thiamine pyrophosphate and thiazoles

thiamine pyrophosphate has been researched along with thiazoles in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199038 (65.52)18.7374
1990's3 (5.17)18.2507
2000's8 (13.79)29.6817
2010's9 (15.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alspach, JD; Ingraham, LL1
Iwami, K; Mitsuda, H; Takii, Y; Yasumoto, K1
Butler, JR; Davis, PF; Pettit, RH; Reed, LJ1
Angelides, KJ; Hammes, GG1
Gubler, CJ; Murdock, DS1
Iwashima, A; Nose, Y1
Gallo, AA; Sable, HZ2
Keudell, KC; Robertson, NL1
Kravchuk, RI; Mikhal'tsevich, GN; Nikitin, VS; Petushok, VG; Trebukhina, RV1
Oparin, DA; Ostrovskiĭ, IuM; Velichko, MG; Zimatkin, SM; Zimatkina, TI1
Hammes, GG; Lerner, DA; Moe, OA1
Blum, KU; Merkel, R1
Komai, T; Shindo, H1
Brugnoni, GP; Hopmann, RF1
Abe, M; Hayashi, R; Nishimune, T1
Ozawa, T; Saitou, S; Tomita, I1
Hammes, GG; Moe, OA1
Schlee, D1
Briand, C; Chauvet-Monges, AM; Crevat, A; Rogeret, C1
Krampitz, LO1
Hayashi, R; Nishimune, T1
Pappas, PW; Read, CP1
Gubler, CJ; Wittorf, JH1
Bai, P; Bennion, M; Gubler, CJ1
Biaglow, JE; Mieyal, JJ; Sable, HZ; Suchy, J1
Newell, PC; Tucker, RG1
Crosby, J; Lienhard, GE; Stone, R1
Bönicke, R; Kündig, H; Somogyi, JC1
Pletcher, J; Power, L; Sax, M1
Heinroth, I; Hübner, G; Schellenberger, A1
Hübner, G; Kolbe, A; Schellenberger, A1
Hübner, G; Müller, V; Schellenberger, A; Winter, K1
Galitskiĭ, EA; Senkevich, SB; Strumilo, SA; Vinogradov, VV1
Senkevich, SB; Strumilo, SA; Vinogradov, VV1
Murata, K1
Kawasaki, T; Sanemori, H; Ueki, H1
Chun, K; Robinson, BH1
David, S; Estramareix, B1
Golbik, R; Hübner, G; Jordan, F; Seliger, B; Spinka, M; Tittmann, K; Wang, J1
Begley, TP; Ge, Y; Kinsland, C; McLafferty, FW; Xi, J1
BHAGAT, B; LOCKETT, MF1
Begley, TP; Chatterjee, A; Ealick, SE; Jurgenson, CT; Schroeder, FC2
Galhardo, RS; Godoi, PH; Luche, DD; Menck, CF; Oliva, G; Van Sluys, MA1
Cremades, N; Croxen, MA; Harman, WD; Hoffman, PS; Morash, MG; Sisson, G; Welch, K1
SILVERMAN, M1
Forbes, J; Griffith, R; Horne, S; Krautwald, M; Leech, D; Münch, G; Rahmadi, A; Steele, ML1
Abeydeera, ND; Bale, S; Begley, TP; Chatterjee, A; Dorrestein, PC; Ealick, SE; Pai, PJ; Russell, DH1
Hu, NH; Li, SQ1
Fitzpatrick, TB; Moulin, M; Nguyen, GT; Scaife, MA; Smith, AG1
Bassaganya-Riera, J; Bruce, AM; Burgess, SL; Guerrant, RL; Hoffman, PS; Hontecillas, R; Macdonald, TL; Olekhnovich, I; Viladomiu, M; Warren, CA1
Gong, G; Han, S; Hu, Y; Pan, J; Song, Z; Xie, L; Zhang, W1
Chang, CF; Chang, CY; Hsu, LJ; Hsu, NS; Li, TL; Lin, KH; Liu, YC; Lyu, SY; Wang, YL; Wu, CJ1
Bao, W; Chen, Z; Fei, G; Guan, Y; Jiao, F; Jin, L; Liu, H; Pan, S; Pan, X; Ren, S; Sang, S; Shi, H; Wang, C; Wang, Y; Yu, X; Zeng, F; Zhang, Y; Zhong, C; Zhou, W1
Begley, TP; Dorrestein, PC; McLafferty, FW; Zhai, H1
Begley, TP; Chatterjee, A; Dorrestein, PC; McLafferty, FW; Zhai, H1
Bettendorff, L; El Moualij, B; Gangolf, M; Thiry, M; Wins, P1

