thiazoles has been researched along with 3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 26 (96.30) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Binnaka, T; Fujimura, K; Inoue, K; Kitagawa, S; Kubota, Y; Mizuno, T; Tani, K; Yamaguchi, T | 1 |
| Imanishi, N; Morooka, S; Uchida, M | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T | 1 |
| Imanishi, N; Komuro, Y; Morooka, S | 1 |
| Imanishi, N; Komuro, Y; Morooka, S; Uchida, M | 1 |
| Asakura, K; Narita, S | 2 |
| Imanishi, N; Koike, H; Morooka, S; Natsume, Y | 2 |
| Imanishi, N; Koike, H; Morooka, S; Murakami-Uchida, M; Natsume, Y | 1 |
| Bourdon, V; Damas, J; Remacle-Volon, G | 1 |
| Aosasa, S; Kinoshita, M; Mochizuki, H; Oda, Y; Ohe, H; Ohkusa, Y; Ono, S; Tamakuma, S | 1 |
| Doi, T; Nakazawa, H; Okamoto, M; Takahashi, K; Ueda, Y | 1 |
| Funae, Y; Funayama, M; Green, C; Inoue, K; Kamataki, T; Kimura, K; Kodama, T; Nagashima, K; Nunoya, K; Shimada, N; Yokoi, Y | 1 |
| Itoh, K; Itoh, S; Kamataki, T; Kimura, K; Nunoya, K; Yokoi, T | 1 |
| Johno, M; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Hilger, RA; Köller, M; König, W | 2 |
| Morooka, S; Natsume, Y | 1 |
| Akiyama, M; Ino, M; Miwa, M; Shimura, M; Sugatani, J; Suzuki, M; Suzuki, Y; Yamazaki, R | 1 |
| Aikawa, T; Han, L; Hirose, T; Iwasaki, K; Koyanagi, M; Matsumoto, I; Shimada, T; Yang, H | 1 |
| Funae, Y; Funayama, M; Green, C; Inoue, K; Kamataki, T; Kimura, K; Kinoshita, M; Kodama, T; Nagashima, K; Nunoya, K; Yokoi, T | 1 |
| Kamataki, T; Yokoi, T | 1 |
| Higure, A; Itoh, H; Katoh, H; Nagafuchi, Y; Nakamura, S; Ohsato, K; Okamoto, K; Okazaki, K; Takeda, S; Todoroki, H | 1 |
| Kainuma, T; Kamataki, T; Kimura, K; Kinoshita, M; Nunoya, KI; Satoh, K; Yokoi, T | 1 |
| Hayashi, J; Hiromura, K; Koizumi, R; Maezawa, A; Naruse, T; Nojima, Y; Shimizu, Y | 1 |
1 review(s) available for thiazoles and 3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one
| Article | Year |
|---|---|
[Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese].
Topics: Alleles; Animals; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Genotype; Humans; Japan; Mixed Function Oxygenases; Mutation; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Substrate Specificity; Thiazoles; Thiazolidines | 1998 |
26 other study(ies) available for thiazoles and 3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one
| Article | Year |
|---|---|
Burn-induced gastric mucosal hemodynamic disturbance in the rat. Role of platelet-activating factor.
Topics: Animals; Azepines; Blood Pressure; Burns; Gastric Mucosa; Hemodynamics; Hemoglobins; Male; Oxygen; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Inbred Strains; Regional Blood Flow; Thiazoles; Thiazolidines; Triazoles | 1992 |
Platelet-activating factor (PAF) plays an important role in the immediate asthmatic response in guinea-pig by augmenting the response to histamine.
Topics: Anaphylaxis; Animals; Asthma; Bronchi; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Platelet Count; Pyridinium Compounds; Respiratory Function Tests; SRS-A; Thiazoles; Thiazolidines | 1992 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 2. Effect on antigen-induced dual asthmatic response and infiltration of leukocytes into airways in actively sensitized conscious guinea pigs.
Topics: Animals; Antigens; Asthma; Cromolyn Sodium; Disease Models, Animal; Fenoterol; Guinea Pigs; Leukocytes; Lung; Male; Ovalbumin; Platelet Activating Factor; Respiratory Function Tests; Respiratory System; Thiazoles; Thiazolidines | 1991 |
Effect of a selective PAF antagonist SM-10661 ((+/-)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one HCl) on experimental disseminated intravascular coagulation (DIC).
Topics: Administration, Oral; Animals; Disseminated Intravascular Coagulation; Endotoxins; Fibrin Fibrinogen Degradation Products; Fibrinogen; Gabexate; Infusions, Intravenous; Injections, Intraperitoneal; Partial Thromboplastin Time; Platelet Activating Factor; Platelet Count; Prothrombin Time; Rats; Thiazoles; Thiazolidines | 1991 |
Biological effect of orally active platelet-activating factor receptor antagonist SM-10661.
Topics: Administration, Oral; Animals; Blood Pressure; Bronchi; Guinea Pigs; Humans; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1990 |
The role of platelet-activating factor on histamine hypersensitivity in nasal allergy in guinea pig models.
Topics: Allergens; Animals; Guinea Pigs; Histamine Release; Hypersensitivity; Male; Ovalbumin; Platelet Activating Factor; Thiazoles; Thiazolidines | 1993 |
Effect of the platelet activating factor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride on endotoxin-induced hypotension and hematological parameters in rats.
Topics: Animals; Blood Coagulation; Blood Pressure; Dose-Response Relationship, Drug; Endotoxins; Fibrin Fibrinogen Degradation Products; In Vitro Techniques; Iodine Radioisotopes; Male; Platelet Activating Factor; Platelet Count; Rats; Rats, Wistar; Thiazoles; Thiazolidines | 1994 |
Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils.
