Compounds > theophylline

theophylline and zonisamide

theophylline has been researched along with zonisamide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Thöne, J; Wiemann, M1
Leniger, T; Splettstösser, F; Thöne, J; Wiemann, M1
Cumming, KI; Kaialy, W; Nokhodchi, A; Shojaee, S1
Alhalaweh, A; Cumming, I; Kaialy, W; Nokhodchi, A; Shojaee, S1
Maniruzzaman, M; Nokhodchi, A; Shojaee, S1

Reviews

1 review(s) available for theophylline and zonisamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for theophylline and zonisamide

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons.
    Epilepsy research, 2007, Volume: 76, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoxazoles; Neural Inhibition; Neurons; Serotonin; Theophylline; Zonisamide

2007
Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.
    Epilepsy research, 2008, Volume: 79, Issue:2-3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Electrophysiology; Epilepsy; Female; Guinea Pigs; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Isoxazoles; Membrane Potentials; Microelectrodes; Neurons; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Theophylline; Zonisamide

2008
Comparative evaluation of drug release from aged prolonged polyethylene oxide tablet matrices: effect of excipient and drug type.
    Pharmaceutical development and technology, 2016, Volume: 21, Issue:2

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Excipients; Hydrophobic and Hydrophilic Interactions; Isoxazoles; Lactose; Molecular Weight; Oxides; Polyethylene Glycols; Propranolol; Solubility; Tablets; Theophylline; Water; Zonisamide

2016
Investigation of Drug Release from PEO Tablet Matrices in the Presence of Vitamin E as Antioxidant.
    Current drug delivery, 2015, Volume: 12, Issue:5

    Topics: Antioxidants; Drug Liberation; Humans; Isoxazoles; Molecular Structure; Molecular Weight; Polyethylene Glycols; Propranolol; Solubility; Tablets; Theophylline; Vitamin E; Zonisamide

2015
Evaluation of the drug solubility and rush ageing on drug release performance of various model drugs from the modified release polyethylene oxide matrix tablets.
    Drug delivery and translational research, 2017, Volume: 7, Issue:1

    Topics: Delayed-Action Preparations; Drug Liberation; Drug Stability; Hardness; Isoxazoles; Polyethylene Glycols; Propranolol; Solubility; Tablets; Theophylline; Zonisamide

2017