Reviews

5 review(s) available for thiamine pyrophosphate and thiazoles

ArticleYear
[Recent studies on thiamine, with special reference to its metabolism (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1976, Volume: 21, Issue:5

    Topics: Adenosine Triphosphate; Animals; Humans; Metabolism, Inborn Errors; Nervous System Diseases; Pyrimidines; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Thiazoles

1976
[Thiamine: biosynthesis and its regulation].
    Die Pharmazie, 1972, Volume: 27, Issue:5

    Topics: Adenine Nucleotides; Alanine; Antimetabolites; Bacillus subtilis; Carboxy-Lyases; Coenzymes; Escherichia coli; Glyoxylates; Methionine; Mutation; Purines; Pyrimidines; Saccharomyces cerevisiae; Salmonella typhimurium; Thiamine; Thiamine Pyrophosphate; Thiazoles

1972
Catalytic functions of thiamin diphosphate.
    Annual review of biochemistry, 1969, Volume: 38

    Topics: Aldehyde-Lyases; Animals; Bacteria; Butanones; Carbohydrates; Carbon Isotopes; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Deuterium; Glyoxylates; Pyruvate Oxidase; Pyruvates; Tartronates; Thiamine Pyrophosphate; Thiazoles; Transferases

1969
Actions of two types of thiaminase on thiamin and its analogues.
    Annals of the New York Academy of Sciences, 1982, Volume: 378

    Topics: Alkyl and Aryl Transferases; Animals; Bacillus; Diet; Disulfides; Fishes; Humans; Hydrolases; Oxythiamine; Plants; Pyrimidines; Structure-Activity Relationship; Substrate Specificity; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Thiazoles; Transferases

1982
Sugars and nucleotides and the biosynthesis of thiamine.
    Advances in carbohydrate chemistry and biochemistry, 1997, Volume: 52

    Topics: Carbohydrate Metabolism; Enterobacteriaceae; Fungi; Molecular Structure; Nucleotides; Pentoses; Plants; Pyridoxine; Pyrimidines; Thiamine; Thiamine Pyrophosphate; Thiazoles

1997

Other Studies

53 other study(ies) available for thiamine pyrophosphate and thiazoles

ArticleYear
Inhibition of acetylcholinesterase by thiamine. A structure-function study.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:1

    Topics: Animals; Cholinesterase Inhibitors; Eels; Kinetics; Structure-Activity Relationship; Thiamine

1977
Enzymic formation of thiamine pyrophosphate in plants.
    Journal of nutritional science and vitaminology, 1975, Volume: 21, Issue:1

    Topics: Acid Phosphatase; Adenosine Triphosphate; Enzymes; Magnesium; Organophosphorus Compounds; Phosphoric Acids; Phosphotransferases; Plants; Pyrimidines; Species Specificity; Thiamine; Thiamine Pyrophosphate; Thiazoles; Transferases

1975
Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects of kinase and phosphatase activities.
    Biochemical and biophysical research communications, 1977, Feb-21, Volume: 74, Issue:4

    Topics: Animals; Cattle; Kidney; Kinetics; Phosphoric Monoester Hydrolases; Phosphotransferases; Protein Binding; Pyruvate Dehydrogenase Complex; Thiamine Pyrophosphate; Thiazoles

1977
Mechanism of action of the pyruvate dehydrogenase multienzyme complex from Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:10

    Topics: Escherichia coli; Ethylmaleimide; Flavin-Adenine Dinucleotide; Pyruvate Dehydrogenase Complex; Thiamine Pyrophosphate; Thiazoles

