thiamine pyrophosphate and thioctic acid

thiamine pyrophosphate has been researched along with thioctic acid in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199035 (87.50)18.7374
1990's3 (7.50)18.2507
2000's1 (2.50)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bridges, BJ; Cooper, RH; Denton, RM; Randle, PJ; Walsh, DA1
Alonso, D; Chacin, J; Cornfield, D; Harris, JB; Park, OH1
Borges, A; Dardel, F; Graham, LD; Hawkins, CF; Laue, ED; Packman, LC; Perham, RN1
Burlev, VA; Mamedalieva, NM; Sidel'nikova, VM1
Flournoy, DS; Frey, PA2
Orme-Johnson, WH; Wahl, RC1
Rajacic, Z; Thölen, H; Zimmerli, W1
Colombi, A; Engelhart, G; Thölen, H1
Barbier, P; Caroli, J; Hecht, Y1
Bigler, F; Colombi, A; Duckert, F; Huber, F; Müller, HR; Thölen, H1
Benhamou, JP; Caroli, J; Debray, C; Gaultier, M; Leger, L1
Colombi, A; Huber, F; Thölen, H1
Bani, G1
Poulsen, LL; Wedding, RT1
Rozanov, AIa1
Ziegler, K1
Elsas, LJ; Pask, BA; Perl, DP; Truster, S; Wheeler, FB1
Koike, M1
Frey, PA; Maldonado, ME; Oh, KJ1
Ilinich, VK; Plastun, FF1
Mach, B; Mossor-Ostrowska, J; Wilkoń, B1
Bauman, N; Hill, CJ1
Lujf, A; Moser, K1
Black, MK; Wedding, RT1
Bognel, JC; Caroli, J; Hecht, Y; Lauga, J; Rautureau, M; Thölen, H1
Craig, DW; Wedding, RT1
Frey, PA1
Kuz'menko, SA; Lokaĭ, AI; Smorshchok, SA; Volkov, KS1
Jordan, F1
Andersson, LA; Baker, JC; Cole, AB; Gong, X; Li, L; Liu, S; Peng, T; Ravindran, S; Robben, PM; Roche, TE; Yan, X1
FRASCARIA, F1
BALESTRERI, R; FAZIO, B; MORGANO, G1
OTANI, M1
MOR, F1
FAHMY, AR; IBRAHIM, HH; TALAAT, M1
CORREIA, JA; da COSTA, S; da SILVA, J; MALDONADO, FE1
AIZAWA, T; HASEGAWA, T; HORI, S; KATO, M; KOJIMA, K; MORI, K; NAGANO, S; NAKAMURA, H; YOSHIDA, K1
FERRITO, A; GOLDNER, R; PRIMAVESI, L1
Feichtinger, RG; Fleuren, L; Freisinger, P; Haack, TB; Koch, J; Mayr, JA; Prokisch, H; Ribes, A; Rivera, I; Rodenburg, RJ; Smeitink, JA; Sperl, W; Zimmermann, FA1

Reviews

6 review(s) available for thiamine pyrophosphate and thioctic acid

ArticleYear
The lipoyl domain and its role in thiamin diphosphate-dependent oxidative decarboxylation.
    Journal of nutritional science and vitaminology, 1992, Volume: Spec No

    Topics: Binding Sites; Decarboxylation; Molecular Structure; Oxidation-Reduction; Protein Structure, Secondary; Thiamine Pyrophosphate; Thioctic Acid

1992
[Structure and function of enzyme complexes--with special reference to alpha-ketoacid dehydrogenase complexes of the pig heart muscle].
    Seikagaku. The Journal of Japanese Biochemical Society, 1972, Volume: 44, Issue:2

    Topics: Acyltransferases; Animals; Dihydrolipoamide Dehydrogenase; Flavin-Adenine Dinucleotide; Keto Acids; Microscopy, Electron; Models, Structural; Molecular Weight; Myocardium; Nucleotides; Oxidoreductases; Protein Conformation; Pyruvate Oxidase; Swine; Thiamine Pyrophosphate; Thioctic Acid

1972
[Treatment of acute hepatic insufficiency (a survey of the literature)].
    Voenno-meditsinskii zhurnal, 1972, Volume: 12

