theophylline and xanthine

theophylline has been researched along with xanthine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199023 (57.50)18.7374
1990's7 (17.50)18.2507
2000's5 (12.50)29.6817
2010's4 (10.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Hasegawa, T; Iwasaki, N; Kakiuchi, M; Kato, H; Konno, K; Miyamoto, K; Sakai, R; Sanae, F; Takagi, K; Yamamoto, Y1
Abdallah, AH; Daly, JW; Dickerson, GA; Peet, NP; Ukena, D1
Brufani, M; Cavallaro, RA; Filocamo, L; Galione, A; Galuppi, A; Genazzani, AA1
Cameron, IL; Lyles, MB; Rawls, HR1
Bearne, SL; Lunn, FA; Roy, AC1
Grabb, MC; Roche, FM; Sciotti, VM; Van Wylen, DG1
Higashino, K; Hiroishi, K; Moriwaki, Y; Suda, M; Takahashi, S; Yamamoto, T1
Griot, C; Peterhans, E; Richard, A; Stocker, R; Vandevelde, M1
Brackett, LE; Daly, JW1
Gilboe, DP1
Boorsma, M; Jonkman, JH; Koëter, GH; Kraan, J; van der Mark, TW1
Hafkenscheid, JC; Hekster, YA; Nouws, JF; Vree, JB; Vree, TB1
Bansinath, M; Chopra, KS; Ghosh, SS; Mathur, VS; Shafiqa, A; Shukla, VK1
Carney, JM; Logan, L; McMaster, SB; Seale, TW1
Borea, PA; Danhof, M; IJzerman, AP; Mathôt, RA; van der Wenden, EM; Varani, K; von Frijtag Drabbe Künzel, JK1
Castro, GD; Castro, JA; Costantini, MH; Delgado de Layño, AM1
Alfaro, V; Genescà, M; Hotter, G; Miquel, R; Pi, F; Sola, A; Xaus, C1
BLAKE, M; HARRIS, LE1
LIVESAY, WR; MOYER, JH1
MOYER, JH; SNYDER, HB1
BATTERMAN, RC; BLACKMAN, AL; BROOKS, AM; GROSSMAN, AJ; SCHWIMMER, J1
BICHI, G; SANCIO, L; SERCHI, G1
KATZ, S; MAST, GW1
FERGUSON, JK; MCCOLL, JD; PARKER, JM1
RODARI, T1
SALVINI, L; VIOLA, S1
CASS, LJ; FREDERIK, WS1
FERUGLIO, FS; MIGHELI, B1
SZIRMAI, E1
DUSSAUT, A; FEUNEDECOLOMBI, G; SCIARROTTA, NO1
FUKUDA, H1
AGUSTINARZENO, J; DEFERNANDEZBLANCO, JF; FERNANDEZBLANCO, E1
FIRTH, A; SMITH, WG1
BROUILLET-GABRIEL, MT; DUMON, G; PASQUET, P1
Anstis, M; Edwards, HG; Munshi, T1
Gopishetty, S; Kale, Y; Louie, TM; Subramanian, M; Summers, R; Yu, CL1
Aravind, UK; Aravindakumar, CT; Pramod, G; Saha, A; Sunil Paul, MM1
Laing, T; Lake, BR; Mohamed, HA; Phillips, RM; Willans, CE1
Dong, ZB; Liang, YR; Lu, J; Ma, YX; Wu, HS; Wu, XH; Ye, JH; Zheng, XQ1
Li, X; Liu, X; Ma, C; Wu, T; Xia, T; Zheng, C; Zhou, B1

Trials

2 trial(s) available for theophylline and xanthine

ArticleYear
Effect of theophylline and enprofylline on bronchial hyperresponsiveness.
    Thorax, 1989, Volume: 44, Issue:12

    Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Double-Blind Method; Drug Administration Schedule; Forced Expiratory Volume; Humans; Injections, Intravenous; Male; Methacholine Chloride; Methacholine Compounds; Theophylline; Xanthine; Xanthines

1989
Assessment of bio(in)equivalence of deriphyllin-digoxin in human volunteers.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:1

    Topics: Adult; Biological Availability; Digoxin; Drug Combinations; Female; Humans; Male; Random Allocation; Solubility; Tablets; Theophylline; Therapeutic Equivalency; Xanthine; Xanthines