1978
Differential determination of thiamine and its phosphates and hydroxyethiamine and pyrithiamine.
    Methods in enzymology, 1979, Volume: 62

    Topics: Animals; Indicators and Reagents; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Spectrometry, Fluorescence; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Thiamine Triphosphate; Thiazoles

1979
Conformation of complexes of thiamin pyrophosphate with divalent cations as studied by nuclear magnetic resonance spectroscopy.
    The Journal of biological chemistry, 1975, Jul-10, Volume: 250, Issue:13

    Topics: Ligands; Magnetic Resonance Spectroscopy; Manganese; Nickel; Organophosphorus Compounds; Oxythiamine; Temperature; Thiamine; Thiamine Pyrophosphate; Thiazoles

1975
Thiamine requirement of Eikenella corrodens.
    Microbios, 1990, Volume: 63, Issue:255

    Topics: Culture Media; Eikenella corrodens; Pyrimidines; Sterilization; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Thiazoles

1990
[Effect of thiamine and its antimetabolite oxythiamine on the proliferative activity of carcinosarcoma Walker 256 cells].
    Eksperimental'naia onkologiia, 1987, Volume: 9, Issue:2

    Topics: Animals; Carcinoma 256, Walker; Cell Division; Female; Oxythiamine; Rats; Thiamine; Thiamine Pyrophosphate; Thiazoles; Transketolase

1987
[Comparative evaluation of the action of oxythiamine and its derivatives on animals with Erhlich's ascitic cancer].
    Eksperimental'naia onkologiia, 1986, Volume: 8, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Decanoic Acids; Dicarboxylic Acids; Drug Evaluation, Preclinical; Esters; Female; Glutarates; Histocytochemistry; Liver; Mice; Neoplasm Transplantation; Oxythiamine; Thiamine Pyrophosphate; Thiazoles; Time Factors; Transketolase

1986
Fluorescence energy transfer between the thiamine diphosphate and flavine adenine dinucleotide binding sites on the pyruvate dehydrogenase multienzyme complex.
    Biochemistry, 1974, Jun-04, Volume: 13, Issue:12

    Topics: Binding Sites; Catalysis; Energy Transfer; Escherichia coli; Flavin-Adenine Dinucleotide; Fluorescence; Ligands; Mathematics; Oxidation-Reduction; Phosphoric Acids; Pyrimidines; Pyruvate Dehydrogenase Complex; Spectrometry, Fluorescence; Structure-Activity Relationship; Thiamine Pyrophosphate; Thiazoles; Time Factors

1974
[Observations on the determination of thiamine in serum by the thiochrome method (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1974, Volume: 12, Issue:10

    Topics: Humans; Methods; Pyrimidines; Spectrometry, Fluorescence; Thiamine; Thiamine Pyrophosphate; Thiazoles

1974
Structural specificities for the active transport system of thiamine in rat small intestine.
    Journal of nutritional science and vitaminology, 1974, Volume: 20, Issue:3

    Topics: Alanine; Animals; Binding Sites; Biological Transport, Active; Electrophoresis, Paper; Fructose; Galactose; Glucose; Hydrogen-Ion Concentration; Intestine, Small; Leucine; Male; Models, Chemical; Pyrimidines; Rats; Structure-Activity Relationship; Sulfur; Sulfur Radioisotopes; Thiamine; Thiamine Pyrophosphate; Thiazoles

1974
pK of thiamine C(2)H.
    Nature: New biology, 1973, Dec-05, Volume: 246, Issue:153

    Topics: Chemical Phenomena; Chemistry; Ion Exchange; Kinetics; Onium Compounds; Temperature; Thiamine; Thiamine Pyrophosphate; Thiazoles

1973
Quantitative determination of thiamine and its phosphate esters by Sephadex gel filtration.
    Biochimica et biophysica acta, 1972, Oct-25, Volume: 279, Issue:3