    Topics: Acute Disease; Adenosine Triphosphate; Arginine; Chemical and Drug Induced Liver Injury; Exchange Transfusion, Whole Blood; Folic Acid; Gastrointestinal Hemorrhage; Glutamine; Hepatic Encephalopathy; Humans; Hyperkalemia; Liver; Liver Diseases; Potassium Chloride; Radiation Injuries; Spironolactone; Thiamine Pyrophosphate; Thioctic Acid

1972
Mechanism of coupled electron and group transfer in Escherichia coli pyruvate dehydrogenase.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Acetyl Coenzyme A; Acetylation; Binding Sites; Chemical Phenomena; Chemistry; Coenzyme A; Electron Transport; Escherichia coli; Flavin-Adenine Dinucleotide; Molecular Weight; NAD; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Spectrophotometry; Thiamine Pyrophosphate; Thioctic Acid

1982
Interplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids.
    FEBS letters, 1999, Sep-03, Volume: 457, Issue:3

    Topics: Acetoin Dehydrogenase; Acetyl Coenzyme A; Amines; Coenzymes; Decarboxylation; Flavins; Oxidation-Reduction; Protons; Pyruvate Decarboxylase; Pyruvate Oxidase; Thiamine Pyrophosphate; Thioctic Acid

1999
The spectrum of pyruvate oxidation defects in the diagnosis of mitochondrial disorders.
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:3

    Topics: Energy Metabolism; Female; Humans; Iron-Sulfur Proteins; Male; Oxidation-Reduction; Pyruvate Dehydrogenase Complex; Pyruvate Dehydrogenase Complex Deficiency Disease; Thiamine Pyrophosphate; Thioctic Acid

2015

Trials

1 trial(s) available for thiamine pyrophosphate and thioctic acid

ArticleYear
[Influence of coenzyme A, nicotinamide adenine dinucleotide (NAD), alpha-lipoic acid and cocarboxylase on acute hepatitis (double blind experiment)].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1969, Volume: 2, Issue:2

    Topics: Adenosine Triphosphate; Alanine Transaminase; Alkaline Phosphatase; Ammonia; Aspartate Aminotransferases; Bilirubin; Blood Coagulation Factors; Blood Proteins; Clinical Trials as Topic; Coenzyme A; Glucose; Glycols; Hepatitis A; Humans; Ketones; Lactates; NAD; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1969

Other Studies

33 other study(ies) available for thiamine pyrophosphate and thioctic acid

ArticleYear
The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation.
    The Biochemical journal, 1976, Jul-01, Volume: 157, Issue:1

    Topics: Acetaldehyde; Adenylyl Imidodiphosphate; Animals; Arsenic; Coenzyme A; Diphosphates; Edetic Acid; Guanosine Triphosphate; Kinetics; Myocardium; NAD; Pyruvate Dehydrogenase Complex; Thiamine Pyrophosphate; Thioctic Acid

1976
Lipoate effect on carbohydrate and lipid metabolism and gastric H+ secretion.
    The American journal of physiology, 1975, Volume: 228, Issue:3

    Topics: Animals; Butyrates; Decanoic Acids; Fatty Acids; Gastric Juice; Gastric Mucosa; Glucose; Glycogen; Histamine; In Vitro Techniques; Lactates; Lipid Metabolism; Oxygen Consumption; Palmitic Acids; Propionates; Pyruvates; Rana catesbeiana; Stimulation, Chemical; Thiamine; Thiamine Pyrophosphate; Thioctic Acid; Triglycerides

1975
[Acid-base equilibrium and blood gases in pregnant women with habitual abortion after metabolic therapy].
    Akusherstvo i ginekologiia, 1992, Issue:2

    Topics: Abortion, Habitual; Acid-Base Equilibrium; Acidosis; Adult; Carbon Dioxide; Drug Combinations; Drug Therapy, Combination; Female; Humans; Oxygen; Pregnancy; Thiamine Pyrophosphate; Thioctic Acid; Vitamin A; Vitamin E

1992
Inactivation of the pyruvate dehydrogenase complex of Escherichia coli by fluoropyruvate.
    Biochemistry, 1989, Dec-12, Volume: 28, Issue:25

