Page last updated: 2024-08-21

thiazoles and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

thiazoles has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's10 (47.62)29.6817
2010's5 (23.81)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Colpaert, FC; Degryse, AD; Van Craenendonck, HV1
Boireau, A; Bordier, F; Doble, A; Dubédat, P; Durand, G; Meunier, M; Miquet, JM; Peny, C1
Barnéoud, P; Boireau, A; Doble, A; Dubédat, P; Mazadier, M; Miquet, JM; Parmentier, S1
Kitamura, Y; Kohno, Y; Nakazawa, M; Nomura, Y1
Domino, EF; Kohno, Y; Ni, L; Sasa, M; Zhang, H1
Appel, SH; He, Y; Jankovic, J; Le, W; Xu, J; Zou, L1
Archer, T; Fredriksson, A; Palomo, T1
Anderson, DW; Neavin, T; Schneider, JS; Smith, JA1
Giardiniere, M; Morain, P; Schneider, JS1
Breidert, T; Callebert, J; Heneka, MT; Hirsch, EC; Landreth, G; Launay, JM1
Cadet, JL; Cutler, RG; Duan, W; Greig, NH; Guo, Z; Ladenheim, B; Mattson, MP; Oyler, J; Yu, QS; Zhu, X1
Borwege, S; Hagner, D; Joyce, JN; Millan, MJ; Osredkar, T; PazSoldan, M; Presgraves, S; Renish, L; Replogle, M1
Gorman, AM; Quigney, DJ; Samali, A1
Cooper, JM; Haddon, CO; Iravani, MM; Jenner, P; Schapira, AH1
Bi, J; Jiang, B; Zhang, H; Zhang, XL1
Asari, M; Iida, S; Matsubara, K; Ohkubo, T; Omura, T; Sakaguchi, T; Shimizu, K; Suno, M; Tasaki, Y; Yamada, T1
Alagille, D; Bogenpohl, JW; Delevich, K; Masilamoni, GJ; Smith, Y; Tamagnan, G; Votaw, JR; Wichmann, T1
Asari, M; Awaya, T; Kimura, N; Matsubara, K; Noda, T; Ohkubo, T; Ohtaki, K; Omura, T; Ono, T; Sakaguchi, T; Shimizu, K; Suno, M; Tasaki, Y; Yamamoto, J1
Aron Badin, R; Auguet, M; Bertrand, A; Boulet, S; Brouillet, E; Chabrier, PE; Dollé, F; Gaillard, MC; Guillermier, M; Hantraye, P; Jan, C; Malgorn, C; Savasta, M; Spinnewyn, B; Van Camp, N1
Di Paolo, T; Morissette, M; Parent, M; Riahi, G; Samadi, P1
Demir-Dora, D; Goksu Erol, AY; Kocanci, FG; Uysal, H1

Other Studies

21 other study(ies) available for thiazoles and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Effects of an alpha 2 antagonist in a 20-year-old Java monkey with MPTP-induced parkinsonian signs.
    Brain research bulletin, 1991, Volume: 26, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic alpha-Antagonists; Animals; Blinking; Locus Coeruleus; Macaca fascicularis; Neurons; Parkinson Disease, Secondary; Piperidines; Thiazoles; Tremor

1991
Riluzole and experimental parkinsonism: antagonism of MPTP-induced decrease in central dopamine levels in mice.
    Neuroreport, 1994, Dec-20, Volume: 5, Issue:18

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Riluzole; Thiazoles

1994
Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat.
    Neuroscience, 1996, Volume: 74, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Central Nervous System Stimulants; Conditioning, Operant; Dopamine Agonists; Female; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Riluzole; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Thiazoles

1996
Inhibitory effects of talipexole and pramipexole on MPTP-induced dopamine reduction in the striatum of C57BL/6N mice.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Azepines; Benzothiazoles; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Agonists; Homovanillic Acid; In Vitro Techniques; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Neostriatum; Pramipexole; Synaptosomes; Thiazoles

1997
Effects of pramipexole on contraversive rotation and functional motor impairments in 1-methyl-4-phenyl1,2,3, 6-tetrahydropyridine-induced chronic hemiparkinsonian monkeys.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Benzothiazoles; Dopamine Agents; Dose-Response Relationship, Drug; Eating; Female; Macaca nemestrina; Motor Activity; Parkinson Disease, Secondary; Pramipexole; Rotation; Stereotyped Behavior; Thiazoles; Volition

1998
Pramipexole inhibits lipid peroxidation and reduces injury in the substantia nigra induced by the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice.
    Neuroscience letters, 2000, Mar-10, Volume: 281, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzothiazoles; Dopamine; Dopamine Agents; Dopamine Agonists; Free Radical Scavengers; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Pramipexole; Substantia Nigra; Thiazoles; Thiobarbituric Acid Reactive Substances; Tyrosine 3-Monooxygenase

2000
Effects of MAO inhibitors upon MPTP mice chronically treated with suprathreshold doses of L-dopa.
    Behavioural pharmacology, 2000, Volume: 11, Issue:7-8

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Clorgyline; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Levodopa; Locomotion; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Motor Activity; Phenelzine; Phenethylamines; Selegiline; Thiazoles; Tryptamines