    Topics: Chromatography, Gel; Cyanogen Bromide; Dextrans; Escherichia coli; Methods; Mutation; Organophosphorus Compounds; Oxidation-Reduction; Pyrimidines; Spectrometry, Fluorescence; Thiamine; Thiamine Pyrophosphate; Thiazoles

1972
Coenzyme analogue inhibition in the reconstitution of yeast pyruvate decarboxylase and transketolase.
    Biochemical and biophysical research communications, 1974, Mar-15, Volume: 57, Issue:1

    Topics: Apoproteins; Benzyl Compounds; Binding Sites; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Kinetics; Magnesium; Protein Binding; Pyruvates; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thiamine Pyrophosphate; Thiazoles; Transketolase

1974
A study of the binding of thiamine diphosphate and thiochrome diphosphate to the pyruvate dehydrogenase multienzyme complex.
    Biochemistry, 1974, Jun-04, Volume: 13, Issue:12

    Topics: Binding, Competitive; Carbon Radioisotopes; Dialysis; Energy Transfer; Escherichia coli; Flavin-Adenine Dinucleotide; Kinetics; Ligands; Macromolecular Substances; Mathematics; Organophosphorus Compounds; Oxidation-Reduction; Protein Binding; Pyrimidines; Pyruvate Dehydrogenase Complex; Spectrometry, Fluorescence; Structure-Activity Relationship; Thiamine; Thiamine Pyrophosphate; Thiazoles

1974
NMR study of the lability of the thiazolium proton in thiamin and its polyphosphoric esters.
    Biochimica et biophysica acta, 1973, May-28, Volume: 304, Issue:3

    Topics: Deuterium; Half-Life; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Protons; Structure-Activity Relationship; Thiamine; Thiamine Pyrophosphate; Thiazoles

1973
Coenzyme interactions. 8. Carbon 13 nuclear magnetic resonance studies of thiamine and related compounds. Electronic aspects of thiamine catalysis.
    The Journal of biological chemistry, 1974, Mar-10, Volume: 249, Issue:5

    Topics: Antimetabolites; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Computers; Fourier Analysis; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Osmolar Concentration; Oxidation-Reduction; Pyrimidines; Structure-Activity Relationship; Thiamine; Thiamine Pyrophosphate; Thiazoles

1974
Thiamine-binding protein and thiamine uptake by Escherichia coli.
    Biochimica et biophysica acta, 1971, Sep-21, Volume: 244, Issue:3

    Topics: Bacterial Proteins; Biological Transport; Carbon Isotopes; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Dialysis; Drug Stability; Electrophoresis, Disc; Endopeptidases; Escherichia coli; Genetics, Microbial; Hot Temperature; Kinetics; Mutation; Osmotic Pressure; Pepsin A; Protein Binding; Pyrimidines; Thiamine; Thiamine Pyrophosphate; Thiazoles

1971
Thiamine uptake by Hymenolepis diminuta.
    The Journal of parasitology, 1972, Volume: 58, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Cestoda; Dinitrophenols; Iodoacetates; Male; Monosaccharides; Picolines; Pyrimidines; Rats; Rats, Inbred Strains; Sulfur Isotopes; Thiamine; Thiamine Pyrophosphate; Thiazoles; Time Factors; Vitamins

1972
Coenzyme binding in yeast pyruvate decarboxylase. Kinetic studies with thiamine diphosphate analogues.
    European journal of biochemistry, 1971, Oct-26, Volume: 22, Issue:4

    Topics: Binding Sites; Carboxy-Lyases; Decarboxylation; Kinetics; Pyrimidines; Pyruvates; Saccharomyces; Thiamine; Thiamine Pyrophosphate; Thiazoles

1971
Biochemical factors involved in the anorexia of thiamin deficiency in rats.
    The Journal of nutrition, 1971, Volume: 101, Issue:6

    Topics: Aldehydes; Animals; Body Weight; Carbon Dioxide; Carbon Isotopes; Feeding and Eating Disorders; Heptoses; Humans; Intestinal Mucosa; Intestine, Small; Male; Oxidoreductases; Picolines; Pyruvates; Radiochemistry; Rats; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Thiazoles; Time Factors; Transferases