1986

Other Studies

38 other study(ies) available for theophylline and xanthine

ArticleYear
Effects of alkyl substitutions of xanthine skeleton on bronchodilation.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Airway Resistance; Animals; Bronchodilator Agents; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Organ Specificity; Receptors, Purinergic; Structure-Activity Relationship; Trachea; Xanthines

1992
Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Adenosine; Animals; Bronchi; Guinea Pigs; Humans; Muscle Contraction; Pyrazoles; Rats; Receptors, Purinergic; Structure-Activity Relationship

1988
Potentiation of cADPR-induced Ca(2+)-release by methylxanthine analogues.
    Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14

    Topics: Adenosine Diphosphate Ribose; Animals; Caffeine; Calcium; Cyclic ADP-Ribose; Drug Evaluation, Preclinical; In Vitro Techniques; Ovum; Ryanodine Receptor Calcium Release Channel; Sea Urchins; Structure-Activity Relationship; Xanthines

1999
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange.
    Journal of medicinal chemistry, 2001, Dec-20, Volume: 44, Issue:26

    Topics: Acridine Orange; Intercalating Agents; Methylation; Nonlinear Dynamics; Spectrophotometry; Structure-Activity Relationship; Xanthines

2001
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines

2010
Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:4

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Male; Neurotoxins; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Xanthine; Xanthines

1992
Theophylline-induced increase in plasma uric acid--purine catabolism increased by theophylline.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:7

    Topics: Administration, Oral; Adult; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Male; Nucleotides; Purines; Theophylline; Tumor Cells, Cultured; Uric Acid; Xanthine; Xanthines

1991
Selective degeneration of oligodendrocytes mediated by reactive oxygen species.
    Free radical research communications, 1990, Volume: 11, Issue:4-5

    Topics: Animals; Benzamides; Brain; Cell Survival; Cells, Cultured; Demyelinating Diseases; Dogs; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Oligodendroglia; Oxygen; Superoxides; Theophylline; Xanthine; Xanthine Oxidase; Xanthines

1990
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1

    Topics: Adenosine; Animals; Carbachol; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Purinergic; Theophylline; Thionucleosides; Trachea; Xanthine; Xanthines

1991
The mechanism of caffeine-enhanced glucose stimulation of liver glycogen synthase phosphatase activity.
    Biochemical pharmacology, 1986, Jul-01, Volume: 35, Issue:13

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Drug Interactions; Glucose; Glucose-6-Phosphate; Glucosephosphates; Liver; Male; Phosphoprotein Phosphatases; Rats; Structure-Activity Relationship; Theobromine; Theophylline; Time Factors; Xanthine; Xanthines

1986
Excretion and metabolism of a series of xanthines by the turtle Pseudemys scripta elegans.
    The veterinary quarterly, 1989, Volume: 11, Issue:1

    Topics: Animals; Caffeine; Theobromine; Theophylline; Turtles; Uric Acid; Xanthine; Xanthines

1989
Sensitivity of inbred mice to methylxanthines is not determined by plasma xanthine concentration.
    Neuroscience letters, 1985, May-01, Volume: 56, Issue:1

    Topics: Animals; Body Temperature; Caffeine; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Motor Activity; Species Specificity; Theophylline; Xanthine; Xanthines

1985
Partial agonism of theophylline-7-riboside on adenosine receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:6

    Topics: Animals; Cells, Cultured; Colforsin; Guanosine Triphosphate; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1; Temperature; Theophylline; Xanthine; Xanthines

1994
Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects.
    Teratogenesis, carcinogenesis, and mutagenesis, 2001, Volume: 21, Issue:2

    Topics: Acetaldehyde; Alcohol Drinking; Allopurinol; Animals; Antimetabolites; Caffeine; Carcinogens; Chromatography, Gas; Cytosol; Diet; Enzyme Inhibitors; Ethanol; Free Radicals; Gas Chromatography-Mass Spectrometry; Hypoxanthine; Male; Meat; NAD; Neoplasms; Niacinamide; Phosphodiesterase Inhibitors; Prostate; Prostatic Neoplasms; Purines; Rats; Rats, Sprague-Dawley; Spin Trapping; Temperature; Theobromine; Theophylline; Time Factors; Vasodilator Agents; Xanthine; Xanthine Oxidase

2001
Role of changes in tissular nucleotides on the development of apoptosis during ischemia/reperfusion in rat small bowel.
    The American journal of pathology, 2002, Volume: 161, Issue:5

