theophylline has been researched along with zaprinast in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 10 (47.62) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bristol, JA; Cain, MH; Weishaar, RE | 1 |
| Arch, JR; Buckle, DR; Connolly, BJ; Fenwick, AE; Foster, KA; Murray, KJ; Readshaw, SA; Smallridge, M; Smith, DG | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Gauthier, C; Le Bec, A; Lugnier, C; Soustre, H | 1 |
| Donaldson, J; Hall, IP; Hill, SJ | 1 |
| Brazdil, R; Diocee, BK; Jordan, R; Souness, JE | 1 |
| Clark, KL; Drew, GM; Hilditch, A | 1 |
| Frossard, N; Landry, Y; Pauli, G; Ruckstuhl, M | 1 |
| Fredholm, B; Sydbom, A; Uvnäs, B | 1 |
| Abman, SH; Clarke, WR; Fox, JJ; Ivy, DD; Kinsella, JP; Ziegler, JW | 1 |
| Adgey, AA; Allen, JD; Herity, NA; Silke, B | 1 |
| Advenier, C; Naline, E; Palette-Pays, C; Varoquaux, O; Zhang, Y | 1 |
| Howell, RE; Sickels, BD; Woeppel, SL | 1 |
| Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Paoletti, G; Piretto, V; Trovati, M | 1 |
| Dahl, SG; Lagente, V; Payne, AN; Planquois, JM; Ruffin-Morin, Y | 2 |
| Chambers, DJ; Featherstone, RL; Kelly, FJ | 1 |
| Bardou, M; Dumas, J; Dumas, M; Goirand, F; Rochette, L | 1 |
| Baba, A; Enomoto, R; Lee, E; Matsuda, T; Mori, K; Takuma, K | 1 |
| Ozdem, SS; Sadan, G; Tasatargil, A | 1 |
| Aronsen, L; Lysaa, R; Orvoll, E; Ravna, AW; Sager, G | 1 |
1 review(s) available for theophylline and zaprinast
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity | 1985 |
20 other study(ies) available for theophylline and zaprinast
| Article | Year |
|---|---|
Inhibition of cyclic nucleotide phosphodiesterase by derivatives of 1,3-bis(cyclopropylmethyl)xanthine.
Topics: Adenosine; Alkylation; Animals; Binding Sites; Brain; Male; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Structure-Activity Relationship; Xanthines | 1994 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cyclic nucleotide phosphodiesterases from frog atrial fibers: isolation and drug sensitivities.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Chloride; Calmodulin; Chromatography, Ion Exchange; Cyclic GMP; Cytosol; Dipyridamole; Heart Atria; Heart Ventricles; Kinetics; Myocardium; Papaverine; Purinones; Pyrrolidinones; Rana esculenta; Rana ridibunda; Rolipram; Substrate Specificity; Theophylline | 1992 |
Modulation of carbachol-induced inositol phosphate formation in bovine tracheal smooth muscle by cyclic AMP phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Albuterol; Animals; Calcium; Carbachol; Cattle; Colforsin; Cyclic AMP; Drug Interactions; In Vitro Techniques; Inositol Phosphates; Male; Membrane Lipids; Muscle, Smooth; Phospholipids; Purinones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1990 |
Role of selective cyclic GMP phosphodiesterase inhibition in the myorelaxant actions of M&B 22,948, MY-5445, vinpocetine and 1-methyl-3-isobutyl-8-(methylamino)xanthine.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Kinetics; Male; Methylene Blue; Muscle Relaxants, Central; Nitric Oxide; Phthalazines; Purinones; Pyridazines; Rats; Rats, Inbred Strains; Theophylline; Vinca Alkaloids | 1989 |
Potentiation of the effects of dopamine in the rabbit isolated splenic artery by 3-isobutyl-1-methylxanthine or forskolin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Benzopyrans; Colforsin; Cromakalim; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Parasympatholytics; Purinergic Antagonists; Purinones; Pyrroles; Rabbits; Splenic Artery; Theophylline | 1989 |
Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aza Compounds; Cromolyn Sodium; Cyclic AMP; Cyclic GMP; Cyclopentanes; Histamine Release; Humans; In Vitro Techniques; Lung; Male; Papaverine; Purinones; Pyrrolidinones; Rats; Rolipram; Theophylline | 1981 |
Evidence against a role of cyclic nucleotides in the regulation of anaphylactic histamine release in isolated rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aza Compounds; Cyclic AMP; Cyclic GMP; Histamine Release; Male; Mast Cells; Purinones; Rats; Rats, Inbred Strains; Theophylline | 1981 |
Dipyridamole, a cGMP phosphodiesterase inhibitor, causes pulmonary vasodilation in the ovine fetus.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arterioles; Dipyridamole; Fetus; Hemodynamics; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Purinones; Receptors, Purinergic P1; Sheep; Theophylline; Time Factors; Vascular Resistance; Vasodilation | 1995 |
Comparison of the ability of nicardipine, theophylline and zaprinast to restore cardiovascular haemodynamics following inhibition of nitric oxide synthesis.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blood Pressure; Calcium; Cardiac Output; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide; Purinones; Swine; Theophylline; Vascular Resistance; Vasodilation | 1994 |
Effect of molsidomine and linsidomine on the human isolated bronchus and the guinea-pig isolated trachea.
