thiazole-4-carboxamide adenine dinucleotide has been researched along with tiazofurin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Labello, NP; Olesiak, M; Pankiewicz, KW; Petrelli, R; Wilson, DJ | 1 |
| Goldstein, BM; Li, H | 1 |
| Jayaram, HN; Weber, G; Zhen, W | 2 |
| Cooney, DA; Goldstein, BM; Jayaram, HN; Marquez, VE; Weber, G; Zhen, W | 1 |
| Eble, JN; Hoffman, R; Jayaram, HN; Nagai, M; Natsumeda, Y; Paulik, E; Tricot, G; Weber, G; Zhen, WN | 1 |
| Goto, H; Ogasawara, N; Yamada, Y; Yoshino, M | 1 |
| Bell, JE; Goldstein, BM; Marquez, VE | 1 |
| Natsumeda, Y; Pillwein, K; Weber, G | 1 |
| Hoffman, R; Jayaram, HN; Natsumeda, Y; Tricot, GJ; Weber, G; Yamada, Y; Yamaji, Y | 1 |
| Ahluwalia, GS; Carney, DN; Cooney, DA; Jayaram, HN; Johns, DG | 1 |
| Ahluwalia, GS; Cooney, DA; Jayaram, HN; Johns, DG; Marquez, VE | 1 |
| Hoffman, R; Jayaram, HN; Nichols, CR; Pillwein, K; Weber, G | 1 |
| Jayaram, HN | 1 |
| Ahluwalia, GS; Cooney, DA; Jayaram, HN; Johns, DG; Plowman, JP | 1 |
| Gharehbaghi, K; Jayaram, HN; Zhen, W | 1 |
| Dacevic, M; Jokanovic, M; Mandic, L; Pejanovic, V; Piperski, V; Ristic, S; Tasic, J | 1 |
1 trial(s) available for thiazole-4-carboxamide adenine dinucleotide and tiazofurin
| Article | Year |
|---|---|
Tiazofurin down-regulates expression of c-Ki-ras oncogene in a leukemic patient.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Blast Crisis; Blotting, Northern; Down-Regulation; Gene Expression Regulation; Genes, ras; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Pilot Projects; Ribavirin; RNA; Uric Acid | 1991 |
16 other study(ies) available for thiazole-4-carboxamide adenine dinucleotide and tiazofurin
| Article | Year |
|---|---|
Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.
Topics: Adenine Nucleotides; Combinatorial Chemistry Techniques; Humans; IMP Dehydrogenase; Models, Molecular; Molecular Structure; Mycophenolic Acid; Structure-Activity Relationship; Sulfonamides | 2008 |
Carboxamide group conformation in the nicotinamide and thiazole-4-carboxamide rings: implications for enzyme binding.
Topics: Adenine Nucleotides; Amides; Antineoplastic Agents; Crystallography; Enzyme Inhibitors; IMP Dehydrogenase; Molecular Conformation; NADP; Niacinamide; Ribavirin; Stereoisomerism; Structure-Activity Relationship | 1992 |
Antitumor activity of tiazofurin in human colon carcinoma HT-29.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Male; Mice; Mice, Nude; Ribavirin; Tumor Cells, Cultured | 1992 |
Cytotoxicity of tiazofurin and its arabinose and xylose analogues in K562 cells.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Arabinonucleosides; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; IMP Dehydrogenase; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nucleosides; Ribavirin | 1991 |
IMP dehydrogenase and action of antimetabolites in human cultured blast cells.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Humans; IMP Dehydrogenase; Inosine Monophosphate; Ketone Oxidoreductases; Kinetics; Leukemia; NAD; Ribavirin; Ribonucleosides | 1990 |
Dehydrogenase binding by tiazofurin anabolites.
Topics: Adenine Nucleotides; Antineoplastic Agents; Binding, Competitive; Computer Simulation; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Models, Chemical; Oxidoreductases; Ribavirin; Ribonucleosides | 1990 |
Determination of thiazole-4-carboxamide adenine dinucleotide (TAD) levels in mononuclear cells of leukemic patients treated with tiazofurin.
Topics: Adenine Nucleotides; Antineoplastic Agents; Chromatography, High Pressure Liquid; Guanosine Triphosphate; Humans; Leukemia; Monocytes; Reproducibility of Results; Ribavirin; Sensitivity and Specificity | 1991 |
Targets and markers of selective action of tiazofurin.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Guanine Nucleotides; IMP Dehydrogenase; Liver; Liver Neoplasms, Experimental; NAD; Phosphoribosyl Pyrophosphate; Rats; Rats, Inbred Strains; Ribavirin; Ribonucleosides | 1985 |
IMP dehydrogenase: inhibition by the anti-leukemic drug, tiazofurin.
Topics: Adenine Nucleotides; Antineoplastic Agents; Blast Crisis; Female; Humans; IMP Dehydrogenase; Ketone Oxidoreductases; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; NADP; Ribavirin; Ribonucleosides | 1989 |
Relationships between the cytotoxicity of tiazofurin and its metabolism by cultured human lung cancer cells.
Topics: Adenine Nucleotides; Antineoplastic Agents; Cell Line; Cells, Cultured; Cytotoxicity Tests, Immunologic; Humans; IMP Dehydrogenase; Lung Neoplasms; Purine Nucleotides; Pyrimidine Nucleotides; Ribavirin; Ribonucleosides; Sepharose; Tumor Stem Cell Assay | 1985 |
Studies on the mechanism of action of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide). VI. Biochemical and pharmacological studies on the degradation of thiazole-4-carboxamide adenine dinucleotide (TAD).
Topics: Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Colonic Neoplasms; IMP Dehydrogenase; Leukemia P388; Male; Mice; Phosphoric Diester Hydrolases; Ribavirin; Ribonucleosides | 1986 |
Selective sensitivity to tiazofurin of human leukemic cells.
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Agents; Female; Guanosine Triphosphate; Humans; Leukemia; Leukocytes; Male; Middle Aged; Ribavirin; Ribonucleosides | 1986 |
Biochemical mechanisms of resistance to tiazofurin.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Drug Resistance; Guanine Nucleotides; Humans; Inosine Nucleotides; Leukemia L1210; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Ribavirin; Ribonucleosides | 1985 |
Studies on the mechanism of action of 2-beta-D-ribofuranosylthiazole-4-carboxamide--V. Factors governing the response of murine tumors to tiazofurin.
Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Biotransformation; Dose-Response Relationship, Drug; Drug Resistance; Female; IMP Dehydrogenase; Male; Mice; Neoplasms, Experimental; Nucleotides; Ribavirin; Ribonucleosides | 1984 |
Biochemical consequences of resistance to tiazofurin in human myelogenous leukemic K562 cells.
Topics: Adenine Nucleotides; Antineoplastic Agents; Biological Transport; Carbon Radioisotopes; Deoxyribonucleotides; Drug Resistance; Drug Screening Assays, Antitumor; Guanine; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Nicotinamide-Nucleotide Adenylyltransferase; Nucleic Acids; Phosphoric Diester Hydrolases; Phosphorylation; Purine Nucleotides; Ribavirin; Tumor Cells, Cultured | 1993 |
Simultaneous LC determination of tiazofurin, its acetyl and benzoyl esters and their active metabolite thiazole-4-carboxamide adenine dinucleotide in biological samples.
Topics: Adenine Nucleotides; Animals; Chromatography, High Pressure Liquid; Esters; Rats; Ribavirin; Tumor Cells, Cultured | 2002 |