2000
Neuroprotective effects of pramipexole in young and aged MPTP-treated mice.
    Brain research, 2001, Jun-29, Volume: 905, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Antiparkinson Agents; Benzothiazoles; Cell Survival; Dopamine; Dopamine Agents; Fluorescent Dyes; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neural Pathways; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Pramipexole; Stilbamidines; Substantia Nigra; Thiazoles; Tyrosine 3-Monooxygenase

2001
Effects of the prolyl endopeptidase inhibitor S 17092 on cognitive deficits in chronic low dose MPTP-treated monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 26, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cognition Disorders; Conditioning, Operant; Discrimination Learning; Dopamine Agents; Indoles; Macaca fascicularis; Male; Parkinson Disease, Secondary; Pattern Recognition, Visual; Prolyl Oligopeptidases; Psychomotor Performance; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazoles; Thiazolidines

2002
Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.
    Journal of neurochemistry, 2002, Volume: 82, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Cell Count; Cell Survival; Corpus Striatum; Disease Models, Animal; Dopamine; Homovanillic Acid; Hypoglycemic Agents; Immunohistochemistry; Macrophage-1 Antigen; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Parkinsonian Disorders; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Substantia Nigra; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine 3-Monooxygenase

2002
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.
    Annals of neurology, 2002, Volume: 52, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apoptosis; bcl-2-Associated X Protein; Behavior, Animal; Benzothiazoles; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Neuroprotective Agents; Parkinsonian Disorders; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Thiazoles; Toluene; Tumor Suppressor Protein p53

2002
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Benzothiazoles; Cell Count; Cell Line; DNA; Dopamine Agents; Dopamine Agonists; Humans; Immunohistochemistry; Indoles; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrazolium Salts; Thiazoles

2003
Heat shock protects PC12 cells against MPP+ toxicity.
    Brain research, 2003, Dec-12, Volume: 993, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Blotting, Western; Cell Death; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Fluorescent Dyes; Heat-Shock Proteins; Hot Temperature; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; MPTP Poisoning; Neoplasm Proteins; Oligopeptides; PC12 Cells; Rats; Shock; Tetrazolium Salts; Thiazoles

2003
Pramipexole protects against MPTP toxicity in non-human primates.
    Journal of neurochemistry, 2006, Volume: 96, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antioxidants; Benzothiazoles; Callithrix; Cell Count; Corpus Striatum; Disease Models, Animal; Drug Administration Schedule; Female; Immunohistochemistry; Male; MPTP Poisoning; Pramipexole; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase

2006
Neuroprotective activities of catalpol on MPP+/MPTP-induced neurotoxicity.
    Neurological research, 2008, Volume: 30, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Cell Survival; Dopamine; Dose-Response Relationship, Drug; Glucosides; Iridoid Glucosides; Iridoids; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; PC12 Cells; Rats; Tetrazolium Salts; Thiazoles; Time Factors; Tyrosine 3-Monooxygenase

2008
Meloxicam protects cell damage from 1-methyl-4-phenyl pyridinium toxicity via the phosphatidylinositol 3-kinase/Akt pathway in human dopaminergic neuroblastoma SH-SY5Y cells.
    Brain research, 2010, Jul-16, Volume: 1344

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line, Tumor; Dopamine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Meloxicam; Neuroblastoma; Neurotoxins; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinase; Signal Transduction; Thiazines; Thiazoles; Time Factors

2010
Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys.
    Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Brain; Brain Mapping; Calbindins; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Fluorine Radioisotopes; Macaca mulatta; MPTP Poisoning; Nerve Degeneration; Neurons; Norepinephrine; Nortropanes; Positron-Emission Tomography; Protein Binding; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; S100 Calcium Binding Protein G; Thiazoles; Tyrosine 3-Monooxygenase

2011
Meloxicam ameliorates motor dysfunction and dopaminergic neurodegeneration by maintaining Akt-signaling in a mouse Parkinson's disease model.
    Neuroscience letters, 2012, Jul-11, Volume: 521, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Hypokinesia; Male; Meloxicam; Mesencephalon; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroprotective Agents; Parkinson Disease; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Thiazines; Thiazoles; Tyrosine 3-Monooxygenase

2012
IRC-082451, a novel multitargeting molecule, reduces L-DOPA-induced dyskinesias in MPTP Parkinsonian primates.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Antioxidants; Antiparkinson Agents; Behavior, Animal; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Disease Models, Animal; Dopamine Agents; Dyskinesias; Immunohistochemistry; Levodopa; Macaca fascicularis; Magnetic Resonance Imaging; Male; Neurons; Oxidative Stress; Parkinson Disease; Positron-Emission Tomography; Thiazoles

2013
Basal ganglia serotonin 1B receptors in parkinsonian monkeys with L-DOPA-induced dyskinesia.
    Biochemical pharmacology, 2013, Oct-01, Volume: 86, Issue:7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Benzamides; Brain; Case-Control Studies; Dyskinesia, Drug-Induced; Levodopa; Macaca fascicularis; Parkinson Disease; Pyridines; Receptor, Serotonin, 5-HT1B; Serotonin; Sulfonamides; Thiazoles

2013
Additive cell protective and oxidative stress reducing effects of combined treatment with cromolyn sodium and masitinib on MPTP-induced toxicity in SH-SY5Y neuroblastoma cells.
    Chemico-biological interactions, 2022, Feb-25, Volume: 354

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Benzamides; Cell Line, Tumor; Cromolyn Sodium; Cytoprotection; Humans; Oxidative Stress; Piperidines; Pyridines; Thiazoles

2022