Topics: Animals; Bronchi; Bronchodilator Agents; Epithelium; Guinea Pigs; Humans; In Vitro Techniques; Isoproterenol; Male; Methylene Blue; Molsidomine; Muscle, Smooth; Nitroprusside; Purinones; Pyridazines; Theophylline; Trachea | 1993 |
Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs.
Topics: Aminophylline; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine Antagonists; Isoenzymes; Lung; Male; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyrrolidinones; Rolipram; SRS-A; Theophylline | 1993 |
Insulin exerts opposite effects on platelet function at physiological and supraphysiological concentrations.
Topics: Adenosine Diphosphate; Adult; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Insulin; Male; Nitroglycerin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinones; Theophylline; Vasodilator Agents | 1996 |
Salbutamol potentiates the relaxant effects of selective phosphodiesterase inhibitors on guinea pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic beta-Agonists; Albuterol; Animals; Drug Synergism; Guanidines; Guinea Pigs; Histamine; In Vitro Techniques; Male; Milrinone; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth; Osmolar Concentration; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Differential inhibition by selective phosphodiesterase inhibitors of antigen, LTC4 and histamine-induced contraction of guinea-pig isolated trachea.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Animals; Bronchoconstrictor Agents; Bronchodilator Agents; Guanidines; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Leukotriene C4; Male; Milrinone; Muscle Tonus; Ovalbumin; Phosphodiesterase Inhibitors; Purinones; Pyridazines; Pyridones; Pyrrolidinones; Rolipram; Theophylline; Trachea | 1996 |
Comparison of phosphodiesterase inhibitors of differing isoenzyme selectivity added to St. Thomas' hospital cardioplegic solution used for hypothermic preservation of rat lungs.
Topics: Animals; Bicarbonates; Calcium Chloride; Hypothermia, Induced; Lung; Lung Transplantation; Magnesium; Milrinone; Oxygen; Phosphodiesterase Inhibitors; Potassium Chloride; Pulmonary Gas Exchange; Purinones; Rats; Rats, Wistar; Reperfusion Injury; Rolipram; Sodium Chloride; Theophylline; Vascular Resistance | 2000 |
Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Potassium Channels; Purinones; Rats; Rats, Wistar; Rolipram; Theophylline; Vasoconstriction | 2001 |
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model.
Topics: Alkaloids; Animals; Animals, Newborn; Apoptosis; Astrocytes; Carbazoles; Cell Survival; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytochrome c Group; Dipyridamole; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Mitochondria; Pentoxifylline; Peptide Hydrolases; Phosphodiesterase Inhibitors; Purinones; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Theophylline; Vinca Alkaloids | 2001 |
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Electric Stimulation; Guinea Pigs; Histamine; Isoproterenol; Male; Milrinone; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Artery; Purinones; Quinoxalines; Receptors, Adrenergic; Receptors, Cholinergic; Signal Transduction; Tetrodotoxin; Theophylline | 2003 |
Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors.
Topics: ATP-Binding Cassette Transporters; Caffeine; Carbolines; Cyclic AMP; Cyclic GMP; Dipyridamole; Humans; Imidazoles; Kinetics; Multidrug Resistance-Associated Proteins; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purinones; Sulfones; Tadalafil; Theophylline; Triazines; Vardenafil Dihydrochloride | 2014 |