    Topics: Catalysis; Cysteine; Escherichia coli; Kinetics; Pyruvate Dehydrogenase Complex; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1989
Clostridial pyruvate oxidoreductase and the pyruvate-oxidizing enzyme specific to nitrogen fixation in Klebsiella pneumoniae are similar enzymes.
    The Journal of biological chemistry, 1987, Aug-05, Volume: 262, Issue:22

    Topics: Acetylene; Clostridium; Cysteine; Drug Stability; Electron Spin Resonance Spectroscopy; Electron Transport; Flavins; Flavodoxin; Iron; Ketone Oxidoreductases; Klebsiella pneumoniae; Nitrogen Fixation; Nitrogenase; Oxidation-Reduction; Protein Denaturation; Pyruvate Synthase; Spectrophotometry; Sulfur; Thiamine Pyrophosphate; Thioctic Acid

1987
Pyruvate dehydrogenase and 3-fluoropyruvate: chemical competence of 2-acetylthiamin pyrophosphate as an acetyl group donor to dihydrolipoamide.
    Biochemistry, 1986, Oct-07, Volume: 25, Issue:20

    Topics: Carbon Radioisotopes; Kinetics; Protein Binding; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1986
Effect of coenzyme-A, NAD, alpha lipoic-acid and cocarboxylase on survival of rats with galactosamine-induced severe hepatitis.
    Experientia, 1985, Aug-15, Volume: 41, Issue:8

    Topics: Animals; Coenzyme A; Disease Models, Animal; Female; Galactosamine; Hepatitis; Liver Function Tests; NAD; Rats; Rats, Inbred Strains; Thiamine Pyrophosphate; Thioctic Acid

1985
[Treatment of endogenic hepatic coma by coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase].
    Revue medico-chirurgicale des maladies du foie, 1966, Volume: 41, Issue:1

    Topics: Coenzyme A; Hepatic Encephalopathy; Humans; NAD; Thiamine Pyrophosphate; Thioctic Acid

1966
[Coenzyme treatment of severe jaundice due to hepatitis (Thölen's method)].
    Rein et foie, maladies de la nutrition; actualites, 1967, Volume: 10

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Coenzyme A; Coenzymes; Female; Hepatic Encephalopathy; Hepatitis; Humans; Injections, Intravenous; Jaundice; Middle Aged; NAD; Thiamine Pyrophosphate; Thioctic Acid

1967
Effects of a treatment with coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase on endogenous hepatic coma.
    Helvetica medica acta, 1967, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Ammonia; Bilirubin; Biopsy; Blood Coagulation Factors; Blood Coagulation Tests; Blood Protein Electrophoresis; Coenzyme A; Electroencephalography; Enzymes; Female; Hepatic Encephalopathy; Humans; Iron; Lactates; Liver; Male; Middle Aged; NAD; Necrosis; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1967
[What is the current status of therapeutic possibilities in severe juandice?].
    La Presse medicale, 1968, Mar-23, Volume: 76, Issue:14

    Topics: Adolescent; Adult; Child; Coenzyme A; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Hyperbaric Oxygenation; Jaundice; Kidneys, Artificial; Liver; Liver Diseases; Middle Aged; NAD; Perfusion; Peritoneal Dialysis; Prednisolone; Thiamine Pyrophosphate; Thioctic Acid

1968
[Clinical trial of a new coenzyme complex in patients with liver disease].
    La Clinica terapeutica, 1970, Feb-15, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Coenzyme A; Female; Gallbladder Diseases; Humans; Liver Diseases; Male; Middle Aged; NAD; Thiamine Pyrophosphate; Thioctic Acid

1970
Purification and properties of the alpha-ketoglutarate dehydrogenase complex of cauliflower mitochondria.
    The Journal of biological chemistry, 1970, Nov-10, Volume: 245, Issue:21

    Topics: Acyltransferases; Animals; Calcium; Chemical Phenomena; Chemistry; Coenzyme A; Dihydrolipoamide Dehydrogenase; Edetic Acid; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Magnesium; Mitochondria; Myocardium; NAD; Oxidoreductases; Plants; Protein Binding; Succinates; Swine; Thiamine Pyrophosphate; Thioctic Acid

1970
[Importance of biological membranes in metabolism and effects of some functionally bound vitamins].
    Ukrains'kyi biokhimichnyi zhurnal, 1970, Volume: 42, Issue:3