1971
Coenzyme interactions. 3. Characteristics of the molecular complexes of thiamine with indole derivatives.
    The Journal of biological chemistry, 1969, Aug-10, Volume: 244, Issue:15

    Topics: 5-Hydroxytryptophan; Chemical Phenomena; Chemistry; Coenzymes; Deuterium; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Pyrimidines; Spectrophotometry; Thiamine; Thiamine Pyrophosphate; Thiazoles; Tryptamines; Tryptophan; Ultraviolet Rays

1969
The control mechanism of thiamine biosynthesis a model for the study of control of converging pathways.
    The Biochemical journal, 1966, Volume: 100, Issue:2

    Topics: Biological Assay; Enzyme Repression; Ligases; Models, Theoretical; Pyrimidines; Salmonella typhimurium; Thiamine; Thiamine Pyrophosphate; Thiazoles

1966
Mechanisms of thiamine-catalyzed reactions. Decarboxylation of 2-(1-carboxy-1-hydroxyethyl)-3,4-dimethylthiazolium chloride.
    Journal of the American Chemical Society, 1970, May-06, Volume: 92, Issue:9

    Topics: Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Chlorides; Kinetics; Models, Chemical; Pyruvates; Spectrophotometry; Thiamine Pyrophosphate; Thiazoles

1970
[Further experiments on elucidation of the reaction mechanism of thiamine activation by hemin].
    Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1970, Volume: 40, Issue:2

    Topics: Chemical Phenomena; Chemistry; Heme; Thiamine Pyrophosphate; Thiazoles

1970
The crystal structure of N-benzyl-4-methylthiazolium bromide.
    Acta crystallographica. Section B: Structural crystallography and crystal chemistry, 1970, Feb-15, Volume: 26, Issue:2

    Topics: Bromides; Crystallography; Thiamine; Thiamine Pyrophosphate; Thiazoles; X-Ray Diffraction

1970
[On the theory of thiamine pyrophosphate action. VI. Importance of the conformation situation between pyrimidine- and thiazole ring for the coenzyme effect of thiamine pyrophosphate in yeast pyruvate decarboxylase].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1967, Volume: 348, Issue:5

    Topics: Carboxy-Lyases; Chemical Phenomena; Chemistry; Pyrimidines; Pyruvates; Thiamine Pyrophosphate; Thiazoles; Yeasts

1967
[On the theory of cocarboxylase action. I. Influence of pH, N-position residue and metal ions on CH-acidity of thiazolium salts].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1965, Volume: 341, Issue:1

    Topics: Buffers; Chemical Phenomena; Chemistry; Copper; Deuterium; Hydrogen-Ion Concentration; Magnesium; Manganese; Spectrum Analysis; Thiamine Pyrophosphate; Thiazoles; Zinc

1965
[On the theory of cocarboxylase action. II. Origin and fundamentals of a two-center mechanism of thiamine pyrophosphate action from research on models and enzymatic measuremets].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1966, Volume: 344, Issue:4

    Topics: Carbon Isotopes; Carboxy-Lyases; Ketones; Thiamine Pyrophosphate; Thiazoles

1966
[Enzyme activity of thiamine pyrophosphate in the rat after oxythiamine administration].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:11

    Topics: 11-Hydroxycorticosteroids; Adrenal Glands; Animals; Cytosol; Male; Mitochondria; NADP; Oxidation-Reduction; Oxidoreductases; Oxythiamine; Rats; Substrate Specificity; Thiamine Pyrophosphate; Thiazoles

1983
Effect of oxythiamine on adrenal thiamine pyrophosphate-dependent enzyme activities.
    Biomedica biochimica acta, 1984, Volume: 43, Issue:2

    Topics: Adrenal Glands; Animals; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Kinetics; Male; Oxythiamine; Pyruvate Dehydrogenase Complex; Rats; Thiamine Pyrophosphate; Thiazoles; Transketolase

1984
Reversed-phase high-performance liquid chromatographic analysis of thiamine phosphate esters at subpicomole levels.
    Analytical biochemistry, 1980, Sep-15, Volume: 107, Issue:2

