thiazoles has been researched along with 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)piperidine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Gass, JT; Olive, MF | 1 |
| Baptista, MA; Dayas, CV; Martin-Fardon, R; Weiss, F | 1 |
| Brotchie, JM; Fox, SH; Johnston, TH; McIldowie, MJ; Piggott, MJ | 1 |
| Gao, C; Guedea, AL; Guzman, YF; Huh, KH; Radulovic, J; Schwarz, MK; Tronson, NC | 1 |
| Martin-Fardon, R; Weiss, F | 1 |
| Brown, RM; Duncan, JR; Lawrence, AJ; Stagnitti, MR | 1 |
| Arnold, JC; Cain, ME; Gill, MJ | 1 |
| Konitsiotis, S; Maranis, S; Stamatis, D; Tsironis, C | 1 |
| Brański, P; Pałucha-Poniewiera, A; Pilc, A; Stachowicz, K; Sławińska, A; Wierońska, JM | 1 |
| Bi, GH; Gardner, EL; Keck, TM; Newman, AH; Srivastava, R; Wang, XF; Xi, ZX; Yang, HJ; Zhang, HY; Zou, MF | 1 |
| Feng, Y; Hartmann, B; Holst, JJ; Teitelbaum, DH; Xiao, W; Yang, H | 1 |
| de Groat, WC; Kadow, BT; Lamm, V; Lyon, TD; Roppolo, JR; Shen, B; Tai, C; Wang, J; Zhang, Z | 1 |
| Kouvaros, S; Papatheodoropoulos, C | 1 |
| Berardo, C; Di Pasqua, LG; Ferrigno, A; Nicoletti, F; Richelmi, P; Siciliano, V; Vairetti, M | 1 |
| Asp, AJ; Benneyworth, MA; Ebner, SR; Hearing, MC; Ingebretson, AE; Larson, EB; Madayag, A; Schmidt, CE; Silvis, KA; Thomas, MJ | 1 |
| Gobin, CM; Hámor, PU; Schwendt, M | 1 |
| Gu, L; Huang, YL; Wang, Y; Yang, HM; Zhang, H; Zhang, JN | 1 |
17 other study(ies) available for thiazoles and 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)piperidine
| Article | Year |
|---|---|
Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell.
Topics: Animals; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Antagonists; Feeding Behavior; Male; Motor Activity; Nucleus Accumbens; Piperidines; Protein Kinase C-epsilon; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Signal Transduction; Thiazoles | 2009 |
Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcer.
Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extinction, Psychological; Locomotion; Male; Milk; Piperidines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Reinforcement, Psychology; Self Administration; Thiazoles | 2009 |
Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Male; Motor Activity; MPTP Poisoning; Parkinson Disease, Secondary; Piperidines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiazoles | 2010 |
Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear.
Topics: Analysis of Variance; Animals; Association Learning; Blotting, Western; Carrier Proteins; Cells, Cultured; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Fear; Hippocampus; Homer Scaffolding Proteins; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Neurons; Piperidines; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Restraint, Physical; Stress, Physiological; Stress, Psychological; Thiazoles | 2010 |
(-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking.
Topics: Amino Acids; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Stimulants; Cocaine-Related Disorders; Conditioning, Operant; Excitatory Amino Acid Antagonists; Extinction, Psychological; Male; Piperidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stress, Psychological; Thiazoles | 2012 |
The mGlu5 receptor antagonist MTEP attenuates opiate self-administration and cue-induced opiate-seeking behaviour in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Piperidines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Self Administration; Substance Abuse, Intravenous; Thiazoles | 2012 |
Impact of mGluR5 during amphetamine-induced hyperactivity and conditioned hyperactivity in differentially reared rats.
Topics: Amphetamine; Animals; Behavior, Animal; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperkinesis; Male; Motor Activity; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Social Isolation; Thiazoles | 2012 |
Investigation of the antidyskinetic site of action of metabotropic and ionotropic glutamate receptor antagonists. Intracerebral infusions in 6-hydroxydopamine-lesioned rats with levodopa-induced dyskinesia.
Topics: Animals; Anti-Dyskinesia Agents; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Infusions, Intraventricular; Levodopa; Male; Oxidopamine; Phenols; Piperidines; Putamen; Quinoxalines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substantia Nigra; Subthalamic Nucleus; Thiazoles | 2012 |
The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent.
Topics: Animals; Antidepressive Agents; Citalopram; Diet; Excitatory Amino Acid Antagonists; Fenclonine; Fluoxetine; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Receptors, Kainic Acid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Thiazoles; Tryptophan | 2014 |
A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats.
Topics: Allosteric Regulation; Analysis of Variance; Animals; Binding, Competitive; Cocaine; Cues; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; HEK293 Cells; Humans; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Inhibitory Concentration 50; Male; Motor Activity; Nitriles; Piperidines; Pyridines; Random Allocation; Rats; Receptor, Metabotropic Glutamate 5; Reinforcement Schedule; Reward; Secondary Prevention; Self Administration; Sucrose; Thiazoles | 2014 |
Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition.
Topics: Animal Nutrition Sciences; Animals; Atrophy; Cell Proliferation; Disease Models, Animal; Down-Regulation; Epithelial Cells; Epithelium; Food; Glucagon-Like Peptide 2; Glutamic Acid; Intestinal Mucosa; Jejunum; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Parenteral Nutrition, Total; Permeability; Piperidines; Receptor, Metabotropic Glutamate 5; Receptors, G-Protein-Coupled; Signal Transduction; Thiazoles | 2014 |
Sympathetic β-adrenergic mechanism in pudendal inhibition of nociceptive and non-nociceptive reflex bladder activity.
Topics: Adrenergic beta-Antagonists; Animals; Cats; Denervation; Electric Stimulation; Female; Hypogastric Plexus; Male; Nociception; Piperidines; Propranolol; Pudendal Nerve; Rats; Receptors, Adrenergic, beta; Reflex; Thiazoles; Urinary Bladder | 2016 |
High-frequency stimulation-induced synaptic potentiation in dorsal and ventral CA1 hippocampal synapses: the involvement of NMDA receptors, mGluR5, and (L-type) voltage-gated calcium channels.
Topics: Animals; CA1 Region, Hippocampal; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Long-Term Potentiation; Male; Nimodipine; Piperazines; Piperidines; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Thiazoles | 2016 |
Selective Blockade of the Metabotropic Glutamate Receptor mGluR5 Protects Mouse Livers in In Vitro and Ex Vivo Models of Ischemia Reperfusion Injury.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Disease Models, Animal; Hepatocytes; Imidazoles; Liver; Mice; Mitochondria, Liver; Piperidines; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Reperfusion Injury; Thiazoles; Tumor Necrosis Factor-alpha | 2018 |
Synaptic Depotentiation and mGluR5 Activity in the Nucleus Accumbens Drive Cocaine-Primed Reinstatement of Place Preference.
Topics: Animals; Cocaine; Conditioning, Operant; Electrophysiological Phenomena; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Nucleus Accumbens; Optogenetics; Patch-Clamp Techniques; Piperidines; Receptors, AMPA; Receptors, Kainic Acid; Signal Transduction; Synaptic Potentials; Thiazoles | 2019 |
The role of glutamate mGlu5 and adenosine A2a receptor interactions in regulating working memory performance and persistent cocaine seeking in rats.
Topics: Adenosine A2 Receptor Antagonists; Animals; Cocaine-Related Disorders; Conditioning, Operant; Drug-Seeking Behavior; Male; Memory, Short-Term; Motor Activity; Piperidines; Psychomotor Performance; Purines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Metabotropic Glutamate 5; Recurrence; Self Administration; Thiazoles | 2020 |
Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease.
Topics: Animals; Axons; Calcium Signaling; Cells, Cultured; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Thiazoles | 2021 |