thiamine pyrophosphate has been researched along with glutamic acid in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Lindqvist, Y; Meshalkina, L; Nikkola, M; Nilsson, U; Schneider, G; Sundström, M; Wikner, C | 1 |
| Candy, JM; Duggleby, RG; Koga, J; Nixon, PF | 1 |
| Hübner, G; Kern, D; Kern, G; Killenberg-Jabs, M; Neef, H; Schneider, G; Tittmann, K; Wikner, C | 1 |
| Duggleby, RG; Fang, R; Nixon, PF | 1 |
| Chang, AK; Duggleby, RG; Nixon, PF | 1 |
| Furey, W; Guo, F; Hübner, G; Jordan, F; Liu, M; Sergienko, EA; Tittmann, K; Wang, J | 1 |
| Jordan, F | 1 |
| Arjunan, P; Furey, W; Hübner, G; Jordan, F; Joseph, E; Nemeria, N; Tittmann, K; Vazquez-Coll, MB; Zhou, L | 1 |
| Batifoulier, F; Besson, C; Chanliaud, E; Demigné, C; Rémésy, C; Verny, MA | 1 |
| Chipman, DM; Shaanan, B | 1 |
| Friedemann, R; Jordan, F; Meyer, D; Nemeria, N; Neumann, P; Parthier, C; Tittmann, K | 1 |
| Balakrishnan, A; Barak, Z; Binshtein, E; Chipman, D; Jordan, F; Nemeria, N; Patel, H; Shaanan, B; Vered, I | 1 |
| Baig, IA; Kim, MS; Koo, BS; Moon, JY; Yoon, MY | 1 |
| Arena de Souza, V; Bumann, M; Lobley, CM; Lukacik, P; O'Toole, PW; Owens, RJ; Walsh, MA | 1 |
| Bettendorff, L; Bunik, V; Graf, A; Mkrtchyan, G | 1 |
| Mata, RA; Paulikat, M; Tittmann, K; Wechsler, C | 1 |
| Aldeghi, M; Begley, T; de Groot, BL; Rabe von Pappenheim, F; Shome, B; Tittmann, K | 1 |
1 review(s) available for thiamine pyrophosphate and glutamic acid
| Article | Year |
|---|---|
Reaction mechanisms of thiamin diphosphate enzymes: new insights into the role of a conserved glutamate residue.
Topics: Crystallography, X-Ray; Glutamic Acid; Kinetics; Protein Conformation; Substrate Specificity; Thiamine Pyrophosphate | 2009 |
16 other study(ies) available for thiamine pyrophosphate and glutamic acid
| Article | Year |
|---|---|
Analysis of an invariant cofactor-protein interaction in thiamin diphosphate-dependent enzymes by site-directed mutagenesis. Glutamic acid 418 in transketolase is essential for catalysis.
Topics: Animals; Catalysis; Cell Line; Circular Dichroism; Crystallography, X-Ray; Glutamic Acid; Mutagenesis, Site-Directed; Rabbits; Recombinant Proteins; Thiamine Pyrophosphate; Transketolase | 1994 |
The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylase.
Topics: Amino Acid Sequence; Binding Sites; Escherichia coli; Glutamic Acid; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Pyruvate Decarboxylase; Recombinant Proteins; Sequence Homology, Amino Acid; Thiamine Pyrophosphate; Zymomonas | 1996 |
How thiamine diphosphate is activated in enzymes.
Topics: Allosteric Regulation; Binding Sites; Catalysis; Deuterium; Enzyme Activation; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Protons; Pyruvate Decarboxylase; Pyruvates; Thermodynamics; Thiamine Pyrophosphate; Transketolase | 1997 |
Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase.
Topics: Amino Acid Sequence; Catalytic Domain; Glutamic Acid; Humans; Kinetics; Molecular Sequence Data; Protein Binding; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Recombinant Proteins; Sequence Alignment; Thiamine Pyrophosphate | 1998 |
Aspartate-27 and glutamate-473 are involved in catalysis by Zymomonas mobilis pyruvate decarboxylase.