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Liver; Microchemistry; Oxidation-Reduction; Pyrimidines; Rats; Thiamine; Thiamine Monophosphate; Thiamine Pyrophosphate; Thiamine Triphosphate; Thiazoles

1980
The relationships between transketolase, yeast pyruvate decarboxylase and pyruvate dehydrogenase of the pyruvate dehydrogenase complex.
    FEBS letters, 1993, Aug-09, Volume: 328, Issue:1-2

    Topics: Amino Acid Sequence; Binding Sites; Humans; Molecular Sequence Data; Pichia; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Saccharomyces cerevisiae; Sequence Alignment; Structure-Activity Relationship; Thiamine Pyrophosphate; Thiazoles; Transketolase

1993
Consequences of a modified putative substrate-activation site on catalysis by yeast pyruvate decarboxylase.
    Biochemistry, 2001, Feb-13, Volume: 40, Issue:6

    Topics: Alanine; Catalysis; Cysteine; Deuterium Oxide; Enzyme Activation; Hydrogen; Kinetics; Models, Chemical; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Serine; Solvents; Substrate Specificity; Thiamine Pyrophosphate; Thiazoles

2001
Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-17, Volume: 98, Issue:15

    Topics: Acylation; Bacterial Proteins; Carrier Proteins; Cross-Linking Reagents; Disulfides; Escherichia coli; Escherichia coli Proteins; Ligases; Molecular Structure; Nucleotidyltransferases; Thiamine Pyrophosphate; Thiazoles; Ubiquitin-Protein Ligases; Ubiquitins

2001
THE EFFECT OF SULPHITE IN SOLID DIETS ON THE GROWTH OF RATS.
    Food and cosmetics toxicology, 1964, Volume: 2

    Topics: Diarrhea; Diet; Feces; Growth; Pharmacology; Pyrimidines; Rats; Research; Sulfites; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Thiazoles; Toxicology

1964
Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis.
    Journal of the American Chemical Society, 2006, Jun-07, Volume: 128, Issue:22

    Topics: Binding Sites; Chromatography, High Pressure Liquid; Eukaryotic Cells; NAD; Protein Conformation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiamine; Thiamine Pyrophosphate; Thiazoles

2006
Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana.
    The Journal of biological chemistry, 2006, Oct-13, Volume: 281, Issue:41

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Escherichia coli; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Thiamine Pyrophosphate; Thiazoles

2006
Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3

    Topics: Acetyl Coenzyme A; Animals; Antiprotozoal Agents; Bacteria, Anaerobic; Campylobacter jejuni; Carbon Dioxide; Cloning, Molecular; Clostridium; Culture Media; Enzyme Inhibitors; Helicobacter pylori; Kinetics; L-Lactate Dehydrogenase; Magnetic Resonance Spectroscopy; Nitro Compounds; Parasites; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Reverse Transcriptase Polymerase Chain Reaction; Thiamine Pyrophosphate; Thiazoles

2007
Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate.
    Journal of the American Chemical Society, 2007, Mar-14, Volume: 129, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; Eukaryotic Cells; NAD; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thiamine; Thiamine Pyrophosphate; Thiazoles

2007
Interactions of atabrine, thiamine, and cocarboxylase.
    The Journal of biological chemistry, 1949, Volume: 178, Issue:1

    Topics: Carboxy-Lyases; Quinacrine; Thiamine; Thiamine Pyrophosphate; Thiazoles

1949
The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase.
    Rejuvenation research, 2011, Volume: 14, Issue:4

    Topics: Animals; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enzyme Assays; Glycation End Products, Advanced; Inhibitory Concentration 50; Kidney; Kinetics; Models, Molecular; Nucleoside-Diphosphate Kinase; Protein Kinase Inhibitors; Thiamine; Thiamine Pyrophosphate; Thiazoles

2011
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
    Nature, 2011, Oct-26, Volume: 478, Issue:7370

    Topics: Amino Acid Sequence; Biocatalysis; Carbon-Nitrogen Lyases; Conserved Sequence; Cysteine; Iron; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfides; Sulfur; Thiamine; Thiamine Pyrophosphate; Thiazoles