    Topics: Animals; Cell Membrane Permeability; Coenzyme A; Coenzymes; Flavin-Adenine Dinucleotide; Mitochondria, Liver; NAD; Oxidoreductases; Rats; Thiamine Pyrophosphate; Thioctic Acid; Vitamins

1970
[Current views on the therapy of hepatic coma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Apr-15, Volume: 25, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Amino Acids; Ammonia; Anti-Bacterial Agents; Arginine; Aspartic Acid; Coenzyme A; Diet Therapy; Exchange Transfusion, Whole Blood; Glutamates; Hepatic Encephalopathy; Humans; Malates; Male; NAD; Ornithine; Prednisone; Prognosis; Renal Dialysis; Thiamine Pyrophosphate; Thioctic Acid; Vasopressins

1970
Classical maple syrup urine disease: cofactor resistance.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:10

    Topics: Amino Acids; Carbon Isotopes; Cells, Cultured; Coenzyme A; Coenzymes; Female; Fibroblasts; Flavin-Adenine Dinucleotide; Genetics, Medical; Humans; Infant, Newborn; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; NAD; Pyridoxal Phosphate; Pyruvates; Skin; Thiamine Pyrophosphate; Thioctic Acid; Valine

1972
Studies on Escherichia coli pyruvate dehydrogenase complex. I. Effect of bromopyruvate on the catalytic activities of the complex.
    The Journal of biological chemistry, 1972, May-10, Volume: 247, Issue:9

    Topics: Acyltransferases; Binding Sites; Bromine; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gel; Escherichia coli; Kinetics; Oxidoreductases; Protein Binding; Pyruvate Oxidase; Pyruvates; Spectrophotometry; Thiamine Pyrophosphate; Thioctic Acid

1972
[Treatment of hepatic coma in the course of viral hepatitis].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1973, Jul-01, Volume: 26, Issue:13

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Blood Transfusion; Hepatic Encephalopathy; Hepatitis A; Humans; Male; Strophanthins; Thiamine Pyrophosphate; Thioctic Acid

1973
Inhibition of gluconeogenesis and alpha-keto oxidation by 5-methoxyindole-2-carboxylic acid.
    Biochemistry, 1968, Volume: 7, Issue:4

    Topics: Animals; Caprylates; Carbon Dioxide; Carbon Isotopes; Fumarates; Gluconeogenesis; Glutarates; Hydroxybutyrates; Indoles; Keto Acids; Male; Mice; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Succinates; Sulfhydryl Compounds; Thiamine; Thiamine Pyrophosphate; Thioctic Acid

1968
[Metabolic changes in liver diseases and experimental liver damage caused by carbon tetrachloride].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1967, Volume: 48, Issue:11

    Topics: Animals; Carbon Tetrachloride Poisoning; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Citrates; Guinea Pigs; Hepatitis; Humans; Ketoglutaric Acids; Lactates; Liver Cirrhosis; Liver Cirrhosis, Experimental; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1967
Evidence for tighter binding of magnesium-thiamine pyrophosphate to -ketoglutarate dehydrogenase when activated by adenosine monophosphate.
    The Journal of biological chemistry, 1971, Jun-25, Volume: 246, Issue:12

    Topics: Acyltransferases; Adenine Nucleotides; Animals; Binding Sites; Calcium Chloride; Chlorides; Dihydrolipoamide Dehydrogenase; Enzyme Activation; Half-Life; Ketoglutaric Acids; Kinetics; Magnesium; Myocardium; Oxidoreductases; Plants; Protein Binding; Strontium; Succinates; Swine; Thiamine Pyrophosphate; Thioctic Acid

1971
[Acute atrophy of the liver due to viral hepatitis treated by coenzyme A, alpha-lipoic acid, D.P.N and cocarboxylase].
    Revue medico-chirurgicale des maladies du foie, 1966, Volume: 41, Issue:1

    Topics: Adult; Coenzyme A; Hepatitis A; Humans; Male; Thiamine Pyrophosphate; Thioctic Acid

1966
Regulation of the 2-oxoglutarate dehydrogenase lipoate succinyltransferase complex from cauliflower by nucleotide. Pre-steady state kinetics and physical studies.
    The Journal of biological chemistry, 1980, Jun-25, Volume: 255, Issue:12

