutathione; Humans; Kinetics; Male; Middle Aged; Models, Biological; Prodrugs; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines	2000
The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures. Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:10 Topics: Acetaminophen; Animals; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Hepatocytes; Humans; Nitrophenols; Pentachlorophenol; Phenobarbital; Protein Biosynthesis; Proteins; Swine; Thiazoles; Thiazolidinediones; Troglitazone	2000
Prevention of acetaminophen-induced liver toxicity by 2(R,S)-n-propylthiazolidine-4(R)-carboxylic acid in mice. Biochemical pharmacology, 2001, Jan-15, Volume: 61, Issue:2 Topics: Acetaminophen; Aldehydes; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Glutathione Disulfide; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Prodrugs; Protective Agents; Thiazoles	2001
Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on extrahepatic sulfhydryl levels in mice treated with acetaminophen. Biochemical pharmacology, 2001, Apr-01, Volume: 61, Issue:7 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Brain; Cysteine; Drug Interactions; Glutathione; Hepatocytes; In Vitro Techniques; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; Prodrugs; Sulfhydryl Compounds; Thiazoles; Tissue Distribution	2001
Acetaminophen induces apoptosis of C6 glioma cells by activating the c-Jun NH(2)-terminal protein kinase-related cell death pathway. Molecular pharmacology, 2001, Volume: 60, Issue:4 Topics: Acetaminophen; Acetanilides; Analgesics; Analgesics, Non-Narcotic; Androstadienes; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cytochrome c Group; Cytochrome P-450 CYP2E1; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glioma; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Thiazoles; Time Factors; Tumor Cells, Cultured; Wortmannin	2001
Synthesis and pharmacological properties of benzisothiazole/benzimidazole derivatives with acidic groups. Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:5 Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Benzimidazoles; Escherichia coli; Female; Guinea Pigs; Ileum; Lethal Dose 50; Lipopolysaccharides; Male; Mice; Pain; Pain Measurement; Parasympatholytics; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship; Thiazoles	2002
Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats. Toxicology, 2002, Jul-01, Volume: 176, Issue:1-2 Topics: Acetaminophen; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromans; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Hypoglycemic Agents; Injections, Intraperitoneal; Male; Oxidoreductases, N-Demethylating; Rats; Rats, Mutant Strains; Rats, Wistar; Thiazoles; Thiazolidinediones; Troglitazone	2002
Observer-blinded comparison of two nonopioid analgesics for postoperative pain in piglets. Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Blood Pressure; Body Temperature; Half-Life; Heart Rate; Kidney; Liver; Meloxicam; Models, Biological; Pain Measurement; Pain, Postoperative; Respiratory Mechanics; Swine; Thiazines; Thiazoles	2002
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. Basic & clinical pharmacology & toxicology, 2005, Volume: 96, Issue:6 Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines	2005
HPLC determination of acetaminophen in saliva based on precolumn fluorescence derivatization with 12-(3,5-dichloro-2,4,6-triazinyl)benzo[d]benzo[1',2'-6,5]isoindolo[1,2-b][1,3]thiazolidine. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2005, Volume: 21, Issue:9 Topics: Acetaminophen; Chromatography, High Pressure Liquid; Fluorescence; Humans; Indoles; Isoindoles; Male; Middle Aged; Saliva; Thiazoles; Thiazolidines	2005
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. Chemical research in toxicology, 2008, Volume: 21, Issue:9 Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles	2008
Cyclooxygenase-independent neuroprotective effects of aspirin against dopamine quinone-induced neurotoxicity. Neurochemical research, 2012, Volume: 37, Issue:9 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aspirin; Cell-Free System; Cells, Cultured; Cyclooxygenase Inhibitors; Dopamine Agents; Dopaminergic Neurons; Glutathione; Indomethacin; Levodopa; Meloxicam; Methyldopa; Mice; Neurons; Neuroprotective Agents; Quinones; Sympatholytics; Thiazines; Thiazoles	2012
Effect of pain management on immunization efficacy in mice. Journal of the American Association for Laboratory Animal Science : JAALAS, 2012, Volume: 51, Issue:4 Topics: Acetaminophen; Analgesia; Analgesics; Animals; Animals, Laboratory; Antibody Formation; Behavior, Animal; Buprenorphine; Freund's Adjuvant; Immunization; Lipids; Meloxicam; Mice; Pain; Pain Management; Thiazines; Thiazoles	2012
A Triple-Option Analgesia Plan for Tactical Combat Casualty Care: TCCC Guidelines Change 13-04. Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, 2014,Spring, Volume: 14, Issue:1 Topics: Acetaminophen; Administration, Buccal; Analgesia; Analgesics; Analgesics, Opioid; Fentanyl; Humans; Injections, Intravenous; Ketamine; Meloxicam; Military Medicine; Morphine; Practice Guidelines as Topic; Thiazines; Thiazoles; United States; Warfare; Wounds and Injuries	2014
Necrosis factor-alpha (TNF-alpha) response in human hepatoma HepG2 cells treated with hepatotoxic agents. Die Pharmazie, 2014, Volume: 69, Issue:5 Topics: Acetaldehyde; Acetaminophen; Cell Line; Cell Survival; Central Nervous System Depressants; Chemical and Drug Induced Liver Injury; Coloring Agents; Ethanol; Humans; Liver; tert-Butylhydroperoxide; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha	2014
Acetaminophen and meloxicam inhibit platelet aggregation and coagulation in blood samples from humans. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2014, Volume: 25, Issue:8 Topics: Acetaminophen; Arachidonic Acid; Blood Cells; Blood Coagulation; Blood Specimen Collection; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Humans; Meloxicam; Partial Thromboplastin Time; Platelet Aggregation; Prothrombin Time; Thiazines; Thiazoles; Thrombelastography	2014
[Determination of the interaction kinetics between meloxicam and β-cyclodextrin using the quantitative high-performance affinity chromatography coupled with mass spectrometry]. Yao xue xue bao = Acta pharmaceutica Sinica, 2015, Volume: 50, Issue:9 Topics: Acetaminophen; beta-Cyclodextrins; Chromatography, Affinity; Drug Interactions; Kinetics; Mass Spectrometry; Meloxicam; Thermodynamics; Thiazines; Thiazoles	2015
Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation. Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 36 Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Biological Assay; Cell Proliferation; Cell Survival; Cells, Cultured; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; DNA; Epidermal Growth Factor; Hepatocytes; Humans; Male; Membrane Proteins; Mice; Microscopy, Fluorescence; Oximes; Phenobarbital; Pyridines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Species Specificity; Steroid Hydroxylases; Thiazoles	2016
Soft, chewable gelatin-based pharmaceutical oral formulations: a technical approach. Pharmaceutical development and technology, 2018, Volume: 23, Issue:5 Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Drug Compounding; Gelatin; Hardness; Humans; Ibuprofen; Mastication; Meloxicam; Solubility; Sweetening Agents; Tablets; Taste Perception; Thiazines; Thiazoles; Transition Temperature; Xylitol	2018
Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice. Cellular and molecular gastroenterology and hepatology, 2021, Volume: 11, Issue:2 Topics: Acetaminophen; Animals; Basic Helix-Loop-Helix Transcription Factors; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Hepatocytes; Humans; Indoles; Liver; Liver Failure, Acute; Male; Mice; Mice, Knockout; Receptors, Aryl Hydrocarbon; Thiazoles	2021