2011
Two hydrate pseudopolymorphs of thiamine pyrophosphate: a dihydrate and a trihydrate.
    Acta crystallographica. Section C, Crystal structure communications, 2013, Volume: 69, Issue:Pt 7

    Topics: Crystallization; Hydrogen Bonding; Models, Molecular; Molecular Structure; Pyridinium Compounds; Pyrimidines; Thiamine Pyrophosphate; Thiazoles

2013
Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Sep-03, Volume: 110, Issue:36

    Topics: Algal Proteins; Alternative Splicing; Biosynthetic Pathways; Chlamydomonas reinhardtii; Gene Expression Regulation, Plant; Molecular Structure; Phosphotransferases (Phosphate Group Acceptor); Plant Proteins; Point Mutation; Protein Binding; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Riboswitch; Thiamine; Thiamine Pyrophosphate; Thiazoles

2013
Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Benzamides; Biological Availability; Cell Line; Cell Survival; Dogs; Drug Evaluation, Preclinical; Half-Life; Helicobacter Infections; Helicobacter pylori; Hepatocytes; Humans; Male; Microbial Sensitivity Tests; Microbiota; Microsomes, Liver; Pyruvate Synthase; Rats; Thiamine Pyrophosphate; Thiazoles

2014
Expression, Purification, and Activity of ActhiS, a Thiazole Biosynthesis Enzyme from Acremonium chrysogenum.
    Biochemistry. Biokhimiia, 2017, Volume: 82, Issue:7

    Topics: Acremonium; Adenosine Diphosphate; Amino Acid Sequence; Chromatography, High Pressure Liquid; Fungal Proteins; Glycine; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutagenesis, Site-Directed; NAD; Recombinant Proteins; Sequence Alignment; Thiamine Pyrophosphate; Thiazoles

2017
The Mesomeric Effect of Thiazolium on non-Kekulé Diradicals in Pichia stipitis Transketolase.
    Angewandte Chemie (International ed. in English), 2018, 02-12, Volume: 57, Issue:7

    Topics: Catalytic Domain; Crystallography, X-Ray; Fungal Proteins; Isomerism; Pichia; Recombinant Proteins; Thiamine Pyrophosphate; Thiazoles; Transketolase

2018
Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer's disease, whereas amyloid deposition does not.
    Alzheimer's research & therapy, 2018, 03-01, Volume: 10, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Brain; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Positron-Emission Tomography; Presenilin-1; Psychiatric Status Rating Scales; Thiamine; Thiamine Pyrophosphate; Thiazoles

2018
The biosynthesis of the thiazole phosphate moiety of thiamin: the sulfur transfer mediated by the sulfur carrier protein ThiS.
    Chemistry & biology, 2004, Volume: 11, Issue:10

    Topics: Amino Acid Sequence; Bacillus subtilis; Carrier Proteins; Catalysis; Escherichia coli Proteins; Molecular Sequence Data; Pentosephosphates; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds; Thiamine; Thiamine Triphosphate; Thiazoles; Transferases

2004
Simultaneous kinetic characterization of multiple protein forms by top down mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2005, Volume: 16, Issue:7

    Topics: Bacillus subtilis; Escherichia coli; Isoenzymes; Kinetics; Reproducibility of Results; Ribonuclease, Pancreatic; Ribonucleases; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Thiamine Triphosphate; Thiazoles

2005
Thiamine triphosphate synthesis in rat brain occurs in mitochondria and is coupled to the respiratory chain.
    The Journal of biological chemistry, 2010, Jan-01, Volume: 285, Issue:1

    Topics: Adenosine Triphosphate; Animals; Brain; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dicyclohexylcarbodiimide; Electron Transport; Hydrolysis; Kinetics; Male; Methacrylates; Mitochondria; Oligomycins; Phosphates; Proton-Motive Force; Rats; Rats, Wistar; Staining and Labeling; Subcellular Fractions; Substrate Specificity; Temperature; Thiamine Triphosphate; Thiazoles; Valinomycin

2010