Compounds > thiazoles
Page last updated: 2024-08-21

thiazoles and 5-methyl-n-(4-methylpyrimidin-2-yl)-4-(1h-pyrazol-4-yl)thiazol-2-amine

thiazoles has been researched along with 5-methyl-n-(4-methylpyrimidin-2-yl)-4-(1h-pyrazol-4-yl)thiazol-2-amine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bate, ST; Boléa, C; Browne, SE; Campo, B; Celanire, S; Davis, MJ; Duvoisin, R; Fonsi, M; Girard, F; Kalinichev, M; Le Poul, E; Poli, S; Raber, J; Reynolds, IJ; Royer-Urios, I; Uslaner, JM1
Albini, E; Antognelli, C; Belladonna, ML; Bianchi, R; Bicciato, S; Cacquevel, M; Calvitti, M; Celanire, S; Fallarino, F; Galibert, L; Gargaro, M; Grohmann, U; Heroux, M; Iacono, A; Mondanelli, G; Mordant, C; Orabona, C; Pallotta, MT; Poli, SM; Puccetti, P; Royer-Urios, I; Schneider, M; Solari, A; Vacca, C; Vitte, PA; Volpi, C1
Fujinaga, M; Kawamura, K; Kumata, K; Nengaki, N; Ogawa, M; Shimoda, Y; Xie, L; Yamasaki, T; Yui, J; Zhang, MR; Zhang, Y1
Conn, PJ; Gogliotti, R; Harms, AS; Jurkuvenaite, A; Niswender, CM; Ponnazhagan, R; Standaert, DG; Thome, AD1

Other Studies

4 other study(ies) available for thiazoles and 5-methyl-n-(4-methylpyrimidin-2-yl)-4-(1h-pyrazol-4-yl)thiazol-2-amine

ArticleYear
Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 350, Issue:3

    Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Disease Models, Animal; Female; Male; Mental Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Thiazoles

2014
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells.
    Neuropharmacology, 2016, Volume: 102

    Topics: Allosteric Regulation; Animals; Dendritic Cells; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Phosphatidylinositol 3-Kinases; Pyrimidines; Receptors, Metabotropic Glutamate; RNA, Small Interfering; Signal Transduction; Thiazoles

2016
Radiosynthesis and evaluation of 5-methyl-N-(4-[(11)C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([(11)C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4).
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Animals; Autoradiography; Brain; Male; Positron-Emission Tomography; Pyrimidines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Thiazoles; Tissue Distribution

2016
The Metabotropic Glutamate Receptor 4 Positive Allosteric Modulator ADX88178 Inhibits Inflammatory Responses in Primary Microglia.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2016, Volume: 11, Issue:2

    Topics: Allosteric Regulation; Animals; Anti-Inflammatory Agents; Cells, Cultured; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Pyrimidines; Receptors, Metabotropic Glutamate; Thiazoles

2016