Page last updated: 2024-08-21

thiazoles and 1-methyl-4-phenylpyridinium

thiazoles has been researched along with 1-methyl-4-phenylpyridinium in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.00)18.2507
2000's16 (64.00)29.6817
2010's5 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boireau, A; Doble, A; Dubédat, P; Meunier, M; Miquet, JM1
Kitamura, Y; Kohno, Y; Nakazawa, M; Nomura, Y1
Bennett, JP; Cassarino, DS; Fall, CP; Smith, TS1
Kakimura, JI; Kitamura, Y; Kohno, Y; Kosaka, T; Matsuoka, Y; Nomura, Y; Taniguchi, T1
Abramova, NN; Bennett, JP; Cassarino, DS; Halvorsen, EM; Parker, WD; Sturgill, TW; Swerdlow, RH1
Ferger, B; Teismann, P1
Kakimura, J; Kitamura, Y; Kohno, Y; Nomura, Y; Takata, K; Taniguchi, T1
Abramova, NA; Bennett, JP; Cassarino, DS; Khan, SM; Painter, TW1
Borwege, S; Hagner, D; Joyce, JN; Millan, MJ; Osredkar, T; PazSoldan, M; Presgraves, S; Renish, L; Replogle, M1
Jang, MH; Kim, CJ; Kim, EH; Shin, MC; Shin, MS1
Lin, LF; Rubin, LL; Xu, M1
Borwege, S; Joyce, JN; Millan, MJ; Presgraves, SP1
Cooper, JM; Gu, M; Iravani, MM; Irvani, M; Jenner, P; King, D; Schapira, AH1
Hillard, CJ; Joseph, J; Kalyanaraman, B; Shang, T1
Barkats, M; Colin, P; Faucon-Biguet, N; Horellou, P; Mallet, J; Millecamps, S1
Duka, T; Sidhu, A1
Ali, HK; Ali, SF; Binienda, ZK; Duhart, HM; Fu, X; Patterson, TA; Paule, MG; Sadovova, N; Slikker, W; Virmani, A; Wang, C; Zou, X1
Liu, RG; Shang, Y; Sun, SG; Wu, Y; Yang, WQ1
Abe, K; Horiguchi, Y; Kitabatake, M; Ogawa, K; Saitoh, T; Taguchi, K; Yamashita, A1
Chuang, JI; Hong, YT; Huang, JY1
Chen, VT; Huang, CL; Huang, NK; Lee, YC; Liao, WC1
Kim, LW; Kim, YH; Lee, BJ; Lee, CH; Lee, JG; Park, SW; Shin, BS1
Chien, WL; Fu, WM; Hung, SY; Kang, KH; Lee, MJ; Lee, TR1
Lew, J; Liu, W; Szumlinski, KK; Zhang, L1
Lu, BX; Luo, YF; Man, RY; Wang, XF; Zeng, QG; Zeng, Y1

Other Studies

25 other study(ies) available for thiazoles and 1-methyl-4-phenylpyridinium

ArticleYear
Riluzole and experimental parkinsonism: partial antagonism of MPP(+)-induced increase in striatal extracellular dopamine in rats in vivo.
    Neuroreport, 1994, Oct-27, Volume: 5, Issue:16

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Excitatory Amino Acid Antagonists; Extracellular Space; Homovanillic Acid; Male; Parkinson Disease, Secondary; Rats; Riluzole; Thiazoles

1994
Inhibitory effects of talipexole and pramipexole on MPTP-induced dopamine reduction in the striatum of C57BL/6N mice.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Azepines; Benzothiazoles; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Agonists; Homovanillic Acid; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neostriatum; Pramipexole; Synaptosomes; Thiazoles

1997
Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Biological Transport; Calcium; Corpus Striatum; Dopamine Agents; Humans; Ion Channel Gating; Liver; Male; Microdialysis; Mitochondria; Neuroblastoma; Neuroprotective Agents; Neurotoxins; Parkinson Disease, Secondary; Phosphorus; Porins; Pramipexole; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiazoles; Tumor Cells, Cultured

1998
Protective effects of the antiparkinsonian drugs talipexole and pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic death in human neuroblastoma SH-SY5Y cells.
    Molecular pharmacology, 1998, Volume: 54, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Antiparkinson Agents; Apoptosis; Azepines; Benzothiazoles; Bromocriptine; Bucladesine; Caspase 3; Caspases; Dopamine Agonists; Humans; Pramipexole; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1998
Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease.
    Journal of neurochemistry, 2000, Volume: 74, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Adenine Nucleotides; Benzothiazoles; Electron Transport; Enzyme Activation; Free Radical Scavengers; Herbicides; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Mitochondria; Mitogen-Activated Protein Kinases; Neuroblastoma; Neurons; NF-kappa B; Oxidative Stress; Parkinson Disease; Peptides; Pramipexole; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Signal Transduction; Superoxide Dismutase; Thiazoles; Tumor Cells, Cultured

2000
Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease.
    Synapse (New York, N.Y.), 2001, Volume: 39, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Count; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Dopamine; Homovanillic Acid; Isoenzymes; Male; Meloxicam; Membrane Proteins; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Neuroprotective Agents; Parkinsonian Disorders; Prostaglandin-Endoperoxide Synthases; Substantia Nigra; Thiazines; Thiazoles; Tyrosine 3-Monooxygenase

2001
Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole.
    European journal of pharmacology, 2001, Apr-06, Volume: 417, Issue:1-2

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Antiparkinson Agents; Azepines; Benzothiazoles; Caspases; Cell-Free System; Cytochrome c Group; Cytosol; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Nerve Tissue Proteins; Organelles; Pramipexole; Synucleins; Thiazoles; Tumor Cells, Cultured

2001
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma.
    Journal of neuroscience research, 2002, Feb-15, Volume: 67, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Alzheimer Disease; Amyloid beta-Peptides; Anti-Bacterial Agents; Aristolochic Acids; Benzothiazoles; Bongkrekic Acid; Brain; Caspase Inhibitors; Caspases; Cell Death; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Humans; Neuroblastoma; Neurodegenerative Diseases; Neurons; Parkinson Disease; Peptide Fragments; Phenanthrenes; Pramipexole; Thiazoles; Tumor Cells, Cultured

2002
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Cell Count; Cell Line; DNA; Dopamine Agents; Dopamine Agonists; Humans; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrazolium Salts; Thiazoles

2003
Protective effect of aqueous extract of Ginseng radix against 1-methyl-4-phenylpyridinium-induced apoptosis in PC12 cells.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:12

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Shape; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Genes, p53; Neurons; Panax; PC12 Cells; Plant Extracts; Plant Roots; Plants, Medicinal; Proto-Oncogene Proteins c-bcl-2; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Suppressor Protein p53; Water

2003
A non-peptidyl neurotrophic small molecule for midbrain dopaminergic neurons.
    Journal of neurochemistry, 2004, Volume: 89, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Astrocytes; Cell Count; Cell Survival; Cells, Cultured; Colforsin; Dopamine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glial Cell Line-Derived Neurotrophic Factor; Mesencephalon; Nerve Growth Factors; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Sensitivity and Specificity; Serotonin; Sulfonamides; Thiazoles; Tyrosine 3-Monooxygenase

2004
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.
    Experimental neurology, 2004, Volume: 190, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Antibodies; Benzothiazoles; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Humans; Neuroblastoma; Neurons; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetradecanoylphorbol Acetate; Thiazoles; Tretinoin

2004
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.
    Journal of neurochemistry, 2004, Volume: 91, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antioxidants; Benzothiazoles; Carbocyanines; Caspase 3; Caspases; Cell Count; Cell Death; Cell Line, Tumor; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Drug Interactions; Flow Cytometry; Humans; Jurkat Cells; L-Lactate Dehydrogenase; Mitochondria; Necrosis; Neuroblastoma; Pramipexole; Rotenone; Thiazoles

2004
Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death.
    The Journal of biological chemistry, 2005, Oct-14, Volume: 280, Issue:41

    Topics: 1-Methyl-4-phenylpyridinium; Aconitate Hydratase; Antimycin A; Antioxidants; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cell Line, Tumor; Death-Associated Protein Kinases; Electron Transport; Humans; Lysosomes; Membrane Potentials; Microscopy, Electron; Mitochondrial Membranes; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphorylation; Rotenone; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Time Factors; Toxins, Biological

2005
1-methyl-4-phenylpyridinium neurotoxicity is attenuated by adenoviral gene transfer of human Cu/Zn superoxide dismutase.
    Journal of neuroscience research, 2006, Feb-01, Volume: 83, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Count; Cell Line, Tumor; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Motor Activity; Neuroblastoma; Neurotoxicity Syndromes; Parkinson Disease; Rats; Rotarod Performance Test; Substantia Nigra; Superoxide Dismutase; Tetrazolium Salts; Thiazoles; Transgenes; Tyrosine 3-Monooxygenase

2006
The neurotoxin, MPP+, induces hyperphosphorylation of Tau, in the presence of alpha-Synuclein, in SH-SY5Y neuroblastoma cells.
    Neurotoxicity research, 2006, Volume: 10, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; alpha-Synuclein; Blotting, Western; Cell Fractionation; Cell Line, Tumor; Cell Survival; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression; Humans; Neuroblastoma; Neurotoxins; Phosphorylation; Serine; tau Proteins; Tetrazolium Salts; Thiazoles; Transfection

2006
L-carnitine protects neurons from 1-methyl-4-phenylpyridinium-induced neuronal apoptosis in rat forebrain culture.
    Neuroscience, 2007, Jan-05, Volume: 144, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Carnitine; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Prosencephalon; Rats; Rats, Sprague-Dawley; Sialic Acids; Tetrazolium Salts; Thiazoles

2007
Protective effect of erythropoietin against 1-methyl-4-phenylpyridinium-induced neurodegenaration in PC12 cells.
    Neuroscience bulletin, 2007, Volume: 23, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Erythropoietin; Flow Cytometry; Herbicides; In Situ Nick-End Labeling; Membrane Potential, Mitochondrial; Neuroprotective Agents; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2007
Synthesis of chiral 3-methyl- and 3-methyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline and prevention of MPP+ -induced cytotoxicity.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2008, Volume: 4, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Death; Data Interpretation, Statistical; Dopamine Agents; Dopamine Antagonists; Models, Molecular; PC12 Cells; Rats; Stereoisomerism; Structure-Activity Relationship; Tetrahydroisoquinolines; Tetrazolium Salts; Thiazoles

2008
Fibroblast growth factor 9 prevents MPP+-induced death of dopaminergic neurons and is involved in melatonin neuroprotection in vivo and in vitro.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Antibodies; Cell Death; Dopamine; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 9; Fibroblast Growth Factors; Glial Fibrillary Acidic Protein; Herbicides; Male; Melatonin; Mesencephalon; Microtubule-Associated Proteins; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase

2009
The roles of the thioredoxin system and peroxiredoxins in 1-methyl-4-phenyl-pyridinium ion-induced cytotoxicity in rat pheochromocytoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Lipid Peroxidation; Membrane Potential, Mitochondrial; Oxidation-Reduction; PC12 Cells; Peroxiredoxins; Pheochromocytoma; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Superoxides; Tetrazolium Salts; Thiazoles; Thioredoxins; Tumor Stem Cell Assay

2010
Protective effects of atypical antipsychotic drugs against MPP(+)-induced oxidative stress in PC12 cells.
    Neuroscience research, 2011, Volume: 69, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Antipsychotic Agents; Aripiprazole; bcl-2-Associated X Protein; Benzodiazepines; Blotting, Western; Cell Survival; Haloperidol; Herbicides; Olanzapine; Oxidative Stress; PC12 Cells; Piperazines; Quinolones; Rats; Reactive Oxygen Species; Superoxide Dismutase; Thiazoles

2011
Impairment of oxidative stress-induced heme oxygenase-1 expression by the defect of Parkinson-related gene of PINK1.
    Journal of neurochemistry, 2011, Volume: 117, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Adenoviridae; Benzimidazoles; Blotting, Western; Cell Line; Cell Survival; Cloning, Molecular; Coloring Agents; Dopamine; Fluorescent Antibody Technique; Fluorescent Dyes; Gene Expression Regulation; Genetic Vectors; Heme Oxygenase-1; HSP90 Heat-Shock Proteins; Humans; L-Lactate Dehydrogenase; Mutation; Oxidative Stress; Parkinson Disease, Secondary; Protein Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazolium Salts; Thiazoles

2011
p10, the N-terminal domain of p35, protects against CDK5/p25-induced neurotoxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Dec-04, Volume: 109, Issue:49

    Topics: 1-Methyl-4-phenylpyridinium; Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Cycle Proteins; Cell Survival; Chlorocebus aethiops; Chromobox Protein Homolog 5; COS Cells; Cyclin-Dependent Kinase 5; Immunohistochemistry; Microscopy, Fluorescence; Nerve Tissue Proteins; Neurons; Peptide Fragments; Peptides; Peroxiredoxins; Phosphorylation; Proteolysis; Rats; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles

2012
Induction of GADD45α protects M17 neuroblastoma cells against MPP*.
    IUBMB life, 2014, Volume: 66, Issue:11

    Topics: 1-Methyl-4-phenylpyridinium; Analysis of Variance; Anthracenes; Blotting, Western; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Imidazoles; In Situ Nick-End Labeling; Nuclear Proteins; Parkinson Disease; Pyridines; Real-Time Polymerase Chain Reaction; RNA Interference; Tetrazolium Salts; Thiazoles

2014