Page last updated: 2024-08-21

thiazoles and abt 299

thiazoles has been researched along with abt 299 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albert, DH; Carter, GW; Conway, RG; Davidsen, SK; Holms, JH; Luo, G; Magoc, TJ; Rhein, DA; Summers, JB; Tapang, P2
Albert, DH; Carter, GW; Grossman, JE; Kruse-Elliott, KT; Summers, JB; Zimmerman, JJ1
Albert, DH; Carter, GW; Davidsen, SK; Holms, JH; Luo, G; Magoc, TJ; Summers, JB; Tapang, P1
Albert, DH; Carter, GW; Kleinert, HD; Magoc, TJ; Reyes, AE; Summers, JB; Sun, E1
Albert, DH; Carter, GW; Kleinert, HD; Magoc, TJ; Menacherry, SD; Morgan, DW; Reyes, AE; Summers, JB; Sun, E1
Lefferts, PL; Lu, W; Snapper, JR; Thabes, JS1

Trials

2 trial(s) available for thiazoles and abt 299

ArticleYear
Ex vivo inhibition of PAF-induced beta-thromboglobulin release in man by ABT-299, a potent PAF antagonist.
    Advances in experimental medicine and biology, 1996, Volume: 416

    Topics: Adolescent; Adult; beta-Thromboglobulin; Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Injections, Intravenous; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prodrugs; Pyridinium Compounds; Spectrophotometry, Ultraviolet; Thiazoles

1996
Ex vivo inhibition of beta-thromboglobulin release following administration to man of ABT-299, a novel prodrug of a potent platelet activating factor antagonist.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1997, Volume: 46, Issue:7

    Topics: Adolescent; Adult; beta-Thromboglobulin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Double-Blind Method; Humans; In Vitro Techniques; Indoles; Injections, Intravenous; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prodrugs; Pyridinium Compounds; Thiazoles

1997

Other Studies

5 other study(ies) available for thiazoles and abt 299

ArticleYear
ABT-299, a potent antagonist of platelet activating factor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1995, Volume: 23

    Topics: Animals; Binding, Competitive; Blood Pressure; Edema; Esterases; Humans; Hypotension; Indoles; Kinetics; Lipopolysaccharides; Mice; Molecular Structure; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Thiazoles

1995
Properties of ABT-299, a prodrug of A-85783, a highly potent platelet activating factor receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3

    Topics: Animals; Binding, Competitive; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Kinetics; Mice; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prodrugs; Pyridinium Compounds; Rabbits; Rats; Thiazoles

1996
Attenuation of endotoxin-induced pathophysiology by a new potent PAF receptor antagonist.
    Shock (Augusta, Ga.), 1996, Volume: 5, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Lipopolysaccharides; Lung; Peroxidase; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Septic; Stroke Volume; Swine; Thiazoles; Thromboxane B2; Vascular Resistance

1996
ABT-299, a novel PAF antagonist, attenuates multiple effects of endotoxemia in conscious rats.
    Shock (Augusta, Ga.), 1996, Volume: 6, Issue:2

    Topics: Animals; Consciousness; Disseminated Intravascular Coagulation; Endotoxemia; Endotoxins; Gastrointestinal Hemorrhage; Hypotension; Lipopolysaccharides; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Teichoic Acids; Thiazoles

1996
Effect of platelet-activating factor-receptor antagonism on endotoxin-induced lung dysfunction in sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:5

    Topics: Animals; Blood Pressure; Endotoxins; Humans; Infant, Newborn; Leukocyte Count; Lung; Oxygen; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prodrugs; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests; Sheep; Thiazoles

1998