    Topics: Acyltransferases; Binding Sites; Hydrogen-Ion Concentration; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Mathematics; Multienzyme Complexes; Plants; Protein Binding; Spectrometry, Fluorescence; Succinates; Thiamine Pyrophosphate; Thioctic Acid

1980
[Effect of lipoic acid, cocarboxylase and prednisolone on hepatocyte ultrastructure in toxic hepatitis].
    Arkhiv patologii, 1982, Volume: 44, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Liver; Male; Mushroom Poisoning; Prednisolone; Rats; Thiamine Pyrophosphate; Thioctic Acid

1982
Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
    Archives of biochemistry and biophysics, 2001, Feb-15, Volume: 386, Issue:2

    Topics: Acetylation; Acetyltransferases; Animals; Cattle; Circular Dichroism; Dihydrolipoamide Dehydrogenase; Dihydrolipoyllysine-Residue Acetyltransferase; Humans; Kinetics; Models, Molecular; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Thermodynamics; Thiamine Pyrophosphate; Thioctic Acid

2001
[Effects of combined cocarboxylase & alpha-lipoic acid on postoperative hyperpyruvicemia].
    Il Progresso medico, 1957, Dec-15, Volume: 13, Issue:23

    Topics: Humans; Postoperative Period; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid; Vitamin A; Vitamin K; Vitamins

1957
[Thioctic acid and hepatic function. II. Influence of thioctic acid-cocarboxylase association on amino-acidemic curve by endovenous administration of glycocoll in normal subjects and in liver patients].
    Archivio "E. Maragliano" di patologia e clinica, 1958, Volume: 14, Issue:6

    Topics: Glycine; Glycine Agents; Humans; Liver Diseases; Thiamine Pyrophosphate; Thioctic Acid; Vitamin A; Vitamin K; Vitamins

1958
[Experimental studies on the tissue respiration, particularly on the TCA-cycle of isolated liver and diaphragm. 3. Studies on the O2 consumption of liver homogenate and diaphragm, taken from the thiamine deficient rats, response of Qo2 to panthotenic acid
    Naika hokan. Japanese archives of internal medicine, 1961, Volume: 8

    Topics: Animals; Citric Acid Cycle; Diaphragm; Liver; Metabolism; Muscles; Pantothenic Acid; Phosphates; Rats; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Thioctic Acid; Vitamin B Deficiency

1961
[Efficacy of a mixture of cocarboxylase, DPN, coenzyme A and lipoic acid on hyperpyruvicemia].
    Minerva chirurgica, 1961, Apr-30, Volume: 16

    Topics: Coenzyme A; Coenzymes; Humans; NAD; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid

1961
Inhibitory effect of thiopentone on the pyruvic dehydrogenase in brain. Reversibility of action by thiamine pyrophosphate and lipoic acid.
    Canadian journal of biochemistry and physiology, 1962, Volume: 40

    Topics: Brain; Humans; Neurochemistry; Oxidoreductases; Pyruvates; Thiamine Pyrophosphate; Thioctic Acid; Thiopental

1962
[Metabolic significance of alpha-lipoic acid. V. Comparative action of alpha-lipoic acid, vitamin B 12 and cocarboxylase on metabolism of copper and iron and on aminoacidurias. (Further observations)].
    Arquivo de patologia, 1963, Volume: 35

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Copper; Corrinoids; Hematinics; Humans; Iron; Proteins; Thiamine Pyrophosphate; Thioctic Acid; Vitamin B 12

1963
THE EFFECT OF METABOLIC ACTIVATORS ON THE EXPERIMENTAL CEREBROVASCULAR DISEASE.
    Japanese circulation journal, 1963, Volume: 27

    Topics: Adenosine Triphosphate; Animals; Cerebral Hemorrhage; Cerebrovascular Circulation; Cerebrovascular Disorders; Cytochromes; Dogs; Folic Acid; Histology; Intracranial Embolism; Intracranial Embolism and Thrombosis; Metabolism; Niacin; Nicotinic Acids; Research; Thiamine Pyrophosphate; Thioctic Acid; Vitamin B Complex

1963
[A NEW TREATMENT OF ASCITOGENIC CIRRHOSIS. (PRELIMINARY REPORT)].
    El Dia medico, 1963, Nov-18, Volume: 35

    Topics: Ascites; Humans; Liver Cirrhosis; Thiamine Pyrophosphate; Thioctic Acid

1963