Topics: Animals; Azepines; Binding, Competitive; Calcium; Cell Count; Cell Degranulation; Chemotaxis, Leukocyte; Free Radical Scavengers; Inositol 1,4,5-Trisphosphate; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reference Standards; Signal Transduction; Structure-Activity Relationship; Superoxides; Thiazoles; Thiazolidines; Triazoles; Vitamin E | 1994 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Biological effects of the new platelet-activating factor receptor antagonist (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride.
Topics: Anaphylaxis; Animals; Blood Platelets; Blood Pressure; Endotoxins; Guinea Pigs; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stereoisomerism; Thiazoles; Thiazolidines | 1994 |
Platelet-activating factor and the vascular effects of zymosan in rats.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Female; Hematocrit; Hemodynamics; Iodine Radioisotopes; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Triazoles; Zymosan | 1993 |
Clinical and experimental studies on the role of platelet-activating factor (PAF) in the pathogenesis of septic DIC.
Topics: Aged; Animals; Blood Pressure; Disseminated Intravascular Coagulation; Female; Fibrinolysis; Guanidines; Humans; Male; Middle Aged; Neoplasms; Platelet Activating Factor; Platelet Count; Postoperative Complications; Rabbits; Serine Proteinase Inhibitors; Shock, Septic; Thiazoles; Thiazolidines | 1993 |
Direct enantiomeric separation of platelet-activating factor receptor antagonist SM-10661 by ligand-exchange high-performance liquid chromatography with a copper (II) N,S-dioctyl-D-penicillamine complex.
Topics: Cations; Chromatography, High Pressure Liquid; Copper; Isomerism; Penicillamine; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1995 |
(+)-cis-3,5-dimethyl-2-(3-pyridyl) thiazolidin-4-one hydrochloride (SM-12502) as a novel substrate for cytochrome P450 2A6 in human liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Rats; Thiazoles; Thiazolidines | 1996 |
S-oxidation of (+)-cis-3,5-dimethyl-2-(3-pyridyl)-thiazolidin-4-one hydrochloride by rat hepatic flavin-containing monooxygenase 1 expressed in yeast.
Topics: Animals; Hydrogen-Ion Concentration; Microsomes, Liver; Oxidation-Reduction; Oxygenases; Platelet Activating Factor; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Thiazoles; Thiazolidines | 1995 |
A novel platelet activating factor antagonist, SM-12502, attenuates endotoxin-induced disseminated intravascular coagulation and acute pulmonary vascular injury by inhibiting TNF production in rats.
Topics: Animals; Blood Coagulation; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Female; Humans; Infant, Newborn; Platelet Activating Factor; Pulmonary Artery; Rats; Rats, Wistar; Respiratory Distress Syndrome, Newborn; Thiazoles; Thiazolidines | 1996 |
Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502.
Topics: Aluminum; Basophils; Calcimycin; Calcium; Depression, Chemical; Gene Expression Regulation; GTP-Binding Proteins; Humans; Interleukin-8; Ionophores; Leukocytes, Mononuclear; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines | 1996 |
Effect of the PAF-receptor antagonist SM-12502 on human platelets.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Aluminum; Arachidonate 12-Lipoxygenase; Calcimycin; Calcium; Fatty Acids, Unsaturated; Gene Expression Regulation; GTP-Binding Proteins; Humans; Ionophores; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Fluoride; Thiazoles; Thiazolidines; Thrombin | 1996 |
Effect of SM-12502 on disseminated intravascular coagulation (DIC) in tumor-bearing rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disseminated Intravascular Coagulation; Injections, Intravenous; Liver Neoplasms, Experimental; Male; Neoplasm Transplantation; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured | 1996 |
Continuous binding of the PAF molecule to its receptor is necessary for the long-term aggregation of platelets.
Topics: Animals; Azepines; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Neutrophils; P-Selectin; Phospholipid Ethers; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines; Triazoles | 1998 |
Effect of PAF receptor antagonists on adrenocortical secretion induced by ACTH in normal and athymic nude mice.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Colforsin; Corticosterone; Male; Mice; Mice, Inbred ICR; Mice, Nude; Platelet Membrane Glycoproteins; Pyridinium Compounds; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thiazoles; Thiazolidines | 1998 |
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502).
Topics: Aryl Hydrocarbon Hydroxylases; Base Sequence; Cloning, Molecular; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Gene Deletion; Genomic Library; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Substrate Specificity; Thiazoles; Thiazolidines | 1998 |
Possible role of platelet-activating factor in the in vivo expression of tissue factor in neutrophils.
Topics: Animals; Aspartate Aminotransferases; Blood Coagulation; Cholangitis; Disease Models, Animal; Leukocytes; Liver; Male; Neutrophils; Platelet Activating Factor; Rabbits; Thiazoles; Thiazolidines; Thromboplastin | 1998 |
A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans.
Topics: Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Southern; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Deoxyribonucleases, Type II Site-Specific; DNA; Exons; Gene Library; Humans; Leukocytes; Male; Mixed Function Oxygenases; Molecular Sequence Data; Phenotype; Platelet Aggregation Inhibitors; Polymorphism, Restriction Fragment Length; Reverse Transcriptase Polymerase Chain Reaction; Sequence Deletion; Thiazoles; Thiazolidines | 1999 |
Platelet-activating factor antagonist, SM-12502, attenuates experimental glomerular thrombosis in rats.
Topics: Animals; Fibrin; Kidney Glomerulus; Lipopolysaccharides; Male; Neutrophil Activation; Peroxidase; Platelet Activating Factor; Rats; Rats, Wistar; Thiazoles; Thiazolidines; Thrombosis | 2001 |