Topics: Aspartic Acid; Catalysis; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Pyruvate Decarboxylase; Substrate Specificity; Thiamine Pyrophosphate; Zymomonas | 1999 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Carbon Dioxide; Catalysis; Catalytic Domain; Cloning, Molecular; DNA, Recombinant; Enzyme Activation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thiamine Pyrophosphate | 2001 |
Biochemistry. How active sites communicate in thiamine enzymes.
Topics: Amino Acid Substitution; Binding Sites; Dihydrolipoyllysine-Residue Acetyltransferase; Dimerization; Geobacillus stearothermophilus; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Protons; Pyruvate Dehydrogenase (Lipoamide); Pyruvate Dehydrogenase Complex; Thiamine Pyrophosphate | 2004 |
Glutamate 636 of the Escherichia coli pyruvate dehydrogenase-E1 participates in active center communication and behaves as an engineered acetolactate synthase with unusual stereoselectivity.
Topics: Acetolactate Synthase; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Dose-Response Relationship, Drug; Escherichia coli; Genetic Variation; Glutamic Acid; Kinetics; Lactates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Pyrimidine Nucleosides; Pyruvate Dehydrogenase (Lipoamide); Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Temperature; Thiamine Pyrophosphate; Trypsin; Ultraviolet Rays | 2005 |
Restoration of thiamine status with white or whole wheat bread in a thiamine-depleted rat model.
Topics: Animals; Body Weight; Bread; Cerebellum; Diet; Disease Models, Animal; Glucose; Glutamic Acid; Kidney; Lactic Acid; Liver; Pyruvic Acid; Rats; Rats, Wistar; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Triticum | 2007 |
Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate .
Topics: Amines; Binding Sites; Catalysis; Crystallography, X-Ray; Decarboxylation; Glutamic Acid; Thermodynamics; Thiamine Pyrophosphate; X-Rays; Zymomonas | 2010 |
Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.
Topics: Amino Acid Substitution; Circular Dichroism; Gene Expression Regulation; Glutamic Acid; Hydrogen-Ion Concentration; Ligases; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Pyrimidines; Pyruvic Acid; Substrate Specificity; Thiamine Pyrophosphate | 2012 |
Structural and functional significance of the highly-conserved residues in Mycobacterium tuberculosis acetohydroxyacid synthase.
Topics: Acetolactate Synthase; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalysis; Conserved Sequence; Dimerization; Escherichia coli; Glutamic Acid; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thiamine Pyrophosphate | 2014 |
High-resolution structures of Lactobacillus salivarius transketolase in the presence and absence of thiamine pyrophosphate.
Topics: Apoproteins; Catalytic Domain; Coenzymes; Crystallization; Crystallography, X-Ray; Glutamic Acid; Lactobacillus; Models, Molecular; Phylogeny; Protein Structure, Secondary; Solutions; Structural Homology, Protein; Thiamine Pyrophosphate; Transketolase | 2015 |
Cellular thiamine status is coupled to function of mitochondrial 2-oxoglutarate dehydrogenase.
Topics: Animals; Cerebral Cortex; Cytoplasm; Glutamic Acid; Homeostasis; Ketoglutarate Dehydrogenase Complex; Mice; Mitochondria; Organophosphonates; Succinates; Thiamine; Thiamine Pyrophosphate | 2016 |
Theoretical Studies of the Electronic Absorption Spectra of Thiamin Diphosphate in Pyruvate Decarboxylase.
Topics: Bacterial Proteins; Catalytic Domain; Coenzymes; Electron Transport; Gene Expression; Glutamic Acid; Kinetics; Molecular Dynamics Simulation; Mutation; Protein Structure, Secondary; Pyrimidines; Pyruvate Decarboxylase; Static Electricity; Thermodynamics; Thiamine Pyrophosphate; Zymomonas | 2017 |
Structural basis for antibiotic action of the B
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Catalytic Domain; Coenzymes; Drug Design; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Humans; Hydrogen Bonding; Kinetics; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Thiamine; Thiamine Pyrophosphate; Transketolase | 2020 |