    Topics: Adenosine; Animals; Apoptosis; Caspase 3; Caspases; Cold Temperature; Intestinal Mucosa; Intestine, Small; Male; Nitric Oxide; Nitrogen Oxides; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Reperfusion Injury; Spermine; Theophylline; Xanthine

2002
The action of solubilizing agents on the solubility of xanthine derivatives in water. II. The application of conductimetric titrations to the study of xanthine combinations.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1952, Volume: 41, Issue:10

    Topics: Caffeine; Diuretics; Solubility; Theobromine; Theophylline; Water; Xanthine; Xanthines

1952
The renal hemodynamic effects of a xanthine compound, diethylaminoethyl theophylline hydrochloride (Parephyllin).
    The Journal of pharmacology and experimental therapeutics, 1953, Volume: 109, Issue:2

    Topics: Electrolytes; Hemodynamics; Kidney; Theophylline; Water; Xanthine; Xanthines

1953
The cerebral hemodynamic response to the xanthine compound, parephyllin (diethyl-aminoethyl theophylline hydrochloride).
    American heart journal, 1954, Volume: 47, Issue:5

    Topics: Brain; Cardiovascular System; Hemodynamics; Humans; Theophylline; Xanthine; Xanthines

1954
Choline theophyllinate, a new xanthine drug for the effective oral treatment of congestive heart failure; a preliminary report.
    International record of medicine and general practice clinics, 1954, Volume: 167, Issue:5

    Topics: Choline; Heart Failure; Humans; Theophylline; Treatment Outcome; Xanthine; Xanthines

1954
[The xanthines. I. Benzyl derivates of 1-3 dimethyl xanthine].
    Il Farmaco; edizione scientifica, 1955, Volume: 10, Issue:10

    Topics: Theophylline; Xanthine; Xanthines

1955
Choline theophyllinate; new xanthine derivative; a review.
    Journal of the American Geriatrics Society, 1956, Volume: 4, Issue:3

    Topics: Choline; Theophylline; Xanthine; Xanthines

1956
A comparison of the relative toxic, emetic and convulsive actions of a series of methylated xanthine derivatives.
    The Journal of pharmacology and experimental therapeutics, 1956, Volume: 116, Issue:3

    Topics: Emetics; Poisoning; Seizures; Theophylline; Vomiting; Xanthine; Xanthines

1956
[Combination of Rauwolfia serpentina with a new xanthine derivative in therapy of arterial hypertension].
    Minerva medica, 1957, Feb-10, Volume: 48, Issue:12

    Topics: Humans; Hypertension; Rauwolfia; Reserpine; Theophylline; Xanthine; Xanthines

1957
[Pharmacological & clinical aspects of a new xanthine derivative; choline theophyllinate].
    Minerva medica, 1957, Apr-04, Volume: 48, Issue:27

    Topics: Choline; Humans; Theophylline; Xanthine; Xanthines

1957
A new xanthine derivative: theophylline with diethylenediamine; a clinical study.
    New York state journal of medicine, 1958, Jul-15, Volume: 58, Issue:14

    Topics: Asthma; Biomedical Research; Piperazines; Theophylline; Xanthine; Xanthines

1958
[Effects of a xanthine derivative (1,3-methyl-omega-piperidine-butyl-xanthine) on cerebral hemodynamics and metabolism].
    Gazzetta medica italiana, 1959, Volume: 118, Issue:1

    Topics: Brain; Hemodynamics; Humans; Piperidines; Theophylline; Xanthine; Xanthines

1959
[Studies on an iodocholine-xanthine preparation in treatment of arteriosclerosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1960, Mar-01, Volume: 15

    Topics: Arteriosclerosis; Choline; Humans; Theophylline; Xanthine; Xanthines

1960
[7-(3-(METHYL-OXYETHYLAMINE)-2-OXYPROPYL)-1,3-DIMETHYL-XANTHINE NICOTINATE IN ADVANCED VASCULAR DISEASES].
    La Semana medica, 1963, Jul-01, Volume: 123

    Topics: Fibrinolysis; Injections, Intramuscular; Leg Ulcer; Niacin; Nicotinic Acids; Tablets; Theophylline; Toxicology; Vascular Diseases; Xanthine; Xanthines

1963
[STUDIES ON THE SYNTHESES OF XANTHINE DERIVATIVES. V. SYNTHESES OF SOME 7-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOPHYLINE AND 1-(2-HYDROXY-3-ALKYLAMINOPROPYL)THEOBROMINE AND THEIR DERIVATIVES].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1963, Volume: 83

    Topics: Chemistry, Pharmaceutical; Coronary Disease; Pharmacology; Pharmacy; Pregnenes; Research; Theobromine; Theophylline; Vasodilator Agents; Xanthine; Xanthines

1963
[7-(3-(METHYL-OXYETHYLAMINE)-2-OXYPROPYL)-1, 3-DIMETHYL-XANTHINE NICOTINATE IN CHRONIC OBLITERATING ANGIOPATHIES].
    La Semana medica, 1963, Nov-28, Volume: 123

    Topics: Arteriosclerosis; Arteriosclerosis Obliterans; Cholesterol; Coronary Disease; Humans; Intracranial Arteriosclerosis; Lipid Metabolism; NAD; Niacin; Nicotinic Acids; Pharmacology; Theophylline; Toxicology; Vascular Diseases; Vasodilator Agents; Vasomotor System; Xanthine

1963
THE ANTI-ANAPHYLACTIC ACTIVITY OF THEOPHYLLINE AND SOME RELATED XANTHINE DERIVATIVES.
    The Journal of pharmacy and pharmacology, 1964, Volume: 16

    Topics: Anaphylaxis; Anti-Allergic Agents; Caffeine; Diuretics; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Lipids; Lung; Pharmacology; Research; Theobromine; Theophylline; Xanthine; Xanthines

1964
[1ST CLINICAL CONSIDERATIONS ON THE ASSOCIATION OF A SULFAMIDE DIURETIC AND A XANTHINE DERIVATIVE IN TREATMENT OF CARDIOPULMONARY DISEASES].
    Marseille medical, 1964, Volume: 101

    Topics: Biomedical Research; Diuretics; Drug Therapy; Heart Diseases; Humans; Obesity; Piperazines; Respiratory Insufficiency; Theophylline; Xanthine; Xanthines

1964
Raman spectroscopic characterisations and analytical discrimination between caffeine and demethylated analogues of pharmaceutical relevance.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2005, Volume: 61, Issue:7

    Topics: Alkaloids; Caffeine; Models, Chemical; Spectroscopy, Fourier Transform Infrared; Theobromine; Theophylline; Xanthine

2005
Two distinct pathways for metabolism of theophylline and caffeine are coexpressed in Pseudomonas putida CBB5.
    Journal of bacteriology, 2009, Volume: 191, Issue:14

    Topics: Caffeine; Gene Expression; Metabolic Networks and Pathways; Pseudomonas putida; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2009
Hydroxyl radical induced oxidation of theophylline in water: a kinetic and mechanistic study.
    Organic & biomolecular chemistry, 2014, Aug-14, Volume: 12, Issue:30

    Topics: Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Light; Mass Spectrometry; Methylation; Oxidation-Reduction; Pulse Radiolysis; Spectrum Analysis; Theophylline; Uric Acid; Water; Xanthine

2014
Synthesis and anticancer activity of silver(I)-N-heterocyclic carbene complexes derived from the natural xanthine products caffeine, theophylline and theobromine.
    Dalton transactions (Cambridge, England : 2003), 2015, Apr-28, Volume: 44, Issue:16

    Topics: Antineoplastic Agents; Biological Products; Caffeine; Cell Line, Tumor; Cell Survival; Coordination Complexes; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Hydrophobic and Hydrophilic Interactions; Methane; Molecular Conformation; Silver; Theobromine; Theophylline; Xanthine

2015
Different Catabolism Pathways Triggered by Various Methylxanthines in Caffeine-Tolerant Bacterium
    Journal of microbiology and biotechnology, 2018, Jul-28, Volume: 28, Issue:7

    Topics: Biodegradation, Environmental; Caffeine; Drug Tolerance; Gardens; Metabolic Networks and Pathways; Pseudomonas putida; Soil; Soil Microbiology; Substrate Specificity; Tea; Theobromine; Theophylline; Uric Acid; Xanthine; Xanthines

2018
Isolation, characterization and application of theophylline-degrading Aspergillus fungi.
    Microbial cell factories, 2020, Mar-19, Volume: 19, Issue:1

    Topics: Aspergillus; Biotransformation; Fermentation; Theophylline; Xanthine